Molecular and Cellular Systems in Health and Disease

Molecular and Cellular Systems in Health and Disease seeks to understand the fundamental biological mechanisms that underpin health, disease and therapeutic intervention. The theme brings together expertise in structural biology, biochemistry, cell biology, molecular genetics, immunology, pharmacology and bioinformatics. Our researchers investigate protein structure and function, immune and inflammatory pathways, cellular signalling, metabolism, host-pathogen interactions, cancer biology and biomarker discovery. Work within the theme spans the molecular basis of infection and immunity, tumour development, metabolic disease and the development of new therapeutic approaches. By uncovering how biological systems function at the molecular and cellular level, the theme provides the knowledge base that underpins future advances in diagnosis, prevention and treatment.