Biography
I undertook both my BSc (Physics and Maths) and PhD (Protein Crystallography) at Keele University. The latter involved the development of synchrotron x-ray Laue method for use with large macromolecules such as proteins and viruses. I revisited Keele as a postdoctoral worker and was appointed as a Lecturer at Keele University in September 1999. I have been a visiting scientist at Purdue University, USA and LMB Cambridge and I have undertaken postdoctoral work in structural biology at Keele University, University of Edinburgh and Purdue University, USA.
Research and scholarship
My research interests are in structural biology and in how the structure of biological macromolecules is related to their function and is focused on the structure and function of key molecules of the innate immune system. The innate immune response has non-variable components which respond in a fairly general, often rapid manner to threatening microorganisms and molecules of both internal and external origin. A major focus of my research is on the three-dimensional structures of pentraxins and active fragments of collectins and related proteins and their interactions with natural ligands. Alongside structural work, we also aim to understand how these molecules are functioning in the immune system. From a clinical perspective, one aspect of this work includes analysis of possible modified forms of C-reactive protein in patient serum samples (REC reference 17/WM/0150). Further information on the work of the Structural Biology Research group can be found here.
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Human surfactant protein D |
FIBCD1 with bound ligand |
Human C-reactive protein - Image - T J Greenhough & A K Shrive © Keele University
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Teaching
Year 1
- LSC-10070 Clinical Applications of Biomedical Science
Year 2
- LSC-20015 Molecular, Cellular & Structural Immunology (Module manager)
Year 3
- LSC-30015 Biology of Disease (Module manager)
- LSC-30016 Structural Biology & Macromolecular Function
- LSC-30026 Case Studies in Biomedical Sciences
- LSC-30045 Life Sciences Double Experimental Project
- LSC-30050 Life Sciences Dissertation
Publications
School address
School of Life Sciences
Huxley Building
Keele University
Staffordshire
ST5 5BG
Tel: +44 (0) 1782 734414
Email: lifesciences.office@keele.ac.uk
Accessibility
Accessibility information for Huxley Building can be found on its AccessAble page.
Technical Manager: Chris Niles
Faculty Operations Manager: Maria Kyriacou
Enquiries
Tel: +44 (0) 1782 734414
Email: lifesciences.office@keele.ac.uk
Health and safety
Health and Safety Lead
Dr M Skidmore
Human Tissue Authority License
Dr D Tonge
Biological Safety Officer (University Level)
Ms R Harrison
Staff wellbeing champion
Dr Jenny Moran
A full list of School staff is available with details of individual room and telephone numbers, email addresses, details of research interests and other information.
Programme directors
Bioengineering (Regenerative Medicine)
Abigail
Tel: +44 (0) 1782 674085
Email: a.v.rutter@keele.ac.uk
Biology
David Hulse
Tel: +44 (0)1782 733640
Email: d.r.hulse@keele.ac.uk
Bioveterinary Science
Dr N Kareem
Tel: +44 (0)1782 733671
Email: n.o.kareem1@keele.ac.uk
Biochemistry
Dr David Watson
Tel: +44 (0)1782 733676
Email: d.watson@keele.ac.uk
Biomedical Science
Glenn Hussey (Admissions Tutor)
Tel: +44 (0)1782 733880
Email: g.d.hussey@keele.ac.uk
Ecology and Conservation
Jamie Pringle
Email: j.k.pringle@keele.ac.uk
Environmental Science
Michael Montenari
Tel: +44 (0) 1782 733162
Email: m.montenari@keele.ac.uk
Human Biology
Dr Mirna Mourtada (Admissions tutor)
Tel: +44 (0)1782 733679
Email: m.m.maarabouni@keele.ac.uk
Geography
Angie Turner
Tel: +44 (0) 1782 733620
Email: a.c.turner@keele.ac.uk
Geology
Steve Rogers
Tel: +44 (0) 1782 733752
Email: s.l.rogers@keele.ac.uk
Geology and Physical Geography
Steve Rogers
Tel: +44 (0) 1782 733752
Email: s.l.rogers@keele.ac.uk
Life Sciences
Research Centre Lead: Dr Helen Price
PGR Lead: Dr Marcelo Lima
Email: h.price@keele.ac.uk, m.andrade.de.lima@keele.ac.uk
Neuroscience
Dr Chris Adams
Tel: +44 (0)1782 733943
Email: c.adams@keele.ac.uk
Microbiology and Immunology
Dr Jenny Moran
Tel: +44 (0)1782 733594
Email: j.a.moran@keele.ac.uk
Neuroscience
Dr Chris Adams
Tel: +44 (0)1782 733943
Email: c.adams@keele.ac.uk
Pharmacology
Dr A Winter
Tel: +44 (0)1782 733117
Email: a.winter@keele.ac.uk
Sustainability and Environmental Management
Michael Montenari
Tel: +44 (0) 1782 733162
Email: m.montenari@keele.ac.uk