Selected Publications
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Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction. ACS Cent Sci, 527-545, vol. 8(5). link> doi> full text>2022.
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The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models. Front Pharmacol, 660490, vol. 12. link> doi> full text>2021.
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Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer's Disease β Secretase, BACE1. Mar Drugs, vol. 19(4). link> doi> full text>2021.
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Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin. Thromb Haemost, 1700-1715, vol. 120(12). link> doi> full text>2020.
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Chemical synthesis of a sulfated d-glucosamine library and evaluation of cell proliferation capabilities. Carbohydr Res, 108085, vol. 495. link> doi> full text>2020.
Full Publications Listshow
Journal Articles
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Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction. ACS Cent Sci, 527-545, vol. 8(5). link> doi> full text>2022.
-
The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models. Front Pharmacol, 660490, vol. 12. link> doi> full text>2021.
-
Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer's Disease β Secretase, BACE1. Mar Drugs, vol. 19(4). link> doi> full text>2021.
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Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin. Thromb Haemost, 1700-1715, vol. 120(12). link> doi> full text>2020.
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Chemical synthesis of a sulfated d-glucosamine library and evaluation of cell proliferation capabilities. Carbohydr Res, 108085, vol. 495. link> doi> full text>2020.
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Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain. doi>2020.
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SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins. doi>2020.
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Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin. doi>2020.
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Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides. Nature Communications, Article 1481, vol. 11(1). link> doi> link> full text>2020.
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The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding. doi>2020.
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Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus. Neural Regen Res, 1546-1553, vol. 15(8). link> doi> full text>2020.
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Tools for the Quality Control of Pharmaceutical Heparin. Medicina (Kaunas), vol. 55(10). link> doi> full text>2019.
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A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease. Mar Drugs, vol. 17(5). link> doi> full text>2019.
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A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence. PLoS One, e0186276, vol. 12(10). link> doi> full text>2017.
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Sulfatase-mediated manipulation of the astrocyte-Schwann cell interface. Glia, 19-33, vol. 65(1). link> doi> full text>2017.
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