Biography

Having graduated from Melli University Bio/Medical Sciences and successfully completed diplomas in French, English and German Languages, Ella has embarked on an MSc in Molecular Genetics at Leicester University. Her PhD in Neuroscience was completed at the Tierärztliche Hochschule Hannover in conjunction with the Medical University of Hannover. Before taking an appointment as a lecturer in neuroscience at Keele University, she worked as a research fellow (neuroscience) at the Legacy Health Research Hospital, Portland Oregon, USA and as a lecturer /researcher (neuroscience) at the University of Manchester, Manchester, UK where she completed a few translational research projects of which two have successfully been taken to clinical trials in stroke and schizophrenia.

Her research interest is in neuroinflammation, neuroregeneration and repair and she has investigated the role of progenitor cells, ion channels, inflammatory and small signalling molecules in diseases of the nervous system such as multiple sclerosis, stroke, Alzheimer’s, pain and schizophrenia (in vitro as well as in vivo). Currently, she is affiliated with University of Sheffield and has analysed clinical data on diseases of the aging population i.e. dementia, cardiovascular disease and comorbidities using UK-BioBank.

She has a Fellowship in teaching from Higher Education Academy (FHEA) and teaches across L4 - L7 neuroscience, cognitive neuroscience, and biomedical sciences; supervises undergraduate and postgraduate research projects and dissertations (L6 & L7); and leads the neuropharmacology (L5) and the special senses (L6) modules. She is the academic mentor of over 30 students and has mentored undergraduates, post-graduates, junior lecturers and postdocs over the years of which some have become successful medics, MRC research fellows or EPSRC research fellows.

Ella is the Academic Mentor of (L6) third year neuroscience students, deputising for the programme director (neuroscience), and has been appointed as the Library Liaison for the School of Life Sciences (2020-21). She is an active member of ENERI (ethics) and has been the reviewing editor of Frontiers in molecular neuroscience, Frontiers in cellular neuroscience, Stroke, Archives of Medical Sciences, and Experimental Neurology since 2005.

Potential MSc or PhD candidate can contact her office to discuss.

Teaching

Postgraduate: MSc/MPhil Teaching

Undergraduate Year 1 Teaching (level 4)

Undergraduate Year 2 Teaching (level 5)

  • LSC-20061 Neuropharmacology: module leader, lecturer, and first examiner
  • LSC-20079 Neuroanatomy: lecturer and first examiner
    • Limbic system
    • Hypothalamus
  • LSC-20078 Neuroscience Research Methods: lecturer and first examiner
  • LSC-20107 Practical Skills in Bioscience: lecturer
    • Semester 1: spinal cord anatomy practical,
    • Semester 2:
      • ethics in neuroscience practical,
      • health informatics practical,
      • bioinformatics practical
  • LSC-20085 Cell Signalling: first examiner (neuroscience students)
    • Signalling of inflammatory molecules in stroke pathology

Undergraduate Year 3 Teaching (level 6)

  • LSC-30063 Brain Disease: module leader, lecturer and first examiner
    • Cellular and molecular mechanisms of neurological and neuropsychiatric disorders
    • Stroke pathology
    • Schizophrenia pathology
    • Infectious diseases of the nervous system: Meningitis
    • Brain tumours: benign and malignant
    • Pathologies of CSF circulation: Hydrocephalus
    • Problem based learning tutorials
  • LSC-30053 Special Senses: module leader, lecturer, and first examiner
    • Neuroscience of hearing and disorders of hearing system
    • Vision neuroscience and disorders of visual system
    • Disorders of vestibular system
    • Gustation & olfaction disorders
    • Neurological disorders that affect special senses
    • Journal comprehension
  • LSC-30042 Current Research Topicsin neuroscience: lecturer and first examiner
    • Neuroinflammation and stroke regeneration (translational & clinical research)
  • LSC-30052 Behavioural Neuroscience: Lecturer and first examiner
    • Chemical regulation of behaviour
    • Hypothalamus and feeding
    • Stress, development, and cognition
    • Sensory processing, touch, and pain
    • Biological rhythms
    • Ageing and cognition
    • Homeostasis
  • LSC-30015 The Biology of Disease: Topic specific first examiner. This module does not contain any lectures.
    • Nanotechnology, BBB, and treatment of epilepsy
    • Pathophysiology of insomnia
    • Genomics and epigenomics of dementia
    • Chemokine signalling and pathophysiology of multiple sclerosis
    • Acid sensing ion channels and nervous system pathologies
  • LSC-30039 Regeneration and Repair in the Nervous System: lecturer and first examiner
    • Neuroinflammation, regeneration and repair (translational and clinical)
    • Oligodendrocytes in multiple sclerosis regeneration (translational neuroscience)
  • LSC-30045 Life Sciences Double Experimental Project: supervisor
  • LSC-30048 Life Sciences Single Experimental Project: supervisor
  • LSC-30050 Neuroscience Dissertation: supervisor

Laboratory Project Students (2021-22): LSC 30045, 30048, 30050

  • Benjamin Geary (EEG changes in Parkinson’s patients) clinical data
  • Bence Balogh (EEG changes in Parkinson’s patients) clinical data
  • Stefanie Johnson Medina (EEG changes in Parkinson’s patients) Systematic review
  • Yukta Patel (EEG changes in Parkinson’s patients) clinical data
  • Breanna Sharifian (EEG changes in Parkinson’s patients) clinical data       
  • Elakiya Annadurai (EEG changes in Parkinson’s patients) Systematic review
  • Madison Hanney (EEG changes in Parkinson’s patients) Systematic review
  • Sophie Katsiavriades (Companion diagnostic biomarkers in spinal cord injury)
  • Osiah Ndlovu (EEG changes in Parkinson’s patients) clinical data
  • Fareeha ahmad (EEG changes in Parkinson’s patients) Systematic review

Laboratory Project Students (2020-21): : LSC 30045, 30048, 30050

  • Carla Simon (neuroscience student) – current post: MSc in neuroscience (Vrije Universiteit Amsterdam)
  • Nadine Hohn (neuroscience student) linkedincurrent post: MSc in neuroscience (University of Manchester)
  • Xheni Prebibaj (neuroscience student) linkedinpositions: Demographic Project Researcher at Smith-Magenis Syndrome (SMS) Foundation. Current post: Associate Consultant at Strategic Analytics
  • Sernila Ganeshamoorthy (biomed student) linkedin– current post: Business Development Specialist at Medidata Solutions
  • Suldan Hassan
  • Apisan Thuishyanthan
  • Ahmad Arif
  • Darcey Paskin
  • Heera Tariq

Laboratory Project Students (2019-20): LSC 30045, 30048, 30050

  • Charlotte Goodman (Biology student)- Postgraduate in Cancer Research and Molecular Biomedicine at Uni of Manchester (2020-21), current post: Associate Scientist in Early Discovery | Charles River Laboratories
  • Sophie Douglas [Linkedin] - positions: Postgraduate in Medical Microbiology at Keele Uni (2020-21), Genetic technologist Genetic technologist Oncologica UK (2021-22), current post: Cell line development Scientist, Cell line development Scientist at Abzena
  • Piraveenth Kenkarajah
  • James Rumball
  • Alina Khan – current post: Clinical Trials Technician at Synexus
  • Luke Doughty (neuroscience student) – current post: Postgraduate in Molecular Neuroscience at Bristol Uni (2020-21)
  • Simon Johnson

Further information

Dr Ella Maysami KIITE conference

Dr Maysami presented at KIITE Education Conference in Jan 2022
Host: Keele Institute for Innovation and Teaching Excellence (hyperlink to: https://viewer.joomag.com/keele-education-conference-2022-programme/0498042001639744125?short&)
Title: Designing authentic assessments: Moving away from essays and educating for global competence (case-study)
Date/Time: 14 January 2022, 10:15-10:30 Keele Education Conference 2022 - Keele University

ella-mayasami-covid-talk

Dr Maysami chaired a session on LONG COVID
Host: Midlands Immunology Network
Title: The COVID-19 Research Showcase 2 - LONG COVID 
Date/Time: 16 September 2021, 13:00-17:00

jove video link

Hybrid Teaching and Learning Post-Pandemic: How to make the Most of Educational Videos
Host: JoVE (Journal of Visualized Experiments)
Title: Hybrid Teaching and Learning Post-Pandemic: How to Make the Most of Educational Videos
Date / Time: Wednesday 23 June | Time: 2 PM BST (UK) // 4 PM Israel 

Blended learning lab

Blended teaching and learning in laboratory sessions (KIITE Conference - January 2021, Keele University)
Host: KITE, Keele University - ‘Education: Then. Now. Next’
Title: Delivering laboratory  practical sessions using a hybrid approach - (Case study) by Dr Ella Maysami & Samirah Chowdhury (Level 5 neuroscience student)
Date / Time: 20 January 2021

Blended learning medical

Blended teaching at Medical Schools: Reflecting on pedagogical research reports (pre and post covid)
Host: School of Life Sciences, Internal Communication (Education and Scholarship Team - Away Day)
Title: Blended Learning in Higher Education
Date and Time: 5 August 2020

Selected Publications

  • Orset C, Haelewyn B, Allan SM, Ansar S, Campos F, Cho TH, Durand A, El Amki M, Fatar M, Garcia-Yébenes I, Gauberti M, Grudzenski S, Lizasoain I, Lo E, Macrez R, Margaill I, Maysami S, Meairs S, Nighoghossian N, Orbe J, Paramo JA, Parienti J-J, Rothwell NJ, Rubio M, Waeber C, Young AR, Touzé E, Vivien D. 2016. Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis. Stroke, 1312-1318, vol. 47(5). link> doi>
  • Orset C, Le Béhot A, Bonnet A-L, Maysami S, Vivien D. Mouse Model of In Situ Thromboembolic Stroke and Reperfusion. In Rodent Models of Stroke. Dirnagl U (Ed.). Humana Press, New York, NY: Springer. doi> link>
  • Neill J, Harte M, Grayson B, Maysami S, Williams S, Mckie S, Deakin B, Leger M, Cunningham M, LeBeau F, Gillougley C, Tarazi F, Alvaro G, Large C. 2015. Development of AUT00206, a Novel and Selective Kv3 Channel Modulator for the Treatment of Schizophrenia. NEUROPSYCHOPHARMACOLOGY (pp. S205-S206, vol. 40). link>
  • Maysami S, Wong R, Pradillo JM, Denes A, Dhungana H, Malm T, Koistinaho J, Orset C, Rahman M, Rubio M, Schwaninger M, Vivien D, Bath PM, Rothwell NJ, Allan SM. 2016. A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke. J Cereb Blood Flow Metab, 596-605, vol. 36(3). link> doi> full text>
  • Maysami S, Haley MJ, Gorenkova N, Krishnan S, McColl BW, Lawrence CB. 2015. Prolonged diet-induced obesity in mice modifies the inflammatory response and leads to worse outcome after stroke. J Neuroinflammation, 140, vol. 12. link> doi> full text>

Full Publications Listshow

Journal Articles

  • Orset C, Haelewyn B, Allan SM, Ansar S, Campos F, Cho TH, Durand A, El Amki M, Fatar M, Garcia-Yébenes I, Gauberti M, Grudzenski S, Lizasoain I, Lo E, Macrez R, Margaill I, Maysami S, Meairs S, Nighoghossian N, Orbe J, Paramo JA, Parienti J-J, Rothwell NJ, Rubio M, Waeber C, Young AR, Touzé E, Vivien D. 2016. Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis. Stroke, 1312-1318, vol. 47(5). link> doi>
  • Maysami S, Wong R, Pradillo JM, Denes A, Dhungana H, Malm T, Koistinaho J, Orset C, Rahman M, Rubio M, Schwaninger M, Vivien D, Bath PM, Rothwell NJ, Allan SM. 2016. A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke. J Cereb Blood Flow Metab, 596-605, vol. 36(3). link> doi> full text>
  • Maysami S, Haley MJ, Gorenkova N, Krishnan S, McColl BW, Lawrence CB. 2015. Prolonged diet-induced obesity in mice modifies the inflammatory response and leads to worse outcome after stroke. J Neuroinflammation, 140, vol. 12. link> doi> full text>
  • Rodriguez-Grande B, Swana M, Nguyen L, Englezou P, Maysami S, Allan SM, Rothwell NJ, Garlanda C, Denes A, Pinteaux E. 2014. The acute-phase protein PTX3 is an essential mediator of glial scar formation and resolution of brain edema after ischemic injury. J Cereb Blood Flow Metab, 480-488, vol. 34(3). link> doi>
  • Leow-Dyke S, Allen C, Denes A, Nilsson O, Maysami S, Bowie AG, Rothwell NJ, Pinteaux E. 2012. Neuronal Toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro. J Neuroinflammation, 230, vol. 9. link> doi> full text>
  • Lin J, Chu X, Maysami S, Li M, Si H, Cottrell JE, Simon RP, Xiong Z. 2011. Inhibition of acid sensing ion channel currents by lidocaine in cultured mouse cortical neurons. Anesth Analg, 977-981, vol. 112(4). link> doi>
  • Maysami S, Lan JQ, Minami M, Simon RP. 2008. Proliferating progenitor cells: a required cellular element for induction of ischemic tolerance in the brain. J Cereb Blood Flow Metab, 1104-1113, vol. 28(6). link> doi>
  • Pignataro G, Maysami S, Studer FE, Wilz A, Simon RP, Boison D. 2008. Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism. J Cereb Blood Flow Metab, 17-23, vol. 28(1). link> doi>
  • Maysami S, Nguyen D, Zobel F, Heine S, Höpfner M, Stangel M. 2006. Oligodendrocyte precursor cells express a functional chemokine receptor CCR3: implications for myelination. J Neuroimmunol, 17-23, vol. 178(1-2). link> doi>
  • Heine S, Ebnet J, Maysami S, Stangel M. 2006. Effects of interferon-beta on oligodendroglial cells. J Neuroimmunol, 173-180, vol. 177(1-2). link> doi>
  • Maysami S, Nguyen D, Zobel F, Pitz C, Heine S, Höpfner M, Stangel M. 2006. Modulation of rat oligodendrocyte precursor cells by the chemokine CXCL12. Neuroreport, 1187-1190, vol. 17(11). link> doi>

Chapters

  • Orset C, Le Béhot A, Bonnet A-L, Maysami S, Vivien D. Mouse Model of In Situ Thromboembolic Stroke and Reperfusion. In Rodent Models of Stroke. Dirnagl U (Ed.). Humana Press, New York, NY: Springer. doi> link>
  • Maysami S and Stangel M. 2004. Chapter 4 - Treatment Approaches Toward Remyelination In Multiple Sclerosis (pp. 65-87). In Treatment and Management of Multiple Sclerosis. Columbus F (Ed.). Nova Publishers. link>

Other

  • Neill J, Harte M, Grayson B, Maysami S, Williams S, Mckie S, Deakin B, Leger M, Cunningham M, LeBeau F, Gillougley C, Tarazi F, Alvaro G, Large C. 2015. Development of AUT00206, a Novel and Selective Kv3 Channel Modulator for the Treatment of Schizophrenia. NEUROPSYCHOPHARMACOLOGY (pp. S205-S206, vol. 40). link>
  • Large C, Leger M, Harte M, Gillougley C, Maysami S, McKie S, LeBeau F, Cunningham M, Williams S, Alvaro G, Neill J. 2015. KV3 MODULATORS FOR THE TREATMENT OF SCHIZOPHRENIA. SCHIZOPHRENIA BULLETIN (p. S319, vol. 41). link>
  • Stangel M, Lindner M, Pitz C, Heine S, Maysami S. 2005. Expression of the chemokine receptor CXCR2 during remyelination and its influence on oligodendrocytes. MULTIPLE SCLEROSIS (p. S136, vol. 11). link>

Collaborations and grants awards

2020-21 (UK)
Co-supervisor of the PhD student, Emad Shaquora, in collaboration with Professor Anand Pandyan
Project: Spinal Cord Injury (clinical recovery, intervention study) - Faculty of Medicine, Keele University
Co-supervisor of the MSc student, Casey Shaw, in collaboration with Professor Ying Yang
Project: Spinal Cord Injury (preclinical project, intervention study) - School of Pharmacy and Bioengineering, Keele University

Dec 2020 (UK)
MRC - UKRI World Class Laboratories (WCL) Grant
Co-applicant (Dr Melissa Bowerman; Professor Divya Chari; Dr Stuart Jenkins; Dr Chris Adams; Dr Stefanie Jones; Dr Ruoli Chen; Dr Simon Trent; Dr Ella Maysami)
Amount £68K (excl. VAT)

Sep 2018 (UK)
Social Responsibility Award
In recognition of public engagement activities (University of Manchester)

Sep 2015 (UK)
Social Responsibility Award
In recognition of public engagement activities (University of Manchester)

Sep 2011 (UK)
Research Staff Association Award
Hosting a Cross-disciplinary conference at University of Manchester
Co-applicant (Dr Kassandra Papadopoulou; Dr Sarah King-Hele; Dr Samaneh Maysami, Isabelle Darmon)
Amount £2K

Sep 2007 (USA)
Legacy Health Research Hospital RAC Grant
PI: Investigating the role of inflammatory molecules in ischemic stroke
Amount $8K

Sep 2005 (Italy)
Symbionic - Conference Grant
Amount €1K

Memberships

She is an active member of European Network of Research Ethics and Research Integrity” (ENERI)
2015 - current Reviewer of Frontiers Neuroscience: Critical appraisal (Neuroscience)
2018 - current Reviewer of Stroke 2018: Critical appraisal (Neuroscience)
2005 - current Reviewer of Archives of Medical Sciences: Critical appraisal (Medicine)
2005 - current Reviewer of Experimental Neurology: Critical appraisal (Neuroscience)

Other affiliations:

University of Sheffield (Health Informatics, School of Social Sciences)
Society for Neuroscience (SFN)
Federation of European NeuroScience (FENs)
German Neuroscience Society (NWG)
School Governor at Ashgate Specialist Support Primary School in Manchester
STEM Ambassador at MOSI in Manchester

Research Opportunities

The following research projects are available to prospective MSc or PhD students. Click on each project to read more:

Project 1Evaluating the contributing factors in psychological disorders such as depression, schizophrenia, bipolar disorders ...

Project 2Evaluating the contributing factors in dementia among the UK’s aging population.

Project 3 - Evaluating the effect of drugs and small molecules on neuronal and glial cells.

Project 4 - Evaluating the effects of drugs/ small molecules on rodents’ behaviour.      

If you wish to complete your PhD in Ella's lab you can apply for PhD studentship at https://www.brainresearchuk.org.uk/research/apply/phd-studentship - the funding is available to home and overseas student applicants at UK/EU level. If you have a specific project in mind, please approach her to discuss. Note that the deadline for this scholarship is fast approaching (5th Nov 2020) - (last update on 24th Sep 2020).

School of Life Sciences,
Huxley Building,
Keele University,
Staffordshire,
ST5 5BG
Tel: +44 (0) 1782 734414