Biography

I obtained a first class BSc (Hons) in Pharmacology with Industrial Experience from the University of Edinburgh. As part of my degree I spent time in industry developing drug safety assays. For my PhD in Cardiac Physiology (The University of Manchester) I characterised structural, autonomic and extracellular remodelling in ageing and heart failure using an ovine tachypacing model. As a Postdoctoral Research Associate in the School of Medicine (University of Manchester) I investigated collagen and elastin remodelling in the development and recovery from heart failure. For this project I was awarded the BSCR Bernard and Joan Marshall Young Investigator prize.

I came to Keele to pursue a full-time teaching role as an Associate Teaching Fellow in Bioscience and later promoted to Teaching Fellow. In 2019 I became a Lecturer (E&S) in Bioscience specialising in physiology and pharmacology.

Research and scholarship

My previous research focused on extracellular matrix remodelling in both the ageing and diseased heart.

At Keele I am studying for an MA in Learning and Teaching in Higher Education. My action research project focuses on the use of bespoke, quiz-integrated animated videos in the enhancement of student engagement and learning.

Teaching

I teach on the Keele University MBChB programme as well as the MSc Physician’s Associate (PA) studies. I lecture on both the physiology and pharmacology strands of these courses and I specialise in the cardiovascular system. I am lead for the Year 2 unit “Circulation” as well as the Year 3 SPINE sessions on neuropharmacology. I lead Multi-Sourced Feedback (MSF) for years 1 and 2 and I am a tutor for problem-based learning (PBL) and Enhanced Professional and Academic Student Support (EPASS).

Selected Publications

  • Horn M. 2020. Re-designing preclinical neuropharmacology teaching to enhance student engagement and active learning. Journal of Academic Development and Education. full text>
  • Horn MA, Bode EF, Borland SJ, Kirkwood GJ, Briston SJ, Richards MA, Dibb KM, Trafford AW. 2016. Temporal Development of Autonomic Dysfunction in Heart Failure: Effects of Age in an Ovine Rapid-pacing Model. J Gerontol A Biol Sci Med Sci, 1544-1552, vol. 71(12). link> doi>
  • Horn MA and Trafford AW. 2016. Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling. J Mol Cell Cardiol, 175-185, vol. 93. link> doi>
  • Horn MA. 2015. Cardiac Physiology of Aging: Extracellular Considerations. Compr Physiol, 1069-1121, vol. 5(3). link> doi>
  • Clarke JD, Caldwell JL, Horn MA, Bode EF, Richards MA, Hall MCS, Graham HK, Briston SJ, Greensmith DJ, Eisner DA, Dibb KM, Trafford AW. 2015. Perturbed atrial calcium handling in an ovine model of heart failure: potential roles for reductions in the L-type calcium current. J Mol Cell Cardiol, 169-179, vol. 79. link> doi>

Full Publications Listshow

Journal Articles

  • Horn M. 2020. Re-designing preclinical neuropharmacology teaching to enhance student engagement and active learning. Journal of Academic Development and Education. full text>
  • Horn MA, Bode EF, Borland SJ, Kirkwood GJ, Briston SJ, Richards MA, Dibb KM, Trafford AW. 2016. Temporal Development of Autonomic Dysfunction in Heart Failure: Effects of Age in an Ovine Rapid-pacing Model. J Gerontol A Biol Sci Med Sci, 1544-1552, vol. 71(12). link> doi>
  • Horn MA and Trafford AW. 2016. Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling. J Mol Cell Cardiol, 175-185, vol. 93. link> doi>
  • Horn MA. 2015. Cardiac Physiology of Aging: Extracellular Considerations. Compr Physiol, 1069-1121, vol. 5(3). link> doi>
  • Clarke JD, Caldwell JL, Horn MA, Bode EF, Richards MA, Hall MCS, Graham HK, Briston SJ, Greensmith DJ, Eisner DA, Dibb KM, Trafford AW. 2015. Perturbed atrial calcium handling in an ovine model of heart failure: potential roles for reductions in the L-type calcium current. J Mol Cell Cardiol, 169-179, vol. 79. link> doi>
  • Horn MA, Graham HK, Richards MA, Clarke JD, Greensmith DJ, Briston SJ, Hall MCS, Dibb KM, Trafford AW. 2012. Age-related divergent remodeling of the cardiac extracellular matrix in heart failure: collagen accumulation in the young and loss in the aged. J Mol Cell Cardiol, 82-90, vol. 53(1). link> doi>
  • Briston SJ, Caldwell JL, Horn MA, Clarke JD, Richards MA, Greensmith DJ, Graham HK, Hall MCS, Eisner DA, Dibb KM, Trafford AW. 2011. Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure. J Physiol, 1367-1382, vol. 589(Pt 6). link> doi>
  • Dibb KM, Clarke JD, Horn MA, Richards MA, Graham HK, Eisner DA, Trafford AW. 2009. Characterization of an extensive transverse tubular network in sheep atrial myocytes and its depletion in heart failure. Circ Heart Fail, 482-489, vol. 2(5). link> doi>
  • Graham HK, Horn M, Trafford AW. 2008. Extracellular matrix profiles in the progression to heart failure. European Young Physiologists Symposium Keynote Lecture-Bratislava 2007. Acta Physiol (Oxf), 3-21, vol. 194(1). link> doi>

Other

  • Ali N, Crawford R, Horn M. 2019. Critical thinking in PBL: Development of a bespoke tool for critical thinking. 5TH INTERNATIONAL CONFERENCE ON HIGHER EDUCATION ADVANCES (HEAD'19) (pp. 513-520). link> doi>