Professor Serguei Y Semenov

Title: Professor of Imaging
MS Physics, PhD Radiobiology and Physics,
DSc Physics in Medical Imaging
Phone: +44 (0)1782 674988
Email: s.semenov@keele.ac.uk
Location: Institute for Science & Technology in Medicine, Keele University,
Guy Hilton Research Centre, Thornburrow Drive, Hartshill, Stoke-on-Trent ST4 7QB United Kingdom
Role: ISTM Research theme: Diagnostic Engineering & Proteomics
Contacting me: By phone or email
Prof Serguei Semenov

Education:

Professional Experience:

  • 1992 – 2005 Carolinas Medical Center, Charlotte, NC, USA - Director of the Biophysical Laboratory.
  • 1990 – 2000 Kurchatov Institute of Atomic Energy, Moscow, Russia – Director of the Laboratory of Applied Biophysics
  • 1988 – 1990, Kurchatov Institute of Atomic Energy, Moscow, Russia – Senior Research Scientist
  • 1985 – 1988, Institute of Biophysics, Moscow, – Research Scientist
  • 1982 – 1985, Institute of Biophysics, Moscow, Russia – Postgraduate Fellow

ISTM Research theme: Diagnostic Engineering & Proteomics

Research Interests:

Professor Semenov’s research explores biomedical electromagnetic imaging and spectroscopy technologies, covering microwave, optical and electrical impedance techniques. These approaches allow for development of novel imaging modalities for rapid functional imaging including non-invasive assessment of tissue blood and oxygen content, circulation, tissue ischemia and infarction, malignancies, compartment syndrome in extremities and others.

Professor Semenov moved to Keele University in March 2006 from the Carolinas Medical Centre, Charlotte NC, USA. Within ISTM he is a member of the Diagnostic Engineering & Proteomics research theme and has active collaboration in his research with clinicians at the University Hospital of North Staffordshire (UHNS) including Dr Paula Richards, Prof Christine RoffeDr Josep Sule Suso and Professor Monica Spiteri.

Current Projects:

Professor Semenov has recently focused on the research and development of 4D Electromagnetic Tomography (EMT), a microwave imaging technology for clinical use. This includes an allocation of proper funding sources, research and development of antennas, phased arrays, detectors and sensors, manufacture of prototype(s) of clinically viable systems, improvement of image reconstruction algorithms of diffraction tomography, image analysis, tissue electromagnetic spectroscopy and modelling and compliance with regulations.  Recent successful experiments have led to human trials, due to commence in UHNS in spring 2014. The technology is being exploited by EMImaging LLC and aims to detect blood embolisms following stroke. The EMT instrument will be located in mobile ambulances with remote instantaneous on line transfer and interpretation from a central clinical unit in Europe.

An interaction of non-ionizing electromagnetic radiation with biological tissues, including cardiac excited tissues and bioelectromagnetics of such tissues, are other ongoing projects. His future focus is on combined, multimodality functional imaging, both for clinical use and small animal imaging.

Selected Publications

  • Bindu G and Semenov S. 2013. 2-D Fused Image Reconstruction approach for Microwave Tomography: a theoretical assessment using FDTD Model. Comput Methods Biomech Biomed Eng Imaging Vis, vol. 1(3), 147-154. link> doi>
  • Lai KT, Nair BG, Semenov S. 2012. OPTICAL AND MICROWAVE STUDIES OF FERROELECTRIC NANOPARTICLES FOR APPLICATION IN BIOMEDICAL IMAGING. MICROWAVE AND OPTICAL TECHNOLOGY LETTERS, vol. 54(1), 11-13. link> doi>
  • Semenov S, Kellam J, Sizov Y, Nazarov A, Williams T, Nair B, Pavlovsky A, Posukh V, Quinn M. 2011. Microwave tomography of extremities: 1. Dedicated 2D system and physiological signatures. Phys Med Biol, vol. 56(7), 2005-2017. link> doi>
  • Semenov S, Kellam J, Nair B, Williams T, Quinn M, Sizov Y, Nazarov A, Pavlovsky A. 2011. Microwave tomography of extremities: 2. Functional fused imaging of flow reduction and simulated compartment syndrome. Phys Med Biol, vol. 56(7), 2019-2030. link> doi>
  • Semenov S, Kellam J, Williams T, Quinn M, Nair BG, IEEE. 2010. 2D microwave tomographic system for extremities imaging: initial performance assessment in animal trial. PROCEEDINGS OF THE FOURTH EUROPEAN CONFERENCE ON ANTENNAS AND PROPAGATION. link>

Full Publications List show

Journal Articles

  • Bindu G and Semenov S. 2013. 2-D Fused Image Reconstruction approach for Microwave Tomography: a theoretical assessment using FDTD Model. Comput Methods Biomech Biomed Eng Imaging Vis, vol. 1(3), 147-154. link> doi>
  • Lai KT, Nair BG, Semenov S. 2012. OPTICAL AND MICROWAVE STUDIES OF FERROELECTRIC NANOPARTICLES FOR APPLICATION IN BIOMEDICAL IMAGING. MICROWAVE AND OPTICAL TECHNOLOGY LETTERS, vol. 54(1), 11-13. link> doi>
  • Semenov S, Kellam J, Sizov Y, Nazarov A, Williams T, Nair B, Pavlovsky A, Posukh V, Quinn M. 2011. Microwave tomography of extremities: 1. Dedicated 2D system and physiological signatures. Phys Med Biol, vol. 56(7), 2005-2017. link> doi>
  • Semenov S, Kellam J, Nair B, Williams T, Quinn M, Sizov Y, Nazarov A, Pavlovsky A. 2011. Microwave tomography of extremities: 2. Functional fused imaging of flow reduction and simulated compartment syndrome. Phys Med Biol, vol. 56(7), 2019-2030. link> doi>
  • Semenov S. 2009. Microwave tomography: review of the progress towards clinical applications. Philos Trans A Math Phys Eng Sci, vol. 367(1900), 3021-3042. link> doi>
  • Egot-Lemaire S, Pijanka J, Sulé-Suso J, Semenov S. 2009. Dielectric spectroscopy of normal and malignant human lung cells at ultra-high frequencies. Phys Med Biol, vol. 54(8), 2341-2357. link> doi>
  • Semenov S, Kellam J, Althausen P, Williams T, Abubakar A, Bulyshev A, Sizov Y. 2007. Microwave tomography for functional imaging of extremity soft tissues: feasibility assessment. Phys Med Biol, vol. 52(18), 5705-5719. link> doi>
  • SEMENOV S, Abubakar A, Bulyshev AE, Posukh VG. 2005. Microwave-Tomographic Imaging of the High Dielectric-Contrast Objects Using Different Image-Reconstruction Approaches. Microwave Theory and Techniques, IEEE Transactions on, vol. 53(7), 2284-2294. doi>
  • SEMENOV S, Bulyshev AE, Posukh VG, Sizov YE. 2003. Microwave Tomography for Detection/Imaging of Myocardial Infarction. I. Excised Canine Hearts. Annals of Biomedical Engineering, vol. 31(3), 262-270. doi>
  • SEMENOV S, Chen W, Posukh VG, Svenson RH. 2002. Dielectrical spectroscopy of canine myocardium during acute ischemia and hypoxia at frequency spectrum from 100 kHz to 6 GHz. Medical Imaging, IEEE Transactions on, vol. 21(6), 703-707. doi>
  • SEMENOV S, Boulyshev AE, Souvorov AE, Svenson RH. 2002. Three-dimensional microwave tomography: initial experimentalimaging of animals. IEEE Transaction on Biomedical Engineering, vol. 49(1), 55-63. doi>
  • Semenov S, Kellam, J, Sizov, Y, Nazarov, A, Williams, T. Microwave Tomographic Imaging System for Extremities Soft Tissues Imaging. World Congress on Medical Physics and Biochemical Engineering, Munich, Germany, vol. 25(2), 773-775. doi>
  • Semenov S and Corfield, DR. Microwave tomography for brain imaging. Feasibility assessment for stroke detection. International Journal of Antennas and Propagation, Article 254830. doi>

Other

  • Semenov S, Kellam J, Williams T, Quinn M, Nair BG, IEEE. 2010. 2D microwave tomographic system for extremities imaging: initial performance assessment in animal trial. PROCEEDINGS OF THE FOURTH EUROPEAN CONFERENCE ON ANTENNAS AND PROPAGATION. link>
  • Semenov S, Pham N, Egot-Lemaire S. 2009. Ferroelectric Nanoparticles for Contrast Enhancement Microwave Tomography: Feasibility Assessment for Detection of Lung Cancer. MICRO-AND NANOSYSTEMS IN MEDICINE, ACTIVE IMPLANTS, BIOSENSORS (vol. 25, pp. 311-313). link>
  • Semenov S, Kellam J, Sizov Y, Nazarov A, Williams T. 2009. Microwave Tomographic Imaging System for Extremities Soft Tissues Imaging. WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING, VOL 25, PT 2 - DIAGNOSTIC IMAGING (vol. 25, pp. 773-775). link>
  • Egot-Lemaire S, Bagnaninchi P-O, Pijanka J, Sule-Suso J, Semenov S. 2008. Microwave dielectric spectroscopy of low-volume fraction human cancer cells embedded in collagen gels - Experimental feasibility study with an open-ended coaxial probe. BIODEVICES 2008: PROCEEDINGS OF THE FIRST INTERNATIONAL CONFERENCE ON BIOMEDICAL ELECTRONICS AND DEVICES, VOL 2 (pp. 156-+). link>
  • Abubakar A, Semenov S, Posukh VG, van den Berg PM, IEEE. 2005. Application of the multiplicative regularized contrast source inversion method to real biological data. 2005 IEEE MTT-S International Microwave Symposium, Vols 1-4 (pp. 1319-1322). link> doi>
  • Semenov S, Posukh V, Bulyshev A, Sizov Y, Souvorov A, Williams T. 2003. Microwave tomography for biomedicine: Cardiovascular applications. MEDICAL PHYSICS (vol. 30, p. 1541). link>