Biography

Dr. Pooya Davoodi is a lecturer (Assistant Professor) in the School of Pharmacy and Bioengineering at Keele University (August 2020-now). He received his Ph.D. in Chemical and Biomolecular Engineering from National University of Singapore (NUS) in 2016. He did two years of Postdoctoral Fellowship in Chemical Engineering at NUS before joining the University of Cambridge as a research associate in Nov. 2018.

Over the past years, his research has focused on the synthesis and functionalisation, chemical characterisation and biological evaluation of polymeric biomaterials for drug delivery and tissue engineering. He has also been working on the development of micro-patterned tissue constructs using 3D bioprinting, electrospraying and electrospinning techniques.

Research and scholarship

My current research fucoses on three major areas I) Advanced Biomaterials To synthesise new biopolymers with stimuli-responsive properties suitable for on-demand and programmed drug delivery and tissue engineering. II) Drug Delivery To fabricate smart micro-/nano-particulate structures: A) to control the release of therapeutic agents at the site of action (e.g. cancer tumor) B) to provide a biomimetic extracellular microenvironment for promoting cell growth and differentiation via the controlled release of biochemicals and biomolecules (growth factors, proteins, DNA, etc.) III) Additive Manufacturing and 3D Bioprinting To develop and integrate macro-/micro-/nano-fabrication technologies for the design and fabrication of 3D tissue constructs and advanced drug delivery systems. We will use 3D bioprinting, electrospinning, and electrohydrodynamic atomization to fabricate: A) complex tissue architectures recapitulating important features of diseases and organ tissues in vivo B) novel drug delivery systems The technologies that we will develop have the potential to further apply for various organ tissue models with applications in personalised medicine. For further information, please visit our group website: https://davoodilab.weebly.com/

Teaching

I am currently teaching the following courses/subjects in the School of Pharmacy and Bioengineering: • PHA-10014 and PHA-10020: Biopharmaceutics • PHA-20009 and PHA-20018: Principles of Solid States (Particles, powders, granulation, drying, film coating) • PHA-30023 and PHA-30023: Ocular, Otic, Nasal Drug Delivery • PHA-40120 and PHA-30023: Advanced Pharmaceutics

Further information

Join us!

Master and PhD students

We welcome all interested SELF-FUNDED Master and PhD students. Please kindly send your CV to my email and state that you are self-funded​.

 

Visiting students

Applicants who are interested should send their CV and the name of one reference (your supervisor) to my email and state that you are a "self-funded visiting student". Also, please clearly state the source of funding. Candidates with background in drug delivery, biomaterials science, 3D bioprinting, and microfabrication are highly preferred.

Selected Publications

  • Zare M, Davoodi P, Ramakrishna S. 2021. Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications. Nanomaterials (Basel), vol. 11(4). link> doi> full text>
  • Zhang D, Davoodi P, Li X, Liu Y, Wang W, Huang YYS. 2020. An empirical model to evaluate the effects of environmental humidity on the formation of wrinkled, creased and porous fibre morphology from electrospinning. Sci Rep, 18783, vol. 10(1). link> doi> full text>
  • Teoh JH, Thamizhchelvan AM, Davoodi P, Ramasamy S, Vijayavenkataraman S, Yang Q, Dicolandrea T, Zhao H, Fuh JYH, Liou Y-C, Wang C-H. 2019. Investigation of the application of a Taylor-Couette bioreactor in the post-processing of bioprinted human dermal tissue. BIOCHEMICAL ENGINEERING JOURNAL, Article ARTN 107317, vol. 151. link> doi>
  • Li Z, Lei IM, Davoodi P, Huleihel L, Huang YYS. 2019. Solution Formulation and Rheology for Fabricating Extracellular Matrix-Derived Fibers Using Low-Voltage Electrospinning Patterning. ACS Biomater Sci Eng, 3676-3684, vol. 5(7). link> doi>
  • Lei C, Davoodi P, Zhan W, Chow PK-H, Wang C-H. 2019. Development of Nanoparticles for Drug Delivery to Brain Tumor: The Effect of Surface Materials on Penetration Into Brain Tissue. J Pharm Sci, 1736-1745, vol. 108(5). link> doi>

Full Publications Listshow

Journal Articles

  • Zare M, Davoodi P, Ramakrishna S. 2021. Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications. Nanomaterials (Basel), vol. 11(4). link> doi> full text>
  • Zhang D, Davoodi P, Li X, Liu Y, Wang W, Huang YYS. 2020. An empirical model to evaluate the effects of environmental humidity on the formation of wrinkled, creased and porous fibre morphology from electrospinning. Sci Rep, 18783, vol. 10(1). link> doi> full text>
  • Teoh JH, Thamizhchelvan AM, Davoodi P, Ramasamy S, Vijayavenkataraman S, Yang Q, Dicolandrea T, Zhao H, Fuh JYH, Liou Y-C, Wang C-H. 2019. Investigation of the application of a Taylor-Couette bioreactor in the post-processing of bioprinted human dermal tissue. BIOCHEMICAL ENGINEERING JOURNAL, Article ARTN 107317, vol. 151. link> doi>
  • Li Z, Lei IM, Davoodi P, Huleihel L, Huang YYS. 2019. Solution Formulation and Rheology for Fabricating Extracellular Matrix-Derived Fibers Using Low-Voltage Electrospinning Patterning. ACS Biomater Sci Eng, 3676-3684, vol. 5(7). link> doi>
  • Lei C, Davoodi P, Zhan W, Chow PK-H, Wang C-H. 2019. Development of Nanoparticles for Drug Delivery to Brain Tumor: The Effect of Surface Materials on Penetration Into Brain Tissue. J Pharm Sci, 1736-1745, vol. 108(5). link> doi>
  • Muthumariappan S, Ng WC, Adine C, Ng KK, Davoodi P, Wang C-H, Ferreira JN. 2019. Localized Delivery of Pilocarpine to Hypofunctional Salivary Glands through Electrospun Nanofiber Mats: An Ex Vivo and In Vivo Study. Int J Mol Sci, vol. 20(3). link> doi>
  • Yan W-C, Davoodi P, Vijayavenkataraman S, Tian Y, Ng WC, Fuh JYH, Robinson KS, Wang C-H. 2018. 3D bioprinting of skin tissue: From pre-processing to final product evaluation. Adv Drug Deliv Rev, 270-295, vol. 132. link> doi>
  • Davoodi P, Lee LY, Xu Q, Sunil V, Sun Y, Soh S, Wang C-H. 2018. Drug delivery systems for programmed and on-demand release. Adv Drug Deliv Rev, 104-138, vol. 132. link> doi>
  • Wang C-H, Xu XY, Zhan W, Davoodi P. 2018. 3D-Bioprinting and Micro-/Nano-Technology: Emerging Technologies in Biomedical Sciences. Adv Drug Deliv Rev, 1-2, vol. 132. link> doi>
  • Ong YXJ, Lee LY, Davoodi P, Wang C-H. 2018. Production of drug-releasing biodegradable microporous scaffold using a two-step micro-encapsulation/supercritical foaming process. JOURNAL OF SUPERCRITICAL FLUIDS, 263-269, vol. 133. link> doi>
  • Davoodi P, Ng WC, Srinivasan MP, Wang C-H. 2017. Codelivery of anti-cancer agents via double-walled polymeric microparticles/injectable hydrogel: A promising approach for treatment of triple negative breast cancer. Biotechnol Bioeng, 2931-2946, vol. 114(12). link> doi>
  • Cui Y-N, Xu Q-X, Davoodi P, Wang D-P, Wang C-H. 2017. Enhanced intracellular delivery and controlled drug release of magnetic PLGA nanoparticles modified with transferrin. Acta Pharmacol Sin, 943-953, vol. 38(6). link> doi>
  • Davoodi P, Srinivasan MP, Wang C-H. 2017. Effective co-delivery of nutlin-3a and p53 genes via core-shell microparticles for disruption of MDM2-p53 interaction and reactivation of p53 in hepatocellular carcinoma. J Mater Chem B, 5816-5834, vol. 5(29). link> doi>
  • Davoodi P, Ghoreishi SM, Hedayati A. 2017. Optimization of supercritical extraction of galegine from Galega officinalis L.: Neural network modeling and experimental optimization via response surface methodology. KOREAN JOURNAL OF CHEMICAL ENGINEERING, 854-865, vol. 34(3). link> doi>
  • Davoodi P, Ng WC, Yan WC, Srinivasan MP, Wang C-H. 2016. Double-Walled Microparticles-Embedded Self-Cross-Linked, Injectable, and Antibacterial Hydrogel for Controlled and Sustained Release of Chemotherapeutic Agents. ACS Appl Mater Interfaces, 22785-22800, vol. 8(35). link> doi>
  • Davoodi P, Srinivasan MP, Wang C-H. 2016. Synthesis of intracellular reduction-sensitive amphiphilic polyethyleneimine and poly(ε-caprolactone) graft copolymer for on-demand release of doxorubicin and p53 plasmid DNA. Acta Biomater, 79-93, vol. 39. link> doi>
  • Yan W-C, Davoodi P, Tong YW, Wang C-H. 2016. Computational study of core-shell droplet formation in coaxial electrohydrodynamic atomization process. AICHE JOURNAL, 4259-4276, vol. 62(12). link> doi>
  • Davoodi P, Feng F, Xu Q, Yan W-C, Tong YW, Srinivasan MP, Sharma VK, Wang C-H. 2015. Coaxial electrohydrodynamic atomization: microparticles for drug delivery applications. J Control Release, 70-82, vol. 205. link> doi>
  • Xie J, Jiang J, Davoodi P, Srinivasan MP, Wang C-H. 2015. Electrohydrodynamic atomization: A two-decade effort to produce and process micro-/nanoparticulate materials. Chem Eng Sci, 32-57, vol. 125. link> doi>

Other

  • Feng F, Neoh KY, Davoodi P, Wang C-H. 2017. Coaxial double-walled microspheres for combined release of cytochrome c and doxorubicin. JOURNAL OF CONTROLLED RELEASE (pp. E30-E31, vol. 259). link> doi>
Top 10 CUG Top 5 Guardian Athena SWAN