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    •
    Dr Jan-Herman Kuiper

    Dr Jan-Herman Kuiper

    Title
    Senior Lecturer in Biomechanics
    Location
    School of Pharmacy & Bioengineering, Keele University / The Robert Jones and Agnes Hunt Orthopaedic Hospital
    Role

    Research theme: Regenerative Medicine
    Contact me
    Via tel or email
    Phone
    +44 (0) 1691 404581
    Email
    j.h.kuiper@keele.ac.uk

    Biography

    ISTM_jhkuiper_equipment_190x271 Dr Jan-Herman Kuiper was appointed as a Lecturer in Biomechanics at Keele in 2001, but is based at the Robert Jones & Agnes Hunt Orthopaedic Hospital in Oswestry. His research training at MSc and PhD level was at the University of Twente and the University of Nijmegen in the Netherlands. He became a Senior Lecturer in 2017.

    He has extensive experience in the use of Finite Element-based computer models for design optimization, modelling of hydrated tissues and bone, and biological processes such as adaptive bone remodelling and fracture repair One of his long standing interests is the control of biological processes through mechanical conditions. Most of his work in this area is concentrated on the control of long bone fracture repair by movements at the fracture site, which he has investigated experimentally and theoretically. Findings from these studies have aided his clinical collaborators including Prof James Richardson and Prof Sally Roberts.

    Jan-Herman Kuiper's collaboration with other laboratory based scientists includes joint projects with Prof Alicia El Haj and Prof Ying Yang to control the response of bone cells (osteoblasts) to mechanical strains in order to improve bone formation on resorbable 3-dimensional scaffolds. These studies are supported by substantial joint grants from the Engineering & Physical Sciences Research Council and the European Commission Framework Programme. 

    In a collaboration with Dr Carol Evans at Manchester University, Dr Kuiper also receives funding from the AO Foundation in Switzerland to study the influence of fracture site movements on bone formation during limb lengthening.

    Other European collaboration includes European Commission Framework VI “New and Emerging Science and Technology” funding in partnership with several European researchers, including Dr Patrick Warnke at the University of Kiel in Germany who has pioneered a clinical procedure to grow a complete new jaw for a patient inside a back muscle. The objective of this new high risk/high benefit "MYJOINT" project is to develop a clinical procedure to grow a complete synovial joint in a patient’s back muscle, similar to the procedure pioneered by Dr Warnke. One of Dr Kuiper's specific tasks is to model the control of articular joint formation by mechanical conditions.  

    Summary of previous posts (with dates):

    • Lecturer in Biomechanics (Keele University, 2001-2017)
    • Post-graduate researcher (Robert Jones and Agnes Hunt Orthopaedic Hospital, 1997-2001)
    • Post-graduate researcher (Keele University, 1993-1997)
    • Research assistant (University of Nijmegen, 1992-1993)
    • Ph.D. student (University of Nijmegen, 1989-1992)
    • Research assistant (University of Nijmegen,1988-1989)

     

     

    Research and scholarship

    Research theme: 

    All my current work is related to orthopaedics and broadly characterised by two interests.

    1. Mechanical guidance of skeletal tissue formation.

    Mechanical influences on tissue formation and differentiation, in particular with relation to fracture healing and cartilage repair

    2 .Development and pre-clinical testing of joint replacement implants, bioresorbable orthopaedic devices and bone substitution products

    Examples are the development and testing of impaction grafting for hip and knee revision surgery, and the development and testing of knee ligament repair systems using a composite bioresorbable materials.

    Teaching

    Teaching responsibilities:

    1. Biomechanics module at MSc courses in Biomedical Engineering and Cell & Tissue Engineering, Keele University

    2. Tribology in Joint replacement Implants module at Orthopaedic Science Course, Oswestry

    3. Statistics module for postgraduate research students

    4. Regular contributions to Friday afternoon teaching sessions, Oswestry

    5. Supervision of BSc, MSc and MPhil-students who do placements and final-year projects. On average, seven students visit us yearly from Universities in The Netherlands, Germany and France.

    6. Co-supervision of PhD and MD students.

    Supervision of orthopaedic registrars doing biomechanical research.

    Further information

    Dr Kuiper is a reviewer for the EPSRC, several charities and several journals.

    He is a member of a Special Interest Group in IPEM (Institute of Physics and Engineering and Medicine), the American Society of Mechanical Engineers, the European Society of Biomechanics and the British Orthopaedic Research Society.

    Selected Publications

    • McCarthy HS, Tins B, Gallacher PD, Jermin P, Richardson JB, Kuiper JH, Roberts S. 2023. Histological and Radiological Assessment of Endogenously Generated Repair Tissue In Vivo Following a Chondral Harvest. Cartilage, 19476035221149523. link> doi> full text>
    • Snow M, Middleton L, Mehta S, Roberts A, Grey R, Richardson J, Kuiper JH, ACTIVE Consortium, Smith A, White S, Roberts S, Griffiths D, Mohammed A, Moholkar K, Ashraf T, Green M, Hutchinson J, Bhullar T, Chitnis S, Shaw A, van Niekerk L, Hui A, Drogset JO, Knutsen G, McNicholas M, Bowditch M, Johnson D, Turner P, Chugh S, Hunt N, Ali S, Palmer S, Perry A, Davidson A, Hill P, Deo S, Satish V, Radford M, Langstaff R, Houlihan-Burne D, Spicer D, Phaltankar P, Hegab A, Marsh D, Cannon S, Briggs T, Pollock R, Carrington R, Skinner J, Bentley G, Price A, Schranz P, Mandalia V, O'Brien S. 2023. A Randomized Trial of Autologous Chondrocyte Implantation Versus Alternative Forms of Surgical Cartilage Management in Patients With a Failed Primary Treatment for Chondral or Osteochondral Defects in the Knee. Am J Sports Med, 3635465221141907. link> doi> full text>
    • Makos A, Kuiper JH, Kehoe O, Amarasena R. 2022. Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors. Inflammopharmacology. link> doi> full text>
    • Emery N, Strachan K, Kulshrestha R, Kuiper JH, Willis T. 2022. Evaluating the Feasibility and Reliability of Remotely Delivering and Scoring the North Star Ambulatory Assessment in Ambulant Patients with Duchenne Muscular Dystrophy. Children (Basel), vol. 9(5). link> doi> full text>
    • Trivedi R, John J, Ghodke A, Trivedi J, Munigangaiah S, Dheerendra S, Balain B, Ockendon M, Kuiper J. 2022. Intrathecal morphine in combination with bupivacaine as pre-emptive analgesia in posterior lumbar fusion surgery: a retrospective cohort study. Journal of Orthopaedic Surgery and Research, Article 241, vol. 17(1). link> doi> link> full text>

    Full Publications Listshow

    Journal Articles

    • McCarthy HS, Tins B, Gallacher PD, Jermin P, Richardson JB, Kuiper JH, Roberts S. 2023. Histological and Radiological Assessment of Endogenously Generated Repair Tissue In Vivo Following a Chondral Harvest. Cartilage, 19476035221149523. link> doi> full text>
    • Snow M, Middleton L, Mehta S, Roberts A, Grey R, Richardson J, Kuiper JH, ACTIVE Consortium, Smith A, White S, Roberts S, Griffiths D, Mohammed A, Moholkar K, Ashraf T, Green M, Hutchinson J, Bhullar T, Chitnis S, Shaw A, van Niekerk L, Hui A, Drogset JO, Knutsen G, McNicholas M, Bowditch M, Johnson D, Turner P, Chugh S, Hunt N, Ali S, Palmer S, Perry A, Davidson A, Hill P, Deo S, Satish V, Radford M, Langstaff R, Houlihan-Burne D, Spicer D, Phaltankar P, Hegab A, Marsh D, Cannon S, Briggs T, Pollock R, Carrington R, Skinner J, Bentley G, Price A, Schranz P, Mandalia V, O'Brien S. 2023. A Randomized Trial of Autologous Chondrocyte Implantation Versus Alternative Forms of Surgical Cartilage Management in Patients With a Failed Primary Treatment for Chondral or Osteochondral Defects in the Knee. Am J Sports Med, 3635465221141907. link> doi> full text>
    • Makos A, Kuiper JH, Kehoe O, Amarasena R. 2022. Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors. Inflammopharmacology. link> doi> full text>
    • Emery N, Strachan K, Kulshrestha R, Kuiper JH, Willis T. 2022. Evaluating the Feasibility and Reliability of Remotely Delivering and Scoring the North Star Ambulatory Assessment in Ambulant Patients with Duchenne Muscular Dystrophy. Children (Basel), vol. 9(5). link> doi> full text>
    • Trivedi R, John J, Ghodke A, Trivedi J, Munigangaiah S, Dheerendra S, Balain B, Ockendon M, Kuiper J. 2022. Intrathecal morphine in combination with bupivacaine as pre-emptive analgesia in posterior lumbar fusion surgery: a retrospective cohort study. Journal of Orthopaedic Surgery and Research, Article 241, vol. 17(1). link> doi> link> full text>
    • Abas S, Kuiper JH, Roberts S, McCarthy H, Williams M, Bing A, Tins B, Makwana N. 2022. Osteochondral Lesions of the Ankle Treated with Bone Marrow Concentrate with Hyaluronan and Fibrin: A Single-Centre Study. Cells, vol. 11(4). link> doi> full text>
    • Heaver C, Pinches M, Kuiper JH, Thomas G, Lewthwaite S, Burston BJ, Banerjee RD. 2021. Greater trochanteric pain syndrome: focused shockwave therapy versus an ultrasound guided injection: a randomised control trial. Hip Int, 11207000211060396. link> doi>
    • Sharma N, Rehmatullah N, Kuiper JH, Gallacher P, Barnett AJ. 2021. Clinical validation of the Oswestry-Bristol Classification as part of a decision algorithm for trochlear dysplasia surgery. Bone Joint J, 1586-1594, vol. 103-B(10). link> doi>
    • Minshull C, Gallacher P, Roberts S, Barnett A, Kuiper JH, Bailey A. 2021. Contralateral strength training attenuates muscle performance loss following anterior cruciate ligament (ACL) reconstruction: a randomised-controlled trial. Eur J Appl Physiol, 3551-3559, vol. 121(12). link> doi> full text>
    • Hopkins T, Richardson J, Kuiper JH. 2021. Identifying Consensus and Open Questions around Assessing or Predicting the Quality and Success of Cartilage Repair: A Delphi Study. Surgeries, 286-302, vol. 2(3). link> doi> link> full text>
    • Hopkins T, Wright KT, Kuiper NJ, Roberts S, Jermin P, Gallacher P, Kuiper JH. 2021. An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans. Cells, vol. 10(8). link> doi> full text>
    • Amit P, Kuiper JH, James S, Snow M. 2021. Does statin-treated hyperlipidemia affect rotator cuff healing or muscle fatty infiltration after rotator cuff repair?. J Shoulder Elbow Surg, 2465-2474, vol. 30(11). link> doi> full text>
    • Sykes JG, Bailey A, Bing AJ, Kuiper NJ, Makwana N, Richardson J, Kuiper J-H. 2021. Design and psychometric testing of a new patient-reported outcome measure for ankle treatment. Foot (Edinb), 101793, vol. 49. link> doi>
    • Bahsoun S, Kuiper J-H, Hulme CH, Twigg AJA, El Masri W, Glass C, Soni B, Kumar N, Chowdhury JR, Osman A, Wright KT. 2021. Evaluating patient perspectives on participating in scientific research and clinical trials for the treatment of spinal cord injury. Sci Rep, 4361, vol. 11(1). link> doi> full text>
    • Garcia J, McCarthy HS, Kuiper JH, Melrose J, Roberts S. 2021. Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?. Biomolecules, vol. 11(1). link> doi> full text>
    • Wang J, Roberts S, Kuiper JH, Zhang W, Garcia J, Cui Z, Wright K. 2020. Characterization of regional meniscal cell and chondrocyte phenotypes and chondrogenic differentiation with histological analysis in osteoarthritic donor-matched tissues. Sci Rep, 21658, vol. 10(1). link> doi> full text>
    • Sajid S, Day E, Kuiper JH, Singh R, Pickard S. 2020. Biomechanical Evaluation Comparing Pulvertaft Weave and Side-to-Side Tenorrhaphy Using Porcine Tendons. The Journal of Hand Surgery (Asian-Pacific Volume), 447-452, vol. 25(4). link> doi> link> full text>
    • Nasello G, Vautrin A, Pitocchi J, Wesseling M, Kuiper JH, Pérez MÁ, García-Aznar JM. 2021. Mechano-driven regeneration predicts response variations in large animal model based on scaffold implantation site and individual mechano-sensitivity. Bone, 115769, vol. 144. link> doi> full text>
    • Sajid S, Kuiper JH, Dhawan R, Banerjee R, Lewthwaite S. 2020. Soft Tissue Radiological Knee (SToRK) Index: An observational cohort study to produce an index that quantifies the magnitude of soft tissue around the knee using standard radiographs. Journal of Clinical Orthopaedics and Trauma, S909-S915, vol. 11(Suppl 5). link> doi> link>
    • Sharma N, Brown A, Bouras T, Kuiper J, Eldridge J, Barnett A. 2020. THE OSWESTRY-BRISTOL CLASSIFICATION: A NEW CLASSIFICATION SYSTEM FOR TROCHLEAR DYSPLASIA. The Knee, S1-S2, vol. 27(S1). link> doi> link>
    • Dover C, Kuiper JH, Craig P, Shaylor P. 2020. Ten years on: increased metal ion levels in a cohort of patients who underwent uncemented metal-on-polyethylene total hip arthroplasty. Bone and Joint Journal, 832-837, vol. 102-B(7). link> doi> link>
    • Muellensiefen M, Tins B, Kuiper J-H, Weber M-A, Krakowski-Roosen H. 2020. Development of a total hip replacement phantom for the assessment of CT-image quality. Acta Radiologica. link> doi> link>
    • Kulshrestha R, Kuiper JH, Masri WE, Chowdhury JR, Kaur S, Kumar N, Lalam R, Osman AE. 2020. Scoliosis in paediatric onset spinal cord injuries. Spinal Cord. link> doi> link> full text>
    • Sharma N, Brown A, Bouras T, Kuiper JH, Eldridge J, Barnett A. 2020. The Oswestry-Bristol Classification. Bone Joint J, 102-107, vol. 102-B(1). link> doi> full text>
    • Thomas RL, Kuiper JH, Knight TP. 2020. Properties and Function of the Flexor Hallucis Capsularis Interphalangeus Tendon. Clin Anat, 689-695, vol. 33(5). link> doi> full text>
    • Bouras T, Kuiper JH, Barnett A. 2019. Isolated medial patellofemoral ligament reconstruction significantly improved quality of life in patients with recurrent patella dislocation: a response to Hiemstra et al.'s letter to the editor. Knee Surg Sports Traumatol Arthrosc, 3735-3737, vol. 27(11). link> doi> full text>
    • Campbell K, Naire S, Kuiper JH. 2019. A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - I: the effects of growth factors. J Tissue Eng, 2041731419827791, vol. 10. link> doi> full text>
    • Campbell K, Naire S, Kuiper JH. 2019. A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - II: the effects of co-implantation. J Tissue Eng, 2041731419827792, vol. 10. link> doi> full text>
    • Bhattacharjee A, Kuiper JH, Roberts S, Harrison PE, Cassar-Pullicino VN, Tins B, Bajada S, Richardson JB. 2019. Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells. J Orthop Res, 1303-1309, vol. 37(6). link> doi> full text>
    • Tins B and Kuiper JH. 2019. Building an orthopaedic CT phantom for under £50. Br J Radiol, 20180279, vol. 92(1094). link> doi>
    • Manoharan G, Singh R, Kuiper JH, Nokes LDM. 2018. Distal fibula oblique fracture fixation using one-third tubular plate with and without lag screw - A biomechanical study of stability. J Orthop, 549-552, vol. 15(2). link> doi>
    • Sykes JG, Kuiper JH, Richardson JB, Roberts S, Wright KT, Kuiper NJ. 2018. Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy. Eur Cell Mater, 255-267, vol. 35. link> doi> full text>
    • Chan SK, Bentick KR, Kuiper JH, Kelly CP. 2018. External rotation bracing for first-time anterior dislocation of the shoulder: A discontinued randomised controlled trial comparing external rotation bracing with conventional sling. Shoulder and Elbow, 256-264, vol. 11(4). link> doi>
    • White SH, Roberts S, Kuiper JH. 2018. The twin peg Oxford knee - Medium term survivorship and surgical principles. Knee, 314-322, vol. 25(2). link> doi> full text>
    • Thangaraj R, Kuiper J, Perkins RD. 2019. Low failure rate at short term for 40 mm heads and second generation triple annealed HCLPE liners in hybrid hip replacements. J Clin Orthop Trauma, 350-357, vol. 10(2). link> doi> full text>
    • Saweeres ESB, Kuiper JH, Evans RO, Richardson JB, White SH. 2005. Predicting in vivo clinical performance of anterior cruciate ligament fixation methods from in vitro analysis: industrial tests of fatigue life and tolerance limits are more useful than other cyclic loading parameters. Am J Sports Med, 666-673, vol. 33(5). link> doi>
    • Carmont MR, Kuiper JH, Grävare Silbernagel K, Karlsson J, Nilsson-Helander K. 2017. Tendon end separation with loading in an Achilles tendon repair model: comparison of non-absorbable vs. absorbable sutures. J Exp Orthop, 26, vol. 4(1). link> doi> full text>
    • Richardson JB, Wright KT, Wales J, Kuiper JH, McCarthy HS, Gallacher P, Harrison PE, Roberts S. 2017. Efficacy and safety of autologous cell therapies for knee cartilage defects (autologous stem cells, chondrocytes or the two): randomized controlled trial design. Regen Med, 493-501, vol. 12(5). link> doi> full text>
    • Wright KT, Kuiper JH, Richardson JB, Gallacher P, Roberts S. 2017. The Absence of Detectable ADAMTS-4 (Aggrecanase-1) Activity in Synovial Fluid Is a Predictive Indicator of Autologous Chondrocyte Implantation Success. Am J Sports Med, 1806-1814, vol. 45(8). link> doi> full text>
    • Naheed B, Kuiper JH, Uthman OA, O'Mahony F, O'Brien PMS. 2017. Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome. Cochrane Database Syst Rev, CD010503, vol. 3. link> doi> full text>
    • Mcfarlane J, Kuiper JH, Kiely N. 2016. Surgical treatment for developmental dysplasia of the hip- a single surgeon series of 47 hips with a 7 year mean follow up). Acta Orthop Belg, 754-761, vol. 82(4). link>
    • Adams CF, Dickson AW, Kuiper J-H, Chari DM. 2016. Nanoengineering neural stem cells on biomimetic substrates using magnetofection technology. Nanoscale, 17869-17880, vol. 8(41). link> doi> full text>
    • Ali M, Kuiper J, John J. 2016. Biomechanical analysis of tension band wiring (TBW) of transverse fractures of patella. Chin J Traumatol, 255-258, vol. 19(5). link> doi> full text>
    • Bailey CA, Kuiper JH, Kelly CP. 2006. Biomechanical evaluation of a new composite bioresorbable screw. J Hand Surg Br, 208-212, vol. 31(2). link> doi>
    • Mishra V, Kuiper JH, Kelly CP. 2003. Influence of core suture material and peripheral repair technique on the strength of Kessler flexor tendon repair. J Hand Surg Br, 357-362, vol. 28(4). link> doi>
    • Prendergast PJ, van Driel WD, Kuiper JH. 1996. A comparison of finite element codes for the solution of biphasic poroelastic problems. Proc Inst Mech Eng H, 131-136, vol. 210(2). link> doi>
    • Karlakki SL, Hamad AK, Whittall C, Graham NM, Banerjee RD, Kuiper JH. 2016. Incisional negative pressure wound therapy dressings (iNPWTd) in routine primary hip and knee arthroplasties: A randomised controlled trial. Bone Joint Res, 328-337, vol. 5(8). link> doi> full text>
    • Dugard MN, Kuiper JH, Parker J, Roberts S, Robinson E, Harrison P, Richardson JB. 2017. Development of a Tool to Predict Outcome of Autologous Chondrocyte Implantation. Cartilage, 119-130, vol. 8(2). link> doi> full text>
    • Garcia J, Wright K, Roberts S, Kuiper JH, Mangham C, Richardson J, Mennan C. 2016. Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus. Scientific Reports, Article ARTN 24295, vol. 6. link> doi> link> full text>
    • Bhattacharjee A, McCarthy HS, Tins B, Roberts S, Kuiper JH, Harrison PE, Richardson JB. 2016. Autologous Bone Plug Supplemented With Autologous Chondrocyte Implantation in Osteochondral Defects of the Knee. The American journal of sports medicine, 1249-1259, vol. 44(5). doi> full text>
    • Singh S, Kuiper JH, Behzadian A, Madhusudhan T, Sinha A. 2016. Alternative tension band technique for olecranon fractures: A biomechanical study. Injury, 294-295, vol. 47(2). doi> link>
    • Khan M, Kuiper JH, Sieniawska C, Richardson JB. 2016. Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty. J Orthop, 450-454, vol. 13(4). link> doi>
    • Aulakh TS, Jayasekera N, Singh R, Patel A, Roulahamin N, Kuiper JH, Richardson JB. 2015. Efficacy of hip resurfacing arthroplasty: 6 year results from an international multisurgeon prospective cohort study. Acta Orthop Belg, 197-208, vol. 81(2). link>
    • Kuiper JH. 2015. The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study. The Knee, 333-337, vol. 22(4). doi> link> full text>
    • Roberts S, Evans H, Wright K, van Niekerk L, Caterson B, Richardson JB, Kumar KHS, Kuiper JH. 2015. ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion. Osteoarthritis Cartilage, 1622-1626, vol. 23(9). link> doi> full text>
    • Walter MNM, Kohli N, Khan N, Major T, Fuller H, Wright KT, Kuiper J-H, Johnson WEB. 2015. Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability. J Stem Cells Regen Med, 18-24, vol. 11(1). link> doi> full text>
    • Naheed B, Uthman O, O'Mahony F, Kuiper JH, O'Brien P. 2014. Gonadotropin-releasing hormone (GnRH) analogues for premenstrual syndrome (PMS). Cochrane Database of Systematic Reviews. doi> link>
    • Deegan AJ, Aydin HM, Hu B, Konduru S, Kuiper JH, Yang Y. 2014. A facile in vitro model to study rapid mineralization in bone tissues. Biomed Eng Online, 136, vol. 13. link> doi> full text>
    • Aulakh TS, Jayasekera N, Singh R, Patel A, Kuiper JH, Richardson JB. 2014. Hip resurfacing arthroplasty: A new method to assess and quantify learning phase. Acta Orthop Belg, 397-402, vol. 80(3). link>
    • Cartwright A, Schmutz C, Askari A, Kuiper J-H, Middleton J. 2014. Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritis. Cytokine, 53-59, vol. 67(2). link> doi>
    • Maripuri SN, Gallacher PD, Bridgens J, Kuiper JH, Kiely NT. 2013. Ponseti casting for club foot - above- or below-knee?: A prospective randomised clinical trial. Bone Joint J, 1570-1574, vol. 95-B(11). link> doi>
    • Barlow D, Bansal R, Barlow T, Rhee SJ, Kuiper JH, Makwana NK. 2013. Effect of cotton padding on the setting properties of plaster slabs. Ann R Coll Surg Engl, 107-109, vol. 95(2). link> doi> full text>
    • Balain B, Jaiswal A, Trivedi JM, Eisenstein SM, Kuiper JH, Jaffray DC. 2013. The Oswestry Risk Index: an aid in the treatment of metastatic disease of the spine. Bone Joint J, 210-216, vol. 95-B(2). link> doi>
    • Miyazaki T, Uchida K, Sato M, Watanabe S, Yoshida A, Wada M, Shimada S, Kuiper JH, Baba H. 2012. Knee laxity after staircase exercise predicts radiographic disease progression in medial compartment knee osteoarthritis. Arthritis Rheum, 3908-3916, vol. 64(12). link> doi>
    • Johansson A, Kuiper J-H, Sundqvist T, Persson F, Speier C, D'Alfonso D, Richardson JB, Öberg Å. 2012. Spectroscopic measurement of cartilage thickness in arthroscopy: ex vivo validation in human knee condyles. Arthroscopy, 1513-1523, vol. 28(10). link> doi>
    • Hanifi A, Richardson JB, Kuiper JH, Roberts S, Pleshko N. 2012. Clinical outcome of autologous chondrocyte implantation is correlated with infrared spectroscopic imaging-derived parameters. Osteoarthritis Cartilage, 988-996, vol. 20(9). link> doi>
    • Balain B, Kerin C, Kanes G, Roberts SN, Rees D, Kuiper JH. 2012. Effects of knee compartment, concomitant surgery and smoking on medium-term outcome of microfracture. Knee, 440-444, vol. 19(4). link> doi>
    • Fricker RA, Kuiper JH, Gates MA. 2012. Transplanting intact donor tissue enhances dopamine cell survival and the predictability of motor improvements in a rat model of Parkinson's disease. PLoS One, e47169, vol. 7(10). link> doi> full text>
    • Lutianov M, Naire S, Roberts S, Kuiper J-H. 2011. A mathematical model of cartilage regeneration after cell therapy. J Theor Biol, 136-150, vol. 289. link> doi>
    • Jaiswal A, Gilbert RE, Sunil Kumar KH, Carrothers AD, Kuiper J-H, Richardson JB. 2011. Function and survival after revision of hip resurfacing. Hip Int, 610-615, vol. 21(5). link> doi>
    • Johansson A, Sundqvist T, Kuiper J-H, Öberg PÅ. 2011. A spectroscopic approach to imaging and quantification of cartilage lesions in human knee joints. Phys Med Biol, 1865-1878, vol. 56(6). link> doi>
    • Cheung G, Carmont MR, Bing AJF, Kuiper J-H, Alcock RJ, Graham NM. 2010. No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients. Acta Orthop Belg, 619-627, vol. 76(5). link> full text>
    • Aulakh TS, Kuiper JH, Dixey J, Richardson JB. 2011. Hip resurfacing for rheumatoid arthritis: independent assessment of 11-year results from an international register. Int Orthop, 803-808, vol. 35(6). link> doi>
    • Baas E, Kuiper JH, Yang Y, Wood MA, El Haj AJ. 2010. In vitro bone growth responds to local mechanical strain in three-dimensional polymer scaffolds. JOURNAL OF BIOMECHANICS, 733-739, vol. 43(4). link> doi>
    • Baas E, Kuiper JH, Yang Y, Wood MA, El Haj AJ. 2010. In vitro bone growth responds to local mechanical strain in three-dimensional polymer scaffolds. J Biomech, 733-739, vol. 43(4). link> doi>
    • Bhosale AM, Kuiper JH, Johnson WEB, Harrison PE, Richardson JB. 2009. Midterm to long-term longitudinal outcome of autologous chondrocyte implantation in the knee joint: a multilevel analysis. Am J Sports Med, 131S-138S, vol. 37 Suppl 1. link> doi>
    • Khan M, Kuiper J-H, Edwards D, Robinson E, Richardson JB. 2009. Birmingham hip arthroplasty: five to eight years of prospective multicenter results. J Arthroplasty, 1044-1050, vol. 24(7). link> doi>
    • Aulakh TS, Rao C, Kuiper J-H, Richardson JB. 2010. Hip resurfacing and osteonecrosis: results from an independent hip resurfacing register. Arch Orthop Trauma Surg, 841-845, vol. 130(7). link> doi>
    • Balain B, Ennis O, Kanes G, Singhal R, Roberts SNJ, Rees D, Kuiper JH. 2009. Response shift in self-reported functional scores after knee microfracture for full thickness cartilage lesions. Osteoarthritis Cartilage, 1009-1013, vol. 17(8). link> doi>
    • Malviya A, Kuiper JH, Makwana N, Laing P, Ashton B. 2009. The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study. J Orthop Surg Res, 17, vol. 4. link> doi> full text>
    • Aulakh TS, Jayasekera N, Kuiper J-H, Richardson JB. 2009. Long-term clinical outcomes following the use of synthetic hydroxyapatite and bone graft in impaction in revision hip arthroplasty. Biomaterials, 1732-1738, vol. 30(9). link> doi>
    • Rethnam U, Kuiper J, Makwana N. 2009. Biomechanical characteristics of three staples commonly used in foot surgery. Journal of Foot and Ankle Research, Article 5, vol. 2. doi> link>
    • John J, Kuiper JH, May PC. 2009. Age at follow-up and mechanical axis are good predictors of function after unicompartmental knee arthroplasty. An analysis of patients over 17 years follow-up. Acta Orthop Belg, 45-50, vol. 75(1). link> full text>
    • Toms AD, Barker RL, McClelland D, Chua L, Spencer-Jones R, Kuiper J-H. 2009. Repair of defects and containment in revision total knee replacement: a comparative biomechanical analysis. J Bone Joint Surg Br, 271-277, vol. 91(2). link> doi>
    • Khan M, Kuiper J-H, Richardson JB. 2008. The exercise-related rise in plasma cobalt levels after metal-on-metal hip resurfacing arthroplasty. J Bone Joint Surg Br, 1152-1157, vol. 90(9). link> doi>
    • Gokhale S, Khan M, Kuiper J-H, Richardson JB, Davies JP. 2008. An arthroscopic hip documentation form. Arthroscopy, 839-842, vol. 24(7). link> doi>
    • John J, Kuiper JH, Kelly CP. 2008. Learning assessment at shoulder surgical skills course. Ann R Coll Surg Engl, 120-122, vol. 90(2). link> doi>
    • Baas E and Kuiper JH. 2008. A numerical model of heterogeneous surface strains in polymer scaffolds. J Biomech, 1374-1378, vol. 41(6). link> doi>
    • Wood MA, Yang Y, Baas E, Meredith DO, Richards RG, Kuiper JH, El Haj AJ. 2008. Correlating cell morphology and osteoid mineralization relative to strain profile for bone tissue engineering applications. J R Soc Interface, 899-907, vol. 5(25). link> doi>
    • Khan M, Kuiper JH, Richardson JB. 2007. Can cobalt levels estimate in-vivo wear of metal-on-metal bearings used in hip arthroplasty?. Proc Inst Mech Eng H, 929-942, vol. 221(8). link> doi>
    • Aulakh TS, Robinson EV, Kuiper JH, Richardson JB. 2007. Multilevel analysis: A novel approach for statistical analysis of longitudinal studies in orthopaedics. VALUE IN HEALTH, A252-A253, vol. 10(6). link> doi>
    • García-Aznar JM, Kuiper JH, Gómez-Benito MJ, Doblaré M, Richardson JB. 2007. Computational simulation of fracture healing: influence of interfragmentary movement on the callus growth. J Biomech, 1467-1476, vol. 40(7). link> doi>
    • Kakarala G, Toms AD, Kuiper J-H. 2006. Stereolithographic models for biomechanical testing. Knee, 451-454, vol. 13(6). link> doi>
    • John J, Wagner WW, Kuiper JH. 2007. Tension-band wiring of transverse fractures of patella. The effect of site of wire twists and orientation of stainless steel wire loop: a biomechanical investigation. Int Orthop, 703-707, vol. 31(5). link> doi>
    • Oakley J and Kuiper JH. 2006. Factors affecting the cohesion of impaction bone graft. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 828-831, vol. 88B(6). link> doi>
    • KUIPER JH and Oakley J. 2006. Factors affecting the cohesion of impaction bone graft. Journal of Bone and Joint Surgery - British Volume, 828-831, vol. 88-B(6). doi>
    • Barker R, Takahashi T, Toms A, Gregson P, Kuiper JH. 2006. Reconstruction of femoral defects in revision hip surgery. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 832-836, vol. 88B(6). link> doi>
    • KUIPER JH, Barker R, Takahashi T, Toms A. 2006. Reconstruction of femoral defects in revision hip surgery: risk of fracture and stem migration after impaction bone grafting. Journal of Bone and Joint Surgery - British Volume, 832-836, vol. 88. doi>
    • RICHARDSON JB, Khan M, Kuiper JH, Takahashi T. 2006. Current in vivo wear of metal-on-metal bearings assessed by exercise-related rise in plasma cobalt level. Journal of Orthopaedic Research, 1657, vol. 24(11). doi>
    • Tselentakis G, Owen PJ, Naqui SZ, Kuiper JH, Richardson JB. 2006. Stiffness measurements to assess healing in bone transport: a preliminary report. Journal of Orthopaedics and Traumatology, 84-87, vol. 7.
    • Taylor D and Kuiper JH. 2001. The prediction of stress fractures using a 'stressed volume' concept. J Orthop Res, 919-926, vol. 19(5). link> doi>
    • Gómez-Benito MJ, García-Aznar JM, Kuiper JH, Doblaré M. 2006. A 3D computational simulation of fracture callus formation: influence of the stiffness of the external fixator. J Biomech Eng, 290-299, vol. 128(3). link> doi>
    • Gómez-Benito MJ, García-Aznar JM, Kuiper JH, Doblaré M. 2005. Influence of fracture gap size on the pattern of long bone healing: a computational study. J Theor Biol, 105-119, vol. 235(1). link> doi>
    • Toms AD, McClelland D, Chua L, Malefit MD, Verdonschot N, Jones RS, Kuiper JH. 2005. Mechanical testing of impaction bone grafting in the tibia. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 656-663, vol. 87B(5). link> doi>
    • Toms AD, McClelland D, Chua L, de Waal Malefijt M, Verdonschot N, Spencer Jones R, Kuiper J-H. 2005. Mechanical testing of impaction bone grafting in the tibia: initial stability and design of the stem. J Bone Joint Surg Br, 656-663, vol. 87(5). link> doi>
    • Gokhale S, Soliman A, Dantas JP, Richardson JB, Cook F, Kuiper J-H, Jones P. 2005. Variables affecting initial stability of impaction grafting for hip revision. Clin Orthop Relat Res, 174-180. link> doi>
    • Toms AD, Barker RL, Jones RS, Kuiper JH. 2004. Current concepts review - Impaction bone-grafting in revision joint replacement surgery. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2050-2060, vol. 86A(9). link> doi>
    • Toms AD, Barker RL, Jones RS, Kuiper JH. 2004. Impaction bone-grafting in revision joint replacement surgery. J Bone Joint Surg Am, 2050-2060, vol. 86(9). link> doi>
    • Tselentakis G, Kitano M, Owen PJ, Kuiper JH, Richardson JB, Evans GA. 2003. The behaviour of the periosteum during callotasis. J Pediatr Orthop B, 277-283, vol. 12(4). link> doi>
    • Saweeres EBS and Kuiper JH. 2003. Untitled. AMERICAN JOURNAL OF SPORTS MEDICINE, 325-326, vol. 31(2). link>
    • Saweeres ESB and Kuiper JH. 2003. Fatigue testing of some orthopaedic fixation devices. Am J Sports Med, 325-326, vol. 31(2). link>
    • Saweeres EB and Kuiper JH. 2003. Letter. The American journal of sports medicine, 525-527, vol. 31(2).
    • Saweeres ESB and Kuiper JH. 2003. Untitled (vol 31, pg 325, 2003). AMERICAN JOURNAL OF SPORTS MEDICINE, 814, vol. 31(5). link>
    • Tselentakis G, Owen PJ, Richardson JB, Kuiper JH, Haddaway MJ, Dwyer JS, Evans GA. 2001. Fracture stiffness in callotasis determined by dual-energy X-ray absorptiometry scanning. J Pediatr Orthop B, 248-254, vol. 10(3). link> doi>
    • Thompson MS, Dawson T, Kuiper JH, Northmore-Ball MD, Tanner KE. 2000. Acetabular morphology and resurfacing design. J Biomech, 1645-1653, vol. 33(12). link> doi>
    • Wade RH, New AM, Tselentakis G, Kuiper JH, Roberts A, Richardson JB. 1999. Malunion in the lower limb. A nomogram to predict the effects of osteotomy. J Bone Joint Surg Br, 312-316, vol. 81(2). link> doi>
    • Kuiper JH and Huiskes R. 1997. The predictive value of stress shielding for quantification of adaptive bone resorption around hip replacements. J Biomech Eng, 228-231, vol. 119(3). link> doi>
    • Kuiper JH and Huiskes R. 1997. Mathematical optimization of elastic properties: application to cementless hip stem design. J Biomech Eng, 166-174, vol. 119(2). link> doi>
    • Prendergast PJ, vanDriel WD, Kuiper JH. 1997. A comparison of finite element codes for the solution of biphasic poroelastic problems. PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 209-211, vol. 211(2). link>
    • Dwyer JS, Owen PJ, Evans GA, Kuiper JH, Richardson JB. 1996. Stiffness measurements to assess healing during leg lengthening. A preliminary report. J Bone Joint Surg Br, 286-289, vol. 78(2). link> doi>
    • Kuiper JH and Huiskes R. 1996. Friction and stem stiffness affect dynamic interface motion in total hip replacement. J Orthop Res, 36-43, vol. 14(1). link> doi>
    • RICHARDSON JB, GARDNER TN, HARDY JRW, EVANS M, KUIPER JH, KENWRIGHT J. 1995. DYNAMIZATION OF TIBIAL FRACTURES (VOL 77, PG 412, 1995). JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 985, vol. 77B(6). link>
    • Richardson JB, Gardner TN, Hardy JR, Evans M, Kuiper JH, Kenwright J. 1995. Dynamisation of tibial fractures. J Bone Joint Surg Br, 412-416, vol. 77(3). link> doi>
    • Meijer HJ, Kuiper JH, Starmans FJ, Bosman F. 1992. Stress distribution around dental implants: influence of superstructure, length of implants, and height of mandible. J Prosthet Dent, 96-102, vol. 68(1). link> doi>
    • Blankevoort L, Kuiper JH, Huiskes R, Grootenboer HJ. 1991. Articular contact in a three-dimensional model of the knee. J Biomech, 1019-1031, vol. 24(11). link> doi>

    Other

    • McCarthy HS, Garcia J, Gallacher P, Jermin P, Tins B, Richardson JB, Kuiper JH, Roberts S. 2019. The natural repair of articular cartilage in humans: an immunohistological study. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (pp. A26-A27, vol. 100). link>
    • Sykes JG, Kuiper J, Richardson JB, Wright KT, Kuiper NJ. 2018. IMPACT OF HUMAN PLATELET LYSATE ON THE EXPANSION AND CHONDROGENIC CAPACITY OF CULTURED HUMAN CHONDROCYTES FOR CARTILAGE CELL THERAPY. OSTEOARTHRITIS AND CARTILAGE (p. S103, vol. 26). link> doi>
    • Kuiper JH, Dugard N, Parker J, Harrison P, Kuiper CG, Roberts S, Richardson JB. 2018. MODELLING AND PREDICTING THE LONG-TERM CLINICAL OUTCOME OF AUTOLOGOUS CHONDROCYTE IMPLANTATION. OSTEOARTHRITIS AND CARTILAGE (pp. S145-S146, vol. 26). link> doi>
    • Garcia J, Hulme CH, Roberts S, Richardson JB, Kuiper JH, Wright KT. 2017. Similar phenotypes of cells in the repair tissues following microfracture or autologous chondrocyte implantation. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (p. A23, vol. 98). link>
    • Wright KT, Wilson E, Hulme C, Kuiper JH, Gallacher P, Richardson JB, Roberts S. 2016. Cartilage harvest elevates sCD14 and MMP-3 in the synovial fluid of the autologous chondrocyte implantation (ACI) treated joint. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (p. A24, vol. 97). link>
    • Naheed B, Kuiper JH, O'Brien S. 2016. A systematic review - ovarian suppression with GnRH analogues for management of PMS. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (p. 186, vol. 123). link>
    • Hampson K, Kuiper JH, El Haj AJ. 2008. The validation of a novel compression bioreactor to ensure the accurate application of loading regimes. TISSUE ENGINEERING PART A (p. 919, vol. 14). link>
    • Bajada S, Harrison P, Kuiper JH, Balbouzis T, Ashton BA, Cassar PV, Ashammakhi N, Richardson JB. 2007. Clinical trial of bone marrow stromal stem cell implantation for refractory fracture non-union: Results from the first patients. TISSUE ENGINEERING (p. 1657, vol. 13). link>
    • Oakley J and Kuiper JH. 2006. Factors affecting the cohesion of impaction bone graft. JOURNAL OF BONE AND MINERAL RESEARCH (p. 1161, vol. 21). link>
    • Bhosale A, Harrison P, Ashton B, Kuiper JH, Davies J, Roberts S, McCall I, Richardson J, Robinson E. 2006. Autologous chondrocyte implantation: 2-to-9 year OsCell experience. TISSUE ENGINEERING (p. 1022, vol. 12). link>
    • Richardson JB, Balbouzis T, Cassar-Pullicino V, Kuiper JH, Harrison PE, Bhosale A, Cook F, Haddaway MJ, Ashton B. 2006. Clinical application of adult bone marrow mesenchymal stem cells for treatment of fracture nonunions. TISSUE ENGINEERING (p. 1023, vol. 12). link>
    • Kuiper JH, Li F, Khan SA, Evans CE. 2006. Dynamic measurement system of interfragmentary movements in patients treated with ilizarov external fixation. BONE (p. S10, vol. 38). link> doi>
    • Hazlehurst ZV, Kitano M, Kuiper JH, Richardson JB, Ashton BA. 1998. The effect of fluid shear stress on osteoblast precursor cells. Biochem Soc Trans (p. S24, vol. 26). link> doi>
    • New AMR, Kloss M, Northmore-Ball MD, Kuiper JH, Tanner KE, Veldkamp E. 1998. Dynamic mechanical testing of prosthetic acetabular components. EXPERIMENTAL MECHANICS, VOLS 1 AND 2 (pp. 839-844). link>
    • KUIPER JH and HUISKES R. 1992. NUMERICAL OPTIMIZATION OF HIP-PROSTHETIC STEM MATERIAL. RECENT ADVANCES IN COMPUTER METHODS IN BIOMECHANICS & BIOMEDICAL ENGINEERING (pp. 76-84). link>

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