Biography
Ying completed her PhD at Manchester University in Materials Science and Technology in 1994. Before that, she obtained a BSc in Chemistry Engineering and a MSc in Polymer Science and Technology in Hunan University in 1981 and 1987 respectively. Between 1995 and 1997, she took up a postdoctoral research fellow in Tokyo Institute of Technology working on engineering polymer blends aiming to develop new automobile industrial materials. In the late 1997, Ying took a research associate position in Keele University and started her materials research in the medical field. Ying was appointed as a lecturer in Biomaterials and Tissue engineering in 2001 and promoted to senior lecturer in 2006 and reader in 2009. In December 2015, Ying was appointed as a chair and professor in Biomaterials and Tissue engineering.
Inaugural Lecture 3 July 2017 available on YouTube: https://www.youtube.com/watch?v=7LjN-hLJyZI&feature=youtu.be
Research and scholarship
Group Lead for Materials for Bioscience research group
and active member of Regenerative Medicine FReT & Orthopaedics & Biomechanics research group
Ying's current research has been focused on the application of engineering strategies in translational medicine. Great effort has been made to establish systematic study methods in utilizing smart/unique materials that trigger and detect specific cellular responses and application of non-destructive monitoring modalities for complicate cellular systems. The research includes smart nanofiber design and applications, detection of variation of cell adhesion capacities, developing immunemodulating materials, exploring unique techniques to detect heterogeneous cellular populations and correlating the structures of collagen based matrices to diseases. A few clinical relevant projects are being undertaken in relation to different tissues and organs, from colony growth of stem cells for cell therapy, rapid bone formation, osteogenic potency assay, pathological calcification of heart valves, the relation of pelvic organ prolapse and ageing. Ying's regeneration medicine research is centralized on bone, cartilage, blood vessel, cornea, retina, pseudoislets, skin, nerve generation and characterization.
THE ON-GOING PROJECTS INCLUDING:
• Establishment of 3D ARVC model from iPSC-CM cells
• Development/translation of xeno-free, nanofiber-based scaffold/actuator for human pluripotent stem cell expansion, differentiation, and implantation
• Replication and investigation of limbal stem cell niches
• Correlating the degradation in biomaterials and the associated immune response in macrophages by multimodal non-invasive imaging techniques
• Fabricating and characterization of fully functional blood vessel for homeostatic and vascular disease study
• Development of smart surface modification techniques with anti-biofilm, anti-fouling functions
• Separation and characterization of the progenitor cells in cardiac cell mixture
• Exploring novel nanofabrication protocols as matrix for iPSC-CM maturation
• Development of better pseudoislet model for diabetes treatment
• Investigation of relation of ageing and connective tissue disorder including prolapse, preterm premature rupture of membranes
• Development implantable 3D neuron circuits for treatment of disorder in CNS
• Application of FTIR techniques as diagnostic and characterization tool for disease and regenerative tissues
• Establishment of novel non-destructive optical modalities (OCT, Raman spectroscopy, microindentation) for tissue regeneration applications
Teaching
MSc courses in
- Cell & Tissue Engineering
- Biomedical Engineering
MTE-40036 Biomaterials, module leader
MTE-40024 Human Anatomy and Physiology, module leader
MTE-40033 Cell and Tissue Engineering, contributor
MTE-40034 Cell Biomechanics, contributor
MTE-40022 Bioreactor and Growth Environment, contributor
MTE-30002 Introduction of Biomedical Engineering, module leader
Coordinator: 3+1+1 programme with Guangzhou University
Supervising final year student projects in Life Science, Medicine and MSc projects
Further information
University Duties
- Programme director of master course, Biomedical Engineering, 2008-2014, 2019 to present
- Member of faculty postgraduate committee, 2019- present
- Deputy lead of Faculty Regenerative Medicine theme
- Group lead of Materials for Biomedicine in PhaB
- Chair of Postgraduate Medical School Safety Committee 2006-2015
- Departmental COSHH Officer in Postgraduate Medical School 2004 - 2017
- Departmental Laser Safety Adviser in Postgraduate Medical School 2004 - present
- Departmental Radiation Safety Adviser in Postgraduate Medical School 2004 - present
Membership of Professional Associations
- Member of European Biomaterials Society
- Member of European TERMIS
- 2003-2006 Member of IPEM (SIG)
- 2005-present member of SPIE
- 2006-present EPSRC College membership
BOOKS
- Li J, Yang Y, Gu K, Dong G. (Eds.). 2004. Biological micro- and nanotribology – Nature’s solutions. China Machine Press, Beijing, China.
- Yang Y, Yuan CQ, Li J, Gu KL, Hu B. (Eds.) (2008) Nanoscale technology in biological systems, (edited and translated from English to Chinese, original authors: Greco RS, Prinz FB, Smith RL), pp. 1-485, China Machine Press, Beijing.
Selected Publications
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In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants─Systematic Review and Meta-Analysis. ACS Biomater Sci Eng, 1749-1762, vol. 8(5). link> doi> full text>2022.
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New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. Sci Rep, 5109, vol. 12(1). link> doi> full text>2022.
- 2022.
- 2022.
- 2021.
Full Publications Listshow
Books
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Li J, Yang Y, Gu K, Dong G (Eds.). 2004. Biological micro- and nanotribology - Nature?s solutions. China Machine Press, Beijing, China.
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Ashammaki N and Waris T (Eds.). 2004. Enhancement of mechanical signals for tissue engineering bone. e-book, ..
Journal Articles
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Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation. Platelets, 2153823, vol. 34(1). link> doi> full text>2023.
- 2022.
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In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants─Systematic Review and Meta-Analysis. ACS Biomater Sci Eng, 1749-1762, vol. 8(5). link> doi> full text>2022.
- 2022.
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New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties. Sci Rep, 5109, vol. 12(1). link> doi> full text>2022.
- 2022.
- 2022.
- 2022.
- 2022.
- 2021.
- 2021.
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The Combination of Tissue-Engineered Blood Vessel Constructs and Parallel Flow Chamber Provides a Potential Alternative to In Vivo Drug Testing Models. Pharmaceutics, vol. 13(3). link> doi> full text>2021.
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Quantitative measurement of mechanical properties in wound healing processes in a corneal stroma model by using vibrational optical coherence elastography (OCE). Biomed Opt Express, 588-603, vol. 12(1). link> doi> full text>2021.
- 2020.
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Synthesis of magnetic nanoparticles with an IDA or TED modified surface for purification and immobilization of poly-histidine tagged proteins. RSC Adv, 11524-11534, vol. 10(19). link> doi> full text>2020.
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Bioactive silver phosphate/polyindole nanocomposites. RSC Adv, 11060-11073, vol. 10(19). link> doi> full text>2020.
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Biomedical Applications of Wrinkling Polymers. Recent Progress in Materials, 1-31, vol. 2(1). doi> link> full text>2020.
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Development and evaluation of cationic nanostructured lipid carriers for ophthalmic drug delivery of besifloxacin. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, Article ARTN 101496, vol. 55. link> doi> full text>2020.
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Cardiac Progenitor Cells from Stem Cells: Learning from Genetics and Biomaterials. Cells, vol. 8(12). link> doi> full text>2019.
- 2019.
- 2021.
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Regulation of endothelial cell arrangements within hMSC - HUVEC co-cultured aggregates. Biomed J, 166-177, vol. 42(3). link> doi> full text>2019.
- 2019.
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Dynamic Culture Substrates That Mimic the Topography of the Epidermal-Dermal Junction. Tissue Engineering: Part A, 214-223, vol. 25(3-4). link> doi> link> full text>2019.
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Investigation of Conjunctival Fibrosis Response Using a 3D Glaucoma Tenon's Capsule + Conjunctival Model. Invest Ophthalmol Vis Sci, 605-614, vol. 60(2). link> doi> full text>2019.
- 2018.
- 2018.
- 2018.
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The effects of biomimetically conjugated VEGF on osteogenesis and angiogenesis of MSCs (human and rat) and HUVECs co-culture models. Colloids Surf B Biointerfaces, 550-559, vol. 167. link> doi> full text>2018.
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Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study. Int J Mol Sci, vol. 19(3). link> doi> full text>2018.
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Investigation of the antibiofilm capacity of peptide-modified stainless steel. R Soc Open Sci, 172165, vol. 5(3). link> doi> full text>2018.
- 2018.
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Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy. Methods, 126-133, vol. 136. link> doi> full text>2018.
- 2017.
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Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy. Med Hypotheses, 84-87, vol. 109. link> doi> full text>2017.
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Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production. Histochem Cell Biol, 625-638, vol. 148(6). link> doi> full text>2017.
- 2017.
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Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. Eur J Obstet Gynecol Reprod Biol, 78-85, vol. 214. link> doi> full text>2017.
- 2017.
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Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition. Tissue Eng Part C Methods, 228-236, vol. 23(4). link> doi> full text>2017.
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Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation. Front Bioeng Biotechnol, 6, vol. 5. link> doi> full text>2017.
- 2016.
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Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015. Regen Med, 483-492, vol. 11(5). link> doi> full text>2016.
- 2016.
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A comparative study of skin cell activities in collagen and fibrin constructs. Med Eng Phys, 854-861, vol. 38(9). link> doi> full text>2016.
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Accelerating and increasing nano-scaled pore formation on electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) fibers. Journal of biomaterials science. Polymer edition, 1155-1169, vol. 27(11). doi> link> full text>2016.
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Correction: Optofluidic lens with low spherical and low field curvature aberrations. Lab On a Chip: microfluidic and nanotechnologies for chemistry, biology, and bioengineering. doi>2016.
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Fluorescent, online monitoring of PLGA degradation for regenerative medicine applications. RSC ADVANCES, 44364-44370, vol. 6(50). link> doi> full text>2016.
- 2015.
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Self-renewal of human embryonic stem cells on defined synthetic electrospun nanofibers. Biomed Mater, 065017, vol. 10(6). link> doi> full text>2015.
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9 - Image analysis and quantification of tissue scaffolds. Characterisation and Design of Tissue Scaffolds, 201-223. doi>2015.
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First results of LHCD experiments with 4.6 GHz system toward steady-state plasma in EAST. Nuclear Fusion. doi>2015.
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Nanofibrous scaffolds supporting optimal central nervous system regeneration: an evidence-based review. Journal of Neurorestoratology, 123-131, vol. 2015(3). doi> full text>2015.
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Preparation and analysis of a new bioorganic metallic material. RSC ADVANCES, 78030-78037, vol. 5(95). link> doi> full text>2015.
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In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow. J Neurointerv Surg, 969-972, vol. 8(9). link> doi> full text>2016.
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Nano-colloid printing of functionalized PLA-b-PEO copolymers: tailoring the surface pattern of adhesive motif and its effect on cell attachment. Physiol Res, S61-S73, vol. 64(Suppl 1). link> doi> full text>2015.
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Freezeout concept and dynamical transport model in intermediate-energy heavy-ion reactions. Physical Review C: Nuclear Physics, vol. 92(1). doi>2015.
- 2015.
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Validating A 3D tissue-engineered human blood vessel model for use as a novel model system for the assessment of thrombus formation. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 110-111, vol. 13. link>2015.
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Efficient alignment of primary CNS neurites using structurally engineered surfaces and biochemical cues. RSC ADVANCES, 22053-22059, vol. 5(28). link> doi> full text>2015.
- 2015.
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Molecular hydrogen emission in the interstellar medium of the Large Magellanic Cloud. MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 2490-2504, vol. 446(3). link> doi> full text>2015.
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A facile in vitro model to study rapid mineralization in bone tissues. Biomed Eng Online, 136, vol. 13. link> doi> full text>2014.
- 2014.
- 2014.
- 2014.
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Development of a stereotaxic device for low impact implantation of neural constructs or pieces of neural tissues into the mammalian brain. Biomed Res Int, 651236, vol. 2014. link> doi> full text>2014.
- 2014.
- 2014.
- 2014.
- 2013.
- 2013.
- 2013.
- 2013.
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αV β5 and CD44 are oxygen-regulated human embryonic stem cell attachment factors. Biomed Res Int, 729281, vol. 2013. link> doi> full text>2013.
- 2012.
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Control of scar tissue formation in the cornea: strategies in clinical and corneal tissue engineering. J Funct Biomater, 642-687, vol. 3(3). link> doi> full text>2012.
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Development of 3D co-culture of aligned glial cells in nanofibre scaffolds for implantation into neural injury sites. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 88-89, vol. 6. link>2012.
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Dictation of cell orientation throughout three dimensional hydrogels. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 386, vol. 6. link>2012.
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Ingrowth of bone cells within cryogels under compression and perfusion. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 241, vol. 6. link>2012.
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Regulation of genotype and phenotype of corneal stromal cells. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 137-138, vol. 6. link>2012.
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Study of adsorbed proteins on nanofibrous substrates. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 210, vol. 6. link>2012.
- 2012.
- 2012.
- 2012.
- 2013.
- 2011.
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REGULATION AND CHARACTERISATION OF CORNEAL STROMAL CELL CONTRACTION. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 694, vol. 34(8). link>2011.
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THE STUDY OF OPTICAL PROPERTIES AND PROTEOGLYCAN CONTENT OF NATIVE AND TISSUE ENGINEERING TENDONS BY PS-OCT. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 641, vol. 34(8). link>2011.
- 2012.
- 2011.
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Study of tissue engineered bone nodules by Fourier transform infrared spectroscopy. Analyst, 775-780, vol. 4. doi>2011.
- 2011.
- 2011.
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3D ingrowth of bovine articular chondrocytes in biodegradable cryogel scaffolds for cartilage tissue engineering. J Tissue Eng Regen Med. doi>2010.
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Vibrational spectroscopy differentiates between multipotent and pluripotent stem cells. Analyst. doi>2010.
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Influence of Cell and Collagen Concentration on the Cell-Matrix Mechanical Relationship in a Corneal Stroma Wound Healing Model. Exp Eye Res. doi>2010.
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In-depth imaging and quantification of degenerative changes associated with Achilles ruptured tendons by polarization-sensitive optical coherence tomography. Phys Med Biol, 3777-3787, vol. 55(13). doi>2010.
- 2010.
- 2010.
- 2010.
- 2010.
- 2010.
- 2010.
- 2010.
- 2009.
- 2009.
- 2004.
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Spectroscopic signatures of single, isolated cancer cell nuclei using synchrotron infrared microscopy. Analyst, 1176-1181, vol. 134.2009.
- 2009.
- 2009.
- 2008.
- 2008.
- 2009.
- 2008.
- 2008.
- 2008.
- 2008.
- 2008.
- 2007.
- 2007.
- 2007.
- 2007.
- 2007.
- 2006.
- 2006.
- 2006.
- 2006.
- 2006.
- 2006.
- 2005.
- 2005.
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Sensitivity of single, in vitro growing lung cancer cells to gemcitabine measured with synchrotron based fourier transform infrared microspectroscopy. EJC SUPPLEMENTS, 51, vol. 3(2). link>2005.
- 2005.
- 2005.
- 2005.
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Ultrahigh-resolution optical imaging of cellular structures of high-scattering biological tissues with whole-field optical coherence microcopy. SPIE, 39-43, vol. 5690. doi>2005.
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A New Technique for Mechanically Characterising Hydrogels for Tissue Engineering Cornea. Investigative Ophthalmology Visual Science, 2185, vol. 46.2005.
- 2005.
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Monitoring of lung tumour cell growth in artificial membranes. Biosens Bioelectron, 442-447, vol. 20(3). doi>2004.
- 2004.
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Optical coherence tomography imaging of structural components of the respiratory tract. Proceedings of SPIE. doi>2004.
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Use of OCT to study tumor cell growth in 3D membranes. Proceedings of SPIE. doi>2004.
- 2004.
- 2004.
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Bone tissue engineering. Scope, 33-35, vol. 13(3).2004.
- 2004.
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Mechanotransduction of bone cells in vitro; mechanobiology of bone tissue. Med Biol Eng Comput, 14-21, vol. 42(1). doi>2004.
- 2003.
- 2003.
- 2002.
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Development of a mechno responsive scaffold for tissue engineering. Biomaterials.2002.
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Reactive processing of acrylic–polyurea interpenetrating networks: reaction kinetic studies. Polymer International, 1035-1045, vol. 50(9). doi>2001.
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Blended lithium ion conducting polymer electrolytes based on boroxine polymers. Solid State Ionic, 353-359, vol. 140(3-4). doi>2001.
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High resolution optical tomographic imaging of biological tissues. Scope, 12-14, vol. 10.2001.
- 2000.
- 2000.
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Study of lung cancer cells by Fourier Transform Infrared spectroscopy. THORAX, A83, vol. 54. link>1999.
Other
- 2022.
- 2022.
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Proceedings of International Conference on Biomedical Engineering. Journal of Physics : Conference Series (vol. 2071). Institute of Physics (IoP). doi> link> full text>2021.
- 2019.
- 2019.
- 2019.
- 2019.
- 2019.
- 2019.
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Influence of catheter position on collateral flow during mechanical thrombectomy within an in vitro model of the anterior circulation. INTERNATIONAL JOURNAL OF STROKE (p. 22, vol. 13). link>2018.
- 2018.
- 2018.
- 2017.
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Online Monitoring Of Mechanical Properties Of 3D Tissue Engineered Constructs For Quality Assessment. TISSUE ENGINEERING PART A (p. S75, vol. 22). link>2016.
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Biocompatibility of biodegradable medical polymers. Science and Principles of Biodegradable and Bioresorbable Medical Polymers. Elsevier. doi>2016.
- 2016.
- 2016.
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Engineering In Vitro Differentiation Microenvironments to Study Heart Valve Calcification. TISSUE ENGINEERING PART A (p. S29, vol. 21). link>2015.
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Fluorescent Monitoring of Poly(lactic-co-glycolic Acid) Degradation and Extracellular Matrix Turnover of Engineered Tissue Constructs. TISSUE ENGINEERING PART A (p. S99, vol. 21). link>2015.
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Multi-functional PLGA Scaffolds For Vascularization In Bone Tissue Constructs. TISSUE ENGINEERING PART A (p. S126, vol. 21). link>2015.
- 2015.
- 2014.
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Label free cell tracking in 3-D tissue engineering constructs with high resolution imaging. DYNAMICS AND FLUCTUATIONS IN BIOMEDICAL PHOTONICS XI (vol. 8942). link> doi> full text>2014.
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Characterisation and optimisation of the GP Thrombus Aspiration Device for the treatment of acute ischaemic stroke. CEREBROVASCULAR DISEASES (p. 345, vol. 37). link>2014.
- 2013.
- 2012.
- 2011.
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A Morphological Study of Cell Aggregations on Mineralization. 8TH INTERNATIONAL CONFERENCE ON CELL & STEM CELL ENGINEERING (ICCE) (pp. 9-12, vol. 30). link>2011.
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Mechanical Conditioning Using Magnetic Nanoparticles Bound to PDGF Receptors on HBMSCs Promotes the Smooth Muscle Alpha Actin (SMA) Expression. 8TH INTERNATIONAL CONFERENCE ON CELL & STEM CELL ENGINEERING (ICCE) (pp. 23-25, vol. 30). link>2011.
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Online Monitoring the Mechanical Remodeling of Hydrogels by Corneal Fibroblasts. 8TH INTERNATIONAL CONFERENCE ON CELL & STEM CELL ENGINEERING (ICCE) (pp. 1-+, vol. 30). link>2011.
- 2010.
- 2010.
- 2009.
- 2009.
- 2009.
- 2009.
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Dual-Camera Spherical Indentation System for Examining the Mechanical Characteristics of Hydrogels. 4TH EUROPEAN CONFERENCE OF THE INTERNATIONAL FEDERATION FOR MEDICAL AND BIOLOGICAL ENGINEERING (pp. 2011-2014, vol. 22). link>2009.
- 2008.
- 2008.
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Tendon collagen orientation and crimp pattern characterized by PSOCT. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (pp. A28-A29, vol. 89). link>2008.
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Dynamic studies of biomimetic coated polycaprolactone nanofiber meshes as bone extracellular matrix analogues. TISSUE ENGINEERING PART A (pp. 723-724, vol. 14). link>2008.
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Modified collector geometry for electrospun nanofibers. TISSUE ENGINEERING PART A (pp. 881-882, vol. 14). link>2008.
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Novel technique for HA particle coating within 3D polymeric structures. TISSUE ENGINEERING PART A (p. 890, vol. 14). link>2008.
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Real time monitoring of scaffold degradation under culture conditions. TISSUE ENGINEERING PART A (p. 903, vol. 14). link>2008.
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Visualization of structural evolution in tissue engineering tendon. TISSUE ENGINEERING PART A (p. 795, vol. 14). link>2008.
- 2008.
- 2008.
- 2008.
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Micro-Shaft-Poking - a Novel Instrument for Mechanically Characterizing Soft Biomimetic Membrance. In TFB. Filho & H. Gamboa (Eds.). BIODEVICES (2) (pp. 210-215). INSTICC - Institute for Systems and Technologies of Information, Control and Communication. link>2008.
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Exploring fluorescence as a tool for real-time monitoring of scaffolds degradation. TISSUE ENGINEERING (p. 1694, vol. 13). link>2007.
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Interaction of cells with novel biodegradable cryogels in bioreactors. TISSUE ENGINEERING (p. 1718, vol. 13). link>2007.
- 2007.
- 2007.
- 2007.
- 2007.
- 2007.
- 2006.
- 2006.
- 2005.
- 2005.
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A study of the effects of seeding density, media flow and biochemical stimuli on the osteogenic differentiation of Mesenchymal Stem Cells. Transactions of the Combined Meeting of the Tissue Engineering Society International ? European Tissue Engineering Society Meeting.2004.
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The effects of a 3D environment on the osteogenic differentiation of Mesenchymal Stem Cells. Transactions of Tissue and Cell Engineering Society Spring Meeting.2004.
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Effect of microtopographical cue on human corneal keratocytes orientation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (p. U254, vol. 44). link>2003.
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Reconstruction of 3D human cornea using processed porcine cornea as a biological scaffold. SOE 2003: XIV CONGRESS OF THE EUROPEAN SOCIETY OF OPHTHALMOLOGY (pp. 275-280). link>2003.
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In vitro monitoring of cytochrome oxidase activity in neuronal cells. PROCEEDINGS OF THE 20TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOL 20, PTS 1-6 (pp. 2939-2940, vol. 20). link>1998.
Funding
- 2016 £6000, The British Council Newton Fund: PhD Placement grant (PI)
- 2015 £55,000, EPSRC CDT PhD studentship (PI), ‘Tissue engineering retinal and glaucoma eye models for better clinical treatment’
- 2015 £30,000, EPSRC, min-project (PI), Diagnostic tool to identify donor dependent heterogeneity population
- 2015 £29,000 , Acorn fund (Co-I), ‘A tissue engineering approach to improve lung function and clinical outcome in patients with emphysema’
- 2015 £195,000, MRC (Co-I), ‘Hub of engineering and exploiting the stem cell niche’
- 2015 £12,000 Chinese Studentship Council (PI), One year joint PhD studentship, ‘Novel peptides and surface modification strategies for anti-microbial devices’
- 2014 €181,000 EC Maria Curie incoming fellowship (PI), ‘Smart scaffolds for bone regeneration’
- 2014 £12,000 UHNS fund (PI), ‘Prolapse mechanism study with ethical approval for 100 patient samples’
- 2014 £81,000 PhD studentship (PI), Jordan local organization, ‘New strategies for cartilage regeneration’
- 2014 £100,000 PhD studentship (PI), Iraqi Government, ‘Pseudoislet formation on diabetes study’
- 2014 £72,000 PhD studentship (PI), Rivers state sustainable development agency, Nigeria, ‘Prolapse and ageing study’
- 2014 £100,000 Medical Institute of North Staffordshire (PI), ‘Better glaucoma treatment’
- 2013 ¥880,000 Chinese NSFC (Co-I), ‘New bioorganic-metal for ship antifouling and drag reduction’
- 2013 £100,000 EPSRC manufacture centre (Co-I), ‘Challenge-Led Regenerative Medicine Manufacturing Research’
- 2012 £104,000 BHF PhD Studentship (PI), ‘Development of a human 3D tissue-engineered blood vessel model for the study of haemostasis’
- 2012 £20,000 NHS Charitable fund (PI), ‘Development of a rapid bone formation technique for clinical applications’
- 2012 £371,000 EU FP7 project (Co-I), ‘Biodesign’
- 2012 £11,400 Royal society of International exchange (PI), ‘Control and mapping of mechanical signals in pre-vascularized engineered bone’
- 2012 £25,000 Acorn fund (PI), PhD studentship, ‘Acceleration of bone formation’
- 2011 2 month high magnetic field time and secondment funding, EuroMagNET II (PI), ‘Generation of orthogonal aligned fibers in hybrid hydrogels for corneal regeneration’
- 2011 £68,000 EPSRC DTC PhD studentship (Co-I), ‘Generating 3D neuronal networks in vitro – towards therapies for Huntington’s disease’
- 2010 £68,000 EPSRC DTC PhD studentship (Co-I), ‘Development new nanotechnology for spinal cord repair’
- 2010 £21,000 Acorn fund (PI), PhD studentship, ‘Study of calcification mechanism in heart valve’
- 2009 £68,000 EPSRC DTC PhD studentship (PI), ‘Development new corneal model for drug screening’
- 2009 € 90,000 EU, 7th Framework, Marie Curie Action (PI), ‘Development of new strategies for osteochondral regeneration
- 2008 £9,000 BBSRC pathfinder (PI), ‘Development and commercialization of a surgical phantom system for the brain research, therapy and education’
- 2008 £10,000 The Innovation Keele (PI), one postdoctoral, ‘Development of phantom kit for mammal brain therapeutic surgery’
- 2007 £413,000 BBSRC (PI), one postdoctoral, ‘Novel in vitro corneal model with on-line mechanical characterisation for pharmaceutical screening and tissue engineering’
- 2007 £22,000 Acorn fund (Co-I), PhD student, ‘Study of cancer cell sensitivity to chemotherapy and tumour cell invasion’
- 2007 £525,000 BBSRC (Co-I), two postdoctorals, ‘In vitro (pre)construction of neural circuits in transplantable, biodegradable scaffolds for CNS repair in vivo’
- 2006 £54,000 BBSRC CASE studentship (PI), ‘Development of degradable nanofiber scaffolds for regenerative medicine’
- 2006 £20,000 Institute of orthopaedics, Oswestry (Co-I), ‘Development of nanofiber based constructs for regenerative medicine’
- 2005 £280,000 EU network, EXPERTISSUE (Co-PI), ‘Novel therapeutic strategies for tissue engineering of bone and cartilage using second generation biomimetic scaffolds’
- 2005 £60,000 Marie Curie scholarship (PI), PhD studentship, ‘Novel sensing scaffolds for tissue engineering’
- 2004 £171,000 BBSRC (Co-I), one postdoctoral, ‘Quantitative on-line assessment of collagen fibre organization in connective tissue in vivo and during conditioning in vitro’
- 2003 £207,000 EPSRC (PI), one postdoctoral and one PhD studentship, ‘Development of mechano-active scaffolds for tissue engineering’
School address:
School of Pharmacy and Bioengineering
Hornbeam Building
Keele University
Staffordshire
ST5 5BG
Research centre address:
School of Pharmacy and Bioengineering
Guy Hilton Research Centre
Thornburrow Drive
Stoke-on-Trent
ST4 7QB
Tel: +44 (0) 1782 674988
Undergraduate enquiries:
Email: enquiries@keele.ac.uk
Tel: +44 (0)1782 734010
Postgraduate enquiries:
Please contact the CPD4ALL team:
Email: phab.postgraduate@keele.ac.uk
Keele Centre for Medicines Optimisation (KCMO)
Tel: +44 (0)1782 733831 / 734131
The Virtual Patient project enquiries:
Contact our Digital Development team:
Email: pharmacy.digital@keele.ac.uk