Teaching

Current and previous teaching duties, undergraduate, professional and/or postgraduate

Current roles:

  • Supervisor for Dissertation students, International Students, Supervisor for 3 PhD students, PBL teaching course for second year medicine students; lecturer in Pharmacology, microbiology, molecular biology and Biochemistry for the school of medicine;

Previous roles:

  • Supervisor for Undergraduates, PhD students and newcomers PostDocs. Supervisor for second year Dissertation students, International Students, Nuffield undergraduates, University Undergraduates, Master students (MHS microbiology, MRes, MSc, etc),
  • Cosupervisor for 3 PhD students (Rachael Magwaza, Gabriel Schrecker & Adefunke Ogunkanbi) Internal Examiner of the committee for the PhD thesis of Miss Beriwan Ali.

Supervision of research students:

  • 2019 – Supervision of 2 undergraduates, 1 post-graduated and 2 PhD students
  • 2018 – Supervision of 2 undergraduates, 1 post-graduated and 2 PhD students
  • 2017- Supervision of 3 undergraduates, 1 post-graduated and 3 PhD students
  • 2016- Supervision of 7 undergraduates, 5 post-graduated and 2 PhD students
  • 2015 – Supervision of 6 undergraduates and one post-doc at the Faculty of Life Sciences – University of Manchester
  • 2014 - Supervision of two undergraduate students at the Faculty of Life Sciences – University of Manchester
  • 2011-2014 Supervisor of a PhD student, Mario Carucci– successfully graduated
  • 2009 – External Examiner of the committee for graduation of Mpharm students at the University of Milan
  • 2008 - Invited as assistant teacher at a prestigious international course on Biology of Parasitism (BoP) international summer course at the MBL – WoodsHole MA
  • 2008 – Invited for teaching at classes for Pharmaceutical Chemistry and Technology course at University of Milan
  • 2004-11 – CoSupervising teacher and trainer of 6 PhD students and 3 newcomers PostDoc at Washington University and the University of Perugia


My specific competences are in the field of microbiology, parasitology, biochemistry, molecular biology, genetics,
protein chemistry and enzymology.

 

Further information

Innovative work and contributions to the reform and/or development of curriculum or assessment My job has been always conducted with contagious enthusiasm and dedication. 100% of the Students joined in and some demonstrated a driving role. No one quitted despite the fact that some experienced grave difficulties in life.
I liaise with the teaching committee and I often get involved productive discussions for innovations in the methodology applied.
Any evidence or results of external assessments of teaching ability About 90% of people I trained remained in science or revealed themselves successful in the acquired techniques and knowledge.
Some of them have become principal investigators, staff at GSK or in other institutions, moved to the public sector, or secured prestigious fellowships in their own countries for PhD.

Selected Publications

  • Pool MR and Russo I. 2018. The perplexing PEXEL protein secretory pathway. Nature Reviews Microbiology, 969-970. doi> link>
  • Lehmann C, Ser Ying Tan M, de Vries L, Russo I, Sanchez M, Goldberg D. 2018. Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite. PLoS Pathogens, vol. 14(5), Article e1007031. doi> link> full text>
  • Alnabulsi S, Hussein B, Santina E, Alsalahat I, Kadirvel M, Magwaza R, Bryce R, Schwalbe C, Baldwin A, Russo I, Stratford I, Freeman S. 2018. Evaluation of analogues of furan-amidines as inhibitors of NQO2. Bioorganic and Medicinal Chemistry Letters, vol. 28(8), 1292-1297. doi> link> full text>
  • Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, Finegan K, Wang W, Wang J, Gray N, Vermi W, Xia Z, Tournier C. 2018. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proceedings of the National Academy of Sciences, vol. 115(12), E2801-E2810. doi> link> full text>
  • Nasamu A, Glushakova S, Russo I, Vaupel B, Oksman A, Kim A, Fremont D, Tolia N, Beck J, Meyers M, Niles J, Zimmerberg J, Goldberg D. 2017. Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion. Science, vol. 358(6362), 518-522. doi> link> full text>

Full Publications List show

Journal Articles

  • Pool MR and Russo I. 2018. The perplexing PEXEL protein secretory pathway. Nature Reviews Microbiology, 969-970. doi> link>
  • Lehmann C, Ser Ying Tan M, de Vries L, Russo I, Sanchez M, Goldberg D. 2018. Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite. PLoS Pathogens, vol. 14(5), Article e1007031. doi> link> full text>
  • Alnabulsi S, Hussein B, Santina E, Alsalahat I, Kadirvel M, Magwaza R, Bryce R, Schwalbe C, Baldwin A, Russo I, Stratford I, Freeman S. 2018. Evaluation of analogues of furan-amidines as inhibitors of NQO2. Bioorganic and Medicinal Chemistry Letters, vol. 28(8), 1292-1297. doi> link> full text>
  • Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, Finegan K, Wang W, Wang J, Gray N, Vermi W, Xia Z, Tournier C. 2018. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proceedings of the National Academy of Sciences, vol. 115(12), E2801-E2810. doi> link> full text>
  • Nasamu A, Glushakova S, Russo I, Vaupel B, Oksman A, Kim A, Fremont D, Tolia N, Beck J, Meyers M, Niles J, Zimmerberg J, Goldberg D. 2017. Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion. Science, vol. 358(6362), 518-522. doi> link> full text>
  • Alnabulsi S, Santina E, Russo I, Hussein B, Kadirvel M, Chadwick A, Bichenkova E, Bryce R, Nolan K, Demonacos C, Stratford I, Freeman S. 2016. Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria. European Journal of Medicinal Chemistry, vol. 111, 33-45. doi> link>
  • Gambini L, Rizzi L, Pedretti A, Taglialatela-Scafati O, Carucci M, Pancotti A, Galli C, Read M, Giurisato E, Romeo S, Russo I. 2015. Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region. PLOS ONE, vol. 10(11), e0142509. doi> link> full text>
  • Moretti E, Collodel G, Mazzi L, Russo I, Giurisato E. 2015. Ultrastructural study of spermatogenesis in KSR2 deficient mice. Transgenic Research, vol. 24(741). doi> link>
  • Russo I, Babbitt S, Muralidharan V, Butler T, Oksman A, Goldberg DE. 2010. Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte. Nature, vol. 463(7281), 632-636. doi> link>
  • Fennell C, Babbitt S, Russo I, Wilkes J, Ranford-Cartwright L, Goldberg DE, Doerig C. 2009. PfeIK1, a eukaryotic initiation factor 2α kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation. Malaria Journal, vol. 8(1), 99. doi> link> full text>
  • Russo I, Oksman A, Goldberg DE. 2009. Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus. Molecular Microbiology, vol. 72(1), 229-245. doi> link> full text>
  • Russo I, Oksman A, Vaupel B, Goldberg DE. 2009. A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development. Proceedings of the National Academy of Sciences, vol. 106(5), 1554-1559. doi> link>
  • De Filippis V, Russo I, Vindigni A, Di Cera E, Salmaso S, Fontana A. 2008. Incorporation of noncoded amino acids into the N‐terminal domain 1‐47 of hirudin yields a highly potent and selective thrombin inhibitor. Protein Science, vol. 8(10), 2213-2217. doi> link>
  • De Filippis V, Colombo G, Russo I, Spadari B, Fontana A. 2002. Probing the Hirudin−Thrombin Interaction by Incorporation of Noncoded Amino Acids and Molecular Dynamics Simulation † , ‡. Biochemistry, vol. 41(46), 13556-13569. doi> link>

Research details

Ilaria Russo has over 15-years-long experience in studying malaria, a disease responsible for hundreds of thousand deaths per year. Her lab provides great contributions in cell biology, genetics and
biochemistry of Plasmodium falciparum, the deadliest strain causing malaria in humans. Well-known in the field of malaria for her seminal work and cutting-edge discoveries into malaria cell biology and pathology, her research aims to tackle these urgent unmet medical needs affecting a third of the world population with an important translational ethos. She is recognized as particularly technically skilled that granted her success in facing highly challenging tasks and projects that delivered hard-to achieve results and breakthrough discoveries. The field received from her important technological advancements due to elegant creativity in designing and validating new techniques. She is currently conducting cutting-edge research in new antimalarial drugs, discovery and validation of new targets, investigation of the cell cycle regulation and host-pathogen interaction. She is also operating in the RD of Congo in collaboration with two NGOs, where she has established the first diagnostic center in the region of Katanga, a quickly growing institute with strategical value for the WHO. Her skills, projects and research goals are now interconnecting with the high potential platform offered by the AchilleS’s OMVs and its team of world-wide famous and talented vaccinologists. This activity has recently won about 60milion Euros for 8 years from the EU Malaria fund for an innovative vaccine project for malaria, that will include her academic laboratory.