Scientific Programme

The Tenth Keele Meeting on Aluminium; 23-27 February 2013; England

The scientific programme is now available below, or as a PDF which can be downloaded. If the PDF opens in your web browser and you wish to save it or open it externally, on most Windows and Linux systems it is possible to right-click the link and select "save target as...", "save as...", "save linked file..." etc. from the menu that appears. Apple users may wish to try CTRL + Click, and smartphone / tablet users may wish to try tapping and holding the link.

You may also be interested in viewing the 10th Keele Meeting Abstracts Book (PDF file).

Saturday 23rd February 2013

17.00 Registration and Poster Assembly  

Welcome to Meeting / Welcome Buffet 

Sunday 24th February 2013

The Conference is Open!

Session 1

*Denotes presentation by a student.

Chair: Tamas Kiss (Szeged University, Szeged, Hungary)

8.25 Introduction by the Chair  
8.30 Platform 1
Natural organic matter adsorption on a lateral AlOOH surface elucidated with
ab initio molecular dynamics.

Dominique Costa (ENSCP Chemie-Paristech, Paris, France)
8.50 Discussion
9.00 Oral Poster 1
Adsorption of inositol phosphate on gibbsite (γγ-Al(OH)3).
Oleg Antzutkin (Luleå University of Technology, Luleå, Sweden)
9.05 Discussion
9.10 Platform 2
Interaction between Al3+ and 2,3-dihydroxyterephthallic acid as a model
compound for Inogashira fulvic acid.
Takushi Yokoyama (Kyushu University, Higachi-ku, Fukuoka, Japan)
9.30 Discussion
9.40  Oral Poster 2*
Interaction between Al3+ and simple dicarboxylic acids at pH 3.
Mayumi Etou (Kyushu University, Higachi-ku, Fukuoka,Japan)
9.45 Discussion
9.50 Platform 3
Detecting toxicant interactions in mixtures of toxicants. Special consideration of
ionic toxicants.
Thomas Kinraide (USDA, Beaver, West Virginia, USA)
10.10 Discussion
10.20 COFFEE
10.40 Platform 4
Computer-aided speciation of small aluminium silicate clusters in aqueous
Giorgio Lanzani (University of Oulu, Oulu, Finland)
11.00 Discussion
11.10 Oral Poster 3
Aluminium-silicon interactions in mild pH and ionic strength conditions
Jaakko Rämö (University of Oulu, Oulu, Finland)
11.15 Discussion

Oral Poster 4
Computer simulations of the structure, formation and growth of hydroxyaluminosilicates, at the level of individual and collections of molecules
James Beardmore (Keele University, United Kingdom)

11.25 Discussion
11.30 Platform 5
Can Al3+ promote the Fenton reaction and oxidative stress?
Xabier Lopez (Euskal Herriko University, Donostia, Basque Country)
11.50  Discussion
12.00 Oral Poster 5
Unveiling the coordination of aluminium to amyloid-ββ peptide with
computational chemistry.
Jon Mujika (Euskal Herriko University, Donostia, Basque Country)
12.05 Discussion
12.10 Platform 6
Hydroxypyrones, a fascinating family of chelating agents for Al(III).
Guido Crisponi (Citadella University, Cagliari, Italy)
12.30 Discussion
12.40 Oral Poster 6
Complex formation equilibria of substituted phenols with Al3+ and Fe3+.
Miriam Crespo-Alonso (Citadella University, Cagliari, Italy)
12.45 Discussion
12.50  Oral Poster 7*
Complexation of Al(III) with hydroxypyridine(di)carboxylic acids as new
possible chelating agents in neurodegenerative diseases.
Éva Sija (University of Szeged, Szeged, Hungary)
12.55 Discussion
13.00  LUNCH 
Session 2

*Denotes presentation by a student.
Chair: Lubos Boruvka (Czech University of Life Science, Czech Republic)

14.15   Introduction by the Chair  
14.20  Platform 7
Molecular mechanisms of crop adaptation to acid soils.
Leon Kochian (USDA-ARS, Cornell University, New York, USA)
14.40 Discussion
14.50  Platform 8
Cellular distribution of aluminium and other elements in leaves of native plant
species of Brazilian Cerrados.
Leide de Andrade (Embrapa Cerrados, Planaltina, Brazil)
15.10 Discussion
15.20 Oral Poster 8*
Effect of aluminium ions on hydrangea sepals and viburnum drupes.
Blaine Groat (Virginia Military Institute, Lexington, Virginia, USA)
15.25 Discussion
15.30 Oral Poster 9
Aluminium, iron and manganese, do they limit the determination of anionic
substances by ion chromatography?
Ond?ej Drábek (Czech University of Life Sciences, Prague, Czech Replublic)
15.35 Discussion
15.40  Platform 9
Amelioration of iron toxicity, a mechanism for aluminium-induced growth
stimulation in tea plants.
Charlotte Poschenrieder (Universidad Autónoma de Barcelona, Spain)
16.00 Discussion
16.10 TEA
16.30 Oral Poster 10
Long term changes in aluminium concentrations and fluxes in Czech streams
recovering from acidification.
Pavel Kram (Czech Geological Survey, Prague, Czech Republic)
16.35  Discussion
16.40 Platform 10
Effect of salicylic acid on the attenuation of aluminium toxicity in cell
suspensions of Coffea arabica L.
Teresa Hernández-Sotomayor (CICY, Mérida, México)
17.00 Discussion
17.10 Oral Poster 11
The role of diacylglycerol in aluminium toxicity in plants.
P?emysl Pejchar (Academy of Sciences of Czech Republic, Prague, Czech Republic)
17.15 Discussion 
17.20 Platform 11
Aluminium-induced cell death involves both mitochondria and the vacuole in
plant cells.
Yoko Yamamoto (Okayama University, Kurashiki, Japan)
17.40 Discussion
17.50 Oral Poster 12
Influence of Al3+on light-induced membrane potential changes in Nitellopsis
optusa cells.
Vilma Kisnierien÷ (Vilnius University, Vilnius, Lithuania)
17.55 Discussion
18.00 Platform 12
Physiological and oxidative responses of two Avena sativa genotypes and
Cucumis sativis seedlings to aluminium in nutrient solution.
Maria Rosa Schetinger (Federal University of Santa Maria, Santa Maria, Brazil)
18.20 Discussion
18.30 Oral Poster 13*
Differential speed of activation in antioxidant systems in three oat genotypes.
Luciane Pereira (University of Santa Maria, Santa Maria, Brazil)
18.35 Discussion
18.40 Oral Poster 14*
The bioleaching of aluminium from solid aluminium oxide by a filamentous
Ivana Pifkova (Comenius University in Bratislava, Bratislava, Slovakia)
18.45 Discussion
First Evening
20.15 DINNER

Monday 25th February 2013

Session 3

*Denotes presentation by a student.
Chair: Paula Goncalves (University of Aveiro, Aveiro, Portugal)

8.25 Introduction by the Chair
8.30 Platform 13*
Comparative study on the binding of Al3+ and nano-Al13 with salmon sperm DNA
and calf thymus DNA.
Fei Ma (Nanjing Normal University, Nanjing, China)
8.50 Discussion 
9.00 Oral Poster 15
Carbon nanomaterials as modified electrodes for the determination of trace
aluminium (III) in biological fluids using 8-hydroxyquinone.
Xiao Di Yang (Nanjing Normal University, Nanjing, China)
9.05 Discussion
9.10 Platform 14*
Cholesterol effect on (Na+K+)ATPase inhibition by submillimolar aluminium.
Madina Artykbayeva (University of Aveiro, Aveiro, Portugal)
9.30 Discussion
9.40 Oral Poster 16
Acute and chronic neurotoxicity of aluminium oxide nanoparticles in mice.
Qinli Zhang (Shanxi Medical University, Taiyuan, China)
9.45 Discussion
9.50 Oral Poster 17
Aluminium and calcium homeostasis; influence of insulin-like growth factor 1
(IGF-1) on intestinal absorption.
Daniel Orihuela (Universidad Nacional del Litoral, Sante Fe, Argentina)
9.55 Discussion
10.00 COFFEE
10.20 Platform 15
Age dependence in the accumulation and elimination of aluminium in rats.
Denise Bohrer (Federal University of Santa Maria, Brazil)
10.40 Discussion
10.50 Platform 16
Effect of long term exposure to aluminium and a high fat diet on NTPDase and
5’-nucleotidase activities in lymphocytes and platelets of rats.
Rosilene Kaizer (Instituto Federal de Educação Ciência e Tecnologia do Rio Grande
do Sul, Brazil)
11.10 Discussion
11.20 Platform 17
No effect of long term low dosage of Al maltolate towards Th2 immune response
in young rats.
Guoo-Shyng Wang Hsu (Fu-Jen Catholic University,Taipei, Taiwan)
11.40 Discussion
11.50 Platform 18
Aluminiun adjuvant-induced mitochondrial alterations.
Håkan Eriksson (Malmö University, Malmö, Sweden)
12.10 Discussion
12.20 Platform 19
Administration of aluminium in vaccine-relevant exposures in neonatal mice is
associated with long term adverse neurological outcomes.
Christopher Shaw (University of British Columbia, Vancouver, Canada)
12.40  Discussion
12.50 Platform 20
Aluminium enhances inflammation and decreases mucosal healing in
experimental colitis in mice.
Mathilde Body-Malapel (University of Lille 2, Lille, France)
13.10 Discussion
13.20 LUNCH


20.00 DINNER  

Film (English Language Premiere)

Dirty Little Secret
The Aluminium Files

A Film by Bert Ehgartner

Tuesday 26thFebruary 2013

Session 4

*Denotes presentation by a student

Chair: David Chettle (McMaster University, Hamilton, Canada)

8.25 Introduction by the Chair 

Platform 21
Excessive aluminium accumulation in the bones of patients on long term
parenteral nutrition.
Patrick Parsons (State University of New York, Albany, USA)

8.50 Discussion
9.00 Oral Poster 18
Assessing inter-laboratory performance for serum Al in the New York State
Proficiency Testing programme; implications for monitoring exposure to Al
in parenteral nutrition patients.
Pamela Kruger (New York State Department of Health, Albany, USA)
9.05 Discussion
9.10 Oral Poster 19*
Hot watery infusion of Hibiscus sabdariffa petals, a potential source of
aluminium in the human diet.
Adéla Fra?ková (Czech University of the Life Sciences, Prague, Czech Republic)
9.15 Discussion
9.20 Oral Poster 20
A pilot study measuring aluminium in bone in Alzheimer’s and referent
subjects;work in progress.
David Chettle (McMaster University, Hamilton, Canada)
9.25 Discussion
9.30 Platform 22
Absorption and metabolism of aluminium and its influence on gene expression to
cause disease.
Shunsuke Meshitsuka (Totorri University School of Medicine, Yonago, Japan)
9.50 Discussion
10.00 COFFEE
10.20 Platform 23
Effect of aluminium on migratory and invasive properties of human breast
cancer cells in culture.
Philippa Darbre (University of Reading, Reading, UK)
10.40 Discussion
10.50 Platform 24
Aluminium chloride transforms cultured mammary epithelial cells.
Stefano Mandriota (University Hospital of Geneva, Geneva, Switzerland)
11.10 Discussion

Platform 25
The relationship between aluminium, carbonyls and interleukins in the microenvironment of normal and cancerous breast tissue.
Ferdinando Mannello (University “Carlo Bo”, Urbino, Italy)

11.40 Discussion
11.50 Oral Poster 21*
Physico-chemical characterisation of clinically-approved and research aluminium-based adjuvants.
Emma Shardlow (Keele University, Staffordshire, UK)
11.55 Discussion
12.00 Platform 26
Aluminium-hydroxide induced macrophagic myofasciitis (MMF); predictive scores and biomarkers.
François-Jérôme Authier (Paris Est-Creteil University, France)
12.20 Discussion
12.30 Platform 27
Death following human papillomavirus (HPV) vaccination; an auto-immune adjuvant-mediated adverse reaction?
Lucija Tomljenovic (University of British Columbia, Vancouver, Canada)
12.50 Discussion
13.00 LUNCH
Session 5

*Denotes presentation by a student

Chair: Leon Kochian (USDA-ARS, Cornell University, New York, USA)

14.25 Introduction by the Chair 
14.30 Platform 27
Caspase-3 short hairpin RNA interference targeted to an Alzheimer’s disease
animal model induced by aluminium blocks neural cell death and defects of
learning and memory.
Qiao Niu (Shanxi Medical University, Taiyuan, China)
14.50 Discussion
15.00 Platform 28
Aluminium entry into the brain; studies in the cerebral vasculature and in
human brain microvessel endothelial (hBMEC) cells.
Walter Lukiw (Louisiana State University Health Sciences Centre, New Orleans,
15.20 Discussion

Oral Poster 22
Relationship of aluminium intoxication with neurodegenerative disease.
Alessandro Fulgenzi (University of the Studies of Milan, Milan, Italy)

15.35 Discussion
15.40 Platform 30
Colocalisation of aluminium and iron in cell nuclei in the brains of patients with
Alzheimer’s disease.
Sakae Yumoto (Yumoto Institute of Neurology, Tokyo, Japan)
16.00 Discussion
16.10 Platform 31
Aluminium, illicit drugs, neuropsychiatric impairment and disability; an
evidence-based approach.
Paolo Prolo (Swiss Disability Insurance, Bellinzona, Switzerland
16.30 Discussion
16.40 TEA
Final Session

Chair: Chris Exley (Keele University, UK)

17.10 Introduction by the chair to the JD Birchall Memorial Lecture 

The JD Birchall Memorial Lecture

From the coordination chemistry to the biological chemistry
of Aluminium

Professor Tamas Kiss
University of Szeged, Szeged, Hungary

18.20 Discussion
20.00 Conference Dinner

List of Additional Posters

*Denotes presentation by a student.

Session 1


Session 2

Poster 1

Labile Al content or BC/Al ratio in soil: what controls tree seedlings growth?
Lubos Boruvka (Czech University of Life Sciences, Prague, Czech Republic)

Poster 2

The influence of altitude on Al speciation in samples originating from beach and spruce forests.
Lubos Boruvka (Czech University of Life Sciences, Prague, Czech Republic)

Poster 3

Salicylic acid is involved in the mechanism of response to aluminum toxicity in cell suspensions of Capsicum chinense Jacq.
Armando Munoz-Sanchez (CICY, Merida, Mexico)

Poster 4*

The combined effect of Aluminium and tritium on the plant cell membrane bioelectrical parameters.
Olga Sevriukova (Vilnius University, Vilnius, Lithuania)

Poster 5

Physiological and oxidative stress responses to aluminium in three oat genotypes grown hydroponically.
Vera Morsch (Federal University of Santa Maria, Brazil).

Poster 6*

Localisation of callose in rice tissue using aniline blue staining and immunofluorescence.
Ian Stokes (Keele University, United Kingdom)


Session 3

Poster 1*

Aluminium effect on Escherichia coligrowth and death
Madine Artykbayeva (University of Aveiro, Aveiro, Portugal)

Poster 2*

Effects of aluminium maltolate ingestion on the immune response of SD neonates.
Hsin-Ya Lin (Fu-Jen Catholic University,Taipei, Taiwan)

Poster 3*

Heme oxygenase-1 induction by ROS-JNK pathway plays a role in aluminium-induced anemia.
Chia-Yeh Lin (Fu-Jen Catholic University,Taipei, Taiwan)

Poster 4*

Transcellular transport of alumina nanoparticles: A study on blood-brain barrier model in vitro.
Hui-ting Peng (Shanxi Medical University, Taiyuan, China)

Poster 5*

Effects on long-term potentiation and the expression of AMPA receptor subunits in rat exposed to aluminum in vivo.
Jing Song (Shanxi Medical University, Taiyuan, China)


Session 4

Poster 1*

In vivo neutron activation analysis of aluminium in bone: further refinements.
Hedi Mohseni (McMaster University, Hamilton, Canada)

Poster 2

Modelling absorption efficiency of elements via oral exposure in humans.
Yen Le (Radboud University, Nijmegen, The Netherlands

Poster 3*

Antiperspirants, aluminium salts and relationship with breast cancer.
Caroline Linhart (Innsbruck Medical University, Austria)

Poster 4

Selective elevation of circulating CCL2/MCP1 levels in patients with longstanding post-vaccinal macrophagic myofasciitis and ASIA.
Romain Gherardi (University of Paris Est, Creteil, France)

Poster 5

Tyrosine as a depot adjuvant for use in allergy-specific immunotherapy.
Simon Hewings (Allergy Therapeutics, Worthing, UK)

Poster 6

Aluminium adjuvants potentiate the immune response via interaction with dendritic cells – but where does the aluminium go?
Matthew Mold (Keele University, United Kingdom)


Session 5

Poster 1*

Cognitive disorders and tau-protein expression among retired smelting workers exposed to aluminium.
Xiao-ting Lu (Shanxi Medical University, Taiyuan, China)

Poster 2*

Spectrometric methods to analyse and quantify the silicon content of mineral waters.
Krista Jones (Keele University, United Kingdom)