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    Research areas

    Contact: Ian Scott, i.scott@keele.ac.uk

     Example recent publications:

    1. Scott IC, Whittle R, Bailey J, Twohig H, Hider SL, Mallen CD, Muller S, Jordan KP. Analgesic prescribing in patients with inflammatory arthritis in England: observational studies in the Clinical Practice Research Datalink, Rheumatology (Oxford), kead463. Advance online publication. https://doi.org/10.1093/rheumatology/kead463.
    2. Scott IC, Whittle R, Bailey J, Twohig H, Hider SL, Mallen CD, Muller S, Jordan KP. Rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis epidemiology in England from 2004 to 2020: An observational study using primary care electronic health record data, The Lancet Regional Health - Europe, 2022;23:100519. https://doi.org/10.1016/j.lanepe.2022.100519.
    3. Muller S, Hider S, Machin A, Stack R, Hayward RA, Raza K, Mallen C. Searching for a prodrome for rheumatoid arthritis in the primary care record: A case-control study in the Clinical Practice Research Datalink, Seminars in Arthritis and Rheumatism, 2019;48:815–820. https://doi.org/10.1016/j.semarthrit.2018.06.008.
    4. Roughley M, Sultan AA, Clarson L, Muller S, Whittle R, Belcher J, Mallen CD, Roddy E. Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study, Arthritis Res Ther. 2018;20:243. https://doi.org/10.1186/s13075-018-1746-1.
    5. Partington RJ, Muller S, Helliwell T, Mallen CD, Abdul Sultan A. Incidence, prevalence and treatment burden of polymyalgia rheumatica in the UK over two decades: a population-based study, Ann Rheum Dis. 2018;77:1750-1756. https://doi.org/10.1136/annrheumdis-2018-213883

    Contact: Dahai Yu, d.yu@keele.ac.uk

    Example recent publications:

    1. Marshall M, Mason KJ, Edwards JJ, Mamas M, Bailey J, Heron N, Achana F, Frisher M, Huntley AL, Mallen CD, Png ME, Tatton S, White S, Jordan KP. Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed comorbid conditions: an electronic health record cohort study, Rheumatology Advances in Practice, in press.
    2. Mason KJ, Jordan KP, Heron N, Edwards JJ, Bailey J, Achana F, Chen Y, Frisher M, Huntley AL, Mallen CD, Mamas MA, Png ME, Tatton S, White S, Marshall M. Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: a linked electronic health record cohort study, Musculoskeletal Care, 2023;21:749-762. https://doi.org/10.1002/msc.1748
    3. Yu D, Jordan KP, Wilkie R, Bailey J, Fitzpatrick J, Ali N, Niblett P, Peat G. Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004 and 2019, Rheumatol Adv Pract, 2022; 7: rkac106. https://doi.org/10.1093/rap/rkac106.
    4. Yu D, Peat G, Jordan KP, Bailey J, Prieto-Alhambra D, Robinson DE, Strauss VY, Walker-Bone K, Silman A, Mamas M, Blackburn S, Dent S, Dunn K, Judge A, Protheroe J, Wilkie R. Estimating the population health burden of musculoskeletal conditions using primary care electronic health records, Rheumatology (Oxford), 2021;60:4832-4843. https://doi.org/10.1093/rheumatology/keab109
    5. Yu D, Jordan KP, Snell KIE, Riley RD, Bedson J, Edwards JJ, Mallen CD, Tan V, Ukachukwu V, Prieto-Alhambra D, Walker C, Peat G. Development and validation of prediction models to estimate risk of primary total hip and knee replacements using data from the UK: two prospective open cohorts using the UK Clinical Practice Research Datalink, Ann Rheum Dis, 2019;78:91-99. https://doi.org/10.1136/annrheumdis-2018-213894

    Contact: Mamas Mamas, m.mamas@keele.ac.uk

    Example recent publications:

    1. Weight N, Moledina S, Volgman AS, Bagur R, Wijeysundera HC, Sun LY, Chadi Alraies M, Rashid M, Kontopantelis E, Mamas MA. Socioeconomic disparities in the management and outcomes of acute myocardial infarction, Heart, 2023 Aug 9:heartjnl-2023-322601. https://doi.org/10.1136/heartjnl-2023-322601. Epub ahead of print.
    2. Jordan KP, Rathod-Mistry T, van der Windt DA, Bailey J, Chen Y, Clarson L, Denaxas S, Hayward RA, Hemingway H, Kyriacou T, Mamas MA. Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study, European Journal of Preventive Cardiology, 2023;30:1151-1161. https://doi.org/10.1093/eurjpc/zwad055
    3. Ajabnoor AM, Parisi R, Zghebi SS, Ashcroft DM, Faivre-Finn C, Morris C, Mamas MA, Kontopantelis E. Common cancer types and risk of stroke and bleeding in patients with nonvalvular atrial fibrillation: a population-based study in England, J Am Heart Assoc, 2023;12:e029423. https://doi.org/10.1161/JAHA.123.029423.
    4. Hinton J, Mariathas MN, Gabara L, Allan R, Nicholas Z, Kwok CS, Ramamoorthy S, Calver A, Corbett S, Jabbour RJ, Mahmoudi M, Rawlins J, Sirohi R, Wilkinson JR, Cook P, Martin GP, Mamas MA, Curzen N. Association between troponin level and medium-term mortality in 20000 hospital patients, Heart, 2023;109:1772-1777. http://dx.doi.org/10.1136/heartjnl-2023-322463.
    5. Cipolletta E, Tata LJ, Nakafero G, Avery AJ, Mamas MA, Abhishek A. Association between gout flare and subsequent cardiovascular events among patients with gout, JAMA, 2022;328:440-450. https://doi.org/10.1001/jama.2022.11390

    Contact: Kelvin Jordan, k.p.jordan@keele.ac.uk

    Example recent publications:

    1. Rathod-Mistry T, Marshall M, Campbell P, Bailey J, Chew-Graham CA, Croft P, Frisher M, Hayward R, Negi R, Robinson L, Singh S, Sumathipala A, Thein N, Walters K, Weich S, Jordan KP. Indicators of dementia disease progression in primary care: an electronic health record cohort study, European Journal of Neurology, 2021;28:1499-1510. https://doi.org/10.1111/ene.14710.
    2. Campbell P, Rathod-Mistry T, Marshall M, Bailey J, Chew-Graham CA, Croft P, Frisher M, Hayward R, Negi R, Singh S, Tantalo-Baker S, Tarafdar S, Babatunde O, Robinson L, Sumathipala A, Thein N, Walters K, Weich S, Jordan KP. Markers of dementia-related health in primary care electronic health records, Aging and Mental Health, 2021;25:1452-1462. https://doi.org/10.1080/13607863.2020.1783511.
    3. Rong R, Xu Q, Jordan KP, Chen Y. Perceived epidemic impacts and mental symptom trajectories in adolescents back to school after COVID-19 restriction: A longitudinal latent class analysis, Journal of Adolescent Health, 2023 Nov 14:S1054-139X(23)00494-9. https://doi.org/10.1016/j.jadohealth.2023.09.011. Online ahead of print.
    4. Chen Y, Farooq S, Edwards J, Chew-Graham CA, Shiers D, Frisher M, Hayward R, Sumathipala, A, Jordan KP. Patterns of symptoms before a diagnosis of first episode psychosis: a latent class analysis of UK primary care electronic health records, BMC Medicine, 2019;17:227. https://doi.org/10.1186/s12916-019-1462-y.
    5. Walker J, Liddle J, Jordan KP, Campbell P. Affective concordance in couples: a cross-sectional analysis of depression and anxiety within a population of 13,507 couples in primary care, BMC Psychiatry, 2017;17:190. https://doi.org/10.1186/s12888-017-1354-7.

    Contact: Sara Muller, s.muller@keele.ac.uk

    Example recent publications:

    1. Ashworth J, Bajpai R, Muller S, Bailey J, Helliwell T, Harrisson SA, Whittle R, Mallen CD. Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study, Lancet Reg Health Eur, 2023; 27:100579. https://doi.org/10.1016/j.lanepe.2022.100579.
    2. Roddy E, Bajpai R, Forrester H, Partington RJ, Mallen CD, Clarson LE, Padmanabhan N, Whittle R, Muller S. Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink, Ann Rheum Dis, 2023;82:1618-1625. https://doi.org/10.1136/ard-2023-224154.
    3. Abdul Sultan A, Mallen C, Muller S, Hider S, Scott I, Helliwell T, Hall LJ. Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study, BMC Med, 2019;17:154. https://doi.org/10.1186/s12916-019-1394-6.
    4. Abdul Sultan A, Whittle R, Muller S, Roddy E, Mallen CD, Bucknall M, Helliwell T, Hider S, Paskins Z. Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy, CMAJ, 2018;190:E581-E587. https://doi.org/10.1503/cmaj.170806.
    5. Bedson J, Chen Y, Ashworth J, Hayward RA, Dunn KM, Jordan KP. Risk of adverse events in patients prescribed long-term opioids: a cohort study in the UK Clinical Practice Research Datalink, European Journal of Pain, 2019;23:908-922. https://doi.org/10.1002/ejp.1357.

    Contact: Dahai Yu, d.yu@keele.ac.uk

    Example recent publications:

    1. Welsh VK, Mason KJ, Bailey J, Bajpai R, Jordan KP, Mallen CD, Burton C. Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study, British Journal of General Practice, 2023;73:e858-e866. https://doi.org/10.3399/bjgp.2022.0648.
    2. Peat G, Kiadaliri A, Yu D. Disparities in the age at osteoarthritis diagnosis: an indicator for equity-focused prevention, Rheumatology (Oxford), 2023;62:e240-e241. https://doi.org/10.1093/rheumatology/kead080.
    3. Yu D, Jordan KP, Wilkie R, Bailey J, Fitzpatrick J, Ali N, Niblett P, Peat G. Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004 and 2019, Rheumatol Adv Pract, 2022; 7: rkac106. https://doi.org/10.1093/rap/rkac106.
    4. Yu D, Wang Z, Cai Y, McBride K, Osuagwu UL, Pickering K, Baker J, Cutfield R, Orr-Walker BJ, Sundborn G, Jameson MB, Zhao Z, Simmons D. Ethnic differences in cancer rates among adults with Type 2 Diabetes in New Zealand from 1994 to 2018. JAMA Netw Open. 2022;5:e2147171. https://doi.org/10.1001/jamanetworkopen.2021.47171.
    5. Yu D, Zhao Z, Osuagwu UL, Pickering K, Baker J, Cutfield R, Orr-Walker BJ, Cai Y, Simmons D. Ethnic differences in mortality and hospital admission rates between Maori, Pacific, and European New Zealanders with type 2 diabetes between 1994 and 2018: a retrospective, population-based, longitudinal cohort study. Lancet Glob Health. 2021;9: e209-e217. https://doi.org/10.1016/s2214-109x(20)30412-5.

    Contact: Kayleigh Mason, k.mason@keele.ac.uk

    Example recent publications:

    1. Png ME, Mason KJ, Marshall M, Jordan KP, Bailey J, Frisher M, Heron N, Huntley AL, Mallen CD, Mamas MA, Tatton S, White S, Edwards JJ, Achana F. Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study, Curr Med Res Opin, 2023;19:1-8. https://doi.org/10.1080/03007995.2023.2271862.
    2. Burton C, Bajpai R, Mason KJ, Bailey J, Jordan KP, Mallen CD, Welsh VK. The impact of the COVID-19 pandemic on referrals to musculoskeletal services from primary care and subsequent incidence of inflammatory rheumatic musculoskeletal disease: an observational study, Rheumatol Adv Pract, 2023;7:rkad044. https://doi.org/10.1093/rap/rkad044.
    3. Wu P, Sharma GV, Mehta LS, Chew-Graham CA, Lundberg GP, Nerenberg KA, Graham MM, Chappell LC, Kadam UT, Jordan KP, Mamas MA. In-hospital complications in pregnancies conceived by assisted reproductive technology. JAHA, 2022;11:e022658. https://doi.org/10.1161/jaha.121.022658.
    4. Wu P, Jordan KP, Chew-Graham CA, Mohamed MO, Barac A, Lundberg GP, Chappell LC, Michos ED, Maas AHEM, Mamas MA. In-hospital complications in pregnant women with current or historical cancer diagnoses. Mayo Clinic Proceedings, 2021;96:2779-2792. https://doi.org/10.1016/j.mayocp.2021.03.038.
    5. Chen Y, Hayward RA, Chew-Graham CA, Hubbard R, Croft P, Sims K, Jordan KP. Prognostic value of first recorded breathlessness for future chronic respiratory and heart disease: a cohort study using UK national primary care database. BJGP, 2020;70:e264-e273. https://doi.org/10.3399/bjgp20x708221.