Abigail Rutter

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Biography

January 2019 – Present: Lecturer in Biomedical Engineering (HEFC Funded)

Current roles include

• School of Pharmacy & Bioengineering Equality, Diversity Inclusion Chair
• School of Pharmacy & Bioengineering Elected Member of Senate
• Regenerative Medicine FReT Membership Co-lead
• Staff-Student liaison officer for MSc Biomed/CTE/MedEng

2016-2019: Postdoctoral Research Associate (Keele University)

Education record

2021: FHEA Fellow of the Higher Education Academy
2012-2016: Ph.D Bioengineering Cancer Studies (Keele University)
2010-2011: MSc Cell and Tissue Engineering (Keele University)
2006-2009: BSc Neuroscience and Psychology (Keele University)

Research and scholarship

Research themes

Regenerative Medicine/Healthcare Technologies

Research interests

My research interests are multidisciplinary; utilising bioengineering, spectrometry and spectroscopy to advance healthcare technologies and understanding. Primary focuses are to move analytical technology and practices to the non-invasive or non-destructive routes.

Scope of interests: Mass spectrometry (SIFT-MS, GC-MS), vibrational spectroscopy (Mid-Infrared FTIR, Synchrotron-FTIR, Raman) preclinical models, supporting technologies, tissue engineering, lungs/Respiratory, ear/nose/throat, stem cell biology, biomarkers, volatile organic compounds, imaging, In vitro modelling, clinical translation, breath analysis, body fluid profiling, cell headspace (the exometabolome).

Current lab group activity

The use of Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) and Vibrational Spectroscopy to profile models of irritable bowel syndromes (IBS), study age related hearing loss (improving basic scientific knowledge, diagnostics and interventions) and investigate the role of cell culture conditions on stem cell metabolic outputs.

Group members

Amy Worrall (PhD Student, 2019-)
Sara Barreto (PhD Student, CDT funded, 2019-)

Teaching

Module lead: MSc Cell & Tissue Engineering (MSc CTE) Cell Biomechanics, BSc Cell & Tissue Engineering (BSc CTE)

Current topics in Regenerative Medicine.

Teaching contributions: MSc CTE; Human Physiology and Anatomy Medical technology projects (Research dissertation projects), Academic Mentor. BSc CTE; Human Physiology and Anatomy, Experimental research methodology. MPharm Stage 4 Final year research projects.

Selected Publications

Barreto S, Al-Zubaidi M, Dale T, Worrall A, Kapacee Z, Kimber S, Sulé-Suso J, Forsyth N, Rutter A. 2022. Physiological Oxygen Causes the Release of Volatile Organic Compounds from Human Pluripotent Stem Cells with Possible Roles in Maintaining Self-Renewal and Pluripotency. doi> full text>
Dowling LM, Roach P, Rutter AV, Yousef I, Pillai S, Latham D, van Pittius DG, Sule-Suso J. 2021. Optimization of Sample Preparation Using Glass Slides for Spectral Pathology. APPLIED SPECTROSCOPY, 343-350, vol. 75(3). link> doi> full text>
Dowling LM, Roach P, Rutter AV, Yousef I, Pillai S, Latham D, van Pittius DG, Sulé-Suso J. 2021. Optimization of Sample Preparation Using Glass Slides for Spectral Pathology. Appl Spectrosc, 343-350, vol. 75(3). link> doi> full text>
Rutter AV, Crees J, Wright H, Raseta M, van Pittius DG, Roach P, Sulé-Suso J. 2020. Identification of a Glass Substrate to Study Cells Using Fourier Transform Infrared Spectroscopy: Are We Closer to Spectral Pathology?. Appl Spectrosc, 178-186, vol. 74(2). link> doi> full text>
Rutter AV, Crees J, Wright H, van Pittius DG, Yousef I, Sulé-Suso J. 2018. Fourier transform infrared spectra of cells on glass coverslips. A further step in spectral pathology. Analyst, 5711-5717, vol. 143(23). link> doi> full text>

Full Publications Listshow

Journal Articles

Barreto S, Al-Zubaidi M, Dale T, Worrall A, Kapacee Z, Kimber S, Sulé-Suso J, Forsyth N, Rutter A. 2022. Physiological Oxygen Causes the Release of Volatile Organic Compounds from Human Pluripotent Stem Cells with Possible Roles in Maintaining Self-Renewal and Pluripotency. doi> full text>
Dowling LM, Roach P, Rutter AV, Yousef I, Pillai S, Latham D, van Pittius DG, Sule-Suso J. 2021. Optimization of Sample Preparation Using Glass Slides for Spectral Pathology. APPLIED SPECTROSCOPY, 343-350, vol. 75(3). link> doi> full text>
Dowling LM, Roach P, Rutter AV, Yousef I, Pillai S, Latham D, van Pittius DG, Sulé-Suso J. 2021. Optimization of Sample Preparation Using Glass Slides for Spectral Pathology. Appl Spectrosc, 343-350, vol. 75(3). link> doi> full text>
Rutter AV, Crees J, Wright H, Raseta M, van Pittius DG, Roach P, Sulé-Suso J. 2020. Identification of a Glass Substrate to Study Cells Using Fourier Transform Infrared Spectroscopy: Are We Closer to Spectral Pathology?. Appl Spectrosc, 178-186, vol. 74(2). link> doi> full text>
Rutter AV, Crees J, Wright H, van Pittius DG, Yousef I, Sulé-Suso J. 2018. Fourier transform infrared spectra of cells on glass coverslips. A further step in spectral pathology. Analyst, 5711-5717, vol. 143(23). link> doi> full text>
Owida HA, Rutter AV, Cinque G, Kuiper NJ, Sulé-Suso J, Yang Y. 2018. Vibrational spectroscopic monitoring and biochemical analysis of pericellular matrix formation and maturation in a 3-dimensional chondrocyte culture model. Analyst, 5979-5986, vol. 143(24). link> doi>
Shestivska V, Rutter AV, Sulé-Suso J, Smith D, Španěl P. 2017. Evaluation of peroxidative stress of cancer cells in vitro by real-time quantification of volatile aldehydes in culture headspace. Rapid Commun Mass Spectrom, 1344-1352, vol. 31(16). link> doi> full text>
Siddique MR, Rutter AV, Wehbe K, Cinque G, Bellisola G, Sulé-Suso J. 2017. Effects of nilotinib on leukaemia cells using vibrational microspectroscopy and cell cloning. Analyst, 1299-1307, vol. 142(8). link> doi> full text>
Rutter AV, Siddique MR, Filik J, Sandt C, Dumas P, Cinque G, Sockalingum GD, Yang Y, Sulé-Suso J. 2014. Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy. Cytometry A, 688-697, vol. 85(8). link> doi>
Pijanka JK, Stone N, Rutter AV, Forsyth N, Sockalingum GD, Yang Y, Sulé-Suso J. 2013. Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation. Analyst, 5052-5058, vol. 138(17). link> doi>
Rutter AV, Chippendale TWE, Yang Y, Španěl P, Smith D, Sulé-Suso J. 2013. Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model. Analyst, 91-95, vol. 138(1). link> doi>
Filik J, Rutter AV, Sulé-Suso J, Cinque G. 2012. Morphological analysis of vibrational hyperspectral imaging data. Analyst. doi>

Chapters

Butcher JB, Rutter AV, Wootton AJ, Day CR, Sule-Suso J. 2018. Artificial Neural Network Analysis of Volatile Organic Compounds for the Detection of Lung Cancer. (vol. 650). link> doi> full text>

Other

Butcher JB, Rutter AV, Wootton AJ, Day CR, Sule-Suso J. 2017. Artificial neural network analysis of volatile organic compounds for the detection of lung cancer. Advances in Intelligent Systems and Computing (pp. 183-190). Springer Verlag. full text>

School address:
School of Pharmacy and Bioengineering
Hornbeam Building
Keele University
Staffordshire
ST5 5BG

Research centre address:
School of Pharmacy and Bioengineering
Guy Hilton Research Centre
Thornburrow Drive
Stoke-on-Trent
ST4 7QB
Tel: +44 (0) 1782 674988

Jack Ashley building accessibility

Undergraduate enquiries:
Email: enquiries@keele.ac.uk
Tel: +44 (0)1782 734010

Postgraduate enquiries:
Please contact the CPD4ALL team:
Email: phab.postgraduate@keele.ac.uk

Keele Centre for Medicines Optimisation (KCMO)
Tel: +44 (0)1782 733831 / 734131

The Virtual Patient project enquiries:
Contact our Digital Development team:
Email: pharmacy.digital@keele.ac.uk

Dr Abigail Rutter (she/her)