Prognosis research projects
Introduction
“To generate high quality evidence regarding the likely future course of a disease or health condition, with the aim to support patients’ and clinicians’ decision-making, improve patient outcomes, and increase efficiency of health care".
Researchers are members and co-founders of the PROGnosis RESearch Strategy (PROGRESS) group.
Clinical Studies
NSAIDs - Trends in Prescribing of NSAIDs in patients with cardiovascular disease (CDVD) between 2002 and 2010.
CAM-PAIN - The Child and Adolescent Musculoskeletal Pain study.
OPIOID ANALGESICS - Risk of adverse events in patients with musculoskeletal pain prescribed long-term.
BREATHLESSNESS SYMPTOMS - The diagnostic and prognostic value of the symptoms of shortness of breath in primary care.
CHEST PAIN IN PRIMARY CARE - Short term trajectories of symptoms and association with long term cardiovascular outcomes.
STAMP - Assessing short term pain trajectories to support prognosis and monitoring of response to treatment in primary care: validity and clinicalutility of a smartphone or tablet application for recording medicines and pain.
CANDID - CANcer DIagnosis Decision rules study.
COPD - Chronic obstructive Pulmonary Disease: Randomised trial and cohort studies.
Methodological Studies
PROG-RES - Prognosis research: A strategic initiative in translational pathways.
OPTIMISING OUTCOME - Prediction in primary care : using longitudinal data in prognosis research.
PREP - Prediction model for Risk of complications in Early onset Pre eclampsia: Development and and validation. A cohort study.
Meta-analyses and systematic reviews
Plantar heel pain and Achilles tendinopathy - Comparative effectiveness oif treatment options : a systematic review and a network meta-analysis.
PROGNOSTIC FACTOR MEASUREMENT - Systematic review of clinical credibility of prognostic models for musculoskeletal pain and disorders in general practice.
MULTIVARIATE META-ANALYSIS - Multiple correlated outcomes: development and application of methods with empirical investigation of clinical impact.
Accuracy of clinical characteristics, biochemical and ultrasound markers in the prediction of pre-eclampsia: Individual Participant Date (IPD) Meta-analysis
QUIDS - Quantitative Fibronectin to help Decision-making in women with Symptoms of Preterm Labour
iWIP - Effects of weight management interventions on maternal and fetal outcomes in pregnancy
Biomarkers for the treatment of cancer - Methods for Evaluating Predictive Biomarkers: Systematic review and methodology research
ROCkETS - Refining Ovarian Cancer Test Accuracy Scores: Systematic review and Individual Participant Data (IPD) analysis.