Dr Jihong Han

Title: Lecturer in Pharmaceutics
Phone: 01782 733834
Email: j.han@keele.ac.uk
Location: Hornbeam Building, Room 1.38
Role: Examinations Officer
Contacting me: by email j.han@keele.ac.uk
Jihong Han

I joined the School of Pharmacy at Keele in 2006 as a lecturer of pharmaceutics. I got my PhD from Nottingham School of Pharmacy in Oct 2000 and worked as a postdoctoral research fellow in Nottingham and London School of Pharmacy. My research interests cover formulation and evaluation of colloidal drug delivery systems (including parenteral emulsions, suspensions, and nanosuspensions). I have also worked on the formulation and stability of paediatric formulations. Other areas include insoluble-carrier supported solid dispersions for improved dissolution and bioavailability of poorly water soluble drugs. Techniques used in my studies include dynamic light scattering, laser diffraction, single particle optical counting, electrical zone sensing, zeta potential analysis, HPLC-MS, PXRD, DSC.

I currently teach some of the pharmaceutics elements in the MPharm programme and facilitate IPE (Inter Professional Education) activities. I am also involved in organising assessment related activities.

I have become a Fellow of the Higher Education Academy since 2011 and obtained a Postgraduate Certificate in Teaching and Learning in Higher Education since 2010.

I am also a Member of the Academic Pharmacy Group of the Royal Pharmaceutical Society of Great Britain (since 2006).

Selected Publications

  • Zong L, Li X, Wang H, Cao Y, Yin L, Li M, Wei Z, Chen D, Pu X, Han J. 2017. Formulation and characterization of biocompatible and stable I.V. itraconazole nanosuspensions stabilized by a new stabilizer polyethylene glycol-poly(β-Benzyl-l-aspartate) (PEG-PBLA). Int J Pharm, vol. 531(1), 108-117. link> doi> full text>
  • Guan J, Han J, Zhang D, Chu C, Liu H, Sun J, He Z, Zhang T. 2014. Increased dissolution rate and oral bioavailability of hydrophobic drug glyburide tablets produced using supercritical CO₂ silica dispersion technology. Eur J Pharm Biopharm, vol. 86(3), 376-382. link> doi>
  • Zhang X, Lu S, Han J, Sun S, Wang L, Li Y. 2011. Preparation, characterization and in vivo distribution of solid lipid nanoparticles loaded with syringopicroside. Die Pharmazie, vol. 66(6), 404-407.
  • Xiaohui P, Sun J, Wang Y, Wang Y, Liu X, Zhang P, Tang X, Pan W, Han J, He Z. 2009. Development of a chemically stable 10-hydroxycamptothecin nanosuspension using microprecipotation-high pressure homogenization. International Journal of Pharmaceutics, vol. 379, 167-173.
  • Han J, Washington C, Davis SS. 2007. Design and evaluation of an emulsion vehicle for paclitaxel. II. Suppression of the crystallization of paclitaxel by freeze-drying technique. Drug Dev Ind Pharm, vol. 33(10), 1151-1157. link> doi>

Full Publications List show

Journal Articles

  • Zong L, Li X, Wang H, Cao Y, Yin L, Li M, Wei Z, Chen D, Pu X, Han J. 2017. Formulation and characterization of biocompatible and stable I.V. itraconazole nanosuspensions stabilized by a new stabilizer polyethylene glycol-poly(β-Benzyl-l-aspartate) (PEG-PBLA). Int J Pharm, vol. 531(1), 108-117. link> doi> full text>
  • Guan J, Han J, Zhang D, Chu C, Liu H, Sun J, He Z, Zhang T. 2014. Increased dissolution rate and oral bioavailability of hydrophobic drug glyburide tablets produced using supercritical CO₂ silica dispersion technology. Eur J Pharm Biopharm, vol. 86(3), 376-382. link> doi>
  • Zhang X, Lu S, Han J, Sun S, Wang L, Li Y. 2011. Preparation, characterization and in vivo distribution of solid lipid nanoparticles loaded with syringopicroside. Die Pharmazie, vol. 66(6), 404-407.
  • Xiaohui P, Sun J, Wang Y, Wang Y, Liu X, Zhang P, Tang X, Pan W, Han J, He Z. 2009. Development of a chemically stable 10-hydroxycamptothecin nanosuspension using microprecipotation-high pressure homogenization. International Journal of Pharmaceutics, vol. 379, 167-173.
  • Han J, Washington C, Davis SS. 2007. Design and evaluation of an emulsion vehicle for paclitaxel. II. Suppression of the crystallization of paclitaxel by freeze-drying technique. Drug Dev Ind Pharm, vol. 33(10), 1151-1157. link> doi>
  • Han J, Beeton A, Long PF, Wong I, Tuleu C. 2006. Physical and microbiological stability of an extemporaneous tacrolimus suspension for paediatric use. J Clin Pharm Ther, vol. 31(2), 167-172. link> doi>
  • Han J, Wang L, Su D. A study of the chemical stability of FT-207 intravenous fat emulsion by HPLC method. Journal of Shenyang Pharmaceutical University, vol. 3(10), 171-175.
  • Zhao N, Liu X, Sun Y, Wang Y, Pu X, Qin Y, Han J, Sun J, He Z. Factors affecting particle size of an intravenous fat emulsions. Asian Journal of Pharmaceutical Sciences, vol. 5(4), 161-167.
  • Han J and Su D. Physical properties of an anticancer drug FT-207 fat emulsion. Journal of Shenyang Pharmaceutical University, vol. 1(8), 14-17.
  • Ning X, Wu Y, Han X, Yan Z, Han J, He Z, Sun J. Strategies to improve dissolution and oral absorption of glimepiride tablets: solid dispersion versus micronization techniques (2011). Drug Development and Industrial Pharmacy, vol. 37, 727-736. doi>
  • Han J and Su D. The properties of the interface between soybean oil and water. Chinese Pharmaceutical Journal, vol. 9(26), 539-542.

Other

  • Panayiotis P, Han J, Davis SS. 2006. Advances in the use of tocols as drug delivery vehicles.
  • Long PF, Han J, Tuleu C, Wong I. 2006. Microbiological Tests on Oral Pediatric Medicines-Requirements for an Improved Pharmacopoeia Monograph.
  • Karimova A, Robertson A, Cross N, Smith L, O'Callaghan M, Tuleu C, Long P, Beeton A, Han J, Ridout D, Goldman A, Brown K. 2005. A wet-primed extracorporeal membrane oxygenation circuit with hollow-fiber membrane oxygenator maintains adequate function for use during cardiopulmonary resusitation after two weeks on standby.
  • Han J, Wong I, Tuleu C. 2005. Extemporaneous tacrolimus suspensions.
  • Tuleu C, Han J, Bingen C, Hardyal G, Shah J, Cope J. 2005. 'In use' stability testing of paediatric CIV AS pre-filled syringes of morphine sulphate in glucose.
  • Han J and Washington C. 2005. Partition of antimicrobial additives in an intraveneous emulsion and their effect on emulsion physical stability. doi>
  • Han J and Tuleu C. 2005. Stability of a sugar-free sidenafil suspension under simulated user sonditions. Neonatal and Paediatric Pharmacists Group Conference.
  • Han J, Melia CD, Washington C. 2004. A concentric cylinder shear device for the study of stability in intraveneous emulsions. doi>
  • Bistrussu S, Beeton A, Castaldo G, Han J, Wong I, Tuleu C, Long P, Brown K, Cross N, Cope J, Goldman AP, Karimova A, O'Callaghan M, Robertson A, Smith L. 2004. Are extracorporeal membrane oxygenation (ECMO) circuits stored 'wet-primed' a likely source of infection?.
  • Han J, Davis SS, Melia CD, Washington C. 2004. Design and evaluation of an emulsion vehicle for paclitaxel. I. Physicochemical properties.
  • Han J, Beeton A, Long P, Karimova A, Robertson A, Cross N, Smith L, O'Callaghan M, Goldman A, Brown K, Tuleu C. 2004. Plasticizer di(2-ethylhexyl)phthalate (DEHP) release in wet-primed extracorporeal membrane oxygenation (ECMO) circuits.
  • Han J, Davis SS, Wash. 2001. Physical properties and stability of two emulsion formulations of propofol. doi>
  • Han J, Davis SS, Washington C. 2000. Comparative physical stability of propofol with EDTA versus sulfite-containing propofol.
  • Han J and Washington C. Adsorption of two model proteins on to emulsions droplets.
  • Davis SS and Han J. Taxol emulsion.