Cumulin in the news


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David Mottershead 2016 200x200
Posted on 24 August 2016
ISTM and School of Pharmacy's Lecturer in Biochemistry & Cell Biology Dr David Mottershead's research on the protein Cumulin has been featured in a wide variety of world media this week, for example: 
David Mottershead joined Keele from the University of Adelaide in January 2016, and his research focuses on two growth factors produced by oocytes which are essential for fertility in mammals.
  •  growth differentiation factor 9 (GDF9) and 
  •  bone morphogenetic factor 15 (BMP15). 
These two proteins are members of the large transforming growth factor beta (TGF-b) family which share structural similarities and mechanisms of action. 
David and colleagues at the University of Adelaide demonstrated a unique mechanism of action critical for signalling by human GDF9, resulting in the production of a new form of the protein which they called Cumulin. Current work is on the molecular mechanisms of action of Cumulin, and investigation of its applications to infertility treatment. 
 
 
 
Full links to quoted media: 
ABC News: http://www.abc.net.au/news/20160824/ invitrotreatmentavoidshormoneinjectionsresearcherssay/7778908
New Scientist: https://www.newscientist.com/article/2102026‐drug‐free‐ivf‐could‐be‐cheaper‐and‐faster‐way‐toget‐pregnant/
International Business Times: http://www.ibtimes.co.uk/potent‐new‐fertility‐technique‐prevents‐side‐effects‐vitro‐fertilisationwomen‐1577610
Daily Mail: http://www.dailymail.co.uk/health/article‐3754639/Fresh‐hope‐childless‐couples‐Scientistsdevelop‐potent‐fertility‐treatment‐cheaper‐IVF‐fewer‐effects.html



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