Publications

  1. Price JP, Levett SJ, Radu V, Simpson DA, Mogas Barcons A, Adams  CF, Mather ML. 2019. Quantum Sensing in a PhysiologicalLike Cell Niche Using Fluorescent Nanodiamonds Embedded in Electrospun Polymer Nanofibers. Small, vol. 15(22). doi> full text>
  2. Adams CF, Jenkins SI. 2019. Nanoengineering neural cells for regenerative medicine. Book chapter: 21st Century Nanoscience. In press
  3. Adams CF, Delaney AM, Carwardine DR, Tickle J, Granger N, Chari DM. 2019. Nanoparticle-Based Imaging of Clinical Transplant Populations Encapsulated in Protective Polymer Matrices. Macromol Biosci, vol. 19(2), e1800389. link> doi> full text>
  4. Jenkins SI and Chari DM. 2018. A Stoichiometrically Defined Neural Coculture Model to Screen Nanoparticles for Neurological Applications. Book chapter: Neuromethods: Nanoparticles in Neuroscience.Santamaria F and Peralta X (Eds.). Humana Press, Inc.. doi> link> full text>
  5. Tickle JA, Poptani H, Taylor A, Chari DM. 2018. Noninvasive imaging of nanoparticle-labeled transplant populations within polymer matrices for neural cell therapy. Nanomedicine (Lond), vol. 13(11), 1333-1348. link> doi>
  6. Al-Mayyahi RS, Sterio LD, Connolly JB, Adams CF, Al-Tumah WA, Sen J, Emes RD, Hart SR, Chari DM. 2018. A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells. Mol Cell Neurosci, vol. 86, 30-40. link> doi> full text>
  7. Adams CF, Sen J, Tickle JA, Tzerakis N, Chari DM. 2017. Developing human dish models of neurological pathology. Midlands Medicine. full text>
  8. Delaney AM, Adams CF, Fernandes AR, Al-Shakli AF, Sen J, Carwardine DR, Granger N, Chari DM. 2017. A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells. Nanoscale, vol. 9(25), 8560-8566. link> doi>
  9. Evans MG, Al-Shakli A, Jenkins SI, Chari DM. 2017. Electrophysiological assessment of primary cortical neurons genetically engineered using iron oxide nanoparticles. NANO RESEARCH, vol. 10(8), 2881-2890. link> doi> full text>
  10. Pickard MR, Adams CF, Chari DM. 2017. Magnetic Nanoparticle-Mediated Gene Delivery to Two- and Three-Dimensional Neural Stem Cell Cultures: Magnet-Assisted Transfection and Multifection Approaches to Enhance Outcomes. Curr Protoc Stem Cell Biol, vol. 40, 2D.19.1-2D.19.16. link> doi> full text>
  11. Adams CF, Dickson AW, Kuiper J-H, Chari DM. 2016. Nanoengineering neural stem cells on biomimetic substrates using magnetofection technology. Nanoscale, vol. 8(41), 17869-17880. link> doi> full text>
  12. Fernandes AR and Chari DM. 2016. Part II: functional delivery of a neurotherapeutic gene to neural stem cells using minicircle DNA and nanoparticles: Translational advantages for regenerative neurology. Journal of Controlled Release. doi> link> full text>
  13. Fernandes AR and Chari DM. 2016. Part I: Minicircle vector technology limits DNA size restrictions on ex vivo gene delivery using nanoparticle vectors: Overcoming a translational barrier in neural stem cell therapy. Journal of Controlled Release. doi> full text>
  14. Adams C, Israel LL, Ostrovsky S, Taylor A, Poptani H, Lellouche J-P, Chari D. 2016. Development of multifunctional magnetic nanoparticles for genetic engineering and tracking of neural stem cells. Adv Healthc Mater, vol. 5(7), 841-849. link> doi>
  15. Tickle J, Jenkins SI, Polyak B, Pickard MR, Chari DM. 2016. Endocytotic potential governs magnetic particle loading in dividing neural cells: Studying modes of particle inheritance. Nanomedicine, vol. 11(4), 348-358. doi> full text>
  16. Jenkins SI, Weinberg D, Al-Shakli AF, Fernandes AR, Yiu HHP, Telling ND, Roach P, Chari DM. 2016. 'Stealth' nanoparticles evade neural immune cells but also evade major brain cell populations: Implications for PEG-based neurotherapeutics. J Control Release, vol. 224, 136-145. link> doi> full text>
  17. Weightman AP, Jenkins SI, Chari DM. 2016. Using a 3-D multicellular simulation of spinal cord injury with live cell imaging to study the neural immune barrier to nanoparticle uptake. Nano Research. doi> link> full text>
  18. Weinberg D, Adams CF, Chari DM. 2015. Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures. RSC ADVANCES, vol. 5(54), 43353-43360. link> doi> full text>
  19. Pickard MR, Adams CF, Barraud P, Chari DM. 2015. Using magnetic nanoparticles for gene transfer to neural stem cells: Stem cell propagation method influences outcomes. J Funct Biomater, vol. 6(2), 259-276. link> doi> full text>
  20. Jenkins SI, Roach P, Chari DM. 2015. Development of a nanomaterial bio-screening platform for neurological applications. Nanomedicine, vol. 11(1), 77-87. link> doi> full text>
  21. Fernandes AR, Adams CF, Furness DN, Chari DM. 2015. Early membrane responses to magnetic particles are predictors of particle uptake in neural stem cells. PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, vol. 32(6), 661-667. link> doi>
  22. Adams CF, Rai A, Sneddon G, Yiu HHP, Polyak B, Chari DM. 2015. Increasing magnetite contents of polymeric magnetic particles dramatically improves labeling of neural stem cell transplant populations. Nanomedicine, vol. 11(1), 19-29. link> doi>
  23. Jenkins SI, Yiu HHP, Rosseinsky MJ, Chari DM. 2014. Magnetic nanoparticles for oligodendrocyte precursor cell transplantation therapies: progress and challenges. Mol Cell Ther, vol. 2, 23. link> doi> full text>
  24. Fernandes AR and Chari DM. 2014. A multicellular, neuro-mimetic model to study nanoparticle uptake in cells of the central nervous system. Integr Biol (Camb), vol. 6(9), 855-861. link> doi>
  25. Tickle JA, Jenkins SI, Pickard MR, Chari DM. 2014. Influence of amplitude of oscillating magnetic fields on magnetic nanoparticle-mediated gene transfer to astrocytes. NanoLife. doi>
  26. Chari DM. 2014. How do corticosteroids influence myelin genesis in the central nervous system?. Neural Regen Res, vol. 9(9), 909-911. link> doi>
  27. Chari DM and Hider S. 2014. Developing the Keele Medical Research Pathway: Challenges For a Young Medical School. Midlands Medicine, vol. 27(3), 140.
  28. Jenkins SI, Pickard MR, Khong M, Smith HL, Mann CLA, Emes RD, Chari DM. 2014. Identifying the cellular targets of drug action in the central nervous system following corticosteroid therapy. ACS Chem Neurosci, vol. 5(1), 51-63. link> doi> full text>
  29. Weightman AP, Pickard MR, Yang Y, Chari DM. 2014. An in vitro spinal cord injury model to screen neuroregenerative materials. Also see News and Views: Spinal cord injury model (Feature on the screening model developed by Chari laboratory). 2014. Alternatives To Laboratory Animals (ATLA; published by Fund For Reduction of Animals in Medical Experiments; FRAME). 42: 1. Biomaterials, vol. 35(12), 3756-3765. link> doi>
  30. Weightman AP, Jenkins SI, Pickard MR, Chari DM, Yang Y. 2014. Alignment of multiple glial cell populations in 3D nanofiber scaffolds: toward the development of multicellular implantable scaffolds for repair of neural injury. Image featured on MRC forum Biomedical Picture of the Day (BPoD) in Nanobiotechnology Week http://bpod.mrc.ac.uk/archive/2014/4/4. Nanomedicine: Nanotechnology, Biology and Medicine, vol. 2(10), 291-295. doi>
  31. Adams CF, Pickard MR, Chari DM. 2013. Magnetic nanoparticle mediated transfection of neural stem cell suspension cultures is enhanced by applied oscillating magnetic fields. Nanomedicine-Nanotechnology Biology And Medicine, vol. 9(6), 737-741. link> doi>
  32. Jenkins SI, Pickard MR, Furness DN, Yiu HHP, Chari DM. 2013. Differences in magnetic particle uptake by CNS neuroglial subclasses: implications for neural tissue engineering. Nanomedicine (Lond), vol. 8(6), 951-968. link> doi> full text>
  33. Jenkins SI, Pickard MR, Chari DM. 2012. Magnetic nanoparticle mediated gene delivery in oligodendroglial cells: a comparison of differentiated versus precursor forms. NanoLIFE, vol. 3(1243001).
  34. Weightman A, Pickard M, Jenkins S, Chari D, Yang Y. 2012. Development of 3D co-culture of aligned glial cells in nanofibre scaffolds for implantation into neural injury sites. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, vol. 6, 88-89. link>
  35. Yiu HH, Pickard MR, Olariu CI, Williams SR, Chari DM, Rosseinsky MJ. 2012. Fe3O4-PEI-RITC magnetic nanoparticles with imaging and gene transfer capability: development of a tool for neural cell transplantation therapies. Also see Putting the Nanoscience in Neuroscience: Magnetic attraction (Feature on research in the Chari laboratory).2012. British Neuroscience Association Bulletin. Issue no 66, p12. http://www.bna.org.uk/about/bna-bulletin.html. Pharm Res, vol. 29(5), 1328-1343. link> doi>
  36. Jenkins SI, Pickard MR, Granger N, Chari DM. 2011. Magnetic nanoparticle-mediated gene transfer to oligodendrocyte precursor cell transplant populations is enhanced by magnetofection strategies. ACS Nano, vol. 5(8), 6527-6538. link> doi>
  37. Chari DM. Transcriptional effects of corticosteroid therapy on myelin genesis and neuronal health. Midlands Medicine. Midlands Medicine, vol. 26(3).
  38. Pickard MR, Barraud P, Chari DM. 2011. The transfection of multipotent neural precursor/stem cell transplant populations with magnetic nanoparticles. Biomaterials, vol. 32(9), 2274-2284. link> doi>
  39. Pickard MR, Jenkins SI, Koller CJ, Furness DN, Chari DM. 2011. Magnetic nanoparticle labeling of astrocytes derived for neural transplantation. Tissue Eng Part C Methods, vol. 17(1), 89-99. link> doi>
  40. Pickard MR and Chari DM. 2010. Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations. Int J Mol Sci, vol. 11(3), 967-981. link> doi> full text>
  41. Pickard M and Chari DM. 2010. Enhancement of magnetic nanoparticle-mediated gene transfer to astrocytes by `magnetofection': effects of static and oscillating fields. Nanomedicine, vol. 5(2), 217-232. doi>
  42. Pickard M and Chari D. 2010. Enhancement of magnetic nanoparticle-mediated gene transfer to astrocytes by 'magnetofection': effects of static and oscillating fields. Nanomedicine (Lond), vol. 5(2), 217-232. link> doi>
  43. Jeffery ND, McBain SC, Dobson J, Chari DM. 2009. Uptake of systemically administered magnetic nanoparticles (MNPs) in areas of experimental spinal cord injury (SCI). J Tissue Eng Regen Med, vol. 3(2), 153-157. link> doi>
  44. Chari DM. 2007. Remyelination in multiple sclerosis. Int Rev Neurobiol, vol. 79, 589-620. link> doi>
  45. CHARI DM, Blakemore WF, Kotter MR, Zhao C. 2006. Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system. Journal of Neuroscience Research, vol. 83(4), 594-605. doi>
  46. Chari DM, Gilson JM, Franklin RJM, Blakemore WF. 2006. Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS. Exp Neurol, vol. 198(1), 145-153. link> doi>
  47. Chari DM, Huang WL, Blakemore WF. 2003. Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue. J Neurosci Res, vol. 73(6), 787-793. link> doi>
  48. CHARI DM, Blakemore WF, Crang AJ. 2003. Decline in rate of colonisation of Oligodendrocyte progenitor cell (OPC) depleted tissue by adult OPCs with age. J Neuropath Exp Neurol, vol. 62(9), 908-916. link> doi>
  49. Chari DM, Huang WL, Blakemore WF. 2003. Repopulation of oligodendrocyte progenitor cell (OPC) depleted areas may be inhibited by the presence of a dysfunctional OPC population in depleted areas. Neuroscience Research, vol. 73, 787-793.
  50. Chari DM and Blakemore WF. 2002. New insights into remyelination failure in multiple sclerosis: implications for glial cell transplantation. Mult Scler, vol. 8(4), 271-277. link> doi>
  51. Blakemore WF, Chari DM, Gilson JM, Crang AJ. 2002. Modelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS. Glia, vol. 38(2), 155-168. link> doi>
  52. Chari DM and Blakemore WF. 2002. Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cells. Glia, vol. 37(4), 307-313. link> doi>
  53. Hinks GL, Chari DM, O'Leary MT, Zhao C, Keirstead HS, Blakemore WF, Franklin RJ. 2001. Depletion of endogenous oligodendrocyte progenitors rather than increased availability of survival factors is a likely explanation for enhanced survival of transplanted oligodendrocyte progenitors in X-irradiated compared to normal CNS. Neuropathol Appl Neurobiol, vol. 27(1), 59-67. link> doi>
Top 10 CUG Top 5 Guardian Athena SWAN