Lorna Clarson

Biography

I gained my MBChB from Sheffield University in 2005. I did my foundation training at the University Hospital of North Staffordshire and Stafford General Hospital. I then completed my General Practice training on the North Staffs Vocational Training Scheme in 2011, completing my Masters of Medical Science at the Arthritis Research UK Primary Care Centre, Keele University, alongside my clinical training. I was awarded my PhD by Keele University in 2015 after investigating the association between gout and vascular disease using electronic health records from the Clinical Practice Research Datalink. I continue to work as a practicing GP in North Staffordshire and as part of the Inflammatory Research Group at the Research Institute for Primary Care and Health Sciences.

Research and scholarship

I have used a variety of research methods in my research career thus far. My MMedSci dissertation reported the analysis of a cross-sectional survey of general practitioners eliciting their views on the monitoring of osteoarthritis and whether OA should be added to the Quality and Outcomes Framework of the General Practice Contract. My PhD research used survival analysis to examine the association between gout and incidence cardiovascular, cerebrovascular and peripheral vascular disease in a large dataset of primary care electronic health records from the Clinical Practice Research Datalink. My ongoing research continues to investigate the association between a variety of systemic inflammatory diseases and adverse outcomes using data from the CPRD.

Teaching

I am the course lead for the Year 3 SSC entitled Research: What every doctor needs to know. I also teach on the Year 3 Public Health Modules.

Selected Publications

Kwok CS, Seferovic PM, Van Spall HG, Helliwell T, Clarson L, Lawson C, Kontopantelis E, Patwala A, Duckett S, Fung E, Mallen CD, Mamas MA. 2019. Early Unplanned Readmissions After Admission to Hospital With Heart Failure. Am J Cardiol, vol. 124(5), 736-745. link> doi> full text>
Sultan AA, Muller S, Whittle R, Roddy E, Mallen C, Clarson L. 2019. Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy. CMAJ, vol. 191(22), E597-E603. link> doi>
Welsh VK, Clarson LE, Mallen CD, McBeth J. 2019. Multisite pain and self-reported falls in older people: systematic review and meta-analysis. Arthritis Res Ther, vol. 21(1), 67. link> doi> full text>
Roughley M, Sultan AA, Clarson L, Muller S, Whittle R, Belcher J, Mallen CD, Roddy E. 2018. Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study. Arthritis Res Ther, vol. 20(1), 243. link> doi> full text>
Crowley L, Sultan AA, Roddy E, Mallen C, Protheroe J, Clarson L. 2018. Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study. ARTHRITIS & RHEUMATOLOGY (vol. 70). link>

Full Publications List show

Journal Articles

Kwok CS, Seferovic PM, Van Spall HG, Helliwell T, Clarson L, Lawson C, Kontopantelis E, Patwala A, Duckett S, Fung E, Mallen CD, Mamas MA. 2019. Early Unplanned Readmissions After Admission to Hospital With Heart Failure. Am J Cardiol, vol. 124(5), 736-745. link> doi> full text>
Sultan AA, Muller S, Whittle R, Roddy E, Mallen C, Clarson L. 2019. Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy. CMAJ, vol. 191(22), E597-E603. link> doi>
Welsh VK, Clarson LE, Mallen CD, McBeth J. 2019. Multisite pain and self-reported falls in older people: systematic review and meta-analysis. Arthritis Res Ther, vol. 21(1), 67. link> doi> full text>
Roughley M, Sultan AA, Clarson L, Muller S, Whittle R, Belcher J, Mallen CD, Roddy E. 2018. Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study. Arthritis Res Ther, vol. 20(1), 243. link> doi> full text>
Clarson LE, Hider SL, Belcher J, Roddy E, Mallen CD. 2017. Factors Influencing Allopurinol Initiation in Primary Care. Ann Fam Med, vol. 15(6), 557-560. link> doi>
Clarson LE, Nicholl BI, Bishop A, Daniel R, Mallen CD. 2016. Discussing prognosis with patients with osteoarthritis: a cross-sectional survey in general practice. Clin Rheumatol, vol. 35(4), 1011-1017. link> doi> full text>
Clarson LE, Hider SL, Belcher J, Heneghan C, Roddy E, Mallen CD. 2015. Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Ann Rheum Dis, vol. 74(4), 642-647. link> doi> full text>
Clarson LE, Chandratre P, Hider SL, Belcher J, Heneghan C, Roddy E, Mallen CD. 2015. Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis. Eur J Prev Cardiol, vol. 22(3), 335-343. link> doi> full text>
Clarson L, Hider SL, Belcher J, Heneghan C, Roddy E, Mallen CD. 2015. Response to: 'Risk of vascular disease with gout: overadjustment of the statistical analyses?' by van Durme et al. Ann Rheum Dis, vol. 74(1), e10. link> doi>
Clarson LE, Nicholl BL, Bishop A, Edwards JJ, Daniel R, Mallen CD. Monitoring Osteoarthritis: A cross sectional survey in general practice (in press). Journal of Clinical Rheumatology. doi>
Chandratre P, Roddy E, Clarson L, Richardson J, Hider SL, Mallen CD. 2013. Health-related quality of life in gout: a systematic review. RHEUMATOLOGY, vol. 52(11), 2031-2040. link> doi>
Clarson LE, Nicholl BI, Bishop A, Edwards J, Daniel R, Mallen C. 2013. Should there be a Quality and Outcomes Framework domain for osteoarthritis? A cross-sectional survey in general practice. Qual Prim Care, vol. 21(2), 97-103. link>

Other

Crowley L, Sultan AA, Roddy E, Mallen C, Protheroe J, Clarson L. 2018. Risk of Dementia in Patients with Gout and the Impact of Urate-Lowering Therapies: A Large Population-Based Cohort Study. ARTHRITIS & RHEUMATOLOGY (vol. 70). link>
Clarson LE, Hider SL, Belcher J, Roddy E, Heneghan C, Mallen CD. 2015. GOUT AND RISK OF SUBSEQUENT VASCULAR EVENT: A DISCRETE-TIME EVENT HISTORY ANALYSIS IN THE CLINICAL PRACTICE RESEARCH DATALINK. RHEUMATOLOGY (vol. 54, p. 38). link> doi>
Clarson LE, Hider SL, Belcher J, Heneghan C, Roddy E, Mallen CD. 2013. GOUT IS AN INDEPENDENT RISK FACTOR FOR ALL TYPES OF VASCULAR DISEASE: A RETROSPECTIVE COHORT STUDY IN THE UK GENERAL PRACTICE RESEARCH DATABASE. RHEUMATOLOGY (vol. 52, pp. 38-39). link>
Chandratre P, Roddy E, Clarson L, Richardson J, Hider SL, Mallen CD. 2013. Health-related quality of life in gout: a systematic review. Rheumatology (Oxford) (vol. 52, pp. 2031-2040). link> doi>

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Dr Lorna Clarson