Jonathan Wastling

Biography

Professor Jonathan Wastling took up his position as Pro Vice-Chancellor and Executive Dean for Natural Sciences in March 2015 after moving from the University of Liverpool. As well as taking overall responsibility for Natural Sciences http://www.keele.ac.uk/natsci/ he has a University-wide brief for postgraduate studies and is Director of the Institute of Liberal Arts and Sciences (ILAS) http://www.keele.ac.uk/ilas/ , a cross-campus Institute committed to promoting interdisciplinary working and advanced studies.

As Executive Dean for Natural Sciences he leads a Faculty focused on delivering high quality research and teaching, with 8 of the Faculty’s 10 teaching disciplines ranked in the top ten and three rated number one in the 2015 National Students Satisfaction Survey. Professor Wastling continues an active research portfolio in host-pathogen biology and is currently funded by BBSRC. He is the author of over 100 peer reviewed scientific publications and 8 book chapters in the area of zoonotic infections and emerging infectious disease, spanning work on Cryptosporidium parasites and the Ebola virus.

Professor Wastling holds a joint Honours BSc in Chemistry and Biology from Keele University and a PhD from the University of Aberdeen. He began his career as a Government Scientist at the Moredun Research Institute, Edinburgh, were he worked on the development of novel vaccines for farm animals, before moving as a Research Fellow to the Faculty of Veterinary Medicine at the University of Edinburgh. In 1995 he was awarded a Personal Research Fellowship by the Royal Society of Edinburgh to work at the Centre for Tropical Veterinary Medicine, later taking his Fellowship to the University of Glasgow where he developed pioneering technologies to help understand fundamental mechanisms of host-pathogen interactions. In 2004 he joined the Faculty of Veterinary Science at Liverpool University where he was appointed to a Personal Chair in 2008, taking up the position of Head of the Department of Veterinary Preclinical Science. In 2011 Professor Wastling became Head of the Department of Infection Biology in the newly formed Institute for Infection and Global Health, leading the development of a new department with an international reputation in veterinary infectious disease.

Professor Wastling is a member of BBSRC’s Agriculture and Food Security Strategic Advisory Panel, advising on aspects of animal health, welfare and food security and is an Editor of Parasitology. He also has a strong interest in the role of higher education in international development, serving for six years as a Government appointed Commissioner at the UK Commonwealth Scholarship Commission and as Chair of Awards Policy.

Selected Publications

Khan A, Fujita AW, Randle N, Regidor-Cerrillo J, Shaik JS, Shen K, Oler AJ, Quinones M, Latham SM, Akanmori BD, Cleaveland S, Innes EA, Ryan U, Šlapeta J, Schares G, Ortega-Mora LM, Dubey JP, Wastling JM, Grigg ME. 2019. Global selective sweep of a highly inbred genome of the cattle parasite Neospora caninum. Proc Natl Acad Sci U S A, vol. 116(45), 22764-22773. link> doi>
Luu L, Johnston LJ, Derricott H, Armstrong SD, Randle N, Hartley CS, Duckworth CA, Campbell BJ, Wastling JM, Coombes JL. 2019. An Open-Format Enteroid Culture System for Interrogation of Interactions Between Toxoplasma gondii and the Intestinal Epithelium. Front Cell Infect Microbiol, vol. 9, 300. link> doi> full text>
Shukla A, Olszewski KL, Llinas M, Rommereim LM, Fox BA, Bzik DJ, Xia D, Wastling J, Beiting D, Roos DS, Shanmugam D. 2018. Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii. International Journal for Parasitology, vol. 48(12), 955-968. link> doi>
Derricott H, Luu L, Fong WY, Hartley CS, Johnston LJ, Armstrong SD, Randle N, Duckworth CA, Campbell BJ, Wastling JM, Coombes JL. 2019. Developing a 3D intestinal epithelium model for livestock species. Cell Tissue Res, vol. 375(2), 409-424. link> doi> full text>
Luu L, Matthews ZJ, Armstrong SD, Powell PP, Wileman T, Wastling JM, Coombes JL. 2018. Proteomic Profiling of Enteroid Cultures Skewed toward Development of Specific Epithelial Lineages. Proteomics, vol. 18(16), e1800132. link> doi> full text>

Full Publications List show

Journal Articles

Khan A, Fujita AW, Randle N, Regidor-Cerrillo J, Shaik JS, Shen K, Oler AJ, Quinones M, Latham SM, Akanmori BD, Cleaveland S, Innes EA, Ryan U, Šlapeta J, Schares G, Ortega-Mora LM, Dubey JP, Wastling JM, Grigg ME. 2019. Global selective sweep of a highly inbred genome of the cattle parasite Neospora caninum. Proc Natl Acad Sci U S A, vol. 116(45), 22764-22773. link> doi>
Luu L, Johnston LJ, Derricott H, Armstrong SD, Randle N, Hartley CS, Duckworth CA, Campbell BJ, Wastling JM, Coombes JL. 2019. An Open-Format Enteroid Culture System for Interrogation of Interactions Between Toxoplasma gondii and the Intestinal Epithelium. Front Cell Infect Microbiol, vol. 9, 300. link> doi> full text>
Shukla A, Olszewski KL, Llinas M, Rommereim LM, Fox BA, Bzik DJ, Xia D, Wastling J, Beiting D, Roos DS, Shanmugam D. 2018. Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii. International Journal for Parasitology, vol. 48(12), 955-968. link> doi>
Derricott H, Luu L, Fong WY, Hartley CS, Johnston LJ, Armstrong SD, Randle N, Duckworth CA, Campbell BJ, Wastling JM, Coombes JL. 2019. Developing a 3D intestinal epithelium model for livestock species. Cell Tissue Res, vol. 375(2), 409-424. link> doi> full text>
Luu L, Matthews ZJ, Armstrong SD, Powell PP, Wileman T, Wastling JM, Coombes JL. 2018. Proteomic Profiling of Enteroid Cultures Skewed toward Development of Specific Epithelial Lineages. Proteomics, vol. 18(16), e1800132. link> doi> full text>
Dubourg A, Xia D, Winpenny JP, Al Naimi S, Bouzid M, Sexton DW, Wastling JM, Hunter PR, Tyler KM. 2018. Giardia secretome highlights secreted tenascins as a key component of pathogenesis. Gigascience, vol. 7(3), 1-13. link> doi> full text>
Horcajo P, Xia D, Randle N, Collantes-Fernández E, Wastling J, Ortega-Mora LM, Regidor-Cerrillo J. 2018. Integrative transcriptome and proteome analyses define marked differences between Neospora caninum isolates throughout the tachyzoite lytic cycle. J Proteomics, vol. 180, 108-119. link> doi> full text>
Al-Bajalan MMM, Xia D, Armstrong S, Randle N, Wastling JM. 2017. Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites. Parasitol Res, vol. 116(10), 2707-2719. link> doi> full text>
Armstrong SD, Xia D, Bah GS, Krishna R, Ngangyung HF, LaCourse EJ, McSorley HJ, Kengne-Ouafo JA, Chounna-Ndongmo PW, Wanji S, Enyong PA, Taylor DW, Blaxter ML, Wastling JM, Tanya VN, Makepeace BL. 2016. Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle. Mol Cell Proteomics, vol. 15(8), 2554-2575. link> doi> full text>
Borgdorff H, Gautam R, Armstrong SD, Xia D, Ndayisaba GF, van Teijlingen NH, Geijtenbeek TB, Wastling JM, van de Wijgert JH. 2016. Cervicovaginal microbiome dysbiosis is associated with proteome changes related to alterations of the cervicovaginal mucosal barrier. Mucosal immunology, vol. 9(3), 621-633. doi> link> full text>
Borgdorff H, Armstrong SD, Tytgat HLP, Xia D, Ndayisaba GF, Wastling JM, van de Wijgert JHHM. 2016. Unique Insights in the Cervicovaginal Lactobacillus iners and L. crispatus Proteomes and Their Associations with Microbiota Dysbiosis. PLoS One, vol. 11(3), e0150767. link> doi> link> full text>
Hunt VL, Tsai IJ, Coghlan A, Reid AJ, Holroyd N, Foth BJ, Tracey A, Cotton JA, Stanley EJ, Beasley H, Bennett HM, Brooks K, Harsha B, Kajitani R, Kulkarni A, Harbecke D, Nagayasu E, Nichol S, Ogura Y, Quail MA, Randle N, Xia D, Brattig NW, Soblik H, Ribeiro DM, Sanchez-Flores A, Hayashi T, Itoh T, Denver DR, Grant W, Stoltzfus JD, Lok JB, Murayama H, Wastling J, Streit A, Kikuchi T, Viney M, Berriman M. 2016. The genomic basis of parasitism in the Strongyloides clade of nematodes. Nature Genetics, vol. 48(3), 299-307. link> doi> full text>
Wang K, Peng ED, Huang AS, Xia D, Vermont SJ, Lentini G, Lebrun M, Wastling JM, Bradley PJ. 2016. Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography. PLoS One, vol. 11(3), e0150561. link> doi> full text>
Dent SD, Xia D, Wastling JM, Neuman BW, Britton P, Maier HJ. 2015. The proteome of the infectious bronchitis virus Beau-R virion. Journal of General Virology, vol. 96(12), 3499-3506. link> doi> link> full text>
Jackson AP, Otto TD, Aslett M, Armstrong SD, Bringaud F, Schlacht A, Hartley C, Sanders M, Wastling JM, Dacks JB, Acosta-Serrano A, Field MC, Ginger ML, Berriman M. 2015. Kinetoplastid Phylogenomics Reveals the Evolutionary Innovations Associated with the Origins of Parasitism. CURRENT BIOLOGY, vol. 26(2), 161-172. link> doi> link> full text>
Minetti C, Lamden K, Durband C, Cheesbrough J, Platt K, Charlett A, O'Brien SJ, Fox A, Wastling JM. 2015. Case-Control Study of Risk Factors for Sporadic Giardiasis and Parasite Assemblages in North West England. Journal of Clinical Microbiology, vol. 53(10), 3133-3140. link> doi> full text>
Minetti C, Lamden K, Durband C, Cheesbrough J, Fox A, Wastling JM. 2015. Determination of Giardia duodenalis assemblages and multi-locus genotypes in patients with sporadic giardiasis from England. Parasit Vectors, vol. 8, 444. link> doi> full text>
Bond A, Vernon A, Reade S, Mayor A, Minetti C, Wastling J, Lamden K, Probert C. 2015. Investigation of Volatile Organic Compounds Emitted from Faeces for the Diagnosis of Giardiasis. Journal of Gastrointestinal and Liver Diseases, vol. 24(3), 281-286. link> doi> link>
Jackson AP, Goyard S, Xia D, Foth BJ, Sanders M, Wastling JM, Minoprio P, Berriman M. 2015. Global Gene Expression Profiling through the Complete Life Cycle of Trypanosoma vivax. PLoS Neglected Tropical Diseases, vol. 9(8), e0003975. link> doi> full text>
Krishna R, Xia D, Sanderson S, Shanmugasundram A, Vermont S, Bernal A, Daniel-Naguib G, Ghali F, Brunk BP, Roos DS, Wastling JM, Jones AR. 2015. A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum. Proteomics, vol. 15(15), 2618-2628. link> doi> full text>
Ramaprasad A, Mourier T, Naeem R, Malas TB, Moussa E, Panigrahi A, Vermont SJ, Otto TD, Wastling J, Pain A. 2015. Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features. PLoS ONE, vol. 10(4), e0124473. link> doi> link> full text>
Ghali F, Krishna R, Perkins S, Collins A, Xia D, Wastling J, Jones AR. 2014. ProteoAnnotator--open source proteogenomics annotation software supporting PSI standards. Proteomics, vol. 14(23-24), 2731-2741. link> doi> full text>
García-Dorival I, Wu W, Dowall S, Armstrong S, Touzelet O, Wastling J, Barr JN, Matthews D, Carroll M, Hewson R, Hiscox JA. 2014. Elucidation of the Ebola virus VP24 cellular interactome and disruption of virus biology through targeted inhibition of host-cell protein function. Journal of Proteome Research, vol. 13(11), 5120-5135. link> doi> full text>
Minetti C, Taweenan W, Hogg R, Featherstone C, Randle N, Latham SM, Wastling JM. 2014. Occurrence and diversity of Giardia duodenalis assemblages in livestock in the UK. Transboundary and Emerging Diseases, vol. 61(6), e60-e67. link> doi> link> full text>
Armstrong SD, Babayan SA, Lhermitte-Vallarino N, Gray N, Xia D, Martin C, Kumar S, Taylor DW, Blaxter ML, Wastling JM, Makepeace BL. 2014. Comparative analysis of the secretome from a model filarial nematode (Litomosoides sigmodontis) reveals maximal diversity in gravid female parasites. Molecular and Cellular Proteomics, vol. 13(10), 2527-2544. link> doi>
Wiens O, Xia D, von Schubert C, Wastling JM, Dobbelaere DAE, Heussler VT, Woods KL. 2014. Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins. PLoS One, vol. 9(7), e103821. link> doi> full text>
Burniston JG, Kenyani J, Gray D, Guadagnin E, Jarman IH, Cobley JN, Cuthbertson DJ, Chen Y-W, Wastling JM, Lisboa PJ, Koch LG, Britton SL. 2014. Conditional independence mapping of DIGE data reveals PDIA3 protein species as key nodes associated with muscle aerobic capacity. Journal of Proteomics, vol. 106, 230-245. link> doi> link> full text>
Jackson AP, Otto TD, Darby A, Ramaprasad A, Xia D, Echaide IE, Farber M, Gahlot S, Gamble J, Gupta D, Gupta Y, Jackson L, Malandrin L, Malas TB, Moussa E, Nair M, Reid AJ, Sanders M, Sharma J, Tracey A, Quail MA, Weir W, Wastling JM, Hall N, Willadsen P, Lingelbach K, Shiels B, Tait A, Berriman M, Allred DR, Pain A. 2014. The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction. Nucleic Acids Research, vol. 42(11), 7113-7131. link> doi> link> full text>
Rose C, Belmonte R, Armstrong SD, Molyneux G, Haines LR, Lehane MJ, Wastling J, Acosta-Serrano A. 2014. An investigation into the protein composition of the teneral Glossina morsitans morsitans peritrophic matrix. PLoS Neglected Tropical Diseases, vol. 8(4), e2691. link> doi> link> full text>
Doliwa C, Xia D, Escotte-Binet S, Newsham EL, Sanya J S, Aubert D, Randle N, Wastling JM, Villena I. 2013. Identification of differentially expressed proteins in sulfadiazine resistant and sensitive strains of Toxoplasma gondii using difference-gel electrophoresis (DIGE). International Journal for Parasitology: Drugs and Drug Resistance, vol. 3, 35-44. link> doi> link> full text>
Darby AC, Gill AC, Armstrong SD, Hartley CS, Xia D, Wastling JM, Makepeace BL. 2013. Integrated transcriptomic and proteomic analysis of the global response of Wolbachia to doxycycline-induced stress. ISME Journal, vol. 8(4), 925-937. link> doi> link> full text>
Christley RM, Mort M, Wynne B, Wastling JM, Heathwaite AL, Pickup R, Austin Z, Latham SM. 2013. "Wrong, but useful": negotiating uncertainty in infectious disease modelling. PLoS One, vol. 8(10), e76277. link> doi> full text>
Witschi M, Xia D, Sanderson S, Baumgartner M, Wastling JM, Dobbelaere DAE. 2013. Proteomic analysis of the Theileria annulata schizont. International Journal for Parasitology, vol. 43(2), 173-180. link> doi> link> full text>
Oakes RD, Kurian D, Bromley E, Ward C, Lal K, Blake DP, Reid AJ, Pain A, Sinden RE, Wastling JM, Tomley FM. 2013. The rhoptry proteome of Eimeria tenella sporozoites. International Journal for Parasitology, vol. 43(2), 181-188. link> doi> link>
Shanmugasundram A, Gonzalez-Galarza FF, Wastling JM, Vasieva O, Jones AR. 2012. Library of Apicomplexan Metabolic Pathways: a manually curated database for metabolic pathways of apicomplexan parasites. Nucleic Acids Research, vol. 41(Database issue), D706-D713. link> doi> link> full text>
Darby AC, Armstrong SD, Bah GS, Kaur G, Hughes MA, Kay SM, Koldkjær P, Rainbow L, Radford AD, Blaxter ML, Tanya VN, Trees AJ, Cordaux R, Wastling JM, Makepeace BL. 2012. Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis. Genome Research, vol. 22(12), 2467-2477. link> doi> link> full text>
Wastling JM, Armstrong SD, Krishna R, Xia D. 2012. Parasites, proteomes and systems: has Descartes' clock run out of time?. Parasitology, vol. 139(9), 1103-1118. link> doi> link> full text>
Austin Z, Alcock RE, Christley RM, Haygarth PM, Heathwaite AL, Latham SM, Mort M, Oliver DM, Pickup R, Wastling JM, Wynne B. 2012. Policy, practice and decision making for zoonotic disease management: water and Cryptosporidium. Environ Int, vol. 40, 70-78. link> doi>
Reid AJ, Vermont SJ, Cotton JA, Harris D, Hill-Cawthorne GA, Könen-Waisman S, Latham SM, Mourier T, Norton R, Quail MA, Sanders M, Shanmugam D, Sohal A, Wasmuth JD, Brunk B, Grigg ME, Howard JC, Parkinson J, Roos DS, Trees AJ, Berriman M, Pain A, Wastling JM. 2012. Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy. PLoS Pathog, vol. 8(3), e1002567. link> doi> full text>
Burniston JG, Kenyani J, Wastling JM, Burant CF, Qi NR, Koch LG, Britton SL. 2011. Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity. Proteomics, vol. 11(16), 3369-3379. link> doi>
Fish R, Austin Z, Christley R, Haygarth PM, Heathwaite AL, Latham S, Medd W, Mort M, Oliver DM, Pickup R, Wastling JM, Wynne B. 2011. Uncertainties in the governance of animal disease: an interdisciplinary framework for analysis. Philos Trans R Soc Lond B Biol Sci, vol. 366(1573), 2023-2034. link> doi>
Sohn CS, Cheng TT, Drummond ML, Peng ED, Vermont SJ, Xia D, Cheng SJ, Wastling JM, Bradley PJ. 2011. Identification of novel proteins in Neospora caninum using an organelle purification and monoclonal antibody approach. PLoS One, vol. 6(4), e18383. link> doi> full text>
Kenyani J, Medina-Aunon JA, Martinez-Bartolomé S, Albar J-P, Wastling JM, Jones AR. 2011. A DIGE study on the effects of salbutamol on the rat muscle proteome - an exemplar of best practice for data sharing in proteomics. BMC Res Notes, vol. 4, 86. link> doi> full text>
Barlow AM, Mullineaux E, Wood R, Taweenan W, Wastling JM. 2010. Giardiosis in Eurasian badgers (Meles meles). Vet Rec, vol. 167(26), 1017. link> doi>
Bridge JW, Oliver DM, Chadwick D, Godfray HCJ, Heathwaite AL, Kay D, Maheswaran R, McGonigle DF, Nichols G, Pickup R, Porter J, Wastling J, Banwart SA. 2010. Engaging with the water sector for public health benefits: waterborne pathogens and diseases in developed countries. Bull World Health Organ, vol. 88(11), 873-875. link> doi>
Lal K, Bromley E, Oakes R, Prieto JH, Sanderson SJ, Kurian D, Hunt L, Yates JR, Wastling JM, Sinden RE, Tomley FM. 2009. Proteomic comparison of four Eimeria tenella life-cycle stages: unsporulated oocyst, sporulated oocyst, sporozoite and second-generation merozoite. Proteomics, vol. 9(19), 4566-4576. link> doi>
Siddiki AMAMZ and Wastling JM. 2009. Charting the proteome of Cryptosporidium parvum sporozoites using sequence similarity-based BLAST searching. J Vet Sci, vol. 10(3), 203-210. link> doi>
Lal K, Delves MJ, Bromley E, Wastling JM, Tomley FM, Sinden RE. 2009. Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development. Int J Parasitol, vol. 39(7), 755-761. link> doi>
Wu Y, Nelson MM, Quaile A, Xia D, Wastling JM, Craig A. 2009. Identification of phosphorylated proteins in erythrocytes infected by the human malaria parasite Plasmodium falciparum. Malar J, vol. 8, 105. link> doi>
Lal K, Prieto JH, Bromley E, Sanderson SJ, Yates JR, Wastling JM, Tomley FM, Sinden RE. 2009. Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome. Proteomics, vol. 9(5), 1142-1151. link> doi>
Wastling JM, Xia D, Sohal A, Chaussepied M, Pain A, Langsley G. 2009. Proteomes and transcriptomes of the Apicomplexa--where's the message?. Int J Parasitol, vol. 39(2), 135-143. link> doi>
Müller J, Sidler D, Nachbur U, Wastling J, Brunner T, Hemphill A. 2008. Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells. Int J Cancer, vol. 123(8), 1797-1806. link> doi>
Sanderson SJ, Xia D, Prieto H, Yates J, Heiges M, Kissinger JC, Bromley E, Lal K, Sinden RE, Tomley F, Wastling JM. 2008. Determining the protein repertoire of Cryptosporidium parvum sporozoites. Proteomics, vol. 8(7), 1398-1414. link> doi>
Nelson MM, Jones AR, Carmen JC, Sinai AP, Burchmore R, Wastling JM. 2008. Modulation of the host cell proteome by the intracellular apicomplexan parasite Toxoplasma gondii. Infect Immun, vol. 76(2), 828-844. link> doi>
Tzannes S, Batchelor DJ, Graham PA, Pinchbeck GL, Wastling J, German AJ. 2008. Prevalence of Cryptosporidium, Giardia and Isospora species infections in pet cats with clinical signs of gastrointestinal disease. J Feline Med Surg, vol. 10(1), 1-8. link> doi>
Batchelor DJ, Tzannes S, Graham PA, Wastling JM, Pinchbeck GL, German AJ. 2008. Detection of endoparasites with zoonotic potential in dogs with gastrointestinal disease in the UK. Transbound Emerg Dis, vol. 55(2), 99-104. link> doi>
Xia D, Sanderson SJ, Jones AR, Prieto JH, Yates JR, Bromley E, Tomley FM, Lal K, Sinden RE, Brunk BP, Roos DS, Wastling JM. 2008. The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation. Genome Biol, vol. 9(7), R116. link> doi> full text>
Müller J, Wastling J, Sanderson S, Müller N, Hemphill A. 2007. A novel Giardia lamblia nitroreductase, GlNR1, interacts with nitazoxanide and other thiazolides. Antimicrob Agents Chemother, vol. 51(6), 1979-1986. link> doi>
Srinivasan S, Baszler T, Vonlaufen N, Leepin A, Sanderson SJ, Wastling JM, Hemphill A. 2006. Monoclonal antibody directed against Neospora caninum tachyzoite carbohydrate epitope reacts specifically with apical complex-associated sialylated beta tubulin. J Parasitol, vol. 92(6), 1235-1243. link> doi>
Foucher AL, McIntosh A, Douce G, Wastling J, Tait A, Turner CMR. 2006. A proteomic analysis of arsenical drug resistance in Trypanosoma brucei. Proteomics, vol. 6(9), 2726-2732. link> doi>
Craig H, Wastling JM, Knox DP. 2006. A preliminary proteomic survey of the in vitro excretory/secretory products of fourth-stage larval and adult Teladorsagia circumcincta. Parasitology, vol. 132(Pt 4), 535-543. link> doi>
Jones A, Faldas A, Foucher A, Hunt E, Tait A, Wastling JM, Turner CM. 2006. Visualisation and analysis of proteomic data from the procyclic form of Trypanosoma brucei. Proteomics, vol. 6(1), 259-267. link> doi>
Bradley PJ, Ward C, Cheng SJ, Alexander DL, Coller S, Coombs GH, Dunn JD, Ferguson DJ, Sanderson SJ, Wastling JM, Boothroyd JC. 2005. Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J Biol Chem, vol. 280(40), 34245-34258. link> doi>
Smith HV, Nichols RAB, Mallon M, Macleod A, Tait A, Reilly WJ, Browning LM, Gray D, Reid SWJ, Wastling JM. 2005. Natural Cryptosporidium hominis infections in Scottish cattle. Vet Rec, vol. 156(22), 710-711. link> doi>
Keller N, Riesen M, Naguleswaran A, Vonlaufen N, Stettler R, Leepin A, Wastling JM, Hemphill A. 2004. Identification and characterization of a Neospora caninum microneme-associated protein (NcMIC4) that exhibits unique lactose-binding properties. Infect Immun, vol. 72(8), 4791-4800. link> doi>
Jones A, Hunt E, Wastling JM, Pizarro A, Stoeckert CJ. 2004. An object model and database for functional genomics. Bioinformatics, vol. 20(10), 1583-1590. link> doi>
Putignani L, Tait A, Smith HV, Horner D, Tovar J, Tetley L, Wastling JM. 2004. Characterization of a mitochondrion-like organelle in Cryptosporidium parvum. Parasitology, vol. 129(Pt 1), 1-18. link> doi>
Shiels BR, McKellar S, Katzer F, Lyons K, Kinnaird J, Ward C, Wastling JM, Swan D. 2004. A Theileria annulata DNA binding protein localized to the host cell nucleus alters the phenotype of a bovine macrophage cell line. Eukaryot Cell, vol. 3(2), 495-505. link> doi>
Mallon ME, MacLeod A, Wastling JM, Smith H, Tait A. 2003. Multilocus genotyping of Cryptosporidium parvum Type 2: population genetics and sub-structuring. Infect Genet Evol, vol. 3(3), 207-218. link> doi>
De Koning HP, Al-Salabi MI, Cohen AM, Coombs GH, Wastling JM. 2003. Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii. Int J Parasitol, vol. 33(8), 821-831. link> doi>
Mallon M, MacLeod A, Wastling J, Smith H, Reilly B, Tait A. 2003. Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum. J Mol Evol, vol. 56(4), 407-417. link> doi>
Wastling JM and Mattsson JG. 2003. Detection of Toxoplasma gondii. Methods Mol Biol, vol. 216, 289-297. link> doi>
Jones A, Wastling J, Hunt E. 2003. Proposal for a standard representation of two-dimensional gel electrophoresis data. Comp Funct Genomics, vol. 4(5), 492-501. link> doi>
Osawa T, Wastling J, Acosta L, Ortellado C, Ibarra J, Innes EA. 2002. Seroprevalence of Neospora caninum infection in dairy and beef cattle in Paraguay. Vet Parasitol, vol. 110(1-2), 17-23. link> doi>
Cohen AM, Rumpel K, Coombs GH, Wastling JM. 2002. Characterisation of global protein expression by two-dimensional electrophoresis and mass spectrometry: proteomics of Toxoplasma gondii. Int J Parasitol, vol. 32(1), 39-51. link> doi>
Schock A, Innes EA, Yamane I, Latham SM, Wastling JM. 2001. Genetic and biological diversity among isolates of Neospora caninum. Parasitology, vol. 123(Pt 1), 13-23. link> doi>
Ferguson DJ and Wastling JM. 2001. T.gondii--a reply. Biologist (London), vol. 48(3), 104. link>
Wastling J, Heap S, Ferguson D. 2000. Toxoplasma gondii--keeping our guests under control. Biologist (London), vol. 47(5), 234-238. link>
van der Puije WN, Bosompem KM, Canacoo EA, Wastling JM, Akanmori BD. 2000. The prevalence of anti-Toxoplasma gondii antibodies in Ghanaian sheep and goats. Acta Trop, vol. 76(1), 21-26. link> doi>
Bisson A, Maley S, Rubaire-Akiiki CM, Wastling JM. 2000. The seroprevalence of antibodies to toxoplasma gondii in domestic goats in Uganda. Acta Trop, vol. 76(1), 33-38. link> doi>
Arko-Mensah J, Bosompem KM, Canacoo EA, Wastling JM, Akanmori BD. 2000. The seroprevalence of toxoplasmosis in pigs in Ghana. Acta Trop, vol. 76(1), 27-31. link> doi>
Williams DJ, Akanmori BD, Wastling JM. 2000. Towards improving control of zoonoses in West Africa. Acta Trop, vol. 76(1), 1-2. link> doi>
Innes EA, Buxton D, Maley S, Wright S, Marks J, Esteban I, Rae A, Schock A, Wastling J. 2000. Neosporosis. Aspects of epidemiology and host immune response. Ann N Y Acad Sci, vol. 916, 93-101. link> doi>
Wastling JM, Akanmori BD, Williams DJ. 1999. Zoonoses in West Africa: impact and control. Parasitol Today, vol. 15(8), 309-311. link> doi>
Trees AJ, Davison HC, Innes EA, Wastling JM. 1999. Towards evaluating the economic impact of bovine neosporosis. Int J Parasitol, vol. 29(8), 1195-1200. link> doi>
McLauchlan PE, Roberts HC, Loxton NJ, Wastling JM, Newlands GF, Chappell LH. 1999. Mucosal mast cell responses and release of mast cell protease-I in infections of mice with Hymenolepis diminuta and H. microstoma: modulation by cyclosporin A. Parasite Immunol, vol. 21(3), 151-161. link> doi>
Osawa T, Wastling J, Maley S, Buxton D, Innes EA. 1998. A multiple antigen ELISA to detect Neospora-specific antibodies in bovine sera, bovine foetal fluids, ovine and caprine sera. Vet Parasitol, vol. 79(1), 19-34. link> doi>
Wastling JM, Knight P, Ure J, Wright S, Thornton EM, Scudamore CL, Mason J, Smith A, Miller HR. 1998. Histochemical and ultrastructural modification of mucosal mast cell granules in parasitized mice lacking the beta-chymase, mouse mast cell protease-1. Am J Pathol, vol. 153(2), 491-504. link> doi>
Wastling JM and Kinnaird JH. 1998. Isolation and characterisation of a genomic clone encoding a cdc2-related kinase of Toxoplasma gondii. Mol Biochem Parasitol, vol. 94(1), 143-148. link> doi>
ABARCA B, MOJARRED F, JONES G, PHILLIPS C, NG N, WASTLING J. 1988. TRIAZOLOPYRIDINES .8. NUCLEOPHILIC-SUBSTITUTION REACTIONS OF 5-BROMO[1,2,3]TRIAZOLO[5,1-A]ISOQUINOLINE AND 7-BROMO[1,2,3]-TRIAZOLO[1,5-A]PYRIDINE. TETRAHEDRON, vol. 44(10), 3005-3014. link>
Wastling JM, Scudamore CL, Thornton EM, Newlands GF, Miller HR. 1997. Constitutive expression of mouse mast cell protease-1 in normal BALB/c mice and its up-regulation during intestinal nematode infection. Immunology, vol. 90(2), 308-313. link> doi>
Innes EA, Panton WR, Sanderson A, Thomson KM, Wastling JM, Maley S, Buxton D. 1995. Induction of CD4+ and CD8+ T cell responses in efferent lymph responding to Toxoplasma gondii infection: analysis of phenotype and function. Parasite Immunol, vol. 17(3), 151-160. link> doi>
Wastling JM, Harkins D, Maley S, Innes E, Panton W, Thomson K, Buxton D. 1995. Kinetics of the local and systemic antibody response to primary and secondary infection with S48 Toxoplasma gondii in sheep. J Comp Pathol, vol. 112(1), 53-62. link> doi>
Wastling JM, Harkins D, Buxton D. 1994. Western blot analysis of the IgG response of sheep vaccinated with S48 Toxoplasma gondii (Toxovax). Res Vet Sci, vol. 57(3), 384-386. link> doi>
Buxton D, Thomson KM, Maley S, Wastling JM, Innes EA, Panton WR, Nicoll S. 1994. Primary and secondary responses of the ovine lymph node to Toxoplasma gondii: cell output in efferent lymph and parasite detection. J Comp Pathol, vol. 111(3), 231-241. link> doi>
Wastling JM and Chappell LH. 1994. Cyclosporin A: drug treatment in vivo affects the kinetics of [14C]glucose transport in Hymenolepis microstoma in vitro. Parasitology, vol. 108 ( Pt 2), 223-228. link> doi>
Oura CA, Innes EA, Wastling JM, Entrican G, Panton WR. 1993. The inhibitory effect of ovine recombinant interferon-gamma on intracellular replication of Toxoplasma gondii. Parasite Immunol, vol. 15(9), 535-538. link> doi>
Wastling JM, Nicoll S, Buxton D. 1993. Comparison of two gene amplification methods for the detection of Toxoplasma gondii in experimentally infected sheep. J Med Microbiol, vol. 38(5), 360-365. link> doi>
Wastling JM, MacKenzie K, Chappell LH. 1992. Effects of cyclosporin A on the morphology and tegumentary ultrastructure of Hymenolepis microstoma in vivo. Parasitology, vol. 104 ( Pt 3), 531-538. link> doi>
Chappell LH and Wastling JM. 1992. Cyclosporin A: antiparasite drug, modulator of the host-parasite relationship and immunosuppressant. Parasitology, vol. 105 Suppl, S25-S40. link> doi>
Wastling JM, Gerrard D, Walker J, Chappell LH. 1990. Action of cyclosporin A on the tapeworm Hymenolepis diminuta in mice. Parasitology, vol. 101 Pt 3, 465-472. link> doi>
Chappell LH, Wastling JM, Hurd H. 1989. Action of cyclosporin A on the tapeworms Hymenolepis microstoma, H. diminuta and Mesocestoides corti in vivo. Parasitology, vol. 98 Pt 2, 291-299. link> doi>

Other

Bond A, Vernon A, Reade S, Mayor A, Wastling J, Minetti C, Lamden K, Probert C. 2015. INVESTIGATION OF VOLATILE ORGANIC COMPOUNDS EMITTED FROM FAECES FOR THE DIAGNOSIS OF GIARDIASIS. GUT (vol. 64, p. A288). BMJ. link> doi>