Using CRISPR/CAS9 to investigate the relationship between genes and human disease.
CRISPR/CAS 9 system is a revolutionary molecular method which can be used to make precise and accurate edits within the human genome. CRISPR continues to be an instrumental technique used in the Department of Biochemistry, within Genomics. Such type of genomic editing has been used to analyse the relationship with gene expression and cardiac abnormalities in newborns. MYBPC3 gene (associated with familial dilated cardiomyopathy), had successfully been altered using CRISPR. This method can be used to examine inherited genetic and degenerative diseases within newborn babies. This paper will review how CRISPR is administered in humans with emphasis on neonatal interventions.