Prof Warren Lenney

Title: Professor of Child Health
Consultant Respiratory Paediatrician
Phone: +44 (0)1782 675289
Email: warren.lenney@uhns.nhs.uk
Location: Institute for Science & Technology in Medicine, Keele University
Guy Hilton Research Centre, Thornburrow Drive, Hartshill Stoke-on-Trent, ST4 7QB United Kingdom
Role: ISTM Research themes: 1. Diagnostic Engineering & Proteomics
2. Health Services Research
Contacting me: By e-mail please.
Prof Warren Lenney

Professor Lenney took up his current post of Consultant Respiratory Paediatrician at the University Hospitals of North Midlands in 1996. For several years he was Associate Medical Director for Research and Development for North Staffordshire and is Chair of the British Paediatric Respiratory Society’s Research Committee.

Prof Lenney lectures widely on paediatric respiratory issues and was awarded a personal Chair at Keele University in 2005.

In 2006 Prof Lenney was appointed Director of the West Midlands Local Research Network for Medicines for Children (MfC).

Previous appointments:

  • Associate Medical Director, Glaxo Pharmaceuticals UK 1993-5
  • Consultant Paediatrician, Royal Alexandra Hospital, Brighton 1981-93
  • Senior Registrar, Royal Alexandra Hospital, Brighton 1978-81
  • Registrar/Research Fellow, Queens Medical Centre, Nottingham 1975-8

ISTM Research themes: 1. Diagnostic Engineering & Proteomics
                                        2. Health Services Research

Current research interests involve the genetics of asthma, surrogate markers of inflammation in children and studies involving the actions and benefits of combination therapy.

Research grants:

1996: £37,000 Impact Study on palivizumab. European representative on the write-up team.
1997: £40,000 Audit of paediatric referrals to A&E NSRI
1998: £20,000
1998: £80,000
Two Centre study of nebulised Fluticasone – efficacy and safety.
1999: £205,000 Glaxo Wellcome: Asthma Genetics Study (2 years)

One of 9 international research centres

1999: £50,000 Further grant from Zeneca Pharmaceuticals to study genetics in pre-school children with asthma. Development of cold air challenge system, body plethysmography and the interrupter technique.
2000: £13,000 Clinical studies; follow-up of preterm babies with chronic lung disease. Four clinical centres in the UK.
2000-2001: £13,000 Multinational study assessing the efficacy of combination therapy in childhood asthma. Lead Investigator.
2001: £58,000 Health Action Zone grant (in association with Dr Charles Pantin) to develop asthma care pathways and audit the results.
2001: £21,000 Stoke Housing Authority project to assess the association of asthma and poor housing conditions.
2003: £50,000 Educational grant to develop studies in childhood asthma and to continue the previous genetic asthma work.
2003: £5,000 North Staffordshire Medical Institute grant to develop SIFT-MS study of pseudomonas infections in cystic fibrosis.
2003: £2,000 Peel Medical Trust Grant to study pseudomonas genotype in cystic fibrosis.
2004: £40,000 Education grant to cover research fellow’s second year (Dr Will Carroll)
2004: £50,000 Educational grant from GlaxoSmithKline to study tachyphylaxis to Salmeterol in children.
2004: £60,000 Educational grant to develop paediatric SIFT-MS in North Staffordshire.
2005: £20,000 Educational grant from Abbott Laboratories for preterm baby follow-up study
2006 £45,000 Educational grant to support SIFT-MS study
2006 £350,000 HTA School aged children with asthma study – outline business case approved. Awaiting result of full business case.
2006 Stoke-on-Trent approved as Local Research Network – Medicines for Children. Infrastructure funding approximately £150,000 / yr
2007: £16,000 Pharmaceutical Profiles Ltd: TOB003 PARI eFlow scinitgraphy study

 

Selected Publications

  • Lenney W, McKay AJ, Tudur Smith C, Williamson PR, James M, Price D, MASCOT Study Group. 2013. Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety. Health Technol Assess, vol. 17(4), 1-218. link> doi>
  • Greenough A, Alexander J, Boit P, Boorman J, Burgess S, Burke A, Chetcuti PA, Cliff I, Lenney W, Lytle T, Morgan C, Raiman C, Shaw NJ, Sylvester KP, Turner J. 2009. School age outcome of hospitalisation with respiratory syncytial virus infection of prematurely born infants. Thorax, vol. 64(6), 490-495. link> doi>
  • Davies G, Paton JY, Beaton SJ, Young D, Lenney W. 2008. Children admitted with acute wheeze/asthma during November 1998-2005: a national UK audit. Arch Dis Child, vol. 93(11), 952-958. link> doi>
  • Zhu G, Whyte MKB, Vestbo J, Carlsen K, Carlsen K-H, Lenney W, Silverman M, Helms P, Pillai SG. 2008. Interleukin 18 receptor 1 gene polymorphisms are associated with asthma. Eur J Hum Genet, vol. 16(9), 1083-1090. link> doi>
  • Lenney W. ESR Taskforce: Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. European Respiratory Journal, 1096-1110. doi>

Full Publications List show

Journal Articles

  • Lenney W, McKay AJ, Tudur Smith C, Williamson PR, James M, Price D, MASCOT Study Group. 2013. Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety. Health Technol Assess, vol. 17(4), 1-218. link> doi>
  • Greenough A, Alexander J, Boit P, Boorman J, Burgess S, Burke A, Chetcuti PA, Cliff I, Lenney W, Lytle T, Morgan C, Raiman C, Shaw NJ, Sylvester KP, Turner J. 2009. School age outcome of hospitalisation with respiratory syncytial virus infection of prematurely born infants. Thorax, vol. 64(6), 490-495. link> doi>
  • Davies G, Paton JY, Beaton SJ, Young D, Lenney W. 2008. Children admitted with acute wheeze/asthma during November 1998-2005: a national UK audit. Arch Dis Child, vol. 93(11), 952-958. link> doi>
  • Zhu G, Whyte MKB, Vestbo J, Carlsen K, Carlsen K-H, Lenney W, Silverman M, Helms P, Pillai SG. 2008. Interleukin 18 receptor 1 gene polymorphisms are associated with asthma. Eur J Hum Genet, vol. 16(9), 1083-1090. link> doi>
  • Lenney W. ESR Taskforce: Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. European Respiratory Journal, 1096-1110. doi>
  • Enderby B, Smith D, Carroll W, Lenney W. Hydrogen cyanide as a biomarker for Pseudomonas aeruginosa in the breath of cchildren with cystic fibrosis. Pediatric Pulmonology, vol. 44(2), 142-147. doi>

Professional memberships, committees, editorial boards:

  • Respiratory Paediatrics (RCPCH) - Specialist Advisory Committee Member
  • Medicines for Children (RCPCH) - Editorial Board
  • North Staffs Drugs and Therapeutics Committee
  • Royal Society of Medicine, Respiratory Division - Council Member
  • British Lung Foundation - Trustee
  • British Thoracic Society -
    - Paediatric member, External Relations Committee
    - Education Committee Member
    - Scientific Meetings Committee Member