Research and scholarship

ISTM Research theme: Therapeutics

Research Interests:

  • Study of how polymorphic genes interact with environmental factors such as ultraviolet radiation to influence susceptibility and outcome in multiple sclerosis, basal cell carcinoma and prostate cancer.
  • Selection of candidate genes, identification of allelic variants and construction of haplotypes. Use of advanced statistics to identify genetic and environmental influences on risk in patient subgroups.
  • Work based on multispeciality teams of biochemists, clinicians and statisticians.

ISTM_Strange_images1+2_650x300  

Research grants:
 

Project Leaders

Funder

Title

Start date

Duration (mths)

Awarded

Monica Spiteri, Richard Strange, Anthony Fryer

 

British Lung Foundation

Is the I1005V polymorphism at the glutathione S-transferase, GSTP1, locus functionally significant in the development of atopic airway inflammation?

01/08/99

36

£89,512

Richard Strange

 

Smith Kline Beecham

Genetic studies in Psoriasis

01/08/1997

65

67,534

Peter Croft

 

Medical Research Council

Establishing North West and Wessex Regional  Biobank

01/04/2004

9

736,154

Richard Strange & Warren Lenney

 

North Staffordshire Respiratory Research Foundation.

Genetics of Asthma

01/10/2000

36

£60,000

Ari Hirvonen (Helsinki)

 

European Union INTAS

Polymorphic genes in lung cancer.

01/08/2000

36

60,000 ECU

Monica Spiteri

 

PPP Healthcare

Genetic epidemiology of chronic obstructive airway disease.

01/09/2001

24

£274,662

Richard Strange & John Lear (Manchester)

3M Healthcare Ltd.

Genetic factors in multiple BCC

01/01/2001

24

£54,413

Clive Hawkins

 

Department of Health Consortium & Serono Pharmaceuticals Ltd.

Host Genotype, response to Ultraviolet light, general immune factors and clinical outcome in Multiple Sclerosis

01/09/2002

36

£

 

Richard Strange & Sudashan Ramachandran

Good Hope Hospital Research and Development Board

Genetics of Coronary Heart Disease.

01/01/2005

24

£32,853

Anthony Fryer, Paul Hoban & Richard Strange

Association for International Cancer Research

Functional analysis of polymorphism in GSTP1

2004

36

£116,769

Publications

School address:
School of Pharmacy and Bioengineering
Hornbeam Building
Keele University
Staffordshire
ST5 5BG

Research centre address:
School of Pharmacy and Bioengineering
Guy Hilton Research Centre
Thornburrow Drive
Stoke-on-Trent
ST4 7QB
Tel: +44 (0) 1782 674988

Jack Ashley building accessibility

Undergraduate enquiries:
Email: enquiries@keele.ac.uk
Tel: +44 (0)1782 734010

Postgraduate enquiries:
Please contact the CPD4ALL team:
Email: phab.postgraduate@keele.ac.uk

 

Keele Centre for Medicines Optimisation (KCMO)
Tel: +44 (0)1782 733831 / 734131

The Virtual Patient project enquiries:
Contact our Digital Development team:
Email: pharmacy.digital@keele.ac.uk