Prof Clive Hawkins

Title: Professor of Clinical Neurology
Phone: +44 (0)1782 679458 (PA)
Email: c.p.hawkins@keele.ac.uk
Location: Institute for Science & Technology in Medicine, Keele University
Guy Hilton Research Centre, Thornburrow Drive, Hartshill Stoke-on-Trent, ST4 7QB United Kingdom
Role: ISTM Research themes: 1. Neuroscience
2. Diagnostic Engineering & Proteomics
3. Health Services Research
Contacting me: By e-mail please.
Prof Clive Hawklins

Professor Hawkins is Professor of Clinical Neurology at Keele University, and Consultant Neurologist to the Regional Neuroscience Centre, Royal Stoke University Hospital, part of the University Hospitals of North Midlands.

He trained as Research fellow, registrar and Lecturer in Clinical Neurology at the Institute of Neurology, National Hospital and University College Hospitals, London. Subsequently he was appointed Senior Lecturer in 1992 and Reader in 2000, to the School of Postgraduate Medicine at Keele.

 

ISTM Research themes: 1. Neuroscience
                                        2. Diagnostic Engineering & Proteomics
                                        3. Health Services Research

Research Interests:

1. Molecular genetics in MS, with regard to susceptibility and outcome/disability. A database has been established of over 1,400 MS patients in the North-West of England (Stoke, Liverpool, Manchester) with blood samples for DNA and disability measurements. Over 80 genetic polymorphisms have been analysed (with Prof Richard Strange, Keele and Prof Bill Ollier / Prof Jane Worthington, Manchester). Current work is focusing on haplotype interactions of candidate genes involved in the process of inflammation and axonal loss. We are currently collaborating with the Broad Institute, Harvard/MIT, Boston, USA and Cambridge, UK.

2. Vision studies to compare functional deficit by psychophysics with pathophysiology (evoked potential) and Magnetic Resonance Imaging of the optic nerve and visual pathway in the brain (with Prof David Foster, University of Manchester). Current work includes studying two types of bilateral optic neuritis using psychophysics.

3. The Keele Multiple Sclerosis Clinical trial unit is currently involved in ten major multi-centre International research trials in Relapsing and Progressive MS. There are 3 post-graduate research students, Lecturer/research registrars studying for a PhD/MD thesis in molecular genetics or vision studies.

 ISTM_hawkins_fig1_339x261  ISTM_hawkins_fig2_378x261

  

Selected Publications

  • Sawcer S, Hellenthal G, Pirinen M, Spencer CCA, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D'alfonso S, Blackburn H, Boneschi FM, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini SE, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BAC, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PIW, Debouverie M, D'hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SFA, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung H-P, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Leppa V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero I-L, Mihalova T, Montalban X, Mottershead J, Myhr K-M, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux J, Rodegher M, Roesner S, Rubio JP, Rueckert I-M, Salvetti M, Salvi E, Santaniello A, Schaefer CA, Schreiber S, Schulze C, Scott RJ, Sellebjerg F, Selmaj KW, Sexton D, Shen L, Simms-Acuna B, Skidmore S, Sleiman PMA, Smestad C, Sorensen PS, Sondergaard HB, Stankovich J, Strange RC, Sulonen A-M, Sundqvist E, Syvaenen A-C, Taddeo F, Taylor B, Blackwell JM, Tienari P, Bramon E, Tourbah A, Brown MA, Tronczynska E, Casas JP, Tubridy N, Corvin A, Vickery J, Jankowski J, Villoslada P, Markus HS, Wang K, Mathew CG, Wason J, Palmer CNA, Wichmann H-E, Plomin R, Willoughby E, Rautanen A, Winkelmann J, Wittig M, Trembath RC, Yaouanq J, Viswanathan AC, Zhang H, Wood NW, Zuvich R, Deloukas P, Langford C, Duncanson A, Oksenberg JR, Pericak-Vance MA, Haines JL, Olsson T, Hillert J, Ivinson AJ, De Jager PL, Peltonen L, Stewart GJ, Hafler DA, Hauser SL, McVean G, Donnelly P, Compston A, Co IMSG, Consor WTCC. 2011. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. NATURE, vol. 476(7359), 214-219. link> doi>
  • Strange RC, Ramachandran S, Zeegers MP, Emes RD, Abraham R, Raveendran V, Boggild M, Gilford J, Hawkins CP. 2010. The Multiple Sclerosis Severity Score: associations with MC1R single nucleotide polymorphisms and host response to ultraviolet radiation. Mult Scler, vol. 16(9), 1109-1116. link> doi>
  • Mamutse G, Woolmore J, Pye E, Partridge J, Boggild M, Young C, Fryer A, Hoban PR, Rukin N, Alldersea J, Strange RC, Hawkins CP. 2008. Vitamin D receptor gene polymorphism is associated with reduced disability in multiple sclerosis. Mult Scler, vol. 14(9), 1280-1283. link> doi>
  • De Stefano N, Filippi M, Hawkins C. 2008. Short-term combination of glatiramer acetate with IV steroid treatment preceding treatment with GA alone assessed by MRI-disease activity in patients with relapsing-remitting multiple sclerosis. JOURNAL OF THE NEUROLOGICAL SCIENCES, vol. 266(1-2), 44-50. link> doi>
  • Kalra S, Durant L, Strange RC, Douglas MR, Hawkins CP, Curnow SJ. 2015. Role of Th17 and CCR6 cell lineage in multiple sclerosis. MULTIPLE SCLEROSIS JOURNAL (vol. 21, pp. 796-797). link>

Full Publications List show

Books

  • HAWKINS CP and Wolinsky J. 2000. Principles of Treatments in Multiple Sclerosis. Butterworth-Heinemann.

Journal Articles

  • Jones K, Linhart C, Hawkins C, Exley C. 2017. Urinary Excretion of Aluminium and Silicon in Secondary Progressive Multiple Sclerosis. EBioMedicine, vol. 26, 60-67. link> doi> full text>
  • Griffin SM, Pickard MR, Orme RP, Hawkins CP, Williams AC, Fricker RA. 2017. Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations. PLoS One, vol. 12(8), e0183358. link> doi> full text>
  • Griffin SM, Pickard MR, Orme RP, Hawkins CP, Fricker RA. 2013. Nicotinamide promotes neuronal differentiation of mouse embryonic stem cells in vitro. Neuroreport, vol. 24(18), 1041-1046. link> doi> full text>
  • Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, Martin C, Zipp F, D'Alfonso S, Martinelli-Boneschi F, Taylor B, Harbo HF, Kockum I, Hillert J, Olsson T, Ban M, Oksenberg JR, Hintzen R, Barcellos LF, Agliardi C, Alfredsson L, Alizadeh M, Anderson C, Andrews R, Sondergaard HB, Baker A, Band G, Baranzini SE, Barizzone N, Barrett J, Bellenguez C, Bergamaschi L, Bernardinelli L, Berthele A, Biberacher V, Binder TMC, Blackburn H, Bomfim IL, Brambilla P, Broadley S, Brochet B, Brundin L, Buck D, Butzkueven H, Caillier SJ, Camu W, Carpentier W, Cavalla P, Celius EG, Coman I, Comi G, Corrado L, Cosemans L, Cournu-Rebeix I, Cree BAC, Cusi D, Damotte V, Defer G, Delgado SR, Deloukas P, di Sapio A, Dilthey AT, Donnelly P, Dubois B, Duddy M, Edkins S, Elovaara I, Esposito F, Evangelou N, Fiddes B, Field J, Franke A, Freeman C, Frohlich IY, Galimberti D, Gieger C, Gourraud P-A, Graetz C, Graham A, Grummel V, Guaschino C, Hadjixenofontos A, Hakonarson H, Halfpenny C, Hall G, Hall P, Hamsten A, Harley J, Harrower T, Hawkins C, Hellenthal G, Hillier C, Hobart J, Hoshi M, Hunt SE, Jagodic M, Jelcic I, Jochim A, Kendall B, Kermode A, Kilpatrick T, Koivisto K, Konidari I, Korn T, Kronsbein H, Langford C, Larsson M, Lathrop M, Lebrun-Frenay C, Lechner-Scott J, Lee MH, Leone MA, Leppa V, Liberatore G, Lie BA, Lill CM, Linden M, Link J, Luessi F, Lycke J, Macciardi F, Mannisto S, Manrique CP, Martin R, Martinelli V, Mason D, Mazibrada G, McCabe C, Mero I-L, Mescheriakova J, Moutsianas L, Myhr K-M, Nagels G, Nicholas R, Nilsson P, Piehl F, Pirinen M, Price SE, Quach H, Reunanen M, Robberecht W, Robertson NP, Rodegher M, Rog D, Salvetti M, Schnetz-Boutaud NC, Sellebjerg F, Selter RC, Schaefer C, Shaunak S, Shen L, Shields S, Siffrin V, Slee M, Sorensen PS, Sorosina M, Sospedra M, Spurkland A, Strange A, Sundqvist E, Thijs V, Thorpe J, Ticca A, Tienari P, van Duijn C, Visser EM, Vucic S, Westerlind H, Wiley JS, Wilkins A, Wilson JF, Winkelmann J, Zajicek J, Zindler E, Haines JL, Pericak-Vance MA, Ivinson AJ, Stewart G, Hafler D, Hauser SL, Compston A, McVean G, De Jager P, Sawcer SJ, McCauley JL, Consor WTCC, IIBDGC IIBDGC. 2013. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. NATURE GENETICS, vol. 45(11), 1353-+. link> doi>
  • Young CA, Mills RJ, Woolmore J, Hawkins CP, Tennant A. 2012. The unidimensional self-efficacy scale for MS (USE-MS): developing a patient based and patient reported outcome. MULTIPLE SCLEROSIS JOURNAL, vol. 18(9), 1326-1333. link> doi>
  • Nayak D, Kalra S, Nayak S, Abraham R, Gilford J, Pherwani A, Jones LD, Ramachandran S, Strange RC, Hawkins CP. 2011. Optico-spinal variant of multiple sclerosis (OSMS) in British patients. Clinical and neuroimaging studies with therapeutic challenges. MULTIPLE SCLEROSIS JOURNAL, vol. 17, S523-S524. link>
  • Sawcer S, Hellenthal G, Pirinen M, Spencer CCA, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D'alfonso S, Blackburn H, Boneschi FM, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini SE, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BAC, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PIW, Debouverie M, D'hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SFA, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung H-P, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Leppa V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero I-L, Mihalova T, Montalban X, Mottershead J, Myhr K-M, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux J, Rodegher M, Roesner S, Rubio JP, Rueckert I-M, Salvetti M, Salvi E, Santaniello A, Schaefer CA, Schreiber S, Schulze C, Scott RJ, Sellebjerg F, Selmaj KW, Sexton D, Shen L, Simms-Acuna B, Skidmore S, Sleiman PMA, Smestad C, Sorensen PS, Sondergaard HB, Stankovich J, Strange RC, Sulonen A-M, Sundqvist E, Syvaenen A-C, Taddeo F, Taylor B, Blackwell JM, Tienari P, Bramon E, Tourbah A, Brown MA, Tronczynska E, Casas JP, Tubridy N, Corvin A, Vickery J, Jankowski J, Villoslada P, Markus HS, Wang K, Mathew CG, Wason J, Palmer CNA, Wichmann H-E, Plomin R, Willoughby E, Rautanen A, Winkelmann J, Wittig M, Trembath RC, Yaouanq J, Viswanathan AC, Zhang H, Wood NW, Zuvich R, Deloukas P, Langford C, Duncanson A, Oksenberg JR, Pericak-Vance MA, Haines JL, Olsson T, Hillert J, Ivinson AJ, De Jager PL, Peltonen L, Stewart GJ, Hafler DA, Hauser SL, McVean G, Donnelly P, Compston A, Co IMSG, Consor WTCC. 2011. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. NATURE, vol. 476(7359), 214-219. link> doi>
  • Strange RC, Ramachandran S, Zeegers MP, Emes RD, Abraham R, Raveendran V, Boggild M, Gilford J, Hawkins CP. 2010. The Multiple Sclerosis Severity Score: associations with MC1R single nucleotide polymorphisms and host response to ultraviolet radiation. Mult Scler, vol. 16(9), 1109-1116. link> doi>
  • Esposito F, Patsopoulos NA, Cepok S, Kockum I, Leppa V, Booth DR, Heard RN, Stewart GJ, Cox M, Scott RJ, Lechner-Scott J, Goris A, Dobosi R, Dubois B, Rioux JD, Oturai AB, Sondergaard HB, Sellebjerg F, Sorensen PS, Reunanen M, Koivisto K, Cournu-Rebeix I, Fontaine B, Winkelmann J, Gieger C, Infante-Duarte C, Zipp F, Bergamaschi L, Leone M, Bergamaschi R, Cavalla P, Lorentzen AR, Mero I-L, Celius EG, Harbo HF, Spurkland A, Comabella M, Brynedal B, Alfredsson L, Bernardinelli L, Robertson NP, Hawkins CP, Barcellos LF, Beecham G, Bush W, Cree BAC, Daly MJ, Ivinson AJ, Aubin C, Compston A, D'Alfonso S, Haines JL, Hauser SL, Hemmer B, Hillert J, McCauley JL, Oksenberg J, Olsson T, Palotie A, Peltonen L, Pericak-Vance MA, Saarela J, Sawcer SJ, Stranger B, Boneschi FM, Comi G, Hafler DA, de Bakker PIW, De Jager PL, IMSGC. 2010. IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci. GENES AND IMMUNITY, vol. 11(5), 397-405. link> doi>
  • Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S, Compston A, WTCCC. 2009. Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. EUROPEAN JOURNAL OF HUMAN GENETICS, vol. 17(10), 1309-1313. link> doi>
  • Booth DR, Heard RN, Stewart GJ, Goris A, Dobosi R, Dubois B, Lorentzen AR, Celius EG, Harbo HF, Spurkland A, Olsson T, Kockum I, Link J, Hillert J, Ban M, Baker A, Sawcer S, Compston A, Mihalova T, Strange R, Hawkins C, Ingram G, Robertson NP, De Jager PL, Hafler DA, Barcellos LF, Ivinson AJ, Pericak-Vance M, Oksenberg JR, Hauser SL, McCauley JL, Sexton D, Haines J, IMSGC. 2009. The expanding genetic overlap between multiple sclerosis and type I diabetes. GENES AND IMMUNITY, vol. 10(1), 11-14. link> doi>
  • Mamutse G, Woolmore J, Pye E, Partridge J, Boggild M, Young C, Fryer A, Hoban PR, Rukin N, Alldersea J, Strange RC, Hawkins CP. 2008. Vitamin D receptor gene polymorphism is associated with reduced disability in multiple sclerosis. Mult Scler, vol. 14(9), 1280-1283. link> doi>
  • De Stefano N, Filippi M, Hawkins C. 2008. Short-term combination of glatiramer acetate with IV steroid treatment preceding treatment with GA alone assessed by MRI-disease activity in patients with relapsing-remitting multiple sclerosis. JOURNAL OF THE NEUROLOGICAL SCIENCES, vol. 266(1-2), 44-50. link> doi>
  • Woolmore J, Stone M, Holley S, Jenkinson P, Ike A, Jones P, Fryer A, Strange R, Stephens R, Langdon D, Hawkins C. 2008. Polymorphisms of the cannabinoid 1 receptor gene and cognitive impairment in multiple sclerosis. Mult Scler, vol. 14(2), 177-182. link> doi>
  • Woolmore JA, Stone M, Pye EM, Partridge JM, Boggild M, Young C, Jones PW, Fryer AA, Hawkins CP, Strange RC. 2007. Studies of associations between disability in multiple sclerosis, skin type, gender and ultraviolet radiation. Mult Scler, vol. 13(3), 369-375. link> doi>
  • Stone M and Hawkins C. 2007. Encephalitis: an overview. Neurophychological Rehabilitation, vol. 17(4-5), 429-449.
  • Exley C, Mamutse G, Korchazhkina O, Pye E, Strekopytov S, Polwart A, Hawkins C. 2006. Elevated urinary excretion of aluminium and iron in multiple sclerosis. Mult Scler, vol. 12(5), 533-540. link> doi>
  • members of steering/advisory committee and Hawkins CP. 2006. A randomised, placebo-controlled trial of Natalizumab for relapsing multiple sclerosis. New England Journal of Medicine, vol. 354, 899-910.
  • members of steering/advisory committee and Hawkins CP. 2006. Evaluation of patients treated with Natalizumab for progressive multifocal leukoencephalopathy. New England Journal of Medicine, vol. 354, 924-933.
  • Hinks A, Barton A, John S, Hawkins C, Griffiths CE, Donn R, Thomson W, Silman A, Worthington J. 2005. Association between the PTPN22 gene, rheumatoid arthritis and autoimmune disease in the UK population. Arthritis Rheumatism, vol. 52, 1694-1699.
  • Alam M, Pravica V, Fryer AA, Hutchinson IV, Hawkins CP. 2005. Novel polymorphisms in the promoter region of the human nerve growth factor gene. International Journal of Immunogenetics, vol. 32, 379-382. doi>
  • BARTON A, WOOLMORE JA, WARD D, EYRE S, HINKS A, OLLIER WE, STRANGE RC, FRYER AA, JOHN S, HAWKINS CP, WORTHINGTON J. 2004. Association of protein kinase C alpha (PRKCA) gene with multiple sclerosis in a UK population. Brain, vol. 127(8), 1717-1722. doi>
  • Partridge JM, Weatherby SJM, Woolmore JA, Highland DJ, Fryer AA, Mann CLA, Boggild MD, Ollier WER, Strange RC, Hawkins CP. 2004. Susceptibility and outcome in MS: associations with polymorphisms in pigmentation-related genes. Neurology, vol. 62(12), 2323-2325. link> doi>
  • Weatherby MJC, Weatherby SJM, Hawkins CP. 2003. Does trauma trigger multiple sclerosis? 2: A medicolegal view. HOSPITAL MEDICINE, vol. 64(11), 651-653. link> doi>
  • Weatherby SJM and Hawkins CP. 2003. Does trauma trigger multiple sclerosis? 1: A controversy. HOSPITAL MEDICINE, vol. 64(10), 581-584. link> doi>
  • members of steering/advisory committees and Hawkins CP. 2003. A controlled trial of Natalizumab for relapsing multiple sclerosis. New England Journal of Medicine, vol. 348, 15-23.
  • Nicholas RS, Partridge J, Donn RP, Hawkins CP, Boggild MD. 2003. The role of the PTPRC (CD45) mutation in the development of Multiple Sclerosis in the North West region of the United Kingdom. Journal of Neurology, Neurosurgery and Psychiatry, vol. 74, 944-945.
  • Pye EM, Weatherby SJ, Kesson O, Foster DH, Hawkins CP, Keele MS. 2002. A comparison of bilateral simultaneous and bilateral sequential optic neuritis using visual psychophysics. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, vol. 73(2), 235. link>
  • Mann CLA, Davies MB, Stevenson VL, Leary SM, Boggild MD, Ko Ko C, Jones PW, Fryer AA, Strange RC, Thompson AJ, Hawkins CP. 2002. Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity. J Neuroimmunol, vol. 129(1-2), 197-204. link> doi>
  • Partridge J, Fryer AA, Strange RC, Boggild MD, Hawkins CP. 2002. Chemokine receptor 5 delta 32 polymorphism: susceptibility to and outcome from multiple sclerosis. Journal of Neurology, vol. 249, 173-174.
  • Weatherby SJM, Fryer AA, Mann C, Ollier W, Strange R, Hawkins CP. 2001. Epistasis: a potentially important concept in multiple sclerosis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, vol. 70(2), 283. link>
  • members of steering/advisory committees and Hawkins CP. 2001. European/Canadian multi-centre, double-blind, randomised, placebo-controlled study of the effects of glatiramer acetate on the magnetic resonance imaging-measured disease activity and burden in patients with relapsing multiple sclerosis. Annals of Neurology, vol. 49, 290-297.
  • Hawkins CP. 2001. Glatiramer acetate (copolymer 1) in relapsing multiple sclerosis. Drug and Therapeutic Bulletin, vol. 39(6), 41-43.
  • Weatherby SJ, Thomson W, Pepper L, Donn R, Worthington J, Mann CL, Davies MB, Fryer AA, Boggild MD, Young CA, Jones PW, Strange RC, Ollier WE, Hawkins CP. 2001. HLA-DRB1 and disease outcome in multiple sclerosis. J Neurol, vol. 248(4), 304-310. link> doi>
  • Weatherby SJM and Hawkins CP. 2001. Multiple Sclerosis: new pathophysiological and therapeutic concepts. Journal of Royal College of Physicians, vol. 31, 134-148.
  • members of steering/advisory committee and Hawkins CP. 2001. Randomised controlled trial of interferon-beta 1a in secondary progressive multiple sclerosis: clinical results. Neurology, vol. 56, 1496-1504.
  • members of steering/advisory committee and Hawkins CP. 2001. Randomised controlled trial of interferon-beta 1a in secondary progressive Multiple Sclerosis: MRI results. Neurology, vol. 56, 1505-1513.
  • Caruana PA, Davies MB, Weatherby SJ, Williams R, Haq N, Foster DH, Hawkins CP. 2000. Correlation of MRI lesions with visual psychophysical deficit in secondary progressive multiple sclerosis. Brain, vol. 123 ( Pt 7), 1471-1480. link> doi>
  • Weatherby SJM, Mann CLA, Davies MB, Fryer AA, Haq N, Strange RC, Hawkins CP. 2000. A pilot study of the relationship between gadolinium-enhancing lesions, gender effect and polymorphisms of antioxidant enzymes in multiple sclerosis. JOURNAL OF NEUROLOGY, vol. 247(6), 467-470. link> doi>
  • Weatherby SJM, Mann CLA, Fryer AA, Strange RC, Hawkins CP, Stevenson VL, Leary SM, Thompson AJ. 2000. No association between the APOE epsilon 4 allele and outcome and susceptibility in primary progressive multiple sclerosis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, vol. 68(4), 532. link> doi>
  • Mann CLA, Davies MB, Boggild MD, Alldersea J, Fryer AA, Jones PW, Ko CK, Young C, Strange RC, Hawkins CP. 2000. Glutathione S-transferase polymorphisms in MS - Their relationship to disability. NEUROLOGY, vol. 54(3), 552-557. link> doi>
  • Weatherby SJ, Mann CL, Davies MB, Carthy D, Fryer AA, Boggild MD, Young C, Strange RC, Ollier W, Hawkins CP. 2000. Polymorphisms of apolipoprotein E; outcome and susceptibility in multiple sclerosis. Mult Scler, vol. 6(1), 32-36. link> doi>
  • members of steering and advisory committees and Hawkins CP. 2000. Linomide in the treatment of Multiple Sclerosis: MRI results from phase-III trials. Multiple Sclerosis, vol. 6, 99-104.
  • Davies MB, Williams R, Haq N, Pelosi L, Hawkins CP. 1998. MRI of optic nerve and postchiasmal visual pathways and visual evoked potentials in secondary progressive multiple sclerosis. Neuroradiology, vol. 40(12), 765-770. link> doi>
  • Fielding RE, Hawkins CP, Hand MF, Heath PD, Davies SJ. 1998. Seizures complicating adult Henoch-Schönlein purpura. Nephrol Dial Transplant, vol. 13(3), 761-762. link> doi>
  • Salih AM, Nixon NB, Gagan RM, Heath P, Hawkins CP, Dawes PT, Mattey DL. 1996. Anti-ganglioside antibodies in patients with rheumatoid arthritis complicated by peripheral neuropathy. Br J Rheumatol, vol. 35(8), 725-731. link> doi> full text>
  • Boggild MD, Williams R, Haq N, Hawkins CP. 1996. Cortical plaques visualised by fluid-attenuated inversion recovery imaging in relapsing multiple sclerosis. Neuroradiology, vol. 38 Suppl 1, S10-S13. link> doi>
  • HAWKINS CP and HERON JR. 1988. SUBARACHNOID HEMORRHAGE FROM SPINAL TUMOR (IN THE ABSENCE OF SPINAL SYMPTOMS OR SIGNS). JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, vol. 51(2), 305-307. link> doi>
  • Ramachandran S, Strange RC, Jones PW, Kalra S, Nayak D, Hawkins CP. 2014. Associations between onset age and disability in multiple sclerosis patients studied using MSSS and a progression model. Mult Scler Relat Disord, vol. 3(5), 593-599. link> doi>
  • Ramachandran S, Strange RC, Kalra S, Nayak D, Zeegers MP, Gilford J, Hawkins CP. 2013. Progression of disability in multiple sclerosis: A study of factors influencing median time to reach an EDSS value. Mult Scler Relat Disord, vol. 2(2), 109-116. link> doi>

Chapters

  • HAWKINS CP and Wolinsky J. 2000. Overview of Treatment Strategies for Relapsing and Progressive Multiple Sclerosis. In Principles of Treatments in Multiple Sclerosis. FRCP CPHD and MD JSW (Eds.). Butterworth-Heinemann.
  • HAWKINS CP. 2000. Pathogenesis and Clinical Subtypes of Multiple Sclerosis. In Principles of Treatments in Multiple Sclerosis. FRCP CPHD and MD JSW (Eds.). Butterworth-Heinemann.
  • HAWKINS CP. 1998. Magnetic Resonance Imaging of Blood-Brain Barrier permeability. In Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology. MD WMP (Ed.). Cambridge University Press.
  • HAWKINS CP. 1998. Spinal Features of Multiple Sclerosis. In Spinal Cord Diseases: Diagnosis and Treatment. Engler G (Ed.). Informa HealthCare.
  • HAWKINS CP and Thompson AJ. 1992. Recent Advances in Neurology. In Anasthesia Review. Kaufman L (Ed.). Churchill-Livingstone.

Other

  • Kalra S, Curnow JS, Hawkins CP. 2017. CCR6+Th1 and Th17 Cells in Multiple Sclerosis. MULTIPLE SCLEROSIS JOURNAL (vol. 23, p. 103). link>
  • Plantone D, Solanky B, Miller D, Pavitt S, Giovannoni G, Wheeler-Kingshott CG, De Angelis F, Doshi A, Weir C, Parker R, Stallard N, Hawkins C, Sharrack B, Cranswick G, Chandran S, Chataway J, Trialists MS-SMART. 2016. Initial cross-sectional MR spectroscopy analysis of a cohort of secondary progressive MS patients enrolled in the MS-SMART trial. MULTIPLE SCLEROSIS JOURNAL (vol. 22, pp. 512-513). link>
  • Connick P, Miller D, Pavitt S, Giovannoni G, Wheeler-Kingshott C, Weir C, Stallard N, Hawkins C, Sharrack B, Cranswick G, Chandran S, Chataway J, Trialists MS-SMART. 2016. MS-SMART trial design and recruitment status: a multi-arm phase IIB randomised double blind placebo-controlled clinical trial comparing the efficacy of three repositioned neuroprotective drugs in secondary progressive multiple sclerosis. MULTIPLE SCLEROSIS JOURNAL (vol. 22, pp. 630-631). link>
  • De Angelis F, Cameron J, Connick P, Miller D, Pavitt S, Giovannoni G, Wheeler-Kingshott CG, Plantone D, Doshi A, Weir C, Parker R, Stallard N, Hawkins C, Sharrack B, Cranswick G, Chandran S, Chataway J, Trialists MS-SMART. 2016. Optical coherence tomography in secondary progressive multiple sclerosis: a baseline data report from the MS-SMART trial. MULTIPLE SCLEROSIS JOURNAL (vol. 22, pp. 250-251). link>
  • Griffin S, Pickard M, Orme R, Hawkins C, Williams A, Chari D, Fricker R. 2014. THE INFLUENCE OF NICOTINAMIDE ON THE DEVELOPMENT OF NEURONS. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 85). link> doi>
  • Mihalova T, Ban M, Baker A, Abraham R, Strange R, Hawkins CP. 2010. IL2RA AND CD226 GENOTYPES INFLUENCE MULTIPLE SCLEROSIS DISEASE OUTCOME. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 81, p. E27). link> doi>
  • Goris A, Dobosi R, Booth D, Stewart G, Cournu-Rebeix I, Fontaine B, Winkelmann J, Cepok S, Hemmer B, Bergamaschi L, Leone M, D'Alfonso S, Lorentzen AR, Harbo H, Ban M, Sawcer SJ, Compston A, Mihalova T, Hawkins C, Ingram G, Robertson N, De Jager P, Hafler D, Barcellos L, Ivinson A, McCauley J, Pericak-Vance M, Oksenberg J, Hauser S, Sexton D, Haines J, Dubois B. 2009. Investigation of novel type 1 diabetes loci in multiple sclerosis. MULTIPLE SCLEROSIS (vol. 15, p. S185). link>
  • Pye EM, Amano K, Kesson D, Hawkins CP, Foster DH. 2008. Colour constancy after optic neuritis associated with multiple sclerosis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 79, p. 340). link>
  • Stone MJ, Woolmore J, Jenkinson P, Mihalova T, Stevenson R, Strange R, Langdon D, Hawkins CP. 2007. Cathepsin D polymorphisms and cognitive impairment in multiple sclerosis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 78, p. 1037). link>
  • Stone MJ, Woolmore JA, Jenkinson P, Stephens R, Mihalova T, Langdon D, Fryer AA, Strange R, Hawkins CP. 2007. Cognitive impairment and polymorphisms of cathepsin D in multiple sclerosis. JOURNAL OF NEUROLOGY (vol. 254, p. 163). link>
  • Mamutse G, Exley C, Korchazhkina O, Pye E, Strekopytov S, Polwart A, Hawkins CP. 2006. Elevated urinary excretion of aluminium and iron in multiple sclerosis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 77, p. 1398). link>
  • Mihalova T, Eyre S, Barton A, Bowes J, Rukin N, Stone M, Boggild M, Young CA, Fryer A, Hoban P, Worthington J, Strange R, Hawkins CP. 2006. Genetic polymorphism in type III promoter of the major histocompatibility complex class II transactivator gene is associated with susceptibility to multiple sclerosis. MULTIPLE SCLEROSIS (vol. 12, pp. S73-S74). link>
  • Exley C, Mamutse G, Korchazhkina O, Pye E, Srekopytov S, Polwart A, Hawkins CP. 2006. Elevated urinary excretion of aluminium and iron in multiple sclerosis. JOURNAL OF NEUROLOGY (vol. 253, p. 80). link>
  • Woolmore JA, Jenkinson PM, Stephens R, Weatherby SJ, Payton A, Fryer AA, Strange RS, Ollier WER, Jones PW, Langdon D, Hawkins CP. 2005. Neuropsychological outcome and apolipoprotein E epsilon 4 polymorphism in multiple sclerosis. JOURNAL OF NEUROLOGY (vol. 252, p. 131). link>
  • Woolmore JA, Ike A, Jenkinson RM, Stephens R, Holley S, Fryer AA, Strange RS, Jones RW, Langdon D, Hawkins CP. 2005. Neuropsychological outcome and cannabinoid receptor 1 polymorphism in multiple sclerosis. JOURNAL OF NEUROLOGY (vol. 252, p. 66). link>
  • Woolmore JA, Pye E, Partridge JM, Boggild M, Young C, Jones PW, Fryer AA, Hawkins CP, Strange RS. 2005. Ultraviolet radiation and outcome in multiple sclerosis. JOURNAL OF NEUROLOGY (vol. 252, p. 74). link>
  • Hinks A, Barton A, Simpson A, John S, Eyre S, Bruce I, Hawkins C, Griffiths CEM, Donn R, Thomson W, Silman A, Worthington J, Grp BSPARS. 2005. A role for the protein tyrosine phosphatase N22 (PTPN22) gene in autoimmune disease. RHEUMATOLOGY (vol. 44, p. I5). link>
  • Woolmore JA, Jenkinson PM, Stephens R, Weatherby SJ, Fryer AA, Strange RC, Payton A, Ollier W, Jones P, Langdon D, Hawkins CP, Keele MS. 2005. Neuropsychological outcome and APOE polymorphism in multiple sclerosis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 76, p. 158). link>
  • Pye E, Weatherby S, Davies M, Caruana P, Williams R, Haq N, Foster D, Hawkins C. 2004. Visual psychophysical deficit, visual evoked potentials and magnetic resonance imaging in the treatment of secondary progressive multiple sclerosis. JOURNAL OF NEUROLOGY (vol. 251, p. 151). link>
  • Woolmore JA, Barton A, John S, Worthington J, Fryer AA, Strange RC, Hawkins CP. 2004. High density single nucleotide polymorphism mapping of protein kinase C alpha gene in a UK population of multiple sclerosis patients. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 75, p. 517). link>
  • Pye EM, Weatherby SJM, Kesson D, Foster DH, Hawkins CP. 2003. The effect of corticosteroid on conduction in the visual pathways: A serial study using visual psychophysics. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (vol. 74, p. 408). link>
  • Kalra S, Durant L, Strange RC, Douglas MR, Hawkins CP, Curnow SJ. 2015. Role of Th17 and CCR6 cell lineage in multiple sclerosis. MULTIPLE SCLEROSIS JOURNAL (vol. 21, pp. 796-797). link>

In August 2010 Prof Hawkins became a Co-Director of the West Midlands (North) Comprehensive Local Research Network.