Dr Seynabou Sougoufara

Seynabou Sougoufara 200x200

Dr Seynabou Sougoufara

Frederic Tripet 200x200

Professor Fredric Tripet

The impact of insecticide resistance on the fitness of Anopheles coluzzil mosquitoes

Dr Seynabou Sougoufara joins us from Vecteurs-InfectionsTropicales et Mediteranneenes (VITRO), Dakar, Senegal to undertake her fellowship at Keele from April-June 2019. During her time here she will be hosted by her academic partner Professor Fredric Tripet from the Centre for Applied Entomology and Parasitology (CAEP) in the School of Life Sciences and the Institute of Liberal Arts and Sciences.

Dr Sougoufara‘s doctorate from the University Cheikh Anta Diop Dakar in 2015 involved work on key features of the Anopheles mosquitoes (vectors) that transmit malaria between people in a Senegalese village setting. In her time at Keele she will be working with Professor Tripet and colleagues in CAEP on their joint project; The impact of insecticide resistance on the fitness of Anopheles coluzzil mosquitoes, which will focus on assessing the insecticide resistance and the mating behaviour of a new strain of Anopheles coluzzii mosquitoes. Further, it will draw on the facilities and expertise at Keele to investigate the biology and ecology of different resistant phenotypes of mosquitoes, for example, the role of the mosquito’s cuticle in reducing the penetration of the insecticide.

Malaria is a major public health problem in sub-Sahara African countries (WHO, 2017). Control measures against this disease are mainly based on anti-vectorial programmes that use insecticide-treated bed nets and indoor residual spraying. However, resistance to the main chemical classes of insecticides used in public health is growing. For this reason, studies evaluating the fitness of resistance in mosquito populations are very important in informing the design and implementation of effective pesticide-resistance management schemes.

The research project brings together Professor Tripet’s extensive experience in molecular ecology, population genetics and behaviour and Seynabou’s experiences in research field conditions studying the composition and the diversity and dynamics of malaria vectors. The work aims to address current knowledge gaps in important aspects of the mosquito bio-ecology challenge in the management of insecticide resistance. This focus on the ways that malaria vectors adapt to human-modified environments will lead to better understandings of malaria vector resistance and behavioural changes in malaria vectors.

If you would like to know more about the plans for Dr Seynabou’s fellowship and would like to meet her during her visit to Keele, please contact Jo Fylnn.