Abstract: Epilepsy is defined as the tendency to have recurrent seizures. However, clinical trials in this area often model time to a specific event such as treatment failure, or 12-month remission from seizures, rather than considering all post-randomisation seizures. Several models for seizure recurrence will be compared using all recorded seizures within the Standard Versus New Antiepileptic Drug study. As well as demonstrating graphical methods to aid comparisons across models, this talk will discuss how patient & clinician involvement can shape a research proposal both in design and focus, but also in terms of presentation and implementation of the results.

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