Stereoselective Synthesis of Tetrahydrofuran Natural Products

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Posted on 03 April 2017

Dr Alistair Boyer, of Glasgow University, recently gave a talk at Keele on his research into the stereoselective synthesis of tetrahydrofuran natural products (29th of March). In the audience was Emeritus Professor of Chemistry, David Morgan, who carried out the early isolation studies on the complex natural product Azadirachtin at Keele in the 1960s and 70s. During his PhD studies at Cambridge University, Alistair was part of the team, led by Steven V. Ley, that completed the total synthesis of Azadirachtin. Something that had eluded the efforts of many research groups, this landmark achievement in the history of organic synthesis actually took 25 years to complete. Pictured here are David (left) and Alistair (right) with the structure of Azadirachtin on the whiteboard. Alistair has just been elected to a prestigious Royal Society University-Research-Fellowship sponsored by TATA group companies.