PHA-20018 - Applied Pharmaceutical Science II
Coordinator: Jihong Han Room: HORBM1.38 Tel: +44 1782 7 33834
Lecture Time: See Timetable...
Level: Level 5
Credits: 30
Study Hours: 300
School Office:

Programme/Approved Electives for 2025/26

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

None.

Barred Combinations

None.

Description for 2025/26

This module provides a detailed and fully contextualised analysis of pharmaceutics and drug delivery, alongside the relevant manufacturing and safety elements of pharmaceutical production.

After a general introduction to pharmaceutics, you will study the properties and applications of solutions, followed by rheology and the flow properties of liquids and semisolids. Interfacial phenomenon and disperse systems, including surface tension, surface active agents, emulsions, and suspensions will be covered in detail since these concepts are of vital importance in the performance of many dosage forms. Solid dosage forms will be discussed in Semester 2. All of the topics covered will be supported by a comprehensive programme of practical exercises.

Woven throughout the module is development of essential team-working and leadership skills: group-based tasks within the laboratory classes and practical skills workshops provide you with a forum to demonstrate your potential to work in and lead pharmaceutical science formulation teams.

Aims
This module aims to provide a fully contextualised analysis of crucial topics covering the breadth of pharmaceutics, formulation science, and manufacture and drug delivery in the pharmaceutical sciences.

Talis Aspire Reading List
Any reading lists will be provided by the start of the course.
http://lists.lib.keele.ac.uk/modules/pha-20018/lists

Intended Learning Outcomes

To discuss and implement an integrated approach that connects pharmaceutical science and pharmaceutical manufacturing, in order to enhance patient care
: 1,2,3,4
Explain how a patient¿s physiology and pathophysiology inform the choice of drug in the context of absorption, distribution, metabolism and excretion (ADME) models: 2,4
Demonstrate application of the underpinning concepts in physical chemistry and materials science which underpin the formulation of dosage forms, including parenteral, solid and semi-solid dosage forms, to patient-relevant outcomes: 1
Evaluate and select processes and formulations appropriate to the manufacture and testing of a wide range of patient-relevant dosage forms, including parenteral, solid and semi-solid dosage forms: 1,2,3,4
Apply competence in pharmaceutical calculations related to pharmaceutics towards a range of dosage forms, including parenteral, semi-solid, solid and particulate dose forms, with reference where appropriate to pharmacopoeial standards: 1,2,3,4
Demonstrate the role of skin physiology in percutaneous absorption, including its application to the development of dermal and transdermal delivery systems: 2,4

Study hours

Large- and small-group teaching sessions: 50 hours
Skills-based practical work: 50 hours, including multiple laboratory sessions dealing with a wide range of formulation types.
Directed private study, revision and assessment: 198 hours
Exam: 2 hours


School Rules

None

Description of Module Assessment

1: Laboratory Practicals weighted 25%
Laboratory skills assessment 1
The laboratory assessment will comprise elements from multiple laboratory sessions. Students will be required to produce a laboratory report (Word limit: 1500 words). This assessment involves students working in groups. There are three parts to the assessment: - the batch record sheet (BRS) has to be completed by the group; this is a group assessment and students in the same group are awarded the same mark; this is weighted as 20% of the assessment - a COSHH form has to be completed (10% of the assessment) - the laboratory report is assessed for each individual student; this is weighted as 70% of the assessment.

2: Exam weighted 25%
End of semester 1 examination
The end of semester 1 examination will contain multiple choice questions (MCQ) which cover content delivered in Semester 1. This examination will take 1 hour and 30 minutes in duration.

3: Laboratory Practicals weighted 25%
Laboratory skills assessment 2
The laboratory assessment will comprise elements from multiple laboratory sessions and will focus on the pharmaceutics content of the module. The assessments will be: - the formulation manufacture and testing laboratory sessions This assessment involves students working in groups. There are three parts to the assessment: - The batch record sheet (BRS) has to be completed by the group; this is a group assessment, and students in the same group are awarded the same mark; this is weighted as 20% of the assessment - A COSHH form has to be completed (10% of the assessment) - The laboratory report is assessed for each individual student; this is weighted as 70% of the assessment (Word limit: 1500 words).

4: Exam weighted 25%
End of semester 2 examination
The end of semester 2 examination will contain multiple choice questions (MCQ) which cover content delivered in Semester 2. This examination will take 1 hour and 30 minutes in duration.