PHA-20009 - MPharm Programme Stage 2
Coordinator: Jonathan D Berry Room: HORN 2.16 Tel: +44 1782 7 34793
Lecture Time: See Timetable...
Level: Level 5
Credits: 120
Study Hours: 1200
School Office:

Programme/Approved Electives for 2022/23

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

None

Barred Combinations

None

Description for 2022/23

Stage 2 continues to provide a fully integrated and contextualised course of study comprising periods of learning, assessment, feedback, and reflection. Stage 2 consists of two cycles throughout which run the linked themes of pharmaceutical science and formulation, pharmacology and drug action, therapeutics and law ethics and pharmacy practice. This allows the practice of pharmacy to be linked explicitly to the science-rich aspects of the programme. Specific topics will include the relationship between absorption, distribution and elimination of drugs and their physico-chemical properties and formulation, analytical techniques, the manufacture and use of sterile pharmaceuticals, the action of drugs on molecular targets, cells and physiological systems, therapeutic and adverse effects of drugs, the potential role of pharmacogenetics and pharmacogenomics in personalised medicine, extemporaneous preparation of medicines, drug interactions, drug resistance and the consequences for patient care and the lawful supply of medicinal products. The theme of the gastrointestinal system is currently used to allow students to develop the links between these sub-disciplines throughout the year.

Aims
The principal aim is to further develop knowledge and skills in a wide variety of disciplines by demonstrating the linkages between applied topics in science and practice that underpin all subsequent learning.

Talis Aspire Reading List
Any reading lists will be provided by the start of the course.
http://lists.lib.keele.ac.uk/modules/pha-20009/lists

Intended Learning Outcomes

Demonstrate knowledge of and apply an integrated approach towards patient care which links pharmaceutical science and pharmacy practice: 1,2,3,4,5,6,7,8
Explain how physiological patient factors affect the choice of pharmacological agents to treat disease states based upon absorption, distribution, metabolism and excretion data
: 1,2,3,4,5,6,7,8
Identify and describe the mechanisms of common drug-drug, drug-patient and drug-food interactions and their consequences for patient care: 1,2,3,4,5,6,7,8
Explain how drug resistance and drug interactions have consequences for patient care: 1,2,3,4,5,6,7,8
Explain the relationship between absorption, distribution, metabolism and elimination of drugs and their physicochemical properties and formulation: 1,2,3,4,5,6,7,8
Compare and evaluate the efficiency and safety of different routes of drug administration: 1,2,3,4,5,6,7,8
Explain the underpinning concepts in physical chemistry and materials science which underpin drug formulation: 1,2,3,4,6,7,8
Evaluate and select processes and formulations appropriate to the manufacture of specified drug products: 1,2,3,4,5,6,7,8
Explain the processes involved in the quality assurance of all aspects of pharmaceutical drug development, formulation and the manufacturing process
: 1,2,3,4,5,6,7,8
Describe in detail analytical techniques employed to assure quality and safety during the drug development process and the quality, safety and efficacy of the finished drug product: 1,2,3,4,5,6,7,8
Demonstrate the relationship between the design of drug product formulation, properties of the formulation, in vitro behaviour and in vivo performance: 1,2,3,4,5,6,7,8
Apply the physicochemical principles underlying the formulation of various dosage forms to the extemporaneous preparation of medicines: 1,2,3,4,5,6,7,8
Describe the relevance of microbiology within healthcare practice, and the challenges presented by infection in the context of patient care: 1,2,3,4,5,6,7,8
Describe in detail the metabolic interrelationships of the various tissues and organs of the human body, including the role of hormones in the intergration of metabolism and the maintenance of homeostasis: 1,2,3,4,5,6,7,8
Explain the common techniques used in the analysis of biological data to arrive at safe and appropriate drug selection for a patient: 1,2,3,4,5,6,7,8
Interpret nationally and locally produced guidelines in the selection and recommendation of appropriate therapeutic regimens for patients: 1,2,3,4,5,6,7,8
Apply a methodical approach to, and demonstrate competence in, the supply of medicines, including controlled drugs, in light of relevant clinical, legal, ethical and pharmaceutical factors: 1,2,3,4,5,6,7,8
Demonstrate competence in pharmaceutical calculations related to pharmacology, pharmaceutics and pharmacy practice: 1,2,3,4,5,6,7,8
Demonstrate competence in the performance of laboratory techniques in the pharmceutical sciences and the analysis of data generated therein: 1,2,3,4,5,6,7,8
Communicate complex concepts effectively, both orally and in writing, in a manner that reflects professional practice: 1,2,3,4,5,6,7,8

Study hours

Large- and small-group teaching sessions: 200 hours
Skills-based practical work and placement activity: 200 hours
Directed private study: 500 hours
Non-directed private study, revision and assessment: 300 hours



School Rules

None

Description of Module Assessment

1: Laboratory Assessment weighted 18%
1st Cycle laboratory skills assessment
The laboratory assessment will comprise elements from multiple laboratory sessions during the 1st Cycle

2: Practical Assessment weighted 7%
1st Cycle practical skills assessment
The practical skills assessment will cover a variety of academic and professional skills-based tasks in Pharmacology Analysis.

3: Exam weighted 25%
Cycle 1 examinations
The Cycle 1 exams contain online tests of Paper1 (MCQ) (47.5%) and Paper2 (LAQ)(47.5%). Low stake assessments (5%) will be incorporated within this component. Examples of low stake assessments may include MCQs, quizzes and other similar forms of assessment covering a variety of key topics from Cycle 1.

4: Laboratory Assessment weighted 12%
2nd cycle laboratory skills assessment
The laboratory assessment will comprise elements from multiple laboratory sessions during the 2nd Cycle

5: Practical Assessment weighted 13%
2nd cycle practical skills assessment
The practical skills assessment will cover a variety of academic and professional skills-based tasks in Microbiology and Pharmacy practice.

6: Exam weighted 25%
Cycle 2 examinations
The Cycle 2 exams contain online tests of Paper1 (MCQ) (47.5%) and Paper2 (LAQ)(47.5%). Low stake assessments (5%) will be incorporated within this component. Examples of low stake assessments may include MCQs, quizzes and other similar forms of assessment covering a variety of key topics from Cycle 2.

7: Professional Development weighted 0%
Professional skills development
The Professional Development assessment will include CPD activities, competency assessment in pharmacy practice (including calculations and communications skills), case studies in ethics, and evidence of professionalism measured by Professional Activity Credits

8: Mixed Exam weighted 0%
End of year synoptic assessment
This assessment will comprise both group work and individual assessment. It will potentially cover all topics studied during the year, but will focus in particular on demonstrating understanding of the integration of those topics.