PHA-10032 - Introduction to Pharmaceutical Sciences
Coordinator: Johannes Reynisson Room: HORBM1.08 Tel: +44 1782 7 33985
Lecture Time: See Timetable...
Level: Level 4
Credits: 30
Study Hours: 300
School Office:

Programme/Approved Electives for 2022/23

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

n/a

Barred Combinations

None

Description for 2022/23


Aims
To provide an introduction to the chemistry, formulation and pharmacological and related subjects in the context of pharmaceutical sciences.

Intended Learning Outcomes

Identify common organic molecular structures and functional groups and write suitable reaction mechanisms for their interconversion: 2,3
Demonstrate knowledge of the basic thermodynamic and kinetic principles that govern the progress of chemical reactions both in vitro and in vivo: 2,3
Recognise how the structural features, stereochemistry and functional groups responsible for chemical and physical properties can influence the biological activity of molecules and, hence, the drug design process: 2,3
Acquire data from experiments, analyse and manipulate it using appropriate techniques, and apply methods for the presentation of data, including statistical analysis and choosing an appropriate method of presentation: 1
Recognise and apply appropriately the health and safety practices and policies required for a wide range of pharmaceutical science laboratory classes, including appropriate documentation: 1
Demonstrate and apply the appropriate levels of numeracy and IT skills requisite for further study in pharmaceutical science at all levels to perform common scientific calculations with precision and accuracy: 1,2,3
Describe the structure, fundamental biopharmaceutical properties and transport across biological membranes, distinguishing the roles played by the lipid and protein components of the membrane: 2,3
Describe the process of drug discovery and development, from target disease to the design and isolation of a pure lead compound for formulation to provide a medicinal product: 2,3
Describe the underlying principles of quantitative pharmacology in relation to small organic molecules and biomolecules as therapeutic agents, and its relationship to biological processes and pharmaceutical products: 2,3
Describe the basic aspects of formulation science related to drug distribution and drug action that are important in drug design and development, including the relative merits and demerits of the available forms: 2,3

Study hours

Teaching: 68 hours lectures and workshops, lab debrief sessions and calculations classes; 35 hours chemical science (27) and pharmacology (8) labs
Directed: 97
Independent: 100

School Rules

None

Description of Module Assessment

1: Laboratory Practicals weighted 60%
Laboratory skills assessment
The laboratory assessment will comprise elements from multiple laboratory sessions focused on chemical sciences and pharmacology during the module. These are: - Chemical Sciences: one formative and one summative laboratory pre-lab & pro-forma document - one full laboratory report (2000 words) based on three separate laboratory sessions. This 40% of the module component mark, which is split as 30% of the laboratory report and 10% for the proforma. - Pharmacology: three online quizzes. 60% of the module component mark.

2: Exam weighted 20%
Examination 1 (end of Semester 1) - 90 minutes
Multiple choice questions examinations of 1 hour 30 minutes which covers content delivered in Semester 1. This assessment is examined at the end of Semester 1. Practice material will be provided prior to the examination to assist students with preparation. Small-stakes assessments will be retained in this component and will comprise no more than 10% of the overall component mark.

3: Exam weighted 20%
Examination 2 (end of Semester 2) - 90 minutes
Multiple choice questions examinations of 1 hour 30 minutes which covers content delivered in Semester 2. This assessment is examined at the end of Semester 2. Practice material will be provided prior to the examination to assist students with preparation. Small-stakes assessments will be retained in this component and will comprise no more than 10% of the overall component mark.