Programme/Approved Electives for 2025/26
None
Available as a Free Standing Elective
No
Understanding how your genome sequence is different from other individuals and has an impact on gene and protein expression, predisposition to diseases and response to therapies is the core principle of Precision Medicine. Today, due to the reduction in costs of genotyping and increasing availability of multi-omics technologies, this has become a reality. The key aim of this module is to allow you to explore and build understanding in multi-omics technologies and how they can be applied in healthcare to provide precision medicine.
Aims
This module will introduce students to the concept of personalised/precision medicine and the application of emerging omics technologies to the clinical setting.
Intended Learning Outcomes
Critically discuss the principles of Precision Medicine and debate how multi-omics technologies can contribute to the development of a patient-tailored treatment.: 2Explore the applications and critically compare the limitations of a range of multi-omics technologies.: 2Evaluate and apply principles of precision medicine to different disease areas, demonstrating an in-depth knowledge of current and future clinical applications.: 1,2
Lectures (24 hrs)Journal Clubs (6 hrs)Assignment Formative Feedback Online Drop-in Sessions (10 hrs)Independent Studies (110 hrs)- Pre-reading/reviewing module content (12 hrs)- Preparation for journal clubs (15 hrs)- Module assignments (60 hrs)- Independent/Additional Reading (23 hrs)
Description of Module Assessment
1: Essay-Plan weighted 20%Detailed Mind MapA detailed mind-map (250 words) to develop an approach for stratifying patients for treatment
of an assigned disease specified in the assessment brief or for stratifying patients into sub-categories of the assigned disease specified in the assessment brief.
The student should consider how they can apply their knowledge to stratify patients. This includes considering which factors (environmental/genetic) influence disease prognosis or prediction or treatment outcomes. They should suggest appropriate tools ('Omics/biomarkers/prognostic modelling) to support their approach.
2: Essay weighted 80%Written AssignmentA 2500 word written assignment to develop an approach for stratifying patients for treatment of
a disease of choice or for stratifying patients into sub-categories of a disease of choice (different to the disease specified in Assessment 1).
They should consider how genetic and/or environmental factors may contribute to prognosis or
therapeutic outcome and what tools/techniques ('omics and biomarkers) can be used to help
identify whether these genetic and environmental differences exist between patients.