LSC-30104 - Models in Neuroscience Research
Coordinator: Muriel Desbois
Lecture Time:
Level: Level 6
Credits: 15
Study Hours: 150
School Office: 01782 734414

Programme/Approved Electives for 2026/27

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

None

Barred Combinations

No

Description for 2026/27

In this module, you will learn how computational approaches, cultured cells and animal models are used in research to study different neuroscience topics. Lecturers will use their own research interests and research models to demonstrate their use. You will learn the advantages and limitations of several model systems, their ethical considerations, and how to use this knowledge to investigate neurobiological questions.
Through lectures and tutorials, using real research examples, you will learn to identify appropriate model systems for various experiments and critically evaluate research articles that use computational approaches, cell cultures and animal models.

Aims
This module aims to provide students with a comprehensive understanding of animal models used in neuroscience research. By learning the advantages, limitations, and ethical considerations associated with these models, students will understand the approaches used for neurobiology research.

Intended Learning Outcomes

Evaluate the advantages and limitations of model systems used to study neuroscience: 1,2
Apply knowledge of model systems to neurobiological investigations: 1,2
Discuss the ethical considerations of different model systems in neuroscience research: 1,2
Compare and contrast various animal models and determine the most appropriate model to address a specific research question: 2

Study hours

Active learning:
10 x 1 hour lectures introducing model systems and research topics
10 x 2 hour tutorials to discuss and critique select research articles and support developing final assessment.
10 x 5 hours preparation for tutorials (engagement with directed reading and other tutorial materials).
Independent study:
40 hours of wider independent study around module topics
30 hours preparation of final assessment

School Rules

None

Description of Module Assessment

1: Essay weighted 25%
Essay on the use of a selected neuroscience model systems to answer a specific scientific question (750 words)
This first assessment will help students engage with a research question and start critically thinking about the use of animal models in neuroscience research. This will serve as a foundation for the second assessment. A set of 3 research questions will be set and given to students to answer; each question fits a different aspect of neuroscience. Students will be required to select one question, which they will keep for the second assessment too, and to critically evaluate and discuss the use of at least one relevant model, which can be used to answer the question they selected. The essay should include a discussion of each model’s application, strengths, and limitations, as well as the ethical implications of using those models, regarding the question selected. Additionally, students must propose suitable experimental approaches for each model to effectively address the research question. Arguments and proposals must be supported by appropriate academic literature. The essay will be 750 words.

2: Portfolio weighted 75%
1,750 word discussion of neuroscience model systems to answer a specific scientific question
A set of 3 research questions will be set and given to students to answer; each question fits a different aspect of neuroscience. Students will use the same question as they selected from the first assessment (though if they wish to change they can), and to critically evaluate and discuss the use of at least FOUR relevant models, which can be used to answer the question they selected. The proposal should include a discussion of each model’s application, strengths, and limitations, as well as the ethical implications of using those models, regarding the question selected. Additionally, students must propose suitable experimental approaches for each model to effectively address the research question. Arguments and proposals must be supported by appropriate academic literature. The essay will have a word count of 1750 words.