Programme/Approved Electives for 2025/26
None
Available as a Free Standing Elective
No
Cell to cell communication is fundamental for multi-cellular organisms as cells are required to communicate with their environment and among themselves in order to respond to particular stimuli. Such response is then integrated at the system level for the proper functioning of the organism. Not surprisingly, dysregulation of cellular communication causes many diseases including cancer. Cell to cell communication involves many signalling pathways. These signalling pathways regulate multiple cellular processes by acting through sensors to stimulate molecules that are responsible for controlling different important cellular processes. This module explores these signalling pathways and provides details on their molecular components and their mode of action. The module also places an emphasis on independent study and further develops skills in the acquisition, analysis and written communication of scientific information.
Aims
The aims of this module are to give students a thorough background in the signalling mechanisms by which mammalian cells are regulated. The module provides a detailed description of the main modes of cell-cell communication, the major classes of signalling molecules and the receptor types upon which they act. It then focuses on the molecular details of these receptors and their associated signal transduction pathways.
Talis Aspire Reading ListAny reading lists will be provided by the start of the course.http://lists.lib.keele.ac.uk/modules/lsc-20085/lists
Intended Learning Outcomes
explain the main modes of cell-cell communication, the major classes of signalling molecules and the receptor types upon which they act: 2describe the mode of action of receptors and discuss how they can activate major signalling pathways: 1,2evaluate the involvement of cell signalling pathways in disease processes and how these pathways are targeted for therapeutic intervention in a named disease: 1,2analyse and critically evaluate the context and results of primary scientific literature related to cell signalling: 1locate and retrieve information from scientific literature: 1,2
Active learning:12 hours of tutorials/discussion activities supporting asynchronous content2 hours of tutorial related to the literature review assessment and exam preparation14 x 4 hours engagement with asynchronous contentIndependent study:3 hours completion of Exam39 hours completion of literature review38 hours independent study; exam preparation/revision and engaging with directed reading
Description of Module Assessment
1: Literature Review weighted 50%1500 word Literature review1500 word Literature review based on the involvement of cell signalling pathways in disease
processes and how these pathways are targeted for therapeutic interventions. Titles will be
related to core topics covered in the module and released in week 11/12 of the semester to be
submitted in the exam period, with students required to sign-up for specific titles from a list of
options.
2: Exam weighted 50%Unseen exam - multiple choice and short answer questionsThe unseen exam will consist of multiple-choice and short-answer questions assessing lecture-based material. While the exam is designed to take approximately 1 hour, all students will be allocated 2 hours to ensure an inclusive and accessible assessment experience. Students will be permitted to take a double-sided A4 memory prompt of notes with them to the exam.