LSC-20015 - Molecular, Cellular and Structural Immunology
Coordinator: Annette K Shrive Room: HUX212A Tel: +44 1782 7 33419
Lecture Time: See Timetable...
Level: Level 5
Credits: 15
Study Hours: 150
School Office: 01782 734414

Programme/Approved Electives for 2020/21


Available as a Free Standing Elective






Barred Combinations


Description for 2020/21

In this module you will explore how the mammalian body copes with infection by various pathogens. This includes addressing the cellular basis of the immune system and the generation and selection of the immune repertoire. You will also explore functional insights on immune protein structure and pathogen structure, including viruses and bacteria. You will also address the use of antibodies, accessing and using protein databases, and explore the structure/function relationship of proteins.

The aims of the course are to consider how the mammalian body copes with infection by various pathogens, to understand the cellular basis of the immune system and the generation and selection of the immune repertoire including the role of apoptosis, to consider the structure and function of immune proteins, viruses, bacteria and other pathogens, and to develop subject-based IT skills.

Talis Aspire Reading List
Any reading lists will be provided by the start of the course.

Intended Learning Outcomes

Discuss and explain the key concepts of the mammalian immune system repertoire and its role in combating infection: 3
Describe and critically evaluate the generation and selection of the immune repertoire: 3
Explain the cell and molecular biology of apoptosis: 3
Explain key concepts of the structure and function relationship with reference to proteins of the immune system: 3
Explain in detail the key concepts of the structure, function and immune system recognition of viruses, bacteria and other pathogens: 3
Explain and critically evaluate analytical methods used based on antibodies: 2
Locate and retrieve scientific information, protein sequences and protein structures, and manipulate and present data retrieved from protein databases: 1
Describe in detail the cells mediating the immune response: 3

Study hours

22 Hours Lectures
30 Hours Laboratory classes
2 Hours Exam
96 Hours Private study/preparation for assessment

School Rules


Description of Module Assessment

1: Report weighted 10%
IT report
Short report or proforma based on data retrieved from scientific databases

2: Essay weighted 30%
Length 1500 words, addressing the practical use of antibodies in labs and research.

3: Open Book Examination weighted 60%
Online open book exam
The paper will be released on KLE as a word document at 9am on the morning of the exam. Section A of the paper (60%) will contain compulsory, short answer questions and Section B (40%) will contain a choice of 1 out of 3 essay-based questions. Students should answer each question using Word, clearly labelling each question as they provide their answers. Work will be submitted to Turnitin no later than 5pm on the day of release. International students will be asked to notify the School if they need an extension due to different time zones. Although students have been given significant time to complete this exam script, we expect most students to spend no more than 2 hours. Answers should be as accurate and concise as possible. For short-answer questions, students should pay careful attention to the number of points that each question is worth. In general, we would expect only one or two sentences for each point. For essay-based questions, typical answers would be in the range of 500-750 words per question. We recommend that students do not exceed 750 words.