Programme/Approved Electives for 2022/23
Available as a Free Standing Elective
In this module you will explore how the mammalian body copes with infection by various pathogens. This includes addressing the cellular basis of the immune system and the generation and selection of the immune repertoire. You will also explore functional insights of immune protein structure and pathogen structure, including viruses and bacteria, and key concepts of the structure, function and immune recognition of pathogens. Within laboratory and workshop sessions, you will address the use of antibodies in the laboratory setting, and accessing and using protein databases and further explore the structure/function relationship of proteins.Please note that either LSC-20015 or LSC-20073 is a pre-requisite for taking the module LSC-30036.
Talis Aspire Reading ListAny reading lists will be provided by the start of the course.http://lists.lib.keele.ac.uk/modules/lsc-20015/lists
The aims of the course are to consider how the mammalian body copes with infection by various pathogens, to understand the cellular basis of the immune system and the generation and selection of the immune repertoire including the role of cell death, to consider the structure and function of immune proteins, viruses, bacteria and other pathogens, and to develop subject-based IT skills.
Intended Learning Outcomes
discuss and explain the key concepts of the mammalian immune system repertoire and its role in combating infection: 2describe and critically evaluate the generation and selection of the immune repertoire: 2explain the cell and molecular biology of cell death: 2explain key concepts of the structure and function relationship with reference to proteins of the immune system: 2explain in detail the key concepts of the structure, function and immune system recognition of viruses, bacteria and other pathogens: 2explain and critically evaluate analytical methods used based on antibodies: 1locate and use scientific information, protein sequences and protein structures from protein databases: 2describe in detail the cells mediating the immune response: 2
10x 1 hour tutorials4x 1 hour workshops11x 3 hours engagement with asynchronous content2 hours completion of examination (9-5 format)101 hours private study to include completion of practical report
1: Laboratory Report weighted 40%
Description of Module Assessment
Practical report based on experimental laboratory workLength 2500 words. The raw data for the lab report may involve some team work. The write-up, analysis and presentation (e.g. tables, graphs etc) of the data is carried out individually.2: Open Book Examination weighted 60%
Online open book examThe paper will be released on KLE as a word document at 9am on the morning of the exam. Section A of the paper (60%) will contain compulsory, short answer questions and Section B (40%) will contain a choice of 1 out of 3 essay-based questions.
Students should answer each question using Word, clearly labelling each question as they provide their answers. Work will be submitted to Turnitin no later than 5pm on the day of release. International students will be asked to notify the School if they need an extension due to different time zones.
Although students have been given significant time to complete this exam script, we expect most students to spend no more than 2 hours. Answers should be as accurate and concise as possible. Additional time has been given simply to provide a more flexible and inclusive approach, for example, required for students with disability, specific learning requirements, caring responsibilities and so on.
For short-answer questions, students should pay careful attention to the number of points that each question is worth. In general, we would expect only one or two sentences for each point.
For essay-based questions, typical answers would be in the range of 500-750 words per question. We recommend that students do not exceed 750 words per essay-based question as we will be assessing the quality of the answer, not the quantity.