Programme/Approved Electives for 2025/26
None
Available as a Free Standing Elective
No
In this module you will explore how the mammalian body copes with infection by various pathogens. This includes addressing the cellular basis of the immune system and the generation and selection of the immune repertoire. You will explore functional insights into immune protein structure and pathogen structure, including viruses and bacteria. You will also address the use of antibodies, accessing and using protein databases, and explore the structure/function relationship of proteins.
Aims
The aims of the course are to consider how the mammalian body copes with infection by various pathogens, to understand the cellular basis of the immune system and the generation and selection of the immune repertoire including the role of cell death, to consider the structure and function of immune proteins, viruses, bacteria and other pathogens, and to consider the use of antibodies in immunological techniques.
Talis Aspire Reading ListAny reading lists will be provided by the start of the course.http://lists.lib.keele.ac.uk/modules/lsc-20015/lists
Intended Learning Outcomes
discuss and explain the key concepts of the mammalian immune system repertoire and its role in combating infection: 2describe and critically evaluate the generation and selection of the immune repertoire: 2explain the cell and molecular biology of cell death: 2explain key concepts of the structure and function relationship with reference to proteins of the immune system: 2explain in detail the key concepts of the structure, function and immune system recognition of viruses, bacteria and other pathogens: 2explain and critically evaluate analytical methods used based on antibodies: 1locate and use scientific information, protein sequences and protein structures from scientific databases: 1,2describe in detail the cells mediating the immune response: 2communicate the results of experimental investigations effectively in written form in a scientific laboratory report: 1
14 hours of tutorials/discussion activities supporting asynchronous material and assessment3x 2 hour workshops9x 5 hours asynchronous (on demand) activities (engagement with pre-recorded materials)2 hours exam83 hours independent study; preparation for in-course assessment (practical report), and revision and engagement with directed reading to support end-of-semester exam
Description of Module Assessment
1: Laboratory Report weighted 50%Practical report based on experimental laboratory workLaboratory report (maximum 2500 words) based on data collected in laboratory sessions delivered in LSC-20127, assessing the analysis and presentation (e.g. tables, graphs etc) of experimental data and an evaluation of outcomes in context to relevant literature, supported with additional workshops and tutorials
2: Exam weighted 50%Unseen exam - multiple choice and short answer questionsThe unseen exam will consist of multiple-choice and short-answer questions assessing lecture-based material. While the exam is designed to take approximately 1 hour, all students will be allocated 2 hours to ensure an inclusive and accessible assessment experience. Students will be permitted to take a double-sided A4 memory prompt of notes with them to the exam.