PHA-20020 - Immunology & Immunotherapy
Coordinator: Patricia Ragazzon Tel: +44 1782 7 34767
Lecture Time: See Timetable...
Level: Level 5
Credits: 15
Study Hours: 150
School Office:

Programme/Approved Electives for 2023/24

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

none

Barred Combinations

none

Description for 2023/24

This module provides an integrated and fully contextualised understanding of how the immune system works and how it can be harnessed for
therapeutic purposes. Topics such as biological
therapies, and cancer will be explored.
The students will study the cells and molecules of the innate and adaptive immune system, the development of lymphocytes, activation and antigen recognition. After this general introduction the students will learn about regulation of the immune system, autoimmune disorders, infection, and inflammation. After this section the students will sit a 120 minutes exam to monitor their learning.
The potential and limitations of harnessing the immune system will be studied in section B. Throughout this module, students will work on clinical case studies and will apply their gained knowledge developing a brochure related to specific diseases, treatment and side effects.

Aims
This module aims to provide an integrated and fully contextualised analysis of basic immunology, autoimmune diseases and therapies based on components of the immune system.

Talis Aspire Reading List
Any reading lists will be provided by the start of the course.
http://lists.lib.keele.ac.uk/modules/pha-20020/lists

Intended Learning Outcomes

Identify the components of the innate and adaptive immune system
: 1
Recognise and explain antigen-recognition by T and B lymphocytes
: 1
Identify and evaluate the implications of the regulation of the immune system and the conditions arising from faults in it
: 1
Discuss the role of microbiota in the development of the immune system
: 1
Describe in detail how antibody technology can be utilised in the treatment of chronic diseases
: 2
Recognise how different disease outcomes can be improved by harnessing components of the immune system
: 2
Interpret different side effects of immunotherapy: 2

Study hours

Active Learning:
Lectures: 20 hours
Interactive lectures: 8 hours
Seminars: 4 hours
Practical sessions (including in-semester / in-situ exam): 5 hours
Tutorials: 8 hour
Independent study: 105 hours

School Rules

None

Description of Module Assessment

1: Exam weighted 40%
In-semester Exam
In-situ exam covering innate & adaptive immune system, cytokines, disorders and microbiome (total duration: 2 hours long). This exam is composed by different types of questions, such as multiple choice, very short answer questions, long answer questions and/or case studies.

2: Assignment weighted 60%
Skills assessment
Students will develop a brochure (2000 words) aiming to inform clinicians the advances in the treatment of a given condition and the possible side effects of the therapy. This assessment is individual work.