LSC-30063 - Brain Disease
Coordinator: David N Furness Room: Hux171 Tel: +44 1782 7 33496
Lecture Time: See Timetable...
Level: Level 6
Credits: 15
Study Hours: 150
School Office: 01782 734414

Programme/Approved Electives for 2020/21

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

None

Barred Combinations



Description for 2020/21

The lectures in this module will review the occurrence, cause, aetiology and neuropathology of a number of common neurodegenerative diseases and neurobiological conditions. The lecture material will be complemented by clinical and research presentations and problem based learning classes which will stress the clinical aspects of neurodegenerative disease. Skills aquired include use of literature and internet research methods, and evaluation of individual case histories relating to specific clinical conditions relevant to the lecture material. The module contributes to the programme as a whole by offering detailed learning on neurological conditions not available elsewhere in the programme, but building on student knowledge already acquired. This module will be of benefit to you by enhancing your knowledge base, offering you structured assistance in acquiring new knowledge and a flavour of diseases that you are highly likely to encounter and that could underpin future career aspirations. These diseases are socially and economically important, both personally and in the population as a whole.

Aims
To use knowledge of the symptoms and underlying causes of brain diseases and disorders to further understand the workings of the brain and central nervous system in health and disease.

Intended Learning Outcomes

Explain what is a stroke in relation to the brain¿s blood supply, and what are the typical neurological signs resulting from common or example strokes: 1,2
Recognise the normal anatomy and operation of the brain¿s ventricular system and how blockages or infections can lead to hydrocephalous or meningitis: 1
Explain the role of aberrant proteins in Parkinson¿s and Huntingdon¿s disease: 1,2
Explain the significance of demyelination/remyelination and experience clinical presentations of MS including disease progression, diagnosis and treatment: 1,2
Define cell death in neurodegenerative disease: 1
Explain the concise neuropathology and aetiology of Alzheimer¿s disease: 1,2
Describe partial and generalised seizures in epilepsy and their neurobiological basis: 1,2
Review current understanding of the pathophysiological mechanisms underlying cerebral palsy, and developmental hypoxia in the mammalian brain: 1
Explain the potential role of the basal ganglia in schizophrenia pathology, and symptomatic expression: 1,2

Study hours

17 hours lectures
3 hours clinical/research presentations
3 hours PBL tutroials (compulsory)
2-hour examination
30 hours in-course assessment (private study and writing)
95 hours private study

School Rules

Biology students may not take this module with LSC-30003 Applied Insect Ecology.

Description of Module Assessment

1: Open Book Examination weighted 75%
Online open book exam
The paper will be released on KLE as a Word document at 9am on the morning of the exam. The paper consists of essay based questions, The student will select two out of a chocie of five. Students should answer each question using Word, clearly labelling each question as they provide their answers. Work will be submitted to Turnitin no later than 5pm on the day of release. International students will be asked to notify the School if they need an extension due to different time zones. Although students have been given significant time to complete this exam script, we expect most students to spend no more than 2 hours. Answers should be as accurate and concise as possible. For essay-based questions, typical answers would be in the range of 500-750 words per question. We recommend that students do not exceed 750 words per essay-based question as we will be assessing the quality of the answer, not the quantity.

2: Case Study weighted 25%
Problem based learning
Students are expected to work online together in groups of up to 10 to evaluate a case study and then independently answer a questionnaire based on the topic they have studied as a group.