Physics & Astrophysics
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- Arumugam Mahendrasingam
My first degree (BSc, Honours) in Physics was from University of Sri Lanka (Colombo Campus) in 1976. Subsequently I joined the Physics Department at University of Jaffna, Sri Lanka. I came to Keele as a PhD student in 1979 and completed PhD on “X-ray fibre diffraction studies on the polymorphism of DNA and its synthetic analogues” under the supervision of Professor Watson Fuller in 1983. I was appointed as a Research Fellow in 1982 and subsequently appointed as a Lecturer (Physics) in 1989. Later on I was promoted to Senior lecturer (1997) and Reader (2001).
The Keele Fibre Diffraction Group has an international reputation for the development and application of X-ray and neutron diffraction techniques in the investigation of molecular structure and organization in a wide range of naturally occurring and synthetic materials. As a member of Fibre Diffraction group, I have made major contribution to the development of time-resolved and microfocus X-ray techniques and to the development of neutron fibre diffraction. We also developed instrumentation for the beamlines at the Advanced Photon Source (USA) and Daresbury SRS to study the deformation of polymer materials.
My research activities in recent years are:
- application to time and spatially resolved x-ray diffraction techniques to investigate the structure property development in polymeric materials due to elongation flow;
- developing uniaxial and biaxial deformation techniques to process biodegradable polymers as alternatives to the conventional polymer materials produced from petrochemicals (collaboration with Innovia);
- the polymorphism associated with cocoa butter which is crucial to the high quality of chocolate confectionery (collaboration with Nestle);
- the application of time-resolved x-ray diffraction studies of solid state phase transitions in pharmaceutical compounds as a consequence of product processing, response to environmental stress, and the presence of plasticizers( collaboration with University of Minnesota).
Selected Publications
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2006. Investigation of the Multi-Step Dehydration Reaction of Theophylline Monohydrate Using 2-Dimensional Powder X-ray Diffractometry. Pharmaceutical Research, vol. 23(10), 2393-2404. doi>
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2005. Time resolved study of oriented crystallisation of poly(lactic acid) during rapid tensile deformation. Polymer , vol. 46(16), 6009-6015. doi>
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2004. Time resolved WAXS/SAXS observations of crystallisation in oriented melts of ultra high molecular weight polyethylene. Polymer , vol. 45(16), 5641-5652. doi>
Full Publications List show
Journal Articles
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2006. Investigation of the Multi-Step Dehydration Reaction of Theophylline Monohydrate Using 2-Dimensional Powder X-ray Diffractometry. Pharmaceutical Research, vol. 23(10), 2393-2404. doi>
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2005. Time resolved study of oriented crystallisation of poly(lactic acid) during rapid tensile deformation. Polymer , vol. 46(16), 6009-6015. doi>
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2004. Time resolved WAXS/SAXS observations of crystallisation in oriented melts of ultra high molecular weight polyethylene. Polymer , vol. 45(16), 5641-5652. doi>
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2004. Water-DNA interactions as studied by X-ray and neutron fibre diffraction. Philosophical Transactions of the Royal Society of London. doi>
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2003. Observations of structure development during crystallisation of oriented poly(ethylene terephthalate). Polymer, vol. 44(19), 5915-5925. doi>
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2002. Synchrotron studies of molecular reorganization prior to strain-induced crystallization in polymers. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 223, D41. link>
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2002. Time-resolved x-ray diffraction of biaxial deformation of polymer materials. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 223, D26-D27. link>
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2001. Journal of Applied Polymer Science. Real-Time FTIR and WAXS studies of drawing behaviour of poly(ethylene terephthalate)films, vol. 79(10), 0.
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2000. X-ray diffraction studies of polymers at high temporal and spatial resolution using synchrotron. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 219, U262. link>
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2000. Ultrasonic measurements related to evolution of structure in curing epoxy resins. PLASTICS RUBBER AND COMPOSITES, vol. 29(3), 109-118. link>
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1997. Structural variation in polymer materials at high spatial resolution. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 214, 168-POLY. link>
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1997. Variation in SAXS and WAXS from polymer materials under industrial processing conditions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 214, 163-POLY. link>
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1990. TIME-RESOLVED X-RAY FIBER DIFFRACTION STUDIES OF THE S-REVERSIBLE-B CONFORMATIONAL TRANSITION IN THE POLY [D(G-C)] POLY [D(G-C)] DOUBLE HELIX. INSTITUTE OF PHYSICS CONFERENCE SERIES, 225-236. link>
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1990. X-RAY AND NEUTRON HIGH ANGLE FIBER DIFFRACTION STUDIES IN THE DETERMINATION OF HYDRATION AND IONIC STRUCTURE AROUND DNA. INSTITUTE OF PHYSICS CONFERENCE SERIES, 237-248. link>
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1990. X-RAY AND NEUTRON-DIFFRACTION STUDIES OF THE STRUCTURE OF PEEK. INSTITUTE OF PHYSICS CONFERENCE SERIES, 213-224. link>
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1986. X-ray high-angle fibre diffraction studies of nucleic acid structure using the Daresbury Synchrotron Radiation Source. Biochem Soc Trans, vol. 14(3), 553-557. link>
Other
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1996. DNA hydration studied by neutron fiber diffraction. Basic Life Sci (vol. 64, pp. 345-358). link>
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1996. Time-of-flight Laue fiber diffraction studies of perdeuterated DNA. Basic Life Sci (vol. 64, pp. 359-367). link>
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1993. COMPLEMENTARY X-RAY AND NEUTRON FIBER DIFFRACTION STUDIES OF THE DISTRIBUTION OF WATER AND CATIONS AROUND THE A-DNA DOUBLE HELIX. WATER-BIOMOLECULE INTERACTIONS (vol. 43, pp. 235-238). link>
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1993. ISOTHERMAL CRYSTALLIZATION OF BIAXIALLY ORIENTED POLY(ETHYLENE-TEREPHTHALATE) FILM. CRYSTALLIZATION OF POLYMERS (vol. 405, pp. 577-580). link>
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1993. THE LOCATION OF IONS AND WATER AROUND THE D CONFORMATION OF DNA. WATER-BIOMOLECULE INTERACTIONS (vol. 43, pp. 231-234). link>
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1990. TIME-RESOLVED X-RAY FIBER DIFFRACTION STUDIES OF THE S-REVERSIBLE-B CONFORMATIONAL TRANSITION IN THE POLY [D(G-C)] POLY [D(G-C)] DOUBLE HELIX. NEUTRON AND X-RAY SCATTERING : COMPLEMENTARY TECHNIQUES (vol. 101, pp. 225-236). link>
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1990. X-RAY AND NEUTRON HIGH ANGLE FIBER DIFFRACTION STUDIES IN THE DETERMINATION OF HYDRATION AND IONIC STRUCTURE AROUND DNA. NEUTRON AND X-RAY SCATTERING : COMPLEMENTARY TECHNIQUES (vol. 101, pp. 237-248). link>
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1990. X-RAY AND NEUTRON-DIFFRACTION STUDIES OF THE STRUCTURE OF PEEK. NEUTRON AND X-RAY SCATTERING : COMPLEMENTARY TECHNIQUES (vol. 101, pp. 213-224). link>

