| Abstract |
Applications are invited for this 4 year BBSRC Collaborative Industrial PhD studentship to commence as soon as possible. This studentship will be based at Keele University in the Research Institute for the Environment, Physical Sciences and Applied Mathematics (EPSAM), under the joint supervision by Dr KP Lam (EPSAM) and Professor JB Richardson (Institute for Science & Technology in Medicine) at the RJAH Orthopaedic Hospital, Oswestry.
Keele’s collaborative research with RJAH Orthopaedic Hospital, Oswestry, investigates new cell-based therapies using autologous cells and stem cells for treating patients with musculoskeletal injuries or diseases caused by sports or normal aging. For cartilage injuries, for example, the procedure typically involves taking a sample of cartilage from which to isolate chondrocytes, culturing them in the laboratory to induce proliferation, and then transplanting the cells into the site of injury. The clinical success and quality of repair tissue which forms is believed to depend on the activity and phenotype of the cells implanted. Based on so-called “omic” approaches, this project will develop automated technologies for analysing and quantifying cell phenotype and determine how this changes in different environmental conditions. Integrated data analysis for multiple imaging modalities will also be developed, enabling, for example, correlations with clinical outcome in an attempt to develop predictors of success.
More details in 'Supplementary Information'. |
Keele University
