School of Life Sciences  
 
 
LSC-10027 Metabolism: Major Metabolic Pathways  
Co-ordinator: Prof Chris Exley    Room: LJ0.06, Tel:34080  
Teaching Team: Mr I  Wright, Mrs Janet  Norton, Mrs Deborah  Goodall, Mrs Lisa  Smith, Mrs Linda  Flynn, Dr David  Watson, Dr Mark  Skidmore, Mrs Susan  Andrews  
Lecture Time: See Timetable...  
Level: 1 Credits: 15 Study Hours: 150  
School Office: Tel: 01782 734414
 
 
 
Programme/Approved Electives for
None
Available as a Free Standing Elective
No
Prerequisites
UNIVERSITY ENTRY CRITERIA

Barred Combinations
None
Description

All living things are packets of energy and the challenge of life and living is how energy can be used and controlled effectively. Human beings derive most but not all of their energy from diet, the processing of all that we eat and drink. How we use and control energy is essentially described by our metabolism and this is the subject of this module. We find that the human body cycles and recycles energy more effectively than any machine or government energy policy. We are experts in using energy effectively, conservatively and creatively. Sometimes something goes wrong in our energy cycling and this leads to metabolic disorders including conditions as seemingly diverse as obesity and neurological disease and some examples of such are included in the module. Overall we will learn and appreciate just how important energy cycling is in the effective human being and indeed all life forms. There is little more important in biochemical science than this and that is why this module provides the basis for biochemistry and biomedical sciences at Keele.
Aims
To provide an introduction to the major metabolic pathways by which fuels derived from food stuffs are further degraded to produce energy for the body. Catabolic and anabolic processes are covered, together with pathways designed to store energetic molecules for later use. The module also provides an introduction to other oxidative and energetic processes employed by cells.
Intended Learning Outcomes
Understand and demonstrate knowledge of the central role of metabolism in homeostasis, the key molecules involved and the thermodynamics controlling it will be achieved by assessments: 02
Understand and describe the progress and control of key metabolic pathways involving carbohydrates, including the maintenance of glucose homeostasis by glycogen metabolism will be achieved by assessments: 02
Understand and describe oxidative metabolic processes for the production of ATP, including enzyme complexes found in the mitochondria will be achieved by assessments: 02
Understand and describe catabolic and anabolic fatty acid metabolism, appreciating the significance of molecular structure in catabolic processes will be achieved by assessments: 02
Understand and describe both catabolic and anabolic processes in protein and amino acid metabolism, and the consequences of errors in amino acid metabolism will be achieved by assessments: 02
Understand and describe the integration of metabolic processes in the maintenance of homeostasis and the consequences of errors in metabolism with relevance to patient care and disease management will be achieved by assessments: 02
Demonstrate a high level of laboratory skills in the successful completion of appropriate manipulative practical exercises will be achieved by assessments: 01
Demonstrate a basic understanding of bioethics will be achieved by assessments:



Study hours
20 Lectures = 20h
5 Labs = 15h
5 Workshops = 15h
Private Study = 100h
Description of Module Assessment
01: Laboratory Report weighted 25%
Peptide Analyses
Laboratory Report
02: 2 Hour Exam weighted 75%
50% Short Answers 50% Structured Essays
2h Examination
Version: (1.06B) Updated: 03/Oct/2013

This document is the definitive current source of information about this module and supersedes any other information.