CHE-20021: Forensic Genetics

This module aims to provide the essential background knowledge of the molecular tools used for identifying individuals by DNA profiling and to build on this to describe some of the ways in which these tools are used in Forensic Science. The principle concepts in DNA profiling will be explored with the aim of extending the students understanding of human identification, its importance and application in the forensic context, analytical techniques and processes, population genetics and the presentation of DNA evidence in court.

Intended Learning Outcomes

Explain the principles and significance of nucleic acid hybridisation. will be achieved by assessments: 02, 03
Explain the principles of the polymerase chain reaction (PCR), DNA sequencing and DNA fingerprinting and their application in Forensic Science will be achieved by assessments: 02, 03
Describe and explain the development and application of LCN DNA-typing and its advantages and limitations regarding degradation and contamination. will be achieved by assessments: 01, 03
Explain the principles of the Human Genome Project. will be achieved by assessments: 03
Show a working knowledge of population genetics; calculate profile frequencies, evaluate their statistical significance and appreciate how to present this appropriately as an expert witness in court will be achieved by assessments: 01, 03
Critically evaluate the significance of different sources of DNA and appropriate approaches to collection, storage and analysis of the samples with reference to contamination avoidance procedures will be achieved by assessments: 01, 02, 03
Differentiate and critically assess types of polymorphism and DNA lineage markers and their importance in a forensic context will be achieved by assessments: 01, 03

Study hours

Lectures 22 hours
Laboratory Classes 15 hours
Tutorials/problems classes 3 hours
Directed study 20 hours
Independent study 90

Description of Module Assessment

01: Exercise weighted 20%

Skills tests
Assessment (1-hour class test and 1 problem sheet calculation based on a 1-hour problem class) testing the knowledge of the material and problem solving skills

02: Laboratory Assessment weighted 30% (min pass mark of 40)

Lab reports and lab book
Students will complete 1 report (1500 words) based on the practical classes and submit a lab book

03: 2 Hour Unseen Exam weighted 50% (min pass mark of 30)

Examination
2 hour unseen written examination

Version: (1.06B) Updated: 03/Mar/2013

This document is the definitive current source of information about this module and supersedes any other information.