School of Physical and Geographical Sciences  
 
 
CHE-20001 Organic Synthesis and Chirality  
Co-ordinator: Dr Michael Edwards   Tel:33252  
Teaching Team: Dr Graeme  Jones, Mrs Monica  Heaney Dr Katherine  Haxton Miss Nicola  Jervis Prof Jim  Howell Miss Laura  Hancock Dr Matthew  O'Brien  Mei  Shi  Joseph  Harrity  Nigel  Young  
Lecture Time: See Timetable...  
Level: 2 Credits: 15 Study Hours: 150  
School Office:
 
 
 
Programme/Approved Electives for

None

Available as a Free Standing Elective

No

Prerequisites

Successful completion of Level 1 modules in Chemistry or equivalent

Barred Combinations

None

Description

This is a core module for all chemistry and medicinal chemistry degree programmes at Keele and covers key topics in organic chemistry which highlight how chemical processes can be used to synthesize complex organic molecules. Concepts including stereochemistry and isomerism, and synthetic methodology using functional group interconversion and retrosynthesis are taught in an integrated manner through lectures, laboratory practicals and problem classes.

Aims

1. To develop, expand upon and connect key concepts in organic chemistry to provide a deeper understanding of the synthesis and properties of organic molecules.
2. To develop experimental and analytical laboratory skills
3. To develop problem solving and scientific writing skills.

Intended Learning Outcomes

Describe the origin, physical and chemical properties of enantiomers, diastereoisomers and conformational isomers will be achieved by assessments: 1,2,3,4
Describe the chemistry of organic molecules containing reactive functional groups and apply functional group interconversions in the design and synthesis of organic molecules will be achieved by assessments: 1,2,4
Apply the principles of mechanism in organic chemistry to solve problems in organic synthesis will be achieved by assessments: 1,3,4
Describe the properties and chemistry of heteroaromatic molecules will be achieved by assessments: 1,2,3,4
Apply retrosynthetic methodology to plan the synthesis of selected organic molecules will be achieved by assessments: 1,4
Undertake database/literature searches for appropriate material to present in the form of a poster will be achieved by assessments: 2
Apply practical skills to prepare organic molecules and rationalise the results of experiments through the analysis of spectral data will be achieved by assessments: 3
Demonstrate an understanding of laboratory practical skills and techniques in the synthesis of organic molecules will be achieved by assessments: 3
Keep an appropriately detailed contemporary laboratory diary recording the procedures, observations and results of experimental work will be achieved by assessments: 3

Study hours

Lectures: 20 hours
Class test: 1 hour
Laboratory practicals, poster session, problem classes and small group tutorials: 36 hours
Independent study, poster preparation: 93 hours




Description of Module Assessment

01: Class Test weighted 10%
In class test
Students answer unseen short answer questions that are closely related to a bank of questions provided to them

02: Poster Presentation weighted 10% (min pass mark of 40)
Poster presentation of organic chemistry topic
Students will prepare a poster on a topic related to the laboratory course that will require database and primary literature searches to locate information. Posters will be peer-marked by students and moderated by peer groups and staff.

03: Laboratory Assessment weighted 30% (min pass mark of 40)
In-laboratory proforma, laboratory diary and laboratory reports
In-lab proformas assessing laboratory skills to be submitted at the conclusion of each experiment (4 total). A contemporaneous laboratory diary is to be maintained for each experiment and marked periodically during the course. Proforma reports (assessing submitted samples and spectral data) will be submitted for each experiment, one of which will be a detailed report (maximum 600 words) containing full analysis of results and a professional experimental method.

04: Unseen Exam weighted 50% (min pass mark of 35)
2-hour unseen examination
The paper is split into two sections with a degree of choice in each section: Part A short answer questions, Part B long answer questions.


Version: (1.06B) Updated: 03/Mar/2013

This document is the definitive current source of information about this module and supersedes any other information.