Keele Undergraduates Co-author Publication on Antimalarial Drugs

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Posted on 16 December 2011

Five undergraduate students in the Schools of Life Sciences and Medicine have co-authored a study entitled "Synthesis and evaluation of a novel series of indoloisoquinolines as small molecule anti-malarial leads" in the journal Bioorganic & Medicinal Chemistry Letters.

This work was carried out as part of honours research projects or summer placements funded by the Wellcome Trust and Nuffield Foundation. The project, supervised by Dr Paul Horrocks and Professor Steve Allin, establishes key aspects of the structure-activity relationship of a library of synthetic indoloisoquinolines and their inhibitory effect on malaria parasite growth.

The work is also funded by the North Staffordshire Medical Research Institute.

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