ISTM

Education:

• 1999 DSc Physics in Medical Imaging, Kurchatov Institute of Atomic Energy, Moscow (Russia)
• 1985 PhD Radiobiology and Biophysics, Institute of Biophysics, Moscow (Russia)
• 1982 MS Physics at Moscow State Lomonosov University, Moscow (Russia)

Professional Experience:

• 1992 – 2005 Carolinas Medical Center, Charlotte, NC, USA - Director of the Biophysical Laboratory.
• 1990 – 2000 Kurchatov Institute of Atomic Energy, Moscow, Russia – Director of the Laboratory of Applied Biophysics
• 1988 – 1990, Kurchatov Institute of Atomic Energy, Moscow, Russia – Senior Research Scientist
• 1985 – 1988, Institute of Biophysics, Moscow, – Research Scientist
• 1982 – 1985, Institute of Biophysics, Moscow, Russia – Postgraduate Fellow

ISTM Research themes: 1. Clinical & Diagnostic Science 
2. Bioengineering & Therapeutics

Research Interests:

Professor Semenov’s research explores biomedical electromagnetic imaging and spectroscopy technologies, covering microwave, optical and electrical impedance techniques. These approaches allow for development of novel imaging modalities for rapid functional imaging including non-invasive assessment of tissue blood and oxygen content, circulation, tissue ischemia and infarction, malignancies, compartment syndrome in extremities and others.

Professor Semenov moved to Keele University in March 2006 from the Carolinas Medical Centre, Charlotte NC, USA, Within ISTM he is a member of the Clinical & Diagnostic Science research theme and also the Bioengineering & Therapeutics theme. He has active collaboration in his research with clinicians at the University Hospital of North Staffordshire including Dr Josep Sule Suso and Professor Monica Spiteri.

Current Projects:
Professor Semenov has recently focused on the research and development of microwave imaging technology for clinical use. This includes an allocation of proper funding sources, research and development of antennas, phased arrays, detectors and sensors, manufacture of prototype(s) of clinically viable systems, improvement of image reconstruction algorithms of diffraction tomography, image analysis, tissue electromagnetic spectroscopy and modelling and compliance with regulations. An interaction of non-ionizing electromagnetic radiation with biological tissues, including cardiac excited tissues and bioelectromagnetics of such tissues, are other ongoing projects. His future focus is on combined, multimodality functional imaging, both for clinical use and small animal imaging.

Recent Publications
Semenov S.  “Microwave tomography: review of the progress towards clinical applications”. Philos Transact A Math Phys Eng Sci 367(1900):3021-3042 13 Aug 2009.

Egot-Lemaire S., Pijanka J., Sulé-Suso J., Semenov S. “Dielectric spectroscopy of normal and malignant human lung cells at ultra-high frequencies”. Phys Med Biol 54(8):2341-2357 21 Apr 2009.

Semenov S., Kellam J., Althausen P., Williams T., Abubakar A., Bulyshev A., Sizov Y. “Microwave tomography for functional imaging of extremity soft tissues: feasibility assessment”.  Phys Med Biol 52(18):5705-5719 21 Sep 2007.

Semenov S.Y., Bulyshev A.E., Abubakar A., Posukh V.G., Sizov Y.E., Souvorov A.E., Van den Berg P., Williams T. “Microwave tomographic imaging of the high dielectric contrast objects using different imaging approaches”, IEEE Trans. MTT, v. 53, No 7, July 2005.

Semenov S.Y., Posukh V.G., Sizov Y.E., Bulyshev A.E., Souvorov A.E., Nazarov A.G, Williams T.C, Repin P.N. “Microwave Tomographic Imaging of the Heart in Intact Swine”, J. of Electromagn. Waves and Appl., 2005.

Abubakar A., Van den Berg P.M., Semenov S.Y. “A robust iterative method for Born inversion”, IEEE Trans GRS, 2004, 42, 2, 342-354.

Abubakar A., Van den Berg P.M., Semenov S.Y. “Two- and Three-dimensional algorithms for microwave imaging and inverse scattering”, J. of Electromagn. Waves and Appl., 2003, 17, 2, 209-231.

Semenov S.Y., Bulyshev A.E., Posukh V.G., Sizov Y.E., Williams T.C., Souvorov A.E. “Microwave tomography for detection/imaging of myocardial infarction. 1. Excised canine hearts”, Annals of Biomedical Engineering, 2003, 31, 262-270.

Semenov S.Y., Svenson R.H., Boulyshev A.E., Souvorov A.E., Nazarov A.G., Sizov Y.E., Posukh V.G., Pavlovsky A., Repin P.N., Starostin A.N., Voinov B., Tatsis G.P., Baranov V.Y. “Three-dimensional microwave tomography: initial experimental imaging of animals”, IEEE Trans BME, 2002, 49, 1, 55-63.

Semenov S.Y., Svenson R.H., Posukh V.G., Chen W., Nazarov A.G., Sizov Y.E., Kassel J., Tatsis G.P. “Dielectrical spectroscopy of canine myocardium during ischemia and hypoxia at frequency spectrum from 100KHz to 6GHz”, IEEE Trans MI, 2002, 21, 6, 703-707.

Semenov S.Y., Simonova G.I., Starostin A.N., Taran M.G., Souvorov A.E., Bulyshev A.E., Svenson R.H., Nazarov A.G., Sizov Y.E., Posukh V.G., Pavlovsky A., Tatsis G.P. “Modeling of dielectrical properties of cellular structures in the radiofrequency and microwave spectrum. Electrically interacting vs non-interacting cells”, Annals of Biomedical Engineering, 2001, 29, 5, 427-435.

Bulyshev A.E., Semenov S.Y., Souvorov A.E., Svenson R.H., Tatsis G.P. “Computational modeling of the three-dimensional microwave tomography of the breast cancer”, IEEE Trans. BME, 2001, 1053-1056.

Semenov S.Y., Svenson R.H., Tatsis G.P. "Microwave spectroscopy of myocardial ischemia and infarction. 1. Experimental Study", Annals of Biomedical Engineering, 2000, 28, 1, 48-54.

Semenov S.Y., Svenson R.H., Bulyshev A.E., Souvorov A.E., Nazarov A.G., Sizov Y.E., Posukh V.G., Pavlovsky A., Tatsis G.P. "Microwave spectroscopy of myocardial ischemia and infarction. 2. Biophysical reconstruction", Annals of Biomedical Engineering, 2000, 28, 1, 55-60.

Semenov S.Y., Svenson R.H., Bulyshev A.E., Souvorov A.E., Nazarov A.G., Sizov Y.E., Posukh V.G., Pavlovsky A.V., Repin P.N., Tatsis G.P. "Spatial resolution of microwave tomography for detection of the myocardial ischemia and infarction. Experimental study on two-dimensional models", IEEE Trans MTT, 2000, 48, 4, 538-544.

Semenov S.Y., Bulyshev A.E., Souvorov A.E., Nazarov A.G., Sizov Y.E., Svenson R.H., Posukh V.G., Pavlovsky A.V., Repin P.N., Tatsis G.P. “Three dimensional microwave tomography: Experimental imaging of phantoms and biological objects”, IEEE Trans MTT, 2000, 48, 6, 1071-1074.

Souvorov A.E., Bulyshev A.E., Semenov S.Y., Svenson R.H., Tatsis G.P. “Two-dimensional computer analysis of a microwave flat antenna array for breast cancer tomography”, IEEE Trans MTT, 2000, 48, 8, 1413-1415.

Bulyshev A.E., Semenov S.Y., Souvorov A.E., Svenson R.H., Nazarov A.G., Sizov Y.E., Tatsis G.P. “Three dimensional microwave tomography. Theory and computer experiments in scalar approximation”, Inverse Problems, 2000, 16, 863-875