fryer_anthony - Keele University

Professor Anthony A Fryer

Title: Professor of Clinical Biochemistry
Phone: +44 (0)1782 554669
Email:
a.a.fryer@keele.ac.uk
Location: Institute for Science & Technology in Medicine, Keele University,
Guy Hilton Research Centre, Thornburrow Drive, Hartshill, Stoke-on-Trent ST4 7QB United Kingdom
Role: ISTM Research themes:
1. Clinical & Diagnostic Science
2. Infection, Inflamation & Immunity
Contacting me: By e-mail please.
Tony_Fryer_150x190

Prof Tony Fryer completed his PhD at Keele in 1991 following work as a research biochemist in Department of Clinical Biochemistry, at North Staffordshire Hospital NHS Trust. He became a Keele Honorary Lecturer in 1999, Hon Senior Lecturer in 2003, in which year he became a Consultant Clinical Biochemist and was made Head of the Department of Clinical Biochemistry the following year.

Appointed as Keele Professor of Clinical Biochemistry in the Institute for Science & Technology in Medicine in 2008, Prof Fryer has also been chair of the West Midlands Association of Clinical Biochemistry since 2009. His involvement in research and training through Keele and the WM Association includes supervision of higher degrees and trainee Clinical Biochemists, and a wide range of research grants and awards from national and regional funders such National Institute for Health Research, Medical Research Council, Engineering and Physical Sciences Research Council, Cancer Research UK, British Lung Foundation, and the former NHS Locally Organised Research Scheme. Prof Fryer is a member of the  Fetal Epigenetics Group, and has output over 150 peer-reviewed publications and 24 book chapters/reviews.

In October 2012 Prof Fryer will succeed Prof Gordon Ferns as interim Research Director for the University Hospital of North Staffordshire.

ISTM Research themes:

1. Clinical & Diagnostic Science
2. Infection, Inflamation & Immunity 

Research Interests:

•    Performing the right test in the right patient at the right time: Assessment of the appropriateness of pathology testing and impact of guidance.
•    The impact of maternal folate supplementation during pregnancy on fetal epigenome..
•    Genetic and environmental risk factors for skin cancer in renal transplant recipients: use of statistical modelling approaches to predict risk.

Proportion of appropriate requests from primary care for the glycosylated haemoglobin test. Figure illustrates that 40% of requests are inappropriate (green/red bars), that this proportion is increasing and that national guidance has had little impact.  

Proportion of appropriate requests from primary care for the glycosylated haemoglobin test. Figure illustrates that 40% of requests are inappropriate (green/red bars), that this proportion is increasing and that national guidance has had little impact.

Association of mean LINE-1 methylation, as a surrogate for global methylation, with cord plasma homocysteine concentration. Figure illustrates a significant inverse relationship (p=0.001, r= -0.69) between markers of global methylation and functional methyl group supply.  

Association of mean LINE-1 methylation, as a surrogate for global methylation, with cord plasma homocysteine concentration. Figure illustrates a significant inverse relationship (p=0.001, r= -0.69) between markers of global methylation and functional methyl group supply.