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Keele Fetal Epigenetics Research Group
The mother's health and nutrition is critical to the wellbeing of the unborn child. The Keele Epigenetics Group uses state-of-the-art analytical screening techniques to examine the effect of folic acid intake during pregnancy on the status of the fetal epigenome. This data will inform national policies regarding supplementation and maternal nutrition.
FEG Research Team
FEG academic and clinical research members:
- William E Farrell
Professor of Human Genomics at Keele University - Anthony A Fryer
Consultant Clinical Biochemist UHNS & Professor of Clinical Biochemistry at Keele University - Khaled MK Ismail
Consultant Obstetrician UHNS & Professor at Keele University - Peter W Jones
Professor of Statistics at Keele University - William D Carroll
Consultant Paediatrician at Derbyshire Childrens' Hospital - Richard D. Emes
Associate Professor in Bioinformatics at Nottingham University.
Epigenetic study makes TV and radio headlines
Posted on 02 February 2011
Groundbreaking work led by the Epigenomics team in ISTM gained wide media coverage at the start of 2011.
Epigenetics group makes top ten Obs & Gynae papers
Posted on 16 November 2010
Keele and UHNS's Epigenetics group has a paper published in 2008 that is now in the top ten cited publications in the British Journal of Obstetrics & Gynaecology.
FEG News Highlights
- Latest FEG publication in Epigenetics January 2011: "Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans”. Read the paper here.
- Comment on the group’s research in Epigenie – news on epigenetics – 29 November 2010.
- Latest FEG publication in Epigenetics August 2009: “LINE-1 DNA methylation is inversely correlated with cord plasma homocysteine in man: a preliminary study.” Read the paper here.
- Khaled Ismail presents research to date at FIGO World Congress of Gynecology & Obstetrics, Cape Town South Africa.
- Funding secured for three year study of fetal epigenomics from the World Cancer Research Fund (WCRF). Follow this link to read a summary of the project.
- Clinical researcher Tamer Nafee awarded best oral presentation prize in the RCOG International Congress of Obstetrics and Gynaecology.
- Publication released in British Journal of Obstetrics and Gynaecology: "Epigenetic control of fetal gene expression". Follow this link to read the paper.
- Correspondence on "Should folic acid fortification be mandatory?" published in the British Medical Journal in June 2007. Read the comments here (second response on the page).
- Clinical Scientist position funded by Egyptian Cultural Bureau in London.
- Funding secured for patient recruitment from the North Staffordshire Medical Institute.
