Biography

Dave Hoole graduated from Leeds University having obtained a degree in Agricultural Zoology and decided to pursue his interest in the immunology and diseases of lower vertebrates at the University of Sunderland where he obtained his PhD. He was initially appointed as a University Demonstrator at Keele University and, after a brief period as a post-doctoral research scientist, was offered a lectureship in the School of Life Sciences. During his period at Keele he has continued to develop his expertise in lower vertebrates and has specialised in the immunology of cultured fish, for example carp (Cyprinus carpio) particularly in relationship to parasitic diseases and water quality. He has presented numerous invited seminars to a range of national and international conferences and has established collaborative research projects with several national and international laboratories for example in France and China. His research activity has been funded by a range of national and international funding bodies including Marie Curie ITN Frameworks 5 and 7. Professor Hoole is currently co-ordinator of a 3.1 million euro EU research training work involving academic and industrial partners in the Netherlands, Denmark, Germany, Poland, UK and Norway. The Network called 'NEMO' employs 16 post-graduate and post-doctoral works and is investigating the use of bioethanol byproducts e.g. ß glucan as an immunostimulant of innate immune response in carp and the associated protection against a range of viral, bacterial and parasitological diseases.

Dave Hoole has published widely and regularly referees scientific manuscripts and grant applications. He co-authored a book published by Blackwell Sciences on the Diseases of carp and other cyprinid fishes which reflects the importance of this subject to world aquaculture, fisheries and the ornamental trade. In addition, he has extensive collaborations with the National Fish Diseases Laboratory of the Environment Agency, UK. This authority recognises the Freshwater Consultancy, 'Keele Water', established by Dr Hoole and an associate, Dr A.A. Savage, as having the appropriate knowledge to carry out fish health checks under the Salmon and Freshwater Fisheries Act 1975. Professor Hoole is an active member of the European Association of Fish Pathologists, British Society for Parasitology, Fisheries Society of the British Isles, and Institute of Fish Managers.

His research interest and expertise is also incorporated into the teaching programme at Keele University, where he teaches comparative immunology and a final-year module on Applied Fish Biology. In addition, he regularly gives guest lectures to a range of fisheries societies, angling clubs within the UK and international conferences.

Recent key publications

MACCARTHY, E., BURNS, I, IRNAZAROW, I., POLWART, A., GREENHOUGH, T.J., SHRIVE , A., & HOOLE, D. (2008) Serum CRP-like protein profile in common carp Cyprinus carpio challenged with Aeromonas hydrophila and Escherichia coli lipopolysaccharide. Developmental and Comparative Immunology, 32, pp. 1281-1289.

VIDAL, M, COLS, HOOLE, D. & WILLIAMS, G. T. (2008) Characterisation of cDNA of key genes involved in apoptosis in immune cells of common carp (Cyprinus carpio L.). Fish and Shellfish Immunology. 25, 494-507.

HOOLE, D. and WILLIAMS, G.T. (2004) The role of apoptosis in non-mammalian host-parasite relationships. pp. 13-14 in Host-Parasite Interactions edited by G.F. Wiegertjes & G. Flik. BIOS Scientific Publications.

HOOLE, D., LEWIS, J.W., SCHUMERACK, P.M.M., CHAKRAVARTHY, C., SHRIVE, A.K., GREENHOUGH, T.J. & CARTWRIGHT, J.R (2003) Inflammatory interaction in fish exposed to pollutants and parasites : a role for apoptosis and C reactive protein. Parasitology, 126, S71-S85.

HOOLE, D., BUCKE, D., BURGESS, P. & WELLBY, I. (2001) Diseases of Carp and other Cyprinid Fishes. Commissioned by Blackwell Scientific Pub.

e-mail: caep@keele.ac.uk
Last updated: 21 December 2009 10:43