Dr Anthony D.M. Curtis

Title: Senior Lecturer in Organic and Medicinal Chemistry
Phone: (+44) 01782 7 33040
Email:
Location: Hornbeam : HNB 1.10
Role: Director of Undergraduate Studies (Pharmaceutical Sciences) in the Keele School of Pharmacy
Contacting me:
Curtis_Tony

I joined Keele as Lecturer in Organic Chemistry in 1993 and was promoted to Senior lecturer in 2004, having previously been a research associate with Prof. T.R. Kelly at Boston College, USA. I obtained my BSc in 1987 from UMIST and went on to obtain a PhD from the University of Manchester in 1990 under the supervision of Prof. R.J. Stoodley. In 2005 I joined the Department of Medicines Management to develop the Keele undergraduate Pharmacy programme and currently hold the post of Director of Undergraduate Studies (Pharmaceutical Science) in the School of Pharmacy, Faculty of Health; please visit the School of Pharmacy web site for further information.

My research interests are varied and include various aspects of the physical and life sciences with a particular focus on the synthesis of molecules with biological or medicinal significance. I am particularly interested in the development of novel photosensitizers for use in photodynamic therapy (PDT) of a variety of pathologies, and also in the synthesis of functional organic molecules for recognition and catalysis. I also undertake research into teaching and learning, in particular the development of task-based group work exercises and studying the impact of individual learning preferences on performance in on-line group work.

Selected Publications

  • Robinson E, Nandi M, Wilkinson L, Arrowsmith M, Curtis ADM, Richardson A. 2013. Preclinical Evaluation of Statins as a Treatment for Ovarian Cancer. Gynecologic Oncology, vol. 129, 417-424. doi>
  • Barnett C, Lees M, Curtis ADM, Kong Thoo Lin P, Cheng WP, Hoskins C. 2013. Poly(allylamine) Magnetomicelles for Image Guided Drug Delivery.
  • Curtis ADM and Jennings N. 2008. 1,2,4-Triazoles. In Comprehensive Heterocyclic Chemistry III: Five-membered rings: Triazoles, Oxadiazoles, Thiadiazoles and their Fused Carbocyclic Derivatives. KATRITZKY AR, RAMSDEN CA, SCRIVEN EFV, TAYLOR RJK (Eds.). (vol. 5.02). Oxford: Elsevier Ltd.
  • Curtis ADM. 2003. 1,2,4-Triazoles. In Science of Synthesis: 5-Membered Hetarenes with Three or More Heteroatoms. BELLUS D, LEY SV, NOYORI R, REGITZ M, REIDER PJ, SCHAUMANN E, SHINKAI I, THOMAS EJ, TROST BM (Eds.). (vol. 13). Stuttgart: Georg Thieme Verlag.
  • Foley S, Curtis ADM, Hirsch A, Brettreich M, Pelegrin A, Seta P, Larroque C. 2002. Interaction of a water soluble fullerene derivative with reactive oxygen species and model enzymatic systems. FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES, vol. 10(1), 49-67. link> doi>

Full Publications List show

Journal Articles

  • Robinson E, Nandi M, Wilkinson L, Arrowsmith M, Curtis ADM, Richardson A. 2013. Preclinical Evaluation of Statins as a Treatment for Ovarian Cancer. Gynecologic Oncology, vol. 129, 417-424. doi>
  • Barnett C, Lees M, Curtis ADM, Kong Thoo Lin P, Cheng WP, Hoskins C. 2013. Poly(allylamine) Magnetomicelles for Image Guided Drug Delivery.
  • Foley S, Curtis ADM, Hirsch A, Brettreich M, Pelegrin A, Seta P, Larroque C. 2002. Interaction of a water soluble fullerene derivative with reactive oxygen species and model enzymatic systems. FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES, vol. 10(1), 49-67. link> doi>
  • Clews J, Curtis ADM, Malkin H. 2001. The synthesis of C-2-symmetric and axially chiral compounds for recognition and catalysis (vol 56, pg 8735, 2000). TETRAHEDRON, vol. 57(28), 6097. link> doi>
  • Clews J, Curtis ADM, Malkin H. 2000. The synthesis of C-2-symmetric and axially chiral compounds for recognition and catalysis. TETRAHEDRON, vol. 56(44), 8735-8746. link> doi>
  • Curtis ADM, Humphries MJ, Ramsden CA. 2000. Studies Directed Towards Conformationally Restricted Nucleosides. ARKIVOC, vol. 1(3), 218-227.
  • Curtis ADM, McCague R, Ramsden CA, Raza RR. 1999. Preparation, characterisation and slow quantitative dissociation of a novel asymmetric N-unsubstituted dialkylsulfimide. CHEMICAL COMMUNICATIONS, 189-190. link> doi>
  • Curtis ADM. 1997. Novel calix[4]resorcinarene glycosides. TETRAHEDRON LETTERS, vol. 38(24), 4295-4296. link> doi>
  • Cousins RPC, Curtis ADM, Ding WC, Stoodley RJ. 1995. 1,5-Asymmetric Inductions in the Reactions of 2-(2',3',4',6'-Tetra-O-acetyl-beta-D-glucopyranosyloxy)benzaldehyde with Danishefsky's Diene. Tetrahedron Letters, vol. 36(47), 8689-8692. doi>
  • Kelly TR, Kim MH, Curtis ADM. 1993. Structure Correction and Synthesis of the Naturally Occurring Benzothiazinone BMY 40662. Journal of Organic Chemistry, vol. 58(21), 5855-5857. doi>
  • Curtis ADM, Mears RJ, Whiting A. 1993. The Origin of the Stereoselectivity in the Aldol Reactions of beta-Boronate Carbonyl Derivatives. Tetrahedron, vol. 49(1), 187-198. doi>
  • Beagley B, Curtis ADM, Pritchard RG, Stoodley RJ. 1992. Asymmetric Diels-Alder Reactions. Part 6. Regio- and Stereo-selective Cycloadditions of 5-(2',3',4',6'-Tetra-O-acetyl-beta-D-glucopyranosyloxy)-1,4-naphthoquinone. Journal of the Chemical Society; Perkin Transactions 1, 1981-1991. doi>
  • Beagley B, Curtis ADM, Pritchard RG, Stoodley RJ. 1991. Highly Regio- and Stereo-selective Diel-Alder Reactions of 5-(2',3',4',6'-Tetra-O-acetyl-beta-D-glucopyranosyloxy)-1,4-naphthoquinone. Chemical Communications, 119-121. doi>
  • Curtis ADM and Whiting A. 1991. Stereoselective Aldol Reactions of beta-Boronate Carbonyl Derivatives. Tetrahedron Letters, vol. 32(11), 1507-1510. doi>

Chapters

  • Curtis ADM and Jennings N. 2008. 1,2,4-Triazoles. In Comprehensive Heterocyclic Chemistry III: Five-membered rings: Triazoles, Oxadiazoles, Thiadiazoles and their Fused Carbocyclic Derivatives. KATRITZKY AR, RAMSDEN CA, SCRIVEN EFV, TAYLOR RJK (Eds.). (vol. 5.02). Oxford: Elsevier Ltd.
  • Curtis ADM. 2003. 1,2,4-Triazoles. In Science of Synthesis: 5-Membered Hetarenes with Three or More Heteroatoms. BELLUS D, LEY SV, NOYORI R, REGITZ M, REIDER PJ, SCHAUMANN E, SHINKAI I, THOMAS EJ, TROST BM (Eds.). (vol. 13). Stuttgart: Georg Thieme Verlag.
  • Curtis ADM. 2000. Carbon-Carbon Bond Formation, Addition, Elimination and Substitution Reactions: 1 Carbon-Carbon Bond Formation Using Enzymes. In Biotechnology: Biotransformations II. (vol. 8b). Stuttgart: VCH Verlag.
  • Curtis ADM. 1996. Bicyclic 5-5 Systems: Four Heteroatoms 1:3. In Comprehensive Heterocyclic Chemistry II: Fused Five and Six-membered Rings without Ring Junction Heteroatoms. KATRITZKY AR, REES CW, SCRIVEN EFV (Eds.). (vol. 7). Oxford: Elsevier Science Ltd.
  • Curtis ADM. 1996. Bicyclic 6-6 Systems: Four Heteroatoms 1:3. In Comprehensive Heterocyclic Chemistry II: Fused Five and Six-membered Rings without Ring Junction Heteroatoms. KATRITZKY AR, REES CW, SCRIVEN EFV (Eds.). (vol. 7). Oxford: Elsevier Science Ltd.
  • CHE-10002 Basic Organic Chemistry
  • CHE-20001 Organic Synthesis and Chirality
  • CHE-20005 Drug Design Based On Biological Targets
  • CHE-30001 Chemical Data Analysis
  • CHE-30002/30030 Chemistry research Projects
  • CHE-30009 Research Topics in Biological and Medicinal Chemistry (Antibiotics and Chemotherapy, Organic Synthesis)
  • LSC-10015 Metabolism: Major Metabolic Pathways
  • LSC-20016 Metabolism in Health and Disease
  • LSC-30018 Biochemistry and Therapy of Disease
  • PHA-10002 Calculations in Pharmacy
  • PHA-10005 MPharm Metabolism: Major Metabolic Pathways
  • PHA-10010 Pharmaceutical Chemistry
  • PHA-10011 Drug Discovery and Use
  • PHA-20002 Pharmaceutical Microbiology
  • PHA-20006 MPharm Metabolism in Health and Disease