Welcome to the research webpages of the Bailey Group. We are an organic and medicinal chemistry
research group based in the EPSAM research institute at Keele University

Two current projects are especially exciting; we're close to completing (we hope!) the synthesis of an indole alkaloid called ajmaline, which is used to treat patients with irregular heartbeat and has 9 adjacent chiral centres in its intricate 3D structure. Secondly, we have been studying how to help the uptake of pharmaceutically important compounds that aren't orally absorbed; we now have a way of attaching such molecules to a special carrier, allowing them to be 'smuggled' into the bloodstream.

Indole alkaloids	PepT1 transporter

Click on the links above to find out more about our research projects.

If you are interested in joining the group we would like to hear from you. Please contact us by e-mail.

We are currently advertising for a PhD position to start summer 2010.

"The design and synthesis of drug carrier molecules
to improve oral bioavailability of pharmaceuticals via the PepT1 transporter"
Reference: EPSAM 2009-04

More details are available from the Keele Graduate School
and the EPSAM Research Institute websites.