PHA-30041 - Advanced Topics in Pharmaceutical Science (Pharmacology)
Coordinator: Alan Richardson Room: HORN 1.08 Tel: +44 1782 7 33571
Lecture Time: See Timetable...
Level: Level 6
Credits: 15
Study Hours: 150
School Office:

Programme/Approved Electives for 2022/23

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

None

Barred Combinations

None

Description for 2022/23

This module will bring together all of the concepts in pharmacology that have been covered in earlier modules to deliver an in-depth examination of topics in pharmacology and related areas, representing current thinking and recent advances in drug therapy with aspects of medicinal chemistry providing appropriate linkages. The application of knowledge gained is key to success in this module. The module will consider pharmacological therapies that are currently used to treat diseases in major body systems. The lectures will cover diseases and therapy associated with the cardiovascular system, the respiratory system, the central nervous system, the gastrointestinal system, the immune system, the renal system hormones, skin, cancer and infection. Students will be encouraged to engage with the primary and secondary literature throughout the module in order to advance skills in research. Students will research the literature describing two therapeutic areas of the their choice.

Aims
This module aims to explain the actions of drugs in the major body systems by providing descriptions of the pathophysiology of common disorders and using defined targets for pharmacological intervention to explain the actions and uses of drugs in therapy. The
therapeutic benefits of drug delivery systems will also be discussed.
This theme is extended beyond currently accepted therapeutic strategies to encourage students to evaluate current research in selected therapeutic areas.

Talis Aspire Reading List
Any reading lists will be provided by the start of the course.
http://lists.lib.keele.ac.uk/modules/pha-30041/lists

Intended Learning Outcomes

demonstrate a systematic understanding of the actions of drugs in terms of their interactions with physiological systems: 1,2
demonstrate a detailed knowledge of the use of drugs to correct disorders of physiological systems
: 1,2
describe and critically evaluate the role of pharmacotherapy in the management of disease
: 1,2
select, with detailed rationale, appropriate drug delivery systems for specific patients to maximise the therapeutic benefits: 1,2
interpret complex data obtained through experiments to formulate conclusions about the actions of drugs in physiological systems: 1
critically evaluate current research and advanced scholarship in pharmaceutical sciences relevant to the chosen research area
: 1
demonstrate an in-depth understanding of analytic and literature evaluation techniques
: 1
critically appraise published clinical and experimental data using a structured approach, in order to assess its quality and validity.: 1
demonstrate detailed knowledge of the physicochemical properties of advanced and cutting-edge drug delivery
systems
: 1,2

Study hours

Large- and small-group teaching sessions: 20 hours
Skills-based laboratory and practical skills activity: 10 hours
Directed private study, revision and assessment: 118 hours
Examinations: 2 hours

School Rules

None

Description of Module Assessment

1: Coursework weighted 60%
Coursework
(a) Research Reports (30% of module marks) A series of two, 500 word reports that explore therapeutic areas to be submitted over a sequence of weeks, ideally one in each semester and associated with relevant teaching content, each of which will receive formative feedback. The final submission (1000-1100 words) will be a document comprising both separate reports (revised following to feedback) combined with a final reflective paragraph on the learning process. (b) Laboratory report (30% of module mark) One laboratory report in pharmacology or a related area

2: Exam weighted 40%
End of module examination
The end of module examination will comprise one papers (2 hours) and will contain written answer questions (LAQs). This examination may contain seen components, and the examination will be online.