|
Neuroscience |
Neuroscience is the study of the most intricate control system in the body: the nervous system. Our nervous system gives us the ability to sense the environment and to react to it. Ultimately all human behaviour, whether conscious or unconscious, stems from the processes occurring in the complicated networks of nerve cells that form our brain and spinal cord.
The Neuroscience course at Keele is designed to equip you with a broadly based understanding of the principles of neuroscience and is taught by tutors who are all active researchers. You will learn about the structure and function of the nervous system, the action of drugs, and the molecular biology of neurological diseases or disorders.
NB. Because of variations in staff availability and research interests from time to time, certain modules
may not run in particular semesters. Erasmus, Exchange and Study Abroad students please confirm
module availability with the School when applying.
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| LSC-10029 | Introduction to Neuroscience | C | M | 7.5 | 15 | |
| This module teaches students about the basic anatomy and function of the nervous system, drawing on information from a range of organisms but primarily aimed at understanding the human nervous system. Included in this module are practical classes that introduce students to human and animal anatomy and physiology, microscopy and recording techniques using computer based physiology work stations. Students also experiment on the main senses using anatomical, physiological and behavioural methods and learn a range of other skills useful in a variety of different jobs. | ||||||
| LSC-10031 | Cell and Molecular Biology | C | M | 7.5 | 15 | |
| The module will examine the fundamental importance of cell and molecular biology in relation to complex living organisms. After a general exploration of cell structure, organelles, membranes and intermediary metabolism, the module concentrates on cell division by exploring the cell cycle, chromosome structure, mitosis and meiosis. Subsequently, the module tackles the concepts of DNA structure, replication, mutation and repair, leading to a description of how genes are expressed and regulated. The impact of man on genetics and cell biology is explored through a consideration of recombinant DNA technology and genomics. Finally, the module provides an introduction to the genetic basis of development. The associated practicals give a wide-ranging coverage of modern molecular techniques with which all biologists need to be familiar and provide opportunities to gain skills in information retrieval and oral presentation. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| LSC-10032 | Genetics and Evolution | C | M | 7.5 | 15 | |
| The module will examine the fundamental roles of genetics and evolution through a combination of classical and molecular studies. Concepts of Mendelian inheritance patterns will be introduced and reasons for divergence from these classical patterns described. The importance of genetic variability will be stressed in relation to living organisms both at the individual and population level. The module will raise awareness of the evolutionary process and discuss concepts of speciation and phylogeny, with a focus on human evolution. During practical classes and tutorials, the module will allow students to gain experience in the conduct, analysis and interpretation of genetic investigations. The module also provides an opportunity to address fundamental issues in bioethics with a focus on animal experimentation. | ||||||
| LSC-10039 | Human physiology and pathology | C | M | 7.5 | 15 | |
| This module provides a basic background to the physiological systems of the human body and the pathological changes that occur during relevant diseases. The systems covered are the cardiovascular, immune, respiratory, urinary and endocrine / reproductive systems. The module is taught using both lectures and practical classes. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| + | LSC-20023 | Development and Evolution of Nervous Systems | C | M | 7.5 | 15 |
| This module teaches you about how evolutionary processes have shaped the nervous system, from simple invertebrates that possess a basic neural network, like a sea anemone, to vertebrates with their highly centralised nervous system. We take a tour of the different animal groups and piece together possible routes of evolution of the nervous system from the more primitive through to the more advanced living groups; how intelligence appears to have evolved like other traits using evidence from the fossil record. Moving to the present day, we then describe how the body builds its nervous system using anatomical, physiological and molecular biological data; we try to answer questions about how neurones grow, how synapses are made and pruned and how wiring develops with particular reference to vertebrate nervous systems. The module ends with a discussion of repair and regeneration (or lack of them!) in the nervous system and possible ways to enhance nervous system repair mechanisms in the future. | ||||||
| + | LSC-20027 | From Neurone to Brain | C | M | 7.5 | 15 |
| This module builds on the material presented during Level 1 (LSC- 10029 - Introduction to Neuroscience) and provides a general outline of structure and function of individual neurons and their populations together with the techniques used to investigate them. During the lectures, practicals, seminars, tutorials and comprehension paper exercise we: 1.Describe the main features of gross brain anatomy and the locations and main functions of the cranial nerves. 2. Demonstrate the neuronal specialisations that enable signalling between neurones, and explain how neurones integrate excitatory and inhibitory inputs. 3. Summarise how synaptic function can be altered by experience and the underlying molecular changes involved. 4. Demonstrate using examples how networks of neurones function and the role of these networks in modulating or supporting brain function. Examples of neuronal networks to be covered are the basal ganglia, and the somatosensory and chemosensory systems of mammals, noting that these may change. | ||||||
| LSC-20029 | Neuroscience - Study Abroad I | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20030 | Neuroscience - Study Abroad II | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| + | LSC-20031 | Human and Animal Cognition | C | M | 7.5 | 15 |
| This module compares the mental abilities of animals and humans by studying selected aspects of their behaviour that might be considered "intelligent". We consider the extent to which animals' learning is constrained by their genetic background and then go on to examine the evidence that some animals can form mental images. A major topic is how animals find their way, and we introduce the concept of the cognitive map - a neural representation of the spatial relationships of places familiar to animals. Whether they use this or other methods in their home range and in navigating during their large scale (global) migrations is studied. The ability to solve problems and use tools, and pass on these skills to others in the group is followed by discussion of whether animals may have any concept of self. The final animal topic is communication and language which leads nicely into two aspects of human cognition: language and consciousness. Both are considered from a neurobiological viewpoint: from classic views to present day. The role of functional brain scanning techniques coupled with relevant pathological states is discussed. | ||||||
| LSC-20038 | Neuroscience - Study Abroad III | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20039 | Neuroscience - Study Abroad IV | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20056 | Research and Analytical Skills | C | M | 7.5 | 15 | |
| This module looks at the skills and techniques used by scientists to collect, analyse and present scientific information to a specialist and wider audience. It includes specific skills such as writing, experimental design, data analysis and presentation within an ethical framework. In addition these skills will be invaluable for 3rd year projects and dissertations. Indicative content: - Analysis of the structure and content of scientific papers, with particular reference to the design and analysis of scientific experiments within an ethical dimension. - How data is arranged (tables, graphs, figures), presented using Word, Excel and PowerPoint, summarized (summary statistics) and compared. - Searching for scientific information on the internet, electronic databases, libraries and its collation and oral presentation in a seminar. - Statistical analysis of the data is a major component of the module with in-depth study of the most commonly used statistical analyses, including: T-test, ANOVA, regression, correlation, non-parametric tests, categorical data, linearity, cross-reactivity, sensitivity, specificity, accuracy and precision. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| + | LSC-30001 | Behavioural Neurobiology | O | M | 7.5 | 15 |
| This is a multidisciplinary module whose aim is to develop an understanding of animal (including human) behaviour in terms of the function of the nervous system. This module concentrates on the brains of mammals, especially humans, and on sub-cortical systems. There are occasional references to lower vertebrates and even invertebrates where the study of shared mechanisms in simpler animals is useful. Modern neuroscience is an interdisciplinary study, and this is reflected in the syllabus in that it draws on information from anatomy and microanatomy, physiology, neurochemistry, neuropharmacology and neuroendocrinology to bring about an understanding of behaviour. Lectures are supported by a series of student-led seminars based on recent research publications. Topics covered include pleasure and pain, fear, stress and sleep all linked through the pervading theme of learning and memory. There are no pre-requisites, but students who have done little or no neuroscience before are likely to find it difficult and would be well advised to read Part 1 of the main recommended text, Bear Connors and Paradiso: Neuroscience: Exploring the Brain (Lippincott Williams and Wilkins, 3rd edition 2007) before taking the module. | ||||||
| # | LSC-30019 | Applied Life Sciences Placement - ISP | O | C | 7.5 | 15 |
| Issues in the biological sciences are an area of growing importance in all sectors of work and professional development. Students on this module will gain experience of applying understanding of practical techniques within a professional business, and/or research environment. Students will be supported in developing effective professional/research practices through training in leadership and project management. They will also develop independent reflective learning practices to enhance their continuing professional development. The practical work carried out during the period of employment prior to the beginning of the student's final year will take the place of the experimental project. During the first semester of the final year the student will write a report on this practical work which will be submitted before the end of the Autumn Term. | ||||||
| + | LSC-30020 | Neurobiological Basis of Brain Disease | O | M | 7.5 | 15 |
| The lectures in this module will review the occurrence, cause, aetiology and neuropathology of a number of common neurodegenerative diseases and neurobiological conditions. The lecture material will be complemented by a number of Clinical Presentations which will stress the clinical aspects of neurodegenerative disease. | ||||||
| Semester 1-2 | C/O | TYP | ECTS | CATS | ||
| # | LSC-30021 | Final Year Project for Neuroscience - ISP | O | C | 7.5 | 15 |
| This module introduces students to the concept, philosophy and approach to performing scientific research by enabling them to conduct a substantial laboratory project as an individual initiative, and presenting it in a scholarly fashion. | ||||||
| # | LSC-30022 | Non-experimental Project - ISP | O | C | 7.5 | 15 |
| This module introduces students to the concept, philosophy and approach to performing scientific research by enabling you to conduct a substantial non-experimental project as an individual initiative, and presenting it in a scholarly fashion. | ||||||
| # | LSC-30023 | Dissertation - ISP | O | C | 7.5 | 15 |
| The aims of this module are to introduce students to the concept, philosophy and approach to performing scientific research by conducting an extensive literature survey as an individual initiative, and presenting it in a scholarly fashion. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| + | LSC-30005 | Neurobiology of Vision and Hearing | O | M | 7.5 | 15 |
| Vision and hearing are arguably the two most important human senses. In this module, we will examine the neuroanatomy and neurophysiology of vertebrate visual and auditory systems, from sensory transduction in the retina and cochlea to cortical processing and integration of sensory information within specific brain regions. The module is taught as a series of lectures linked with interactive tutorials. The tutors have active research programmes in this area of neuroscience, and recent relevant research papers are discussed during the module. Assessment is via a scientific paper comprehension test and end of module exam. | ||||||
| LSC-30039 | Regeneration and Repair in the Nervous System | O | M | 7.5 | 15 | |
| The adult nervous system displays quite a remarkable ability to regenerate following degeneration, or trauma. Furthermore, is has been extensively demonstrated that primary neuronal tissue/cells, can be transplanted into the adult nervous system, and given an appropriate time period, can integrate with the host tissue, ultimately restoring neurological function. In this module, we will explore regeneration and repair strategies across the peripheral, and central (Brain and spinal cord) nervous systems, and examine their application in an array of neurological disorders, including; Parkinson's disease, Huntington's disease, spinal cord trauma, multiple sclerosis, and stroke. The module is taught via a series of lectures,and the tutors on this module are drawn from researchers with an active programme in nervous system regeneration and repair. Assessment is via an end of module exam, a grant proposal, and peer-review of grant proposals. | ||||||
| LSC-30042 | Current Research Topics in Neuroscience | O | M | 7.5 | 15 | |
| Neuroscience is one of the fastest growing research areas with new concepts and ideas emerging all the time. Keeping track of these new areas is a challenging but rewarding task for the neuroscientist, especially those interested in deep knowledge of their subject and potentially interested in a research career. In this module you will learn about the most recent advances in neuroscience and their implications. You will be expected to read journal articles on a specific topic and learn how to summarize and evaluate the subject area concisely, in the process developing a better understand of the subject and an ability to identify the key points and what they mean for the future of neuroscience. Assessment will be on a portfolio of summaries of selected research topics (you will be able to choose your four best out of seven for assessment) and an exam that will ask questions that test your evidence-based knowledge of the subjects. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| LSC-10029 | Introduction to Neuroscience | C | M | 7.5 | 15 | |
| This module teaches students about the basic anatomy and function of the nervous system, drawing on information from a range of organisms but primarily aimed at understanding the human nervous system. Included in this module are practical classes that introduce students to human and animal anatomy and physiology, microscopy and recording techniques using computer based physiology work stations. Students also experiment on the main senses using anatomical, physiological and behavioural methods and learn a range of other skills useful in a variety of different jobs. | ||||||
| LSC-10031 | Cell and Molecular Biology | C | M | 7.5 | 15 | |
| The module will examine the fundamental importance of cell and molecular biology in relation to complex living organisms. After a general exploration of cell structure, organelles, membranes and intermediary metabolism, the module concentrates on cell division by exploring the cell cycle, chromosome structure, mitosis and meiosis. Subsequently, the module tackles the concepts of DNA structure, replication, mutation and repair, leading to a description of how genes are expressed and regulated. The impact of man on genetics and cell biology is explored through a consideration of recombinant DNA technology and genomics. Finally, the module provides an introduction to the genetic basis of development. The associated practicals give a wide-ranging coverage of modern molecular techniques with which all biologists need to be familiar and provide opportunities to gain skills in information retrieval and oral presentation. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| LSC-10032 | Genetics and Evolution | C | M | 7.5 | 15 | |
| The module will examine the fundamental roles of genetics and evolution through a combination of classical and molecular studies. Concepts of Mendelian inheritance patterns will be introduced and reasons for divergence from these classical patterns described. The importance of genetic variability will be stressed in relation to living organisms both at the individual and population level. The module will raise awareness of the evolutionary process and discuss concepts of speciation and phylogeny, with a focus on human evolution. During practical classes and tutorials, the module will allow students to gain experience in the conduct, analysis and interpretation of genetic investigations. The module also provides an opportunity to address fundamental issues in bioethics with a focus on animal experimentation. | ||||||
| LSC-10039 | Human physiology and pathology | C | M | 7.5 | 15 | |
| This module provides a basic background to the physiological systems of the human body and the pathological changes that occur during relevant diseases. The systems covered are the cardiovascular, immune, respiratory, urinary and endocrine / reproductive systems. The module is taught using both lectures and practical classes. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| + | LSC-20023 | Development and Evolution of Nervous Systems | C | M | 7.5 | 15 |
| This module teaches you about how evolutionary processes have shaped the nervous system, from simple invertebrates that possess a basic neural network, like a sea anemone, to vertebrates with their highly centralised nervous system. We take a tour of the different animal groups and piece together possible routes of evolution of the nervous system from the more primitive through to the more advanced living groups; how intelligence appears to have evolved like other traits using evidence from the fossil record. Moving to the present day, we then describe how the body builds its nervous system using anatomical, physiological and molecular biological data; we try to answer questions about how neurones grow, how synapses are made and pruned and how wiring develops with particular reference to vertebrate nervous systems. The module ends with a discussion of repair and regeneration (or lack of them!) in the nervous system and possible ways to enhance nervous system repair mechanisms in the future. | ||||||
| + | LSC-20027 | From Neurone to Brain | C | M | 7.5 | 15 |
| This module builds on the material presented during Level 1 (LSC- 10029 - Introduction to Neuroscience) and provides a general outline of structure and function of individual neurons and their populations together with the techniques used to investigate them. During the lectures, practicals, seminars, tutorials and comprehension paper exercise we: 1.Describe the main features of gross brain anatomy and the locations and main functions of the cranial nerves. 2. Demonstrate the neuronal specialisations that enable signalling between neurones, and explain how neurones integrate excitatory and inhibitory inputs. 3. Summarise how synaptic function can be altered by experience and the underlying molecular changes involved. 4. Demonstrate using examples how networks of neurones function and the role of these networks in modulating or supporting brain function. Examples of neuronal networks to be covered are the basal ganglia, and the somatosensory and chemosensory systems of mammals, noting that these may change. | ||||||
| LSC-20029 | Neuroscience - Study Abroad I | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20030 | Neuroscience - Study Abroad II | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| + | LSC-20031 | Human and Animal Cognition | C | M | 7.5 | 15 |
| This module compares the mental abilities of animals and humans by studying selected aspects of their behaviour that might be considered "intelligent". We consider the extent to which animals' learning is constrained by their genetic background and then go on to examine the evidence that some animals can form mental images. A major topic is how animals find their way, and we introduce the concept of the cognitive map - a neural representation of the spatial relationships of places familiar to animals. Whether they use this or other methods in their home range and in navigating during their large scale (global) migrations is studied. The ability to solve problems and use tools, and pass on these skills to others in the group is followed by discussion of whether animals may have any concept of self. The final animal topic is communication and language which leads nicely into two aspects of human cognition: language and consciousness. Both are considered from a neurobiological viewpoint: from classic views to present day. The role of functional brain scanning techniques coupled with relevant pathological states is discussed. | ||||||
| LSC-20038 | Neuroscience - Study Abroad III | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20039 | Neuroscience - Study Abroad IV | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20056 | Research and Analytical Skills | C | M | 7.5 | 15 | |
| This module looks at the skills and techniques used by scientists to collect, analyse and present scientific information to a specialist and wider audience. It includes specific skills such as writing, experimental design, data analysis and presentation within an ethical framework. In addition these skills will be invaluable for 3rd year projects and dissertations. Indicative content: - Analysis of the structure and content of scientific papers, with particular reference to the design and analysis of scientific experiments within an ethical dimension. - How data is arranged (tables, graphs, figures), presented using Word, Excel and PowerPoint, summarized (summary statistics) and compared. - Searching for scientific information on the internet, electronic databases, libraries and its collation and oral presentation in a seminar. - Statistical analysis of the data is a major component of the module with in-depth study of the most commonly used statistical analyses, including: T-test, ANOVA, regression, correlation, non-parametric tests, categorical data, linearity, cross-reactivity, sensitivity, specificity, accuracy and precision. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| + | LSC-30001 | Behavioural Neurobiology | C | M | 7.5 | 15 |
| This is a multidisciplinary module whose aim is to develop an understanding of animal (including human) behaviour in terms of the function of the nervous system. This module concentrates on the brains of mammals, especially humans, and on sub-cortical systems. There are occasional references to lower vertebrates and even invertebrates where the study of shared mechanisms in simpler animals is useful. Modern neuroscience is an interdisciplinary study, and this is reflected in the syllabus in that it draws on information from anatomy and microanatomy, physiology, neurochemistry, neuropharmacology and neuroendocrinology to bring about an understanding of behaviour. Lectures are supported by a series of student-led seminars based on recent research publications. Topics covered include pleasure and pain, fear, stress and sleep all linked through the pervading theme of learning and memory. There are no pre-requisites, but students who have done little or no neuroscience before are likely to find it difficult and would be well advised to read Part 1 of the main recommended text, Bear Connors and Paradiso: Neuroscience: Exploring the Brain (Lippincott Williams and Wilkins, 3rd edition 2007) before taking the module. | ||||||
| # | LSC-30019 | Applied Life Sciences Placement - ISP | O | C | 7.5 | 15 |
| Issues in the biological sciences are an area of growing importance in all sectors of work and professional development. Students on this module will gain experience of applying understanding of practical techniques within a professional business, and/or research environment. Students will be supported in developing effective professional/research practices through training in leadership and project management. They will also develop independent reflective learning practices to enhance their continuing professional development. The practical work carried out during the period of employment prior to the beginning of the student's final year will take the place of the experimental project. During the first semester of the final year the student will write a report on this practical work which will be submitted before the end of the Autumn Term. | ||||||
| + | LSC-30020 | Neurobiological Basis of Brain Disease | C | M | 7.5 | 15 |
| The lectures in this module will review the occurrence, cause, aetiology and neuropathology of a number of common neurodegenerative diseases and neurobiological conditions. The lecture material will be complemented by a number of Clinical Presentations which will stress the clinical aspects of neurodegenerative disease. | ||||||
| LSC-30038 | Double Applied Life Sciences Placement - ISP | O | C | 15 | 30 | |
| A double placement research project is an opportunity for students to carry out a substantial piece of meaningful research at a host industrial, governmental or academic partner either within the UK or another European State. Students will get a taste of what it is like to work in a real research environment and obtain substantial employment skills whilst on placement and during their report preparation. Students will work independently on a research project under the supervision of a member of academic staff from the School of Life Sciences and the host partner. Research topics are offered in a range of subject areas and incorporate training in generic and specialised scientific skills. | ||||||
| Semester 1-2 | C/O | TYP | ECTS | CATS | ||
| # | LSC-30021 | Final Year Project for Neuroscience - ISP | O | C | 7.5 | 15 |
| This module introduces students to the concept, philosophy and approach to performing scientific research by enabling them to conduct a substantial laboratory project as an individual initiative, and presenting it in a scholarly fashion. | ||||||
| # | LSC-30023 | Dissertation - ISP | O | C | 7.5 | 15 |
| The aims of this module are to introduce students to the concept, philosophy and approach to performing scientific research by conducting an extensive literature survey as an individual initiative, and presenting it in a scholarly fashion. | ||||||
| LSC-30040 | Double Neuroscience Research Project - ISP | O | C | 15 | 30 | |
| Students will carry out their research project under the supervision of a member of academic or research staff. Students will collect data during 10 weeks in semester 1 (approx 2 days/week) before the end of the year. They will be involved in the planning and execution of experiments, using some laboratory techniques that they have not previously used during the laboratory classes in years 1 and 2. Students will process, present and interpret their results in a substantial written report in semester 2. They will also record their progress in a lab book on a daily basis. The project report should be communicated at a level suitable for publication in the primary literature | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| + | LSC-30005 | Neurobiology of Vision and Hearing | C | M | 7.5 | 15 |
| Vision and hearing are arguably the two most important human senses. In this module, we will examine the neuroanatomy and neurophysiology of vertebrate visual and auditory systems, from sensory transduction in the retina and cochlea to cortical processing and integration of sensory information within specific brain regions. The module is taught as a series of lectures linked with interactive tutorials. The tutors have active research programmes in this area of neuroscience, and recent relevant research papers are discussed during the module. Assessment is via a scientific paper comprehension test and end of module exam. | ||||||
| LSC-30039 | Regeneration and Repair in the Nervous System | C | M | 7.5 | 15 | |
| The adult nervous system displays quite a remarkable ability to regenerate following degeneration, or trauma. Furthermore, is has been extensively demonstrated that primary neuronal tissue/cells, can be transplanted into the adult nervous system, and given an appropriate time period, can integrate with the host tissue, ultimately restoring neurological function. In this module, we will explore regeneration and repair strategies across the peripheral, and central (Brain and spinal cord) nervous systems, and examine their application in an array of neurological disorders, including; Parkinson's disease, Huntington's disease, spinal cord trauma, multiple sclerosis, and stroke. The module is taught via a series of lectures,and the tutors on this module are drawn from researchers with an active programme in nervous system regeneration and repair. Assessment is via an end of module exam, a grant proposal, and peer-review of grant proposals. | ||||||
| LSC-30042 | Current Research Topics in Neuroscience | C | M | 7.5 | 15 | |
| Neuroscience is one of the fastest growing research areas with new concepts and ideas emerging all the time. Keeping track of these new areas is a challenging but rewarding task for the neuroscientist, especially those interested in deep knowledge of their subject and potentially interested in a research career. In this module you will learn about the most recent advances in neuroscience and their implications. You will be expected to read journal articles on a specific topic and learn how to summarize and evaluate the subject area concisely, in the process developing a better understand of the subject and an ability to identify the key points and what they mean for the future of neuroscience. Assessment will be on a portfolio of summaries of selected research topics (you will be able to choose your four best out of seven for assessment) and an exam that will ask questions that test your evidence-based knowledge of the subjects. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| LSC-10029 | Introduction to Neuroscience | C | M | 7.5 | 15 | |
| This module teaches students about the basic anatomy and function of the nervous system, drawing on information from a range of organisms but primarily aimed at understanding the human nervous system. Included in this module are practical classes that introduce students to human and animal anatomy and physiology, microscopy and recording techniques using computer based physiology work stations. Students also experiment on the main senses using anatomical, physiological and behavioural methods and learn a range of other skills useful in a variety of different jobs. | ||||||
| LSC-10031 | Cell and Molecular Biology | C | M | 7.5 | 15 | |
| The module will examine the fundamental importance of cell and molecular biology in relation to complex living organisms. After a general exploration of cell structure, organelles, membranes and intermediary metabolism, the module concentrates on cell division by exploring the cell cycle, chromosome structure, mitosis and meiosis. Subsequently, the module tackles the concepts of DNA structure, replication, mutation and repair, leading to a description of how genes are expressed and regulated. The impact of man on genetics and cell biology is explored through a consideration of recombinant DNA technology and genomics. Finally, the module provides an introduction to the genetic basis of development. The associated practicals give a wide-ranging coverage of modern molecular techniques with which all biologists need to be familiar and provide opportunities to gain skills in information retrieval and oral presentation. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| LSC-10032 | Genetics and Evolution | C | M | 7.5 | 15 | |
| The module will examine the fundamental roles of genetics and evolution through a combination of classical and molecular studies. Concepts of Mendelian inheritance patterns will be introduced and reasons for divergence from these classical patterns described. The importance of genetic variability will be stressed in relation to living organisms both at the individual and population level. The module will raise awareness of the evolutionary process and discuss concepts of speciation and phylogeny, with a focus on human evolution. During practical classes and tutorials, the module will allow students to gain experience in the conduct, analysis and interpretation of genetic investigations. The module also provides an opportunity to address fundamental issues in bioethics with a focus on animal experimentation. | ||||||
| LSC-10039 | Human physiology and pathology | C | M | 7.5 | 15 | |
| This module provides a basic background to the physiological systems of the human body and the pathological changes that occur during relevant diseases. The systems covered are the cardiovascular, immune, respiratory, urinary and endocrine / reproductive systems. The module is taught using both lectures and practical classes. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| + | LSC-20023 | Development and Evolution of Nervous Systems | C | M | 7.5 | 15 |
| This module teaches you about how evolutionary processes have shaped the nervous system, from simple invertebrates that possess a basic neural network, like a sea anemone, to vertebrates with their highly centralised nervous system. We take a tour of the different animal groups and piece together possible routes of evolution of the nervous system from the more primitive through to the more advanced living groups; how intelligence appears to have evolved like other traits using evidence from the fossil record. Moving to the present day, we then describe how the body builds its nervous system using anatomical, physiological and molecular biological data; we try to answer questions about how neurones grow, how synapses are made and pruned and how wiring develops with particular reference to vertebrate nervous systems. The module ends with a discussion of repair and regeneration (or lack of them!) in the nervous system and possible ways to enhance nervous system repair mechanisms in the future. | ||||||
| + | LSC-20027 | From Neurone to Brain | C | M | 7.5 | 15 |
| This module builds on the material presented during Level 1 (LSC- 10029 - Introduction to Neuroscience) and provides a general outline of structure and function of individual neurons and their populations together with the techniques used to investigate them. During the lectures, practicals, seminars, tutorials and comprehension paper exercise we: 1.Describe the main features of gross brain anatomy and the locations and main functions of the cranial nerves. 2. Demonstrate the neuronal specialisations that enable signalling between neurones, and explain how neurones integrate excitatory and inhibitory inputs. 3. Summarise how synaptic function can be altered by experience and the underlying molecular changes involved. 4. Demonstrate using examples how networks of neurones function and the role of these networks in modulating or supporting brain function. Examples of neuronal networks to be covered are the basal ganglia, and the somatosensory and chemosensory systems of mammals, noting that these may change. | ||||||
| LSC-20029 | Neuroscience - Study Abroad I | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20030 | Neuroscience - Study Abroad II | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| + | LSC-20031 | Human and Animal Cognition | C | M | 7.5 | 15 |
| This module compares the mental abilities of animals and humans by studying selected aspects of their behaviour that might be considered "intelligent". We consider the extent to which animals' learning is constrained by their genetic background and then go on to examine the evidence that some animals can form mental images. A major topic is how animals find their way, and we introduce the concept of the cognitive map - a neural representation of the spatial relationships of places familiar to animals. Whether they use this or other methods in their home range and in navigating during their large scale (global) migrations is studied. The ability to solve problems and use tools, and pass on these skills to others in the group is followed by discussion of whether animals may have any concept of self. The final animal topic is communication and language which leads nicely into two aspects of human cognition: language and consciousness. Both are considered from a neurobiological viewpoint: from classic views to present day. The role of functional brain scanning techniques coupled with relevant pathological states is discussed. | ||||||
| LSC-20038 | Neuroscience - Study Abroad III | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20039 | Neuroscience - Study Abroad IV | EP | C | 7.5 | 15 | |
| This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. | ||||||
| LSC-20056 | Research and Analytical Skills | C | M | 7.5 | 15 | |
| This module looks at the skills and techniques used by scientists to collect, analyse and present scientific information to a specialist and wider audience. It includes specific skills such as writing, experimental design, data analysis and presentation within an ethical framework. In addition these skills will be invaluable for 3rd year projects and dissertations. Indicative content: - Analysis of the structure and content of scientific papers, with particular reference to the design and analysis of scientific experiments within an ethical dimension. - How data is arranged (tables, graphs, figures), presented using Word, Excel and PowerPoint, summarized (summary statistics) and compared. - Searching for scientific information on the internet, electronic databases, libraries and its collation and oral presentation in a seminar. - Statistical analysis of the data is a major component of the module with in-depth study of the most commonly used statistical analyses, including: T-test, ANOVA, regression, correlation, non-parametric tests, categorical data, linearity, cross-reactivity, sensitivity, specificity, accuracy and precision. | ||||||
| Semester 1 | C/O | TYP | ECTS | CATS | ||
| + | LSC-30001 | Behavioural Neurobiology | EP | M | 7.5 | 15 |
| This is a multidisciplinary module whose aim is to develop an understanding of animal (including human) behaviour in terms of the function of the nervous system. This module concentrates on the brains of mammals, especially humans, and on sub-cortical systems. There are occasional references to lower vertebrates and even invertebrates where the study of shared mechanisms in simpler animals is useful. Modern neuroscience is an interdisciplinary study, and this is reflected in the syllabus in that it draws on information from anatomy and microanatomy, physiology, neurochemistry, neuropharmacology and neuroendocrinology to bring about an understanding of behaviour. Lectures are supported by a series of student-led seminars based on recent research publications. Topics covered include pleasure and pain, fear, stress and sleep all linked through the pervading theme of learning and memory. There are no pre-requisites, but students who have done little or no neuroscience before are likely to find it difficult and would be well advised to read Part 1 of the main recommended text, Bear Connors and Paradiso: Neuroscience: Exploring the Brain (Lippincott Williams and Wilkins, 3rd edition 2007) before taking the module. | ||||||
| + | LSC-30020 | Neurobiological Basis of Brain Disease | EP | M | 7.5 | 15 |
| The lectures in this module will review the occurrence, cause, aetiology and neuropathology of a number of common neurodegenerative diseases and neurobiological conditions. The lecture material will be complemented by a number of Clinical Presentations which will stress the clinical aspects of neurodegenerative disease. | ||||||
| Semester 2 | C/O | TYP | ECTS | CATS | ||
| + | LSC-30005 | Neurobiology of Vision and Hearing | EP | M | 7.5 | 15 |
| Vision and hearing are arguably the two most important human senses. In this module, we will examine the neuroanatomy and neurophysiology of vertebrate visual and auditory systems, from sensory transduction in the retina and cochlea to cortical processing and integration of sensory information within specific brain regions. The module is taught as a series of lectures linked with interactive tutorials. The tutors have active research programmes in this area of neuroscience, and recent relevant research papers are discussed during the module. Assessment is via a scientific paper comprehension test and end of module exam. | ||||||
| LSC-30039 | Regeneration and Repair in the Nervous System | EP | M | 7.5 | 15 | |
| The adult nervous system displays quite a remarkable ability to regenerate following degeneration, or trauma. Furthermore, is has been extensively demonstrated that primary neuronal tissue/cells, can be transplanted into the adult nervous system, and given an appropriate time period, can integrate with the host tissue, ultimately restoring neurological function. In this module, we will explore regeneration and repair strategies across the peripheral, and central (Brain and spinal cord) nervous systems, and examine their application in an array of neurological disorders, including; Parkinson's disease, Huntington's disease, spinal cord trauma, multiple sclerosis, and stroke. The module is taught via a series of lectures,and the tutors on this module are drawn from researchers with an active programme in nervous system regeneration and repair. Assessment is via an end of module exam, a grant proposal, and peer-review of grant proposals. | ||||||
| LSC-30042 | Current Research Topics in Neuroscience | EP | M | 7.5 | 15 | |
| Neuroscience is one of the fastest growing research areas with new concepts and ideas emerging all the time. Keeping track of these new areas is a challenging but rewarding task for the neuroscientist, especially those interested in deep knowledge of their subject and potentially interested in a research career. In this module you will learn about the most recent advances in neuroscience and their implications. You will be expected to read journal articles on a specific topic and learn how to summarize and evaluate the subject area concisely, in the process developing a better understand of the subject and an ability to identify the key points and what they mean for the future of neuroscience. Assessment will be on a portfolio of summaries of selected research topics (you will be able to choose your four best out of seven for assessment) and an exam that will ask questions that test your evidence-based knowledge of the subjects. | ||||||