| Semester 2 |
C/O |
TYP |
ECTS | CATS |
|
~
|
LSC-20005 |
Endocrinology and Cell Signalling |
C |
M
|
7.5 |
15 |
|
|
This module will explore some of the ways in which cells transmit, receive and interpret signals. You will consider how information is encoded, secreted and transmitted to target cells and how incoming signals are recognised and transduced into meaningful information, to elicit the appropriate responses of target cells to signals. Specific details of a number of mammalian cell signalling pathways are used to illustrate principles and concepts and may include G-protein coupled receptor signalling, examples of second messengers, such as the inositol phosphates, insulin signalling as an example of receptor tyrosine kinase signalling and the regulation of gene transcription in mediating the actions of lipophilic hormones.
|
|
+
|
LSC-20016 |
Metabolism in Health and Disease |
C |
M
|
7.5 |
15 |
|
|
This module will describe and explain the specialisation and
interdependence of metabolism within the bodies of mammals and of
man: homeostasis; adaptation to nutritional state; elimination of
drugs and harmful substances and will explore the issues
surrounding the changes in metabolism associated with inherited
and acquired disease.
|
|
|
LSC-20036 |
Biochemistry - Study Abroad III |
EP |
C
|
7.5 |
15 |
|
|
This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. |
|
|
LSC-20037 |
Biochemistry - Study Abroad IV |
EP |
C
|
7.5 |
15 |
|
|
This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. |
| Semester 1 |
C/O |
TYP |
ECTS | CATS |
|
#
|
LSC-30016 |
Structural Biology & Macromolecular Function |
O |
M
|
7.5 |
15 |
|
|
Advances in biotechnology, biology and biomedicine, and their impact on the quality of life, the economy, medicine and health care increasingly depend on the application of structural biology which provides detailed three-dimensional structural information at the atomic level of the proteins which are central to all life processes. While structural biology includes a variety of different techniques such as crystallography and electron microscopy, this module concentrates on the outcomes of these techniques rather than the techniques themselves, with in-depth analysis of how proteins, enzymes and viruses recognise and bind their targets, and how detailed structural information is used to intervene in or enhance these processes. An important aspect of health and well being in all forms of life is the ability to prevent, resist, fight and recover from infection and disease, and much of the course concentrates on how an increased understanding of the molecular mechanisms involved provides a unique opportunity for the design of potential diagnostic and therapeutic agents and strategies. |
|
#
|
LSC-30016 |
Structural Biology & Macromolecular Function |
EP |
M
|
7.5 |
15 |
|
|
Advances in biotechnology, biology and biomedicine, and their impact on the quality of life, the economy, medicine and health care increasingly depend on the application of structural biology which provides detailed three-dimensional structural information at the atomic level of the proteins which are central to all life processes. While structural biology includes a variety of different techniques such as crystallography and electron microscopy, this module concentrates on the outcomes of these techniques rather than the techniques themselves, with in-depth analysis of how proteins, enzymes and viruses recognise and bind their targets, and how detailed structural information is used to intervene in or enhance these processes. An important aspect of health and well being in all forms of life is the ability to prevent, resist, fight and recover from infection and disease, and much of the course concentrates on how an increased understanding of the molecular mechanisms involved provides a unique opportunity for the design of potential diagnostic and therapeutic agents and strategies. |
|
#
|
LSC-30019 |
Applied Life Sciences Placement - ISP |
O |
C
|
7.5 |
15 |
|
|
Issues in the biological sciences are an area of growing importance in all sectors of work and professional development. Students on this module will gain experience of applying understanding of practical techniques within a professional business, and/or research environment. Students will be supported in developing effective professional/research practices through training in leadership and project management. They will also develop independent reflective learning practices to enhance their continuing professional development. The practical work carried out during the period of employment prior to the beginning of the student's final year will take the place of the experimental project. During the first semester of the final year the student will write a report on this practical work which will be submitted before the end of the Autumn Term. |
|
#
|
LSC-30028 |
Advances in Medicine |
O |
M
|
7.5 |
15 |
|
|
This module will describe and promote the understanding of advances in medicine that have impacted on diagnosis, treatment, prevention of a range of diseases. It will highlight fast emerging areas of research which are striving to improve diagnosis including nanotechnology and new biochemical tests in the fields of heart disease, cancer and fertility investigations which will potentially improve patient care. The module will provide insight into the advancing field of Personalised Medicine, which allows optimisation of treatment based on an individual&©s genetic and clinical information and also an area of cutting edge research into the use of non-coding RNA as a therapeutic tool. The module will also provide an opportunity to discuss new developments in the fields of Tissue engineering and Stem cell technologies, which have seen huge advances in recent years.
All the sessions will be in the form of lectures or case studies and will be delivered by academics and Clinical Scientists who are currently engaged in active research in these fast moving areas. There will be tutorial sessions which will provide a forum for discussion of some of the topics covered in this module. In addition there will be opportunities for the student to appraise the current thinking in these areas and develop and present their own views in the form of an oral and poster presentations.
Indicative content includes:
Stem cells for the treatment of neurodegenerative diseases
Stem cells for the treatment of musculoskeletal disorders
Advances in Clinical Diagnostic Medicine
Magnetic Nanoparticles in Biology and Medicine
Developments of new biochemistry tests and their translation into routine clinical practice
Non-coding RNA and its potential as a therapeutic tool.
|
|
#
|
LSC-30028 |
Advances in Medicine |
EP |
M
|
7.5 |
15 |
|
|
This module will describe and promote the understanding of advances in medicine that have impacted on diagnosis, treatment, prevention of a range of diseases. It will highlight fast emerging areas of research which are striving to improve diagnosis including nanotechnology and new biochemical tests in the fields of heart disease, cancer and fertility investigations which will potentially improve patient care. The module will provide insight into the advancing field of Personalised Medicine, which allows optimisation of treatment based on an individual&©s genetic and clinical information and also an area of cutting edge research into the use of non-coding RNA as a therapeutic tool. The module will also provide an opportunity to discuss new developments in the fields of Tissue engineering and Stem cell technologies, which have seen huge advances in recent years.
All the sessions will be in the form of lectures or case studies and will be delivered by academics and Clinical Scientists who are currently engaged in active research in these fast moving areas. There will be tutorial sessions which will provide a forum for discussion of some of the topics covered in this module. In addition there will be opportunities for the student to appraise the current thinking in these areas and develop and present their own views in the form of an oral and poster presentations.
Indicative content includes:
Stem cells for the treatment of neurodegenerative diseases
Stem cells for the treatment of musculoskeletal disorders
Advances in Clinical Diagnostic Medicine
Magnetic Nanoparticles in Biology and Medicine
Developments of new biochemistry tests and their translation into routine clinical practice
Non-coding RNA and its potential as a therapeutic tool.
|
|
#
|
LSC-30036 |
Human Parasitology |
O |
M
|
7.5 |
15 |
|
|
This module will promote the understanding of the theoretical and practical aspects of Parasitic diseases of Humans with particular reference to protozoan, helminth and nematode infections. Protozoan infections will include Malaria and Leishmaniasis. Other infections covered will be Shistsomiasis (blood fluke) and Filariasis (worm). The module will address the life cycle of the parasites, which is critical to understanding how the parasite is transmitted, pathogenesis of the parasitic infection and diagnosis and treatment. A basic understanding of immunology will be useful in understanding the human host-parasite interactions that determine pathology in these parasitic infections. Understanding of the parasite life cycles will also be important in grasping the current methods of controlling transmission and also the infection. The module will also address challenges to effective delivery of treatment and control of transmission, including socio-economic and cultural issues. The module will be delivered by academics who are currently active in Parasitology and Entomology research and will be able to provide an insight into the current developments and knowledge of these parasitic diseases. There will be tutorial sessions which will provide a forum for discussion of some of the topics covered in this module. Additional practical sessions will provide the opportunity to examine specimens and discuss film material, which will enhance the students&© understanding of Human Parasitology.
Indicative content includes:
Comparative overview of life cycles of parasites with particular emphasis on Malaria, Leishmaniasis, Schistosomiasis (blood flukes) and Filariasis (worm).
Human host-parasite interactions in parasitic infections:
Immune response
Immunosuppression and co-infection
Immunity and vaccine development and associated problems.
Pathology and symptoms of Parasitic infections, discuss and compare current knowledge of mechanisms involved in pathogenesis, also discuss symptomatic versus asymptomatic infection tissue damage, anaemia, organ-failure.
Diagnosis of parasitic infections in the field and in the laboratory and discuss invasive and non-invasive methods of diagnosis (blood smear, ELISA for parasite antigens, urine, stool, tissue biopsy, ocular imaging).
Treatment of parasitic infections, discussing prophylactic measures available and chemotherapy regimens with particular reference to mode of action of the drugs, problems such as drug resistance
Socio-economic problems associated with effective delivery of treatment such as accessibility of treatment, cost of treatment, compliance with treatment.
Vector Biology
Control of Transmission, vector avoidance, prevention of transmission, socio-economic and cultural problems associated with use of preventive measures e.g. (bed nets: cost, child versus adult, health education).
|
|
#
|
LSC-30036 |
Human Parasitology |
EP |
M
|
7.5 |
15 |
|
|
This module will promote the understanding of the theoretical and practical aspects of Parasitic diseases of Humans with particular reference to protozoan, helminth and nematode infections. Protozoan infections will include Malaria and Leishmaniasis. Other infections covered will be Shistsomiasis (blood fluke) and Filariasis (worm). The module will address the life cycle of the parasites, which is critical to understanding how the parasite is transmitted, pathogenesis of the parasitic infection and diagnosis and treatment. A basic understanding of immunology will be useful in understanding the human host-parasite interactions that determine pathology in these parasitic infections. Understanding of the parasite life cycles will also be important in grasping the current methods of controlling transmission and also the infection. The module will also address challenges to effective delivery of treatment and control of transmission, including socio-economic and cultural issues. The module will be delivered by academics who are currently active in Parasitology and Entomology research and will be able to provide an insight into the current developments and knowledge of these parasitic diseases. There will be tutorial sessions which will provide a forum for discussion of some of the topics covered in this module. Additional practical sessions will provide the opportunity to examine specimens and discuss film material, which will enhance the students&© understanding of Human Parasitology.
Indicative content includes:
Comparative overview of life cycles of parasites with particular emphasis on Malaria, Leishmaniasis, Schistosomiasis (blood flukes) and Filariasis (worm).
Human host-parasite interactions in parasitic infections:
Immune response
Immunosuppression and co-infection
Immunity and vaccine development and associated problems.
Pathology and symptoms of Parasitic infections, discuss and compare current knowledge of mechanisms involved in pathogenesis, also discuss symptomatic versus asymptomatic infection tissue damage, anaemia, organ-failure.
Diagnosis of parasitic infections in the field and in the laboratory and discuss invasive and non-invasive methods of diagnosis (blood smear, ELISA for parasite antigens, urine, stool, tissue biopsy, ocular imaging).
Treatment of parasitic infections, discussing prophylactic measures available and chemotherapy regimens with particular reference to mode of action of the drugs, problems such as drug resistance
Socio-economic problems associated with effective delivery of treatment such as accessibility of treatment, cost of treatment, compliance with treatment.
Vector Biology
Control of Transmission, vector avoidance, prevention of transmission, socio-economic and cultural problems associated with use of preventive measures e.g. (bed nets: cost, child versus adult, health education).
|
|
|
LSC-30038 |
Double Applied Life Sciences Placement - ISP |
O |
C
|
15 |
30 |
|
|
A double placement research project is an opportunity for students to carry out a substantial piece of meaningful research at a host industrial, governmental or academic partner either within the UK or another European State. Students will get a taste of what it is like to work in a real research environment and obtain substantial employment skills whilst on placement and during their report preparation. Students will work independently on a research project under the supervision of a member of academic staff from the School of Life Sciences and the host partner. Research topics are offered in a range of subject areas and incorporate training in generic and specialised scientific skills. |
| Semester 1-2 |
C/O |
TYP |
ECTS | CATS |
|
#
|
LSC-30008 |
Research Project 1 - ISP |
O |
C
|
7.5 |
15 |
|
|
In the first two years of the course, students have developed a range of technical and analytical skills by following established protocols in large laboratory classes. In the final year project, students will get a taste of what it is like to work in a real research environment by working on their own specific research topic under the supervision of a member of academic staff from the School of Life Sciences or the Institute for Science and Technology in Medicine (ISTM). The topics are set by the supervisors and are designed to allow the students to expand their portfolio of technical expertise and to apply that expertise to investigate a research question. The very varied list of topics reflects the diversity of reseach interests within the School and ISTM. Students will be expected to spend the equivalent of 1 day per week, which may be spread over several days, working in the laboratory during semester 1. In semester 2 they will write a report where they present and interpret the results of their experiments and place them in context with existing literature in the field. |
|
+
|
LSC-30014 |
Biochemistry Research Project (non-experimental) - ISP |
O |
C
|
7.5 |
15 |
|
|
This module aims to introduce students to some of the key non-experimental research skills that are routinely used by biochemists and biomedical scientists, such as in depth literature searching, analysis of experimental data and the use of a computer as tool for both reseach (bioinformatics) and dissemination of information (web page construction). The student will research the literature on a specific topic, using library and web based resources and will produce a written review. In addition, the student will either process and interpret some raw experimental data provided to them or complete a computer task such as using bioinformatics programmes or producing a web page. |
|
|
LSC-30035 |
Double Biochemistry Research Project - ISP |
O |
C
|
15 |
30 |
|
|
In the first two years of the course, students have developed a range of technical and analytical skills by following established protocols in large laboratory classes. In the final year project, students will get a taste of what it is like to work in a real research environment by working on their own specific research topic under the supervision of a member of academic staff from the School of Life Sciences or the Institute for Science and Technology in Medicine (ISTM). The topics are set by the supervisors and are designed to allow the students to expand their portfolio of technical expertise and to apply that expertise to investigate a research question. The very varied list of topics reflects the diversity of research interests within the School and ISTM. Students will be expected to spend the equivalent of 2 days per week, which may be spread over several days working in the laboratory during semester 1. In semester 2 they will write a report where they present and interpret the results of their experiments and place them in context with existing literature in the field. |
| Semester 2 |
C/O |
TYP |
ECTS | CATS |
|
~
|
LSC-30009 |
Clinical Pathology |
O |
M
|
7.5 |
15 |
|
|
The majority of staff that contribute to the module are employees of the University Hospital of North Staffordshire (UHNS). In these cases, their principle responsibilities are towards patient care and well-being. These staff, therefore, hold significant posts across a spectrum of clinical and clinical related areas. Students will benefit from lectures and expertise in Clinical Diagnostic Pathology,Pharmacology, Biochemistry, Genetics and Inflammatory Diseases. Students will gain insight how patients from their initial presentation at the UHNS are managed from the perspective of diagnosis and treatment. The course will cover both standardised testing options and the development of new diagnostic procedures with a particular emphasis on genetic and epigenetic aspects of disease. Student will also gain an appreciation of the cost benefit of particular routes for diagnosis and treatment and the importance of identifying false positive and false negative results. Finally, the students will have the opportunity to perform their own extensive literature review of a disease related topic that is not covered by the course through formal lectures. |
|
~
|
LSC-30009 |
Clinical Pathology |
EP |
M
|
7.5 |
15 |
|
|
The majority of staff that contribute to the module are employees of the University Hospital of North Staffordshire (UHNS). In these cases, their principle responsibilities are towards patient care and well-being. These staff, therefore, hold significant posts across a spectrum of clinical and clinical related areas. Students will benefit from lectures and expertise in Clinical Diagnostic Pathology,Pharmacology, Biochemistry, Genetics and Inflammatory Diseases. Students will gain insight how patients from their initial presentation at the UHNS are managed from the perspective of diagnosis and treatment. The course will cover both standardised testing options and the development of new diagnostic procedures with a particular emphasis on genetic and epigenetic aspects of disease. Student will also gain an appreciation of the cost benefit of particular routes for diagnosis and treatment and the importance of identifying false positive and false negative results. Finally, the students will have the opportunity to perform their own extensive literature review of a disease related topic that is not covered by the course through formal lectures. |
|
|
LSC-30010 |
Biochemistry in Practice: Acquisition, Analysis and Communication of Information |
C |
M
|
7.5 |
15 |
|
|
The module aims to develop the skills needed to effectively communicate scientific knowledge. It begins with a hands-on mini project involving the acquisition of sequence information from remote
databases and the subsequent analysis using bioinformatics tools. This is followed by advanced training in the skills required for communicating scientific information verbally, visually and in writing
and culminates in student verbal and visual presentations. Also included is training and practice in the analysis of published information, a skill of particular importance, even for those entering
careers that do not involve practical experimental work. |
|
#
|
LSC-30015 |
Biology of Disease - ISP |
EP |
C
|
7.5 |
15 |
|
|
This module gives students the opportunity to investigate a specific disease topic from a range of options provided and is designed to allow the students to adopt a self-learning approach in which they will conduct their own research on a defined topic in consultation with the module manager. The module consists of the preparation of an independently researched critical appraisal, in the form of a 4000-5000 word essay, of the current level of understanding of a particular disease along with tutorials based on student-centred learning. The tutorial sessions provide a forum for addressing problems, for assessing and monitoring progress, and for developing the required skills. Tutorial sessions include topics on information and retrieval, improving essays and discussion of their essay outlines. |
|
#
|
LSC-30018 |
Biochemistry and Therapy of Disease |
O |
M
|
7.5 |
15 |
|
|
This module is intended to describe and promote understanding of the
molecular basis of therapeutic intervention in a range of diseases,
including bacterial, neurodegenerative, parasitic and neoplastic
pathologies. It will also address the questions arising from the failure of
disease therapies and describe the molecular events underlying
resistance to therapy.
2 lectures |
|
#
|
LSC-30018 |
Biochemistry and Therapy of Disease |
EP |
M
|
7.5 |
15 |
|
|
This module is intended to describe and promote understanding of the
molecular basis of therapeutic intervention in a range of diseases,
including bacterial, neurodegenerative, parasitic and neoplastic
pathologies. It will also address the questions arising from the failure of
disease therapies and describe the molecular events underlying
resistance to therapy.
2 lectures |
Biochemistry Minor - Level 1 Modules
| Semester 1 |
C/O |
TYP |
ECTS | CATS |
|
|
LSC-10027 |
Metabolism: Major Metabolic Pathways |
C |
M
|
7.5 |
15 |
|
|
All living things are packets of energy and the challenge of life and living is how energy can be used and controlled effectively. Human beings derive most but not all of their energy from diet, the processing of all that we eat and drink. How we use and control energy is essentially described by our metabolism and this is the subject of this module. We find that the human body cycles and recycles energy more effectively than any machine or government energy policy. We are experts in using energy effectively, conservatively and creatively. Sometimes something goes wrong in our energy cycling and this leads to metabolic disorders including conditions as seemingly diverse as obesity and neurological disease and some examples of such are included in the module. Overall we will learn and appreciate just how important energy cycling is in the effective human being and indeed all life forms. There is little more important in biochemical science than this and that is why this module provides the basis for biochemistry and biomedical sciences at Keele. |
|
|
LSC-10034 |
Natures Tools: Proteins & Enzymes |
C |
M
|
7.5 |
15 |
|
|
This module is all about proteins. Proteins are intimately involved in all cellular processes. They help to form and maintain cell structure, catalyse metabolic reactions, transport materials in and out of organelles, transduce signals and regulate gene expression.
Great progress has been made in understanding the molecular structure of proteins, and we are now able to visualise many of them in great detail. Knowing the structure helps us to understand how a protein functions, and the content of the module reflects these two aspects. The first part deals with protein structure, and why proteins adopt a certain unique shape. The second part of the module explores how the function of some proteins, particularly enzymes, can be understood in terms of their structure. Concepts and ideas you encounter here underpin the remainder of the course, and and the relationship between protein structure and function will be developed in future modules at level 5 and 6.
|
| Semester 2 |
C/O |
TYP |
ECTS | CATS |
|
|
LSC-10036 |
Cells and Organelles : Biochemical Aspects of Cell Biology |
C |
M
|
7.5 |
15 |
|
|
This module is an introduction to cell biology. A cell is the unit of life, and is amazingly complex. However a living cell can be understood in terms of the different functions carried out by its organelles integrated by the exchange of molecules and information across cellular membranes. The module therefore begins by considering the diversity of cells and the biochemical and structural features of prokaryotic cells and eukaryotic cells. The specialised biochemistry of intracellular organelles will be discussed together with important adaptations of bacteria and fungi. The structure and properties of cellular membranes are then discussed together with the mechanisms that cells have devised to allow transport of molecules cross membranes. It concludes with an introduction to cell signalling, and the mechanisms by which cells receive chemical and hormonal signals and transduce their message as a cellular response. |
|
|
LSC-10038 |
Information and Inheritance |
C |
M
|
7.5 |
15 |
|
|
This module, focusing on our genetic blueprint, aims to answer a number of questions:
- What is the molecular structure of a gene?
- How is this information inherited during cell division and during fertilisation of higher species?
- How is this information read in order to make the proteins of each cell; how is this process controlled?
- What role does gene mutation play in health and disease?
It consists of lectures, hands on laboratory sessions, problem based small group and class tutorials and substantial KLE based learning resources. Laboratory practical sessions on molecular and microbiology techniques, including a 3D molecular graphics session on DNA structure and function, complement the theory. A Bioethics extraordinary lecture provides an opportunity to become aware of the ethical and legal implications posed by using model organisms in the quest for knowing our genomes.
|
Biochemistry Minor - Level 2 Modules
| Semester 1 |
C/O |
TYP |
ECTS | CATS |
|
~
|
LSC-20003 |
Gene and Protein Engineering |
C |
M
|
7.5 |
15 |
|
|
This module covers one of the most exciting and innovative areas of
biochemistry and will acquaint students with the theory, techniques
and applications of genetic engineering. The course will describe
advanced techniques of gene structural analysis, cloning, and
expression in host organisms. The manipulation of gene and protein
sequences will be discussed, along with recent developments in
biotechnology and medical genetics. |
|
+
|
LSC-20015 |
Molecular, Cellular and Structural Immunology |
C |
M
|
7.5 |
15 |
|
|
This module gives students a consideration of how the mammalian body copes with infection by various pathogens and includes an understanding of the cellular basis of the immune system and the generation and selection of the immune repertoire. It also provides a general qualitative overview of the methods and techniques of protein crystallography, followed by functional insights on immune protein structure. |
|
|
LSC-20017 |
Biochemistry - Study Abroad I |
EP |
C
|
7.5 |
15 |
|
|
This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. |
|
|
LSC-20018 |
Biochemistry - Study Abroad II |
EP |
C
|
7.5 |
15 |
|
|
This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. |
| Semester 2 |
C/O |
TYP |
ECTS | CATS |
|
~
|
LSC-20005 |
Endocrinology and Cell Signalling |
C |
M
|
7.5 |
15 |
|
|
This module will explore some of the ways in which cells transmit, receive and interpret signals. You will consider how information is encoded, secreted and transmitted to target cells and how incoming signals are recognised and transduced into meaningful information, to elicit the appropriate responses of target cells to signals. Specific details of a number of mammalian cell signalling pathways are used to illustrate principles and concepts and may include G-protein coupled receptor signalling, examples of second messengers, such as the inositol phosphates, insulin signalling as an example of receptor tyrosine kinase signalling and the regulation of gene transcription in mediating the actions of lipophilic hormones.
|
|
+
|
LSC-20016 |
Metabolism in Health and Disease |
C |
M
|
7.5 |
15 |
|
|
This module will describe and explain the specialisation and
interdependence of metabolism within the bodies of mammals and of
man: homeostasis; adaptation to nutritional state; elimination of
drugs and harmful substances and will explore the issues
surrounding the changes in metabolism associated with inherited
and acquired disease.
|
|
|
LSC-20036 |
Biochemistry - Study Abroad III |
EP |
C
|
7.5 |
15 |
|
|
This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. |
|
|
LSC-20037 |
Biochemistry - Study Abroad IV |
EP |
C
|
7.5 |
15 |
|
|
This is a module that is automatically allocated to the records our Keele level II students who are going to Study Abroad at a partner University for a semester of their second year and cannot be selected by any other level II students. |
Biochemistry Minor - Level 3 Modules
| Semester 1 |
C/O |
TYP |
ECTS | CATS |
|
#
|
LSC-30016 |
Structural Biology & Macromolecular Function |
EP |
M
|
7.5 |
15 |
|
|
Advances in biotechnology, biology and biomedicine, and their impact on the quality of life, the economy, medicine and health care increasingly depend on the application of structural biology which provides detailed three-dimensional structural information at the atomic level of the proteins which are central to all life processes. While structural biology includes a variety of different techniques such as crystallography and electron microscopy, this module concentrates on the outcomes of these techniques rather than the techniques themselves, with in-depth analysis of how proteins, enzymes and viruses recognise and bind their targets, and how detailed structural information is used to intervene in or enhance these processes. An important aspect of health and well being in all forms of life is the ability to prevent, resist, fight and recover from infection and disease, and much of the course concentrates on how an increased understanding of the molecular mechanisms involved provides a unique opportunity for the design of potential diagnostic and therapeutic agents and strategies. |
| Semester 2 |
C/O |
TYP |
ECTS | CATS |
|
~
|
LSC-30009 |
Clinical Pathology |
EP |
M
|
7.5 |
15 |
|
|
The majority of staff that contribute to the module are employees of the University Hospital of North Staffordshire (UHNS). In these cases, their principle responsibilities are towards patient care and well-being. These staff, therefore, hold significant posts across a spectrum of clinical and clinical related areas. Students will benefit from lectures and expertise in Clinical Diagnostic Pathology,Pharmacology, Biochemistry, Genetics and Inflammatory Diseases. Students will gain insight how patients from their initial presentation at the UHNS are managed from the perspective of diagnosis and treatment. The course will cover both standardised testing options and the development of new diagnostic procedures with a particular emphasis on genetic and epigenetic aspects of disease. Student will also gain an appreciation of the cost benefit of particular routes for diagnosis and treatment and the importance of identifying false positive and false negative results. Finally, the students will have the opportunity to perform their own extensive literature review of a disease related topic that is not covered by the course through formal lectures. |
|
|
LSC-30010 |
Biochemistry in Practice: Acquisition, Analysis and Communication of Information |
EP |
M
|
7.5 |
15 |
|
|
The module aims to develop the skills needed to effectively communicate scientific knowledge. It begins with a hands-on mini project involving the acquisition of sequence information from remote
databases and the subsequent analysis using bioinformatics tools. This is followed by advanced training in the skills required for communicating scientific information verbally, visually and in writing
and culminates in student verbal and visual presentations. Also included is training and practice in the analysis of published information, a skill of particular importance, even for those entering
careers that do not involve practical experimental work. |
|
#
|
LSC-30018 |
Biochemistry and Therapy of Disease |
EP |
M
|
7.5 |
15 |
|
|
This module is intended to describe and promote understanding of the
molecular basis of therapeutic intervention in a range of diseases,
including bacterial, neurodegenerative, parasitic and neoplastic
pathologies. It will also address the questions arising from the failure of
disease therapies and describe the molecular events underlying
resistance to therapy.
2 lectures |
